| For: |
Zhu BH, Chen HY, Zhan WH, Wang CY, Cai SR, Wang Z, Zhang CH, He YL. (-)-Epigallocatechin-3-gallate inhibits VEGF expression induced by IL-6 |
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| URL: | https://www.wjgnet.com/1007-9327/full/v17/i18/2315.htm |
| Number | Citing Articles |
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Chien-Hung Lin, Hsin-Hui Wang, Tsung-Hsien Chen, Ming-Chang Chiang, Peir-Haur Hung, Yann-Jang Chen. Involvement of MicroRNA-296 in the Inhibitory Effect of Epigallocatechin Gallate against the Migratory Properties of Anoikis-Resistant Nasopharyngeal Carcinoma Cells. Cancers 2020; 12(4) doi: 10.3390/cancers12040973
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F Kosova, FO Kurt, E Olmez, I Tuğlu, Z Arı. Effects of caffeic acid phenethyl ester on matrix molecules and angiogenetic and anti-angiogenetic factors in gastric cancer cells cultured on different substrates. Biotechnic & Histochemistry 2016; 91(1) doi: 10.3109/10520295.2015.1072769
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Najmeh Kaffash Farkhad, Majid Asadi-Samani, Fatemeh Asadi-Samani, Hossein Asadi-Samani. Plant Antioxidants and Health. Reference Series in Phytochemistry 2021; doi: 10.1007/978-3-030-45299-5_16-1
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Galina Sufianova, Ilgiz Gareev, Ozal Beylerli, Jianing Wu, Alina Shumadalova, Albert Sufianov, Xin Chen, Shiguang Zhao. Modern aspects of the use of natural polyphenols in tumor prevention and therapy. Frontiers in Cell and Developmental Biology 2022; 10 doi: 10.3389/fcell.2022.1011435
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Yu Qian, Jing Zhang, Xinwei Fu, Ruokun Yi, Peng Sun, Mei Zou, Xingyao Long, Xin Zhao. Preventive Effect of Raw Liubao Tea Polyphenols on Mouse Gastric Injuries Induced by HCl/Ethanol via Anti-Oxidative Stress. Molecules 2018; 23(11) doi: 10.3390/molecules23112848
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Ren-You Gan, Hua-Bin Li, Zhong-Quan Sui, Harold Corke. Absorption, metabolism, anti-cancer effect and molecular targets of epigallocatechin gallate (EGCG): An updated review. Critical Reviews in Food Science and Nutrition 2018; 58(6) doi: 10.1080/10408398.2016.1231168
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Yanling Ai, Ziyi Zhao, Hengyi Wang, Xiaomei Zhang, Weihan Qin, Yanlei Guo, Maoyuan Zhao, Jianyuan Tang, Xiao Ma, Jinhao Zeng. Pull the plug: Anti‐angiogenesis potential of natural products in gastrointestinal cancer therapy. Phytotherapy Research 2022; 36(9) doi: 10.1002/ptr.7492
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Ehsan Ghaedi, Nima Rezaei, Maryam Mahmoudi. Nutrition and Immunity. 2019; doi: 10.1007/978-3-030-16073-9_12
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Payal Bajaj, Ajay Kumar, Brahmjot Singh, Varinder Kaur, Bunty Sharma, Purnima Jindal, Shafiul Haque, Hardeep Singh Tuli. Immunomodulatory Phytochemicals in Cancer: Mechanistic Pathways and Translational Potential. Chemistry & Biodiversity 2026; 23(2) doi: 10.1002/cbdv.202502737
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YANG WANG, XUEQUN REN, CHAOYANG DENG, LU YANG, ERFU YAN, TAO GUO, YANMIN LI, MARVIN XUEJUN XU. Mechanism of the inhibition of the STAT3 signaling pathway by EGCG. Oncology Reports 2013; 30(6) doi: 10.3892/or.2013.2743
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Anja Mähler, Jochen Steiniger, Markus Bock, Lars Klug, Nadine Parreidt, Mario Lorenz, Benno F Zimmermann, Alexander Krannich, Friedemann Paul, Michael Boschmann. Metabolic response to epigallocatechin-3-gallate in relapsing-remitting multiple sclerosis: a randomized clinical trial. The American Journal of Clinical Nutrition 2015; 101(3) doi: 10.3945/ajcn.113.075309
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Hoda I. Bahr, Eman A. Toraih, Eman A. Mohammed, Hala M.F. Mohammad, Eman A.I. Ali, Sawsan A. Zaitone. Chemopreventive effect of leflunomide against Ehrlich's solid tumor grown in mice: Effect on EGF and EGFR expression and tumor proliferation. Life Sciences 2015; 141 doi: 10.1016/j.lfs.2015.10.003
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Yan Ma, Jingya Yang, Shiyi Li, Wenjuan Yu. Synergic Inhibition of Lung Carcinoma 95-D Cell Proliferation and Invasion by Combination with (−)-Epigallocatechin-3-Gallate and Ascorbic Acid. Wuhan University Journal of Natural Sciences 2018; 23(3) doi: 10.1007/s11859-018-1321-2
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Wen-Xiang Cheng, Huan Huang, Jian-Hai Chen, Tian-Tian Zhang, Guo-Yuan Zhu, Zheng-Tan Zheng, Jie-Tao Lin, Yi-Ping Hu, Yong Zhang, Xue-Ling Bai, Yan Wang, Zhan-Wang Xu, Bing Song, Yi-Ying Mao, Fei Yang, Peng Zhang. Genistein inhibits angiogenesis developed during rheumatoid arthritis through the IL-6/JAK2/STAT3/VEGF signalling pathway. Journal of Orthopaedic Translation 2020; 22 doi: 10.1016/j.jot.2019.07.007
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Sandeep Kaur, Sheikh Showkat Ahmad, Vaseem Raja, Priyanka Mahajan, Gholamreza Abdi. Deciphering the cancer chemopreventive potential of phytochemicals: an integrative perspective on molecular targets and signaling networks. Cancer Cell International 2026; 26(1) doi: 10.1186/s12935-025-04109-x
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Gina Abdelaal, Stephany Veuger. Reversing oncogenic transformation with iron chelation. Oncotarget 2021; 12(2) doi: 10.18632/oncotarget.27866
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Ya-Jun Li, Shun-Long Wu, Song-Mei Lu, Fang Chen, Ying Guo, Sheng-Min Gan, Yan-Long Shi, Shuang Liu, Shao-Lin Li. (-)-Epigallocatechin-3-gallate inhibits nasopharyngeal cancer stem cell self-renewal and migration and reverses the epithelial–mesenchymal transition via NF-κB p65 inactivation. Tumor Biology 2015; 36(4) doi: 10.1007/s13277-014-2899-4
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Shiv Govind Rawat, Rajan Kumar Tiwari, Pratishtha Sonker, Rajendra Prakash Maurya, Naveen Kumar Vishvakarma, Ajay Kumar. Obesity and Cancer. 2021; doi: 10.1007/978-981-16-1846-8_11
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Changwei Liu, Penghui Li, Zhihao Qu, Wei Xiong, Ailing Liu, Sheng Zhang. Advances in the Antagonism of Epigallocatechin-3-gallate in the Treatment of Digestive Tract Tumors. Molecules 2019; 24(9) doi: 10.3390/molecules24091726
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Aastha Guleria, Akhil Kamboj, Jyotsana Kaushal, Kumari Anupam, Archana Bhatnagar. A Molecular Insight into Significance of Functional Foods in Better Management of Rheumatoid Arthritis. Revista Brasileira de Farmacognosia 2022; 32(4) doi: 10.1007/s43450-022-00266-6
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| 22 |
Md. Abdul Aziz, Md. Shahid Sarwar, Tahmina Akter, Md. Sahab Uddin, Song Xun, Yu Zhu, Mohammad Safiqul Islam, Zhang Hongjie. Polyphenolic molecules targeting STAT3 pathway for the treatment of cancer. Life Sciences 2021; 268 doi: 10.1016/j.lfs.2020.118999
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| 23 |
Mohammad Yasin Zamanian, Klavdiya A. Turkadze, Mehraveh Sadeghi Ivraghi, Maryam Golmohammadi, Maryam Sharifi, Zahra Keshtpour Amlashi. Curcumin and Resveratrol as Dual Modulators of the STAT3 Pathway in Lung Cancer: A Comprehensive Review. Food Science & Nutrition 2025; 13(9) doi: 10.1002/fsn3.70829
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Wenhao Liao, Jing Wang, Yuchen Li. Natural products based on Correa's cascade for the treatment of gastric cancer trilogy: Current status and future perspective. Journal of Pharmaceutical Analysis 2025; 15(2) doi: 10.1016/j.jpha.2024.101075
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| 25 |
Seon-Yeong Lee, Young Ok Jung, Jun-Geol Ryu, Hye-Jwa Oh, Hye-Jin Son, Seung Hoon Lee, Jeong-Eun Kwon, Eun-Kyung Kim, Mi-Kyung Park, Sung-Hwan Park, Ho-Youn Kim, Mi-La Cho. Epigallocatechin-3-gallate ameliorates autoimmune arthritis by reciprocal regulation of T helper-17 regulatory T cells and inhibition of osteoclastogenesis by inhibiting STAT3 signaling. Journal of Leukocyte Biology 2016; 100(3) doi: 10.1189/jlb.3A0514-261RR
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| 26 |
Moon Kyung Joo, Jong-Jae Park, Hoon Jai Chun. Recent updates of precision therapy for gastric cancer: Towards optimal tailored management. World Journal of Gastroenterology 2016; 22(19): 4638-4650 doi: 10.3748/wjg.v22.i19.4638
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B. N. Singh, Harikesh Bahadur Singh, A. Singh, Alim H. Naqvi, Braj Raj Singh. Dietary phytochemicals alter epigenetic events and signaling pathways for inhibition of metastasis cascade. Cancer and Metastasis Reviews 2014; 33(1) doi: 10.1007/s10555-013-9457-1
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MOON KYUNG JOO, JONG-JAE PARK, SUNG HO KIM, HYO SOON YOO, BEOM JAE LEE, HOON JAI CHUN, SANG WOO LEE, YOUNG-TAE BAK. Antitumorigenic effect of plumbagin by induction of SH2-containing protein tyrosine phosphatase 1 in human gastric cancer cells. International Journal of Oncology 2015; 46(6) doi: 10.3892/ijo.2015.2935
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| 29 |
Chhavi Sharma, Qurrat El-Ain Nusri, Salema Begum, Elham Javed, Tahir A. Rizvi, Arif Hussain. (-)-Epigallocatechin-3-Gallate Induces Apoptosis and Inhibits Invasion and Migration of Human Cervical Cancer Cells. Asian Pacific Journal of Cancer Prevention 2012; 13(9) doi: 10.7314/APJCP.2012.13.9.4815
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| 30 |
Mohammed N. Salman, Fouad Razzaq Al‐Burki, Hazim Ali Hussein, Laith A. Younus, Fadhil A. Nasser, Hasanain A. A. Almohseni. Effect of Epigallocatechin‐3‐Gallate on Depression‐Related Cytokines in Thalassemia Patients: Molecular and Cellular Evaluation. Journal of Clinical Laboratory Analysis 2026; 40(4) doi: 10.1002/jcla.70171
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Rosa Direito, João Rocha, Bruno Sepodes, Maria Eduardo-Figueira. Phenolic Compounds Impact on Rheumatoid Arthritis, Inflammatory Bowel Disease and Microbiota Modulation. Pharmaceutics 2021; 13(2) doi: 10.3390/pharmaceutics13020145
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Jing Chen, Jieqiong Wang, Lei Lin, Lijun He, Yuanyuan Wu, Li Zhang, Zhengfang Yi, Yihua Chen, Xiufeng Pang, Mingyao Liu. Inhibition of STAT3 Signaling Pathway by Nitidine Chloride Suppressed the Angiogenesis and Growth of Human Gastric Cancer. Molecular Cancer Therapeutics 2012; 11(2) doi: 10.1158/1535-7163.MCT-11-0648
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Kyung-Soo Chun, Eun-Hee Kim, Sooyeon Lee, Ki Baik Hahm. Chemoprevention of Gastrointestinal Cancer: The Reality and the Dream. Gut and Liver 2013; 7(2) doi: 10.5009/gnl.2013.7.2.137
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Lucie Trnková, Daniela Ricci, Caterina Grillo, Gianni Colotti, Fabio Altieri. Green tea catechins can bind and modify ERp57/PDIA3 activity. Biochimica et Biophysica Acta (BBA) - General Subjects 2013; 1830(3) doi: 10.1016/j.bbagen.2012.11.011
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Donato F. Romagnolo, Ornella I. Selmin. Flavonoids and Cancer Prevention: A Review of the Evidence. Journal of Nutrition in Gerontology and Geriatrics 2012; 31(3) doi: 10.1080/21551197.2012.702534
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Manzar Alam, Sabeeha Ali, Ghulam Md. Ashraf, Anwar L. Bilgrami, Dharmendra Kumar Yadav, Md. Imtaiyaz Hassan. Epigallocatechin 3-gallate: From green tea to cancer therapeutics. Food Chemistry 2022; 379 doi: 10.1016/j.foodchem.2022.132135
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Mariangela Rondanelli, Annalisa Opizzi, Simone Perna, Milena Faliva, Sebastiano Bruno Solerte, Marisa Fioravanti, Catherine Klersy, Cava Edda, Paolini Maddalena, Scavone Luciano, Ceccarelli Paola, Castellaneta Emanuela, Savina Claudia, Lorenzo Maria Donini. Improvement in insulin resistance and favourable changes in plasma inflammatory adipokines after weight loss associated with two months’ consumption of a combination of bioactive food ingredients in overweight subjects. Endocrine 2013; 44(2) doi: 10.1007/s12020-012-9863-0
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Ladislav Mirossay, Lenka Varinská, Ján Mojžiš. Antiangiogenic Effect of Flavonoids and Chalcones: An Update. International Journal of Molecular Sciences 2017; 19(1) doi: 10.3390/ijms19010027
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Daniela Mokra, Marta Joskova, Juraj Mokry. Therapeutic Effects of Green Tea Polyphenol (‒)-Epigallocatechin-3-Gallate (EGCG) in Relation to Molecular Pathways Controlling Inflammation, Oxidative Stress, and Apoptosis. International Journal of Molecular Sciences 2022; 24(1) doi: 10.3390/ijms24010340
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Carmen Tse, Ashleigh Warner, Rufaik Farook, James G Cronin. Phytochemical Targeting of STAT3 Orchestrated Lipid Metabolism in Therapy-Resistant Cancers. Biomolecules 2020; 10(8) doi: 10.3390/biom10081118
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Milad Ashrafizadeh, Ali Zarrabi, Sima Orouei, Vahideh Zarrin, Ebrahim Rahmani Moghadam, Amirhossein Zabolian, Shima Mohammadi, Kiavash Hushmandi, Yashar Gharehaghajlou, Pooyan Makvandi, Masoud Najafi, Reza Mohammadinejad. STAT3 Pathway in Gastric Cancer: Signaling, Therapeutic Targeting and Future Prospects. Biology 2020; 9(6) doi: 10.3390/biology9060126
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T. Gürpınar, F. Kosova, F. O. Kurt, S. U. Cambaz, A. T. Yücel, N. Umur, M. I. Tuğlu. Effect of geldanamycin on the expression of the matrix molecules and angiogenetic factors in a gastric cancer cell line. Biotechnic & Histochemistry 2021; 96(2) doi: 10.1080/10520295.2020.1772507
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Emmanuele D. S. Andrade, Ronimara A. Santos, Landi V. C. Guillermo, Noriyuki Miyoshi, Danielly C. Ferraz da Costa. Immunomodulatory Effects of Green Tea Catechins and Their Ring Fission Metabolites in a Tumor Microenvironment Perspective. Molecules 2024; 29(19) doi: 10.3390/molecules29194575
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Andrew S Giraud, Trevelyan R Menheniott, Louise M Judd. Targeting STAT3 in gastric cancer. Expert Opinion on Therapeutic Targets 2012; 16(9) doi: 10.1517/14728222.2012.709238
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Yu-Hsin Lin, Chun-Lung Feng, Chih-Ho Lai, Jui-Hsiang Lin, Hao-Yun Chen. Preparation of epigallocatechin gallate-loaded nanoparticles and characterization of their inhibitory effects onHelicobacter pylorigrowthin vitroandin vivo. Science and Technology of Advanced Materials 2014; 15(4) doi: 10.1088/1468-6996/15/4/045006
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Jonathan Michaud-Levesque, Nathalie Bousquet-Gagnon, Richard Béliveau. Quercetin abrogates IL-6/STAT3 signaling and inhibits glioblastoma cell line growth and migration. Experimental Cell Research 2012; 318(8) doi: 10.1016/j.yexcr.2012.02.017
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Srinivas Reddy Boreddy, Sanjay K. Srivastava. Pancreatic cancer chemoprevention by phytochemicals. Cancer Letters 2013; 334(1) doi: 10.1016/j.canlet.2012.10.020
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Pushpendra Singh, Felix Bast. High-throughput virtual screening, identification and in vitro biological evaluation of novel inhibitors of signal transducer and activator of transcription 3. Medicinal Chemistry Research 2015; 24(6) doi: 10.1007/s00044-015-1328-6
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Sahil Arora, Gaurav Joshi, Anuhar Chaturvedi, Michael Heuser, Santoshkumar Patil, Raj Kumar. A Perspective on Medicinal Chemistry Approaches for Targeting Pyruvate Kinase M2. Journal of Medicinal Chemistry 2022; 65(2) doi: 10.1021/acs.jmedchem.1c00981
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Subhadas Chatterjee, Sankhadip Bose, Satarupa Acharjee, Anindita Kundu, Sharad Kumar Tripathi, Vicenç Ruiz de Porras, Shweta S. Zinzuwadia, Anupam Bishayee. Oncopreventive and Oncotherapeutic Potential of Plant Secondary Metabolites Against Gastric Cancer: A Review. Phytotherapy Research 2026; 40(3) doi: 10.1002/ptr.70202
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Qiang Wei, Yi-han Zhang. Flavonoids with Anti-Angiogenesis Function in Cancer. Molecules 2024; 29(7) doi: 10.3390/molecules29071570
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Ran Wei, Limin Mao, Ping Xu, Xinghai Zheng, Robert M. Hackman, Gerardo G. Mackenzie, Yuefei Wang. Suppressing glucose metabolism with epigallocatechin-3-gallate (EGCG) reduces breast cancer cell growth in preclinical models. Food & Function 2018; 9(11) doi: 10.1039/C8FO01397G
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Laura Masuelli, Monica Benvenuto, Chiara Focaccetti, Sara Ciuffa, Sara Fazi, Arianna Bei, Martino Tony Miele, Lucia Piredda, Vittorio Manzari, Andrea Modesti, Roberto Bei. Targeting the tumor immune microenvironment with “nutraceuticals”: From bench to clinical trials. Pharmacology & Therapeutics 2021; 219 doi: 10.1016/j.pharmthera.2020.107700
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Li He, Erying Zhang, Jingli Shi, Xiangyong Li, Keyuan Zhou, Qunzhou Zhang, Anh D. Le, Xudong Tang. (−)-Epigallocatechin-3-gallate inhibits human papillomavirus (HPV)-16 oncoprotein-induced angiogenesis in non-small cell lung cancer cells by targeting HIF-1α. Cancer Chemotherapy and Pharmacology 2013; 71(3) doi: 10.1007/s00280-012-2063-z
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