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Oct 28, 2007 (publication date) through Feb 18, 2025
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World Journal of Gastroenterology
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1007-9327
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| For: | Lah JJ, Cui W, Hu KQ. Effects and mechanisms of silibinin on human hepatoma cell lines. World J Gastroenterol 2007; 13(40): 5299-5305 [PMID: 17879397 DOI: 10.3748/wjg.v13.i40.5299] |
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| URL: | https://www.wjgnet.com/1007-9327/full/v13/i40/5299.htm |
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| 1 |
Hsiang-Chun Lai, Hung-Jen Lin, Long-Bin Jeng, Sheng-Teng Huang. Roles of conventional and complementary therapies in recurrent hepatocellular carcinoma. World Journal of Gastrointestinal Oncology 2023; 15(1): 19-35 doi: 10.4251/wjgo.v15.i1.19
|
| 2 |
Farah Abid, Muhammad Saleem, Saleha Yasir, Shumila Arshad, Sundus Qureshi, Mayyda Asif Bajwa, Sana Ashiq, Samreen Tanveer, Mehiwh Qayyum, Kanwal Ashiq. CANCER EPIGENETICS AND THE ROLE OF DIETARY ELEMENTS. Gomal Journal of Medical Sciences 2020; 17(3): 96 doi: 10.46903/gjms/17.03.2070
|
| 3 |
Jian He, Zhengxing Chen, Yao Gu, Ya'nan Li, Ren Wang, Yuan Gao, Wei Feng, Tao Wang. Hydrophilic co-assemblies of two hydrophobic biomolecules improving the bioavailability of silybin. Food & Function 2020; 11(12): 10828 doi: 10.1039/D0FO01882A
|
| 4 |
Katharina L. Hupa, Elmar Jaeckel, Michael P. Manns. Silymarin for Treatment of Nonalcoholic Steatohepatitis–A New Kid on the Block?. Clinical Gastroenterology and Hepatology 2017; 15(12): 1863 doi: 10.1016/j.cgh.2017.08.005
|
| 5 |
G. Ramakrishnan, L. Lo Muzio, C. M. Elinos‐Báez, S. Jagan, T. A. Augustine, S. Kamaraj, P. Anandakumar, T. Devaki. Silymarin inhibited proliferation and induced apoptosis in hepatic cancer cells. Cell Proliferation 2009; 42(2): 229 doi: 10.1111/j.1365-2184.2008.00581.x
|
| 6 |
Chen-Yi Liao, Ching-Chang Lee, Chi-chang Tsai, Chao-Wen Hsueh, Chih-Chiang Wang, I-Hung Chen, Ming-Kai Tsai, Mei-Yu Liu, An-Tie Hsieh, Kuan-Jen Su, Hau-Ming Wu, Shih-Chung Huang, Yi-Chen Wang, Chien-Yao Wang, Shu-Fang Huang, Yen-Cheng Yeh, Ren-Jy Ben, Shang-Tao Chien, Chin-Wen Hsu, Wu-Hsien Kuo. Novel Investigations of Flavonoids as Chemopreventive Agents for Hepatocellular Carcinoma. BioMed Research International 2015; 2015: 1 doi: 10.1155/2015/840542
|
| 7 |
Aalok Basu, Thanaphon Namporn, Pakatip Ruenraroengsak. Critical Review in Designing Plant-Based Anticancer Nanoparticles against Hepatocellular Carcinoma. Pharmaceutics 2023; 15(6): 1611 doi: 10.3390/pharmaceutics15061611
|
| 8 |
Alisa Bahar Beydogan, Sema Bolkent. The effects of silibin administration for different time periods on mouse liver with Ehrlich ascites carcinoma. Pharmacological Reports 2016; 68(3): 543 doi: 10.1016/j.pharep.2015.12.003
|
| 9 |
Alessandro Federico, Marcello Dallio, Carmelina Loguercio. Silymarin/Silybin and Chronic Liver Disease: A Marriage of Many Years. Molecules 2017; 22(2): 191 doi: 10.3390/molecules22020191
|
| 10 |
Alexander Link, Francesc Balaguer, Ajay Goel. Cancer chemoprevention by dietary polyphenols: Promising role for epigenetics. Biochemical Pharmacology 2010; 80(12): 1771 doi: 10.1016/j.bcp.2010.06.036
|
| 11 |
Elizabeth Brandon-Warner, James A. Sugg, Laura W. Schrum, Iain H. McKillop. Silibinin inhibits ethanol metabolism and ethanol-dependent cell proliferation in an in vitro model of hepatocellular carcinoma. Cancer Letters 2010; 291(1): 120 doi: 10.1016/j.canlet.2009.10.004
|
| 12 |
Shengyu Xu, Xiaojun Jiang, Yalei Liu, Xuemei Jiang, Lianqiang Che, Yan Lin, Yong Zhuo, Bin Feng, Zhengfeng Fang, Lun Hua, Jian Li, Jianping Wang, Zhihua Ren, Mengmeng Sun, De Wu. Silibinin Alleviates Lipopolysaccharide Induced Inflammation in Porcine Mammary Epithelial Cells via mTOR/NF‐κB Signaling Pathway. Molecular Nutrition & Food Research 2023; 67(14) doi: 10.1002/mnfr.202200715
|
| 13 |
Gagan Deep, Rajesh Agarwal. Antimetastatic efficacy of silibinin: molecular mechanisms and therapeutic potential against cancer. Cancer and Metastasis Reviews 2010; 29(3): 447 doi: 10.1007/s10555-010-9237-0
|
| 14 |
Vlad Dionisie, Simona Clichici, Rodica M. Ion, Oana O. Danila, Remus Moldovan, Nicoleta Decea, Dan Gheban, Florin Catalin Olteanu, Gabriela A. Filip. In vivosilymarin’s antioxidant and anti-apoptotic effects on photodynamic therapy’s responsiveness. Journal of Porphyrins and Phthalocyanines 2017; 21(03): 189 doi: 10.1142/S1088424617500304
|
| 15 |
Afrodite Betsou, Maria Lambropoulou, Anastasia-Eirini Georgakopoulou, Nikolaos Kostomitsopoulos, Ourania Konstandi, Konstantinos Anagnostopoulos, Christos Tsalikidis, Constantinos E Simopoulos, Georgia Valsami, Alexandra K Tsaroucha. The hepatoprotective effect of silibinin after hepatic ischemia/reperfusion in a rat model is confirmed by immunohistochemistry and qRT-PCR. Journal of Pharmacy and Pharmacology 2021; 73(9): 1274 doi: 10.1093/jpp/rgab062
|
| 16 |
Michal Selc, Radka Macova, Andrea Babelova. Novel Strategies Enhancing Bioavailability and Therapeutical Potential of Silibinin for Treatment of Liver Disorders. Drug Design, Development and Therapy 2024; : 4629 doi: 10.2147/DDDT.S483140
|
| 17 |
Shadia A. Elsayed, Shane Harrypersad, Heba A. Sahyon, Mohammed Abu El-Magd, Charles J. Walsby. Ruthenium(II)/(III) DMSO-Based Complexes of 2-Aminophenyl Benzimidazole with In Vitro and In Vivo Anticancer Activity. Molecules 2020; 25(18): 4284 doi: 10.3390/molecules25184284
|
| 18 |
Xuanbin Wang, Ning Wang, Fan Cheung, Lixing Lao, Charlie Li, Yibin Feng. Chinese medicines for prevention and treatment of human hepatocellular carcinoma: current progress on pharmacological actions and mechanisms. Journal of Integrative Medicine 2015; 13(3): 142 doi: 10.1016/S2095-4964(15)60171-6
|
| 19 |
Yan Wang, Wenmin Yang, Yuan Yang, Xingning Liu, Lanfen Peng, Qi Huang, Kongli Fan, Rui Hu, Jinyu Yi, Xin Zhong, Jing Li, Jialing Sun, Xiaozhou Zhou. Evidence construction of Silibinin capsules against alcoholic liver disease based on a meta-analysis and systematic review. Frontiers in Pharmacology 2025; 16 doi: 10.3389/fphar.2025.1516204
|
| 20 |
Reza Ghasemi, Seyed H. Ghaffari, Majid Momeny, Saeed Pirouzpanah, Mehdi Yousefi, Mohsen Malehmir, Kamran Alimoghaddam, Ardeshir Ghavamzadeh. Multitargeting and Antimetastatic Potentials of Silibinin in Human HepG-2 and PLC/PRF/5 Hepatoma Cells. Nutrition and Cancer 2013; 65(4): 590 doi: 10.1080/01635581.2013.770043
|
| 21 |
Mahdi Mashhadi Akbar Boojar, Massoud Mashhadi Akbar Boojar, Sepide Golmohammad. Overview of Silibinin anti-tumor effects. Journal of Herbal Medicine 2020; 23: 100375 doi: 10.1016/j.hermed.2020.100375
|
| 22 |
S. Maya, M. Sabitha, Shantikumar V. Nair, R. Jayakumar. Multifaceted Development and Application of Biopolymers for Biology, Biomedicine and Nanotechnology. Advances in Polymer Science 2012; 254: 203 doi: 10.1007/12_2012_195
|
| 23 |
E Yurtcu, ÖD İşeri, FI Sahin. Genotoxic and cytotoxic effects of doxorubicin and silymarin on human hepatocellular carcinoma cells. Human & Experimental Toxicology 2014; 33(12): 1269 doi: 10.1177/0960327114529453
|
| 24 |
Rabea Parveen, Naveen Reddy Penumallu, Sayeed Ahmad. Nanotechnology Principles in Drug Targeting and Diagnosis. 2023; : 173 doi: 10.1016/B978-0-323-91763-6.00016-3
|
| 25 |
Liang-hua Fang, Shen-lin Liu, Rui-ping Wang, Shou-you Hu, Wen-zheng Ju, Chang-yin Li. Tounong Powder (透脓散) extracts induce G1 cell cycle arrest and apoptosis in LoVo cells. Chinese Journal of Integrative Medicine 2016; doi: 10.1007/s11655-016-2597-8
|
| 26 |
Yangyang Hu, Shengpeng Wang, Xu Wu, Jinming Zhang, Ruie Chen, Meiwan Chen, Yitao Wang. Chinese herbal medicine-derived compounds for cancer therapy: A focus on hepatocellular carcinoma. Journal of Ethnopharmacology 2013; 149(3): 601 doi: 10.1016/j.jep.2013.07.030
|
| 27 |
Harold Ting, Gagan Deep, Rajesh Agarwal. Molecular Mechanisms of Silibinin-Mediated Cancer Chemoprevention with Major Emphasis on Prostate Cancer. The AAPS Journal 2013; 15(3): 707 doi: 10.1208/s12248-013-9486-2
|
| 28 |
Ha Ra Gu, Su Cheol Park, Su Jin Choi, Jae Cheol Lee, You Cheoul Kim, Chul Ju Han, Jin Kim, Ki Young Yang, Yeon Joo Kim, Geum Youb Noh, So Hyeon No, Jae-Hoon Jeong. Combined treatment with silibinin and either sorafenib or gefitinib enhances their growth-inhibiting effects in hepatocellular carcinoma cells. Clinical and Molecular Hepatology 2015; 21(1): 49 doi: 10.3350/cmh.2015.21.1.49
|
| 29 |
Abdulrahman Hatawsh, Roya Hadi Al-Haddad, Ukamaka Gladys Okafor, Lamis M. Diab, Nino Dekanoidze, Adeniyi Ayinde Abdulwahab, Osama A. Mohammed, Ahmed S. Doghish, Rewan Moussa, Hanan Elimam. Mitoepigenetics pathways and natural compounds: a dual approach to combatting hepatocellular carcinoma. Medical Oncology 2024; 41(12) doi: 10.1007/s12032-024-02538-8
|
| 30 |
Erika Ramos-Tovar, Pablo Muriel. Dietary Interventions in Liver Disease. 2019; : 101 doi: 10.1016/B978-0-12-814466-4.00009-4
|
| 31 |
Vahab Ghalehkhondabi, Meysam Soleymani, Alireza Fazlali. Folate-targeted nanomicelles containing silibinin as an active drug delivery system for liver cancer therapy. Journal of Drug Delivery Science and Technology 2021; 61: 102157 doi: 10.1016/j.jddst.2020.102157
|
| 32 |
Ajay Goel, Gaurav Chaturvedi. Nutrition, Diet and Cancer. 2012; : 283 doi: 10.1007/978-94-007-2923-0_13
|
| 33 |
Jun-ichi Okano, Yuki Fujise, Ryo Abe, Ryu Imamoto, Yoshikazu Murawaki. Chemoprevention against hepatocellular carcinoma. Clinical Journal of Gastroenterology 2011; 4(4): 185 doi: 10.1007/s12328-011-0227-8
|
| 34 |
Chin-Hui Su, Li-Jen Chen, Jyh Fei Liao, Juei-Tang Cheng. Increase of Phosphatase and Tensin Homolog by Silymarin to Inhibit Human Pharynx Squamous Cancer. Journal of Medicinal Food 2013; 16(9): 778 doi: 10.1089/jmf.2012.2534
|
| 35 |
Kylie O’Brien, Avni Sali. A Clinician's Guide to Integrative Oncology. 2017; : 231 doi: 10.1007/978-3-319-56632-0_7
|
| 36 |
Yong-Hong Xu, Li-Jie Zhao, Yan Li. Alisol B acetate induces apoptosis of SGC7901 cells <italic>via</italic> mitochondrial and phosphatidylinositol 3-kinases/Akt signaling pathways. World Journal of Gastroenterology 2009; 15(23): 2870-2877 doi: 10.3748/wjg.15.2870
|
| 37 |
Nour Y.S. Yassin, Sameh F. AbouZid, Asmaa M. El-Kalaawy, Tarek M. Ali, Mazen M. Almehmadi, Osama M. Ahmed. Silybum marianum total extract, silymarin and silibinin abate hepatocarcinogenesis and hepatocellular carcinoma growth via modulation of the HGF/c-Met, Wnt/β-catenin, and PI3K/Akt/mTOR signaling pathways. Biomedicine & Pharmacotherapy 2022; 145: 112409 doi: 10.1016/j.biopha.2021.112409
|
| 38 |
J. Arellanes-Robledo, C. Hernández, J. Camacho, J.I. Pérez-Carreón. Liver Pathophysiology. 2017; : 563 doi: 10.1016/B978-0-12-804274-8.00042-4
|
| 39 |
Ioannis Anestopoulos, Georgia Persephoni Voulgaridou, Alexandros G. Georgakilas, Rodrigo Franco, Aglaia Pappa, Mihalis I. Panayiotidis. Epigenetic therapy as a novel approach in hepatocellular carcinoma. Pharmacology & Therapeutics 2015; 145: 103 doi: 10.1016/j.pharmthera.2014.09.005
|
| 40 |
Hong-jun Wang, Shin-ichi Tashiro, Satoshi Onodera, Takashi Ikejima. Inhibition of Insulin-like Growth Factor 1 Receptor Signaling Enhanced Silibinin-Induced Activation of Death Receptor and Mitochondrial Apoptotic Pathways in Human Breast Cancer MCF-7 Cells. Journal of Pharmacological Sciences 2008; 107(3): 260 doi: 10.1254/jphs.08054FP
|
| 41 |
Mohamed El-Far, Neven Salah, Alaa Essam, Amira O Abd El-Azim, Ibrahim M El-Sherbiny. Silymarin Nanoformulation as Potential Anticancer Agent in Experimental Ehrlich Ascites Carcinoma-Bearing Animals. Nanomedicine 2018; 13(15): 1865 doi: 10.2217/nnm-2017-0394
|
| 42 |
Bui Thanh Tung, Dang Kim Ngan, Do Thi Hong Khanh. Handbook of Research on Natural Products and Their Bioactive Compounds as Cancer Therapeutics. Advances in Medical Diagnosis, Treatment, and Care 2022; : 232 doi: 10.4018/978-1-7998-9258-8.ch011
|
| 43 |
Wei Cui, Fan Gu, Ke-Qin Hu. Effects and mechanisms of silibinin on human hepatocellular carcinoma xenografts in nude mice. World Journal of Gastroenterology 2009; 15(16): 1943-1950 doi: 10.3748/wjg.15.1943
|
| 44 |
Christian Busch, Markus Burkard, Christian Leischner, Ulrich M. Lauer, Jan Frank, Sascha Venturelli. Epigenetic activities of flavonoids in the prevention and treatment of cancer. Clinical Epigenetics 2015; 7(1) doi: 10.1186/s13148-015-0095-z
|
| 45 |
Cheng-Chia Tsai, Tang-Wei Chuang, Li-Jen Chen, Ho-Shan Niu, Kun-Ming Chung, Juei-Tang Cheng, Kao-Chang Lin. Increase in apoptosis by combination of metformin with silibinin in human colorectal cancer cells. World Journal of Gastroenterology 2015; 21(14): 4169-4177 doi: 10.3748/wjg.v21.i14.4169
|
| 46 |
Xing-Xing Zhu, Ya-Hui Ding, Yi Wu, Lin-Yan Qian, Hai Zou, Qiang He. Silibinin: a potential old drug for cancer therapy. Expert Review of Clinical Pharmacology 2016; 9(10): 1323 doi: 10.1080/17512433.2016.1208563
|
| 47 |
István-Péter Laszló, Mihaela Ramona Laszló, Vlad Toma, Ioana Baldea, Diana Olteanu, Luminita David, Bianca Moldovan, Rodica Mariana Ion, Remus Moldovan, Gabriela Adriana Filip, Gabriel Kacso, Calin Cainap, Simona Clichici, Adriana Muresan. The in vivo modulatory effects of Cornus mas extract on photodynamic therapy in experimental tumors. Photodiagnosis and Photodynamic Therapy 2020; 30: 101656 doi: 10.1016/j.pdpdt.2020.101656
|
| 48 |
Priyanka Sekar, Raashmi Ravitchandirane, Sofia Khanam, Nethaji Muniraj, Ananda Vayaravel Cassinadane. Novel molecules as the emerging trends in cancer treatment: an update. Medical Oncology 2022; 39(2) doi: 10.1007/s12032-021-01615-6
|
| 49 |
|
| 50 |
Hann‐Chin Yu, Li‐Jen Chen, Kai‐Chun Cheng, Ying‐Xiao Li, Ching‐Hua Yeh, Juei‐Tang Cheng. Silymarin Inhibits Cervical Cancer Cell Through an Increase of Phosphatase and Tensin Homolog. Phytotherapy Research 2012; 26(5): 709 doi: 10.1002/ptr.3618
|
| 51 |
Lidia Radko, Wojciech Cybulski, Wojciech Rzeski. The Protective Effect of Silybin against Lasalocid Cytotoxic Exposure on Chicken and Rat Cell Lines. BioMed Research International 2013; 2013: 1 doi: 10.1155/2013/783519
|
| 52 |
Heike K. Winter, Veronika A. Ehrlich, Michael Grusch, Andreas Lackner, Rolf Schulte-Hermann, Bettina Grasl-Kraupp, Wolfgang Mikulits, Siegfried Knasmüller. Use of four new human-derived liver-cell lines for the detection of genotoxic compounds in the single-cell gel electrophoresis (SCGE) assay. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 2008; 657(2): 133 doi: 10.1016/j.mrgentox.2008.08.012
|
| 53 |
Jasmine Baby, Aswathy R. Devan, Ayana R. Kumar, Jaggaiah N. Gorantla, Bhagyalakshmi Nair, Thanatharayil Sathian Aishwarya, Lekshmi R. Nath. Cogent role of flavonoids as key orchestrators of chemoprevention of hepatocellular carcinoma: A review. Journal of Food Biochemistry 2021; 45(7) doi: 10.1111/jfbc.13761
|
| 54 |
P García-Maceira, J Mateo. Silibinin inhibits hypoxia-inducible factor-1α and mTOR/p70S6K/4E-BP1 signalling pathway in human cervical and hepatoma cancer cells: implications for anticancer therapy. Oncogene 2009; 28(3): 313 doi: 10.1038/onc.2008.398
|
| 55 |
Deniz Şumnulu. Contrary to known silibinin is not an anticancer agent and liver protective supplement. Genetika 2023; 55(2): 553 doi: 10.2298/GENSR2302553S
|
| 56 |
Ioannis Anestopoulos, Aristeidis Sfakianos, Rodrigo Franco, Katerina Chlichlia, Mihalis Panayiotidis, David Kroll, Aglaia Pappa. A Novel Role of Silibinin as a Putative Epigenetic Modulator in Human Prostate Carcinoma. Molecules 2016; 22(1): 62 doi: 10.3390/molecules22010062
|
| 57 |
Zu-Yau Lin, Wan-Long Chuang. Influence of silibinin on differential expressions of total cytokine genes in human hepatocellular carcinoma cell lines. Biomedicine & Preventive Nutrition 2011; 1(2): 91 doi: 10.1016/j.bionut.2011.02.002
|
| 58 |
Kumaraguruparan Ramasamy, Rajesh Agarwal. Multitargeted therapy of cancer by silymarin. Cancer Letters 2008; 269(2): 352 doi: 10.1016/j.canlet.2008.03.053
|
| 59 |
L. Radko, W. Cybulski, W. Rzeski. Cytoprotective effect of silybin against lasalocid-induced toxicity in HepG2 cells. Polish Journal of Veterinary Sciences 2013; 16(2): 275 doi: 10.2478/pjvs-2013-0038
|
| 60 |
Aakash Deep, Davinder Kumar, Nitin Bansal, Balasubramanian Narasimhan, Rakesh Kumar Marwaha, Prabodh Chander Sharma. Understanding mechanistic aspects and therapeutic potential of natural substances as anticancer agents. Phytomedicine Plus 2023; 3(2): 100418 doi: 10.1016/j.phyplu.2023.100418
|
| 61 |
Majid Momeny, Mohammad R. Khorramizadeh, Seyed H. Ghaffari, Mehdi Yousefi, Mir S. Yekaninejad, Rezvan Esmaeili, Zahra Jahanshiri, Mohammad R. Nooridaloii. Effects of silibinin on cell growth and invasive properties of a human hepatocellular carcinoma cell line, HepG-2, through inhibition of extracellular signal-regulated kinase 1/2 phosphorylation. European Journal of Pharmacology 2008; 591(1-3): 13 doi: 10.1016/j.ejphar.2008.06.011
|
| 62 |
Ming-Rong Cao, Qiang Li, Zhi-Long Liu, Hui-Hui Liu, Wei Wang, Xiao-Li Liao, Yun-Long Pan, Jian-Wei Jiang. Harmine induces apoptosis in HepG2 cells via mitochondrial signaling pathway. Hepatobiliary & Pancreatic Diseases International 2011; 10(6): 599 doi: 10.1016/S1499-3872(11)60102-1
|
| 63 |
Zohreh Jahanafrooz, Nasrin Motamed, Beate Rinner, Ahad Mokhtarzadeh, Behzad Baradaran. Silibinin to improve cancer therapeutic, as an apoptotic inducer, autophagy modulator, cell cycle inhibitor, and microRNAs regulator. Life Sciences 2018; 213: 236 doi: 10.1016/j.lfs.2018.10.009
|
| 64 |
Wen-Shiung Liou, Li-Jen Chen, Ho-Shan Niu, Ting-Ting Yang, Juei-Tang Cheng, Kao-Chang Lin. Herbal product silibinin-induced programmed cell death is enhanced by metformin in cervical cancer cells at the dose without influence on nonmalignant cells. Journal of Applied Biomedicine 2015; 13(2): 113 doi: 10.1016/j.jab.2014.11.001
|
| 65 |
Jeanetta K. Mastron, Kodappully S. Siveen, Gautam Sethi, Anupam Bishayee. Silymarin and hepatocellular carcinoma. Anti-Cancer Drugs 2015; 26(5): 475 doi: 10.1097/CAD.0000000000000211
|
| 66 |
Lorenzo Di Cesare Mannelli, Matteo Zanardelli, Paola Failli, Carla Ghelardini. Oxaliplatin-Induced Neuropathy: Oxidative Stress as Pathological Mechanism. Protective Effect of Silibinin. The Journal of Pain 2012; 13(3): 276 doi: 10.1016/j.jpain.2011.11.009
|
| 67 |
Navaneethakrishnan Polachi, Guirong Bai, Tingyang Li, Yang Chu, Xiangyang Wang, Shuming Li, Ning Gu, Jiang Wu, Wei Li, Yanjun Zhang, Shuiping Zhou, He Sun, Changxiao Liu. Modulatory effects of silibinin in various cell signaling pathways against liver disorders and cancer – A comprehensive review. European Journal of Medicinal Chemistry 2016; 123: 577 doi: 10.1016/j.ejmech.2016.07.070
|
| 68 |
Jijiao Wu, Lin Wen, Xiaolian Liu, Qiuxia Li, Zihao Sun, Chuipeng Liang, Fan Xie, Xiaofang Li. Silybin: A Review of Its Targeted and Novel Agents for Treating Liver Diseases Based on Pathogenesis. Phytotherapy Research 2024; 38(12): 5713 doi: 10.1002/ptr.8347
|
| 69 |
Kai-Chun Cheng, Akihiro Asakawa, Ying-Xiao Li, Hsien-Hui Chung, Haruka Amitani, Takatoshi Ueki, Juei-Tang Cheng, Akio Inui, Marcia B. Aguila. Silymarin Induces Insulin Resistance through an Increase of Phosphatase and Tensin Homolog in Wistar Rats. PLoS ONE 2014; 9(1): e84550 doi: 10.1371/journal.pone.0084550
|
| 70 |
Monica Foghis, Simona Gabriela Bungau, Alexa Florina Bungau, Cosmin Mihai Vesa, Anamaria Lavinia Purza, Alexandra Georgiana Tarce, Delia Mirela Tit, Annamaria Pallag, Tapan Behl, Syed Shams ul Hassan, Andrei-Flavius Radu. Plants-based medicine implication in the evolution of chronic liver diseases. Biomedicine & Pharmacotherapy 2023; 158: 114207 doi: 10.1016/j.biopha.2022.114207
|
| 71 |
Yan Li, Robert C. G. Martin. Herbal Medicine and Hepatocellular Carcinoma: Applications and Challenges. Evidence-Based Complementary and Alternative Medicine 2011; 2011(1) doi: 10.1093/ecam/neq044
|
| 72 |
Bao-Xia Li, Heng-Bang Wang, Miao-Zhen Qiu, Qiu-Yun Luo, Han-Jie Yi, Xiang-Lei Yan, Wen-Tao Pan, Lu-Ping Yuan, Yu-Xin Zhang, Jian-Hua Xu, Lin Zhang, Da-Jun Yang. Novel smac mimetic APG-1387 elicits ovarian cancer cell killing through TNF-alpha, Ripoptosome and autophagy mediated cell death pathway. Journal of Experimental & Clinical Cancer Research 2018; 37(1) doi: 10.1186/s13046-018-0703-9
|
| 73 |
Hayder Gaeed Oufi, Nada Naji Al-Shawi. The effects of different doses of silibinin in combination with methotrexate on testicular tissue of mice. European Journal of Pharmacology 2014; 730: 36 doi: 10.1016/j.ejphar.2014.02.010
|
| 74 |
dilek bayram. Silibinin İn Vitro Ortamda CCL-228-SW 480 Kolon Kanseri Hücre Hattı Üzerine Apoptotik Etkisinin Araştırılması. SDÜ Sağlık Bilimleri Dergisi 2017; : 1 doi: 10.22312/sdusbed.287465
|
| 75 |
Hu Xiangbing, Zhang Yankai, Lin Ming, Lu Yong, Zhang Yu, Zhang Huiyong, Chen Yingying, Hou Jing, Xing Yun, Jin Liang, Cao Rongyue, Liu Jingjing. The fusion protein of HSP65 with tandem repeats of β-hCG acting as a potent tumor vaccine in suppressing hepatocarcinoma. International Immunopharmacology 2010; 10(2): 230 doi: 10.1016/j.intimp.2009.11.006
|
| 76 |
HENRIETTE KAUNTZ, SOUAD BOUSSEROUEL, FRANCINE GOSSÉ, FRANCIS RAUL. Epigenetic effects of the natural flavonolignan silibinin on colon adenocarcinoma cells and their derived metastatic cells. Oncology Letters 2013; 5(4): 1273 doi: 10.3892/ol.2013.1190
|