Minireviews
Copyright ©2014 Baishideng Publishing Group Inc. All rights reserved.
World J Meta-Anal. May 26, 2014; 2(2): 24-28
Published online May 26, 2014. doi: 10.13105/wjma.v2.i2.24
Prognostic significance of post percutaneous coronary intervention thrombocytopenia
Michele Schiariti, Loredana Iannetta, Concetta Torromeo, Michele De Gregorio, Paolo Emilio Puddu
Michele Schiariti, Loredana Iannetta, Concetta Torromeo, Paolo Emilio Puddu, Laboratory of Biotechnologies Applied to Cardiovascular Medicine, Department of Cardiovascular, Respiratory, Nephrological, Anesthesiological and Geriatrical Sciences, Sapienza University of Rome, 00161 Rome, Italy
Michele De Gregorio, Department of Medicine, St. Joseph Mercy Oakland Hospital, Pontiac, MI 48341, United States
Author contributions: All the authors contributed equally to this work.
Correspondence to: Paolo Emilio Puddu, MD, PhD, FESC, FACC, Laboratory of Biotechnologies Applied to Cardiovascular Medicine, Department of Cardiovascular, Respiratory, Nephrological, Anesthesiological and Geriatrical Sciences, Sapienza University of Rome, Viale del Policlinico, 155, 00161 Rome, Italy. paoloemilio.puddu@uniroma1.it
Telephone: +39-6-49972654 Fax: +39-6-4453891
Received: November 5, 2013
Revised: January 25, 2014
Accepted: February 18, 2014
Published online: May 26, 2014
Processing time: 227 Days and 14.8 Hours
Core Tip

Core tip: This minireview suggested that further investigations are needed to determine whether there is a real link between thrombocytopenia (TC), a probably well defined covariate, and ischemic outcomes or whether intra-aortic balloon (IABP) is the joining link between these two variables and whose presence needs in any case be considered in multivariable statistics. Post-percutaneous coronary intervention TC could be only a secondary effect of IABP use. On turn, the prolonged use of heparin necessarily accompanying the use of IABP, and producing a paradoxical pro-thrombotic TC, might also be implicated.