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©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Meta-Anal. Oct 28, 2022; 10(5): 238-243
Published online Oct 28, 2022. doi: 10.13105/wjma.v10.i5.238
Published online Oct 28, 2022. doi: 10.13105/wjma.v10.i5.238
Maintaining the metabolic homeostasis of Helicobacter pylori through chronic hyperglycemia in diabetes mellitus: A hypothesis
Vasiliy Ivanovich Reshetnyak, Igor Veniaminovich Maev, Department of Propaedeutics of Internal Diseases and Gastroenterology, A.I. Yevdokimov Moscow State University of Medicine and Dentistry, Moscow 127473, Russia
Author contributions: All the authors have equally contributed to the study conception and design, literature review and analysis, manuscript drafting, critical revision and editing, and approval of the final version.
Conflict-of-interest statement: All authors declare that they have no conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Vasiliy Ivanovich Reshetnyak, MD, MDS, PhD, Full Professor, Department of Propaedeutics of Internal Diseases and Gastroenterology, A.I. Yevdokimov Moscow State University of Medicine and Dentistry, 20, Delegatskaya St., Build. 1, Moscow 127473, Russia. vasiliy.reshetnyak@yandex.ru
Received: August 4, 2022
Peer-review started: August 4, 2022
First decision: August 19, 2022
Revised: August 23, 2022
Accepted: September 21, 2022
Article in press: September 21, 2022
Published online: October 28, 2022
Processing time: 84 Days and 20.4 Hours
Peer-review started: August 4, 2022
First decision: August 19, 2022
Revised: August 23, 2022
Accepted: September 21, 2022
Article in press: September 21, 2022
Published online: October 28, 2022
Processing time: 84 Days and 20.4 Hours
Core Tip
Core Tip: The authors hypothesize that in patients with diabetes mellitus (DM), Helicobacter pylori (H. pylori) are most likely to rely on both amino acids and glucose for its vital activity. The hypothesis makes it possible to explain the high detection rate of H. pylori in patients with DM, as well as the lower efficiency of eradication therapy in them.