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World J Meta-Anal. Apr 28, 2022; 10(2): 46-51
Published online Apr 28, 2022. doi: 10.13105/wjma.v10.i2.46
Is there a role for liver transplantation in the treatment of hepatocellular carcinoma in non-cirrhotic liver?
Luis Cesar Bredt, Ingryd Betina Garcia Felisberto, Doroty Eva Garcia Felisberto
Luis Cesar Bredt, Surgical Oncology and Hepatobiliary Surgery, Unioeste University, Cascavel 85819-110, Paraná, Brazil
Ingryd Betina Garcia Felisberto, Internal Medicine, Univates University, Lajeado 95914-014, Rio Grande do Sul, Brazil
Doroty Eva Garcia Felisberto, Department of Surgery, Nossa Senhora das Graças Hospital, Curitiba 80810-040, Paraná, Brazil
Author contributions: All authors contributed equally to this review article; all authors equally contributed to this paper with conception and design of the study, literature review and analysis, drafting and critical revision and editing, and final approval of the final version.
Conflict-of-interest statement: No potential conflicts of interest. No financial support.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Luis Cesar Bredt, FRCS (Hon), PhD, Full Professor, Surgical Oncologist, Surgical Oncology and Hepatobiliary Surgery, Unioeste University, R. Universitária, 2069, Cascavel 85819-110, Paraná, Brazil. lcbredt@gmail.com
Received: December 23, 2021
Peer-review started: December 23, 2021
First decision: March 10, 2022
Revised: March 21, 2022
Accepted: April 28, 2022
Article in press: April 28, 2022
Published online: April 28, 2022
Processing time: 126 Days and 3 Hours
Core Tip

Core Tip: The present manuscript aims to discuss and analyze the last series of liver transplantation for hepatocellular carcinoma in non-cirrhotic liver, with a special focus on the indications, prognostic factors and long-term outcomes, in order to help clinicians in the decision-making regarding the role of liver transplantation in the non-cirrhotic liver –hepatocellular carcinoma scenario on the basis of these analyses.