Meta-Analysis
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Meta-Anal. Apr 28, 2022; 10(2): 63-73
Published online Apr 28, 2022. doi: 10.13105/wjma.v10.i2.63
Effect of auricular plaster for primary hypertension in older people: A meta-analysis
Yong Qin, Yu Lou, Xiao-Yan Shen, Yun Gai
Yong Qin, Yu Lou, Xiao-Yan Shen, Yun Gai, Department of Cardiology, The Seventh People's Hospital of Shanghai University of TCM, Shanghai 200137, China
Yun Gai, Department of General Medicine, The Seventh People's Hospital of Shanghai University of TCM, Shanghai 200137, China
Author contributions: Qin Y, Lou Y, and Gai Y participated in the conception and design of the study, library searches and assembling relevant literature, critical review of the paper, supervising the writing of the paper and database management; Qin Y, Shen XY, and Gai Y participated in data collection, library searches assembling relevant literature, writing the paper and critical review.
Supported by Leading talent training of Pudong New Area Health Committee, No. PWR12020-02; Exploration on the discipline construction mode of treating and preventing diseases based on specific diseases, No. PWZY-2019-0402; Shanghai collaborative innovation center of traditional Chinese medicine health services.
Conflict-of-interest statement: All authors declare that they have no conflict of interest.
PRISMA 2009 Checklist statement: This study was conducted as per PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yun Gai, Chief Physician, Department of General Medicine, The Seventh People's Hospital of Shanghai University of TCM, No. 358 Gaoqiao Datong Road, Shanghai 200137, China. gaiyunlucky@163.com
Received: December 4, 2021
Peer-review started: December 4, 2021
First decision: December 27, 2021
Revised: January 25, 2022
Accepted: April 24, 2022
Article in press: April 24, 2022
Published online: April 28, 2022
Processing time: 145 Days and 5.2 Hours
ARTICLE HIGHLIGHTS
Research background

Hypertension is a very common health problem for older people. Recently, a non-drug therapy called auricular plaster has been used to treat hypertension in China and is considered traditional Chinese medicine. There were many clinical studies which reported on auricular plaster therapy for elderly patients with hypertension but the intervention methods and intervention times were quite different.

Research motivation

We speculate about gaining a detailed insight into the effect of auricular plaster therapy on elderly patients with primary hypertension.

Research objectives

This study aimed to evaluate the effect of auricular plaster therapy combined with western medicine to treat primary hypertension in older people.

Research methods

A literature search was carried out to identify reports published through July 1, 2021. The meta-analysis was carried out for the outcomes of the significant difference in the effective ratio, diastolic blood pressure (DBP) change, systolic blood pressure (SBP) change, and symptom score between auricular plaster combined with western medicine group and western medicine alone group. Publication bias was identified by the funnel plots test.

Research results

In this analysis, fourteen (14) relevant studies were included. The Meta-analysis showed a significant difference in the clinical effective ratio (OR = 3.62; 95%CI, 2.46 to 5.33; P < 0.00001), DBP change (5.68 mmHg; 95%CI, 3.49 to 7.87; P < 0.00001), SBP change (MD = 8.78 mmHg; 95%CI, 5.04 to 12.53; P < 0.00001) and symptom score (MD = 3.20; 95%CI, 1.23 to 5.18; P = 0.001) between auricular plaster combined with western medicine group and western medicine alone group.

Research conclusions

Auricular plaster could be a potential therapy to treat hypertension in elderly patients.

Research perspectives

More prospective sample studies are needed in the future to enhance the speculation of our conclusion.