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Nong XF, Cao X, Tan XL, Jing LY, Liu H. Percheron syndrome with memory impairment as chief manifestation: A case report. World J Clin Cases 2025; 13:98937. [PMID: 40330285 PMCID: PMC11736529 DOI: 10.12998/wjcc.v13.i13.98937] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 07/09/2024] [Revised: 11/14/2024] [Accepted: 12/27/2024] [Indexed: 01/11/2025] Open
Abstract
BACKGROUND Percheron acute artery occlusion is a rare type of acute cerebral infarction. CASE SUMMARY An elderly male presented with sudden-onset near-memory and sensory impairments for 5 days. Upon admission, based on symptoms, signs, magnetic resonance imaging, and computed tomography findings, a diagnosis of Percheron syndrome was made. Subsequently, anti-platelet therapy, lipid-lowering treatment, cerebral circulation enhancement (such as the administration of calcium channel blockers to improve cerebral blood flow), and neurotrophic support (such as the use of drugs like citicoline to protect nerve cells) were immediately implemented, along with additional symptomatic treatments. The patient's symptoms were alleviated, following which he was discharged. CONCLUSION The diagnosis of acute occlusion of the Percheron artery requires rich clinical expertise and accurate imaging tools. Timely intervention and effective follow-up hold significant implications for optimizing patient recovery.
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Affiliation(s)
- Xi-Feng Nong
- Department of Neurology, The Seventh Affiliated Hospital of Southern Medical University, Foshan 528200, Guangdong Province, China
| | - Xiao Cao
- Department of Neurology, The Seventh Affiliated Hospital of Southern Medical University, Foshan 528200, Guangdong Province, China
| | - Xing-Lin Tan
- Department of Neurology, The Seventh Affiliated Hospital of Southern Medical University, Foshan 528200, Guangdong Province, China
| | - Li-Yan Jing
- Department of Neurology, The Seventh Affiliated Hospital of Southern Medical University, Foshan 528200, Guangdong Province, China
| | - Hao Liu
- Department of Cardiology, The Seventh Affiliated Hospital of Southern Medical University, Foshan 528200, Guangdong Province, China
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Jang SH, Lee SJ, Cho MJ. Relationship between consciousness and the thalamocortical tract in patients with intracerebral hemorrhage. Medicine (Baltimore) 2023; 102:e35510. [PMID: 37832068 PMCID: PMC10578689 DOI: 10.1097/md.0000000000035510] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 06/23/2023] [Accepted: 09/14/2023] [Indexed: 10/15/2023] Open
Abstract
In patients with intracerebral hemorrhage (ICH), the relationship between consciousness and the thalamocortical tract (TCT), which links the thalamic intralaminar nuclei (ILN) and the cerebral cortex, was investigated. Forty-one patients with ICH were assigned to 1 of 2 groups according to their preservation of consciousness as determined by their Glasgow coma scale (GCS) score. Patient group A had impaired consciousness (GCS < 15, 21 patients), and patient group B had intact consciousness (GCS = 15, 20 patients). The control group included 20 age- and sex-matched healthy subjects. For all groups, the TCTs from the thalamic ILN of both sides were reconstructed using a probabilistic tractography method based on a multifiber model. In addition, tract volume (TV) values were determined. The TV values for the ipsilateral TCT from the thalamic ILN of the all-patient groups and those for contralateral TCT of the patient group B showed no significant differences between ICH and contra-ICH sides (P > .05). The TV results for the ipsilateral and contralateral TCTs from the thalamic ILN of the ICH and contra-ICH sides were significantly different among the 3 groups (P < .05). Among the patients, there were moderate positive correlations between GCS scores and TV values of the ipsilateral TCT on the ICH and contra-ICH sides (R = 0.477, P < .05; R = 0.426, P < .05). The TV of the ipsilateral TCT from the thalamic ILN on the ICH and contra-ICH sides was significantly correlated with the consciousness level in patients with ICH. Our results could be helpful when developing therapeutic strategies for ICH patients with disorders of consciousness.
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Affiliation(s)
- Sung Ho Jang
- Department of Physical Medicine and Rehabilitation, College of Medicine, Yeungnam University, Namku, Taegu, Republic of Korea
| | - Sung Jun Lee
- Department of Physical Therapy, College of Health Sciences, Dankook University, Dongnamgu, Cheonan, Republic of Korea
| | - Min Jye Cho
- Department of Physical Medicine and Rehabilitation, College of Medicine, Yeungnam University, Namku, Taegu, Republic of Korea
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Li F, Gong Q, Lu Y. Effects of continuous nursing on rehabilitation compliance, living quality and daily living ability of patients with acute ischemic stroke. Am J Transl Res 2022; 14:381-388. [PMID: 35173856 PMCID: PMC8829598] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/06/2021] [Accepted: 11/22/2021] [Indexed: 06/14/2023]
Abstract
OBJECTIVES To investigate the effect of continuous nursing on rehabilitation of patients with acute ischemic stroke (AIS). METHODS In this prospective study, 150 patients were treated for AIS at our hospital from January 2017 to December 2019. The patients were separated into two groups: the conventional group (n = 75) that received conventional nursing and the continuous nursing group (n = 75) were treated with continuous nursing intervention. Patients were followed up for compliance, negative mood, living quality, nursing satisfaction, and daily living abilities. RESULTS The compliance rate of the continuous nursing group (93.33%) was obviously higher than that of the conventional nursing group (85.33%, P<0.05). There was no obvious difference in the negative mood scores between the two groups before intervention (P>0.05); however, the negative mood scores of the two groups decreased after intervention. In particular, the scores in continuous nursing group were obviously lower than that in the conventional nursing group (P<0.05). After intervention, the living quality scores in the continuous nursing group were obviously higher than that in the conventional nursing group (P<0.05). The satisfaction of nurses in the continuous nursing (96.00%) was obviously higher than that in the conventional nursing group (70.00%, P<0.05). The Barthel index (BI) scores in the continuous nursing group were obviously higher than those in the conventional nursing at 1 d, 7 d, and 30 d after intervention (P<0.05). CONCLUSIONS The results demonstrated that continuous nursing can enhance the rehabilitation compliance of patients with AIS, alleviate the negative mood of patients, enhance the living quality and daily living ability of patients.
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Affiliation(s)
- Fang Li
- Department of Rehabilitation Medicine, Jinhua Traditional Chinese Medicine Affiliated Hospital of Zhejiang Chinese Medical UniversityJinhua City 321017, Zhejiang Province, China
| | - Qingmei Gong
- Department of Neurology, The Third Affiliated Hospital of Zhejiang Chinese Medical UniversityHangzhou 310012, Zhejiang, China
| | - Ying Lu
- Department of Cardiopulmonary Rehabilitation, The Third Affiliated Hospital of Zhejiang Chinese Medical UniversityHangzhou 310012, Zhejiang, China
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Al Harrach M, Pretzel P, Groeschel S, Rousseau F, Dhollander T, Hertz-Pannier L, Lefevre J, Chabrier S, Dinomais M. A connectome-based approach to assess motor outcome after neonatal arterial ischemic stroke. Ann Clin Transl Neurol 2021; 8:1024-1037. [PMID: 33787079 PMCID: PMC8108427 DOI: 10.1002/acn3.51292] [Citation(s) in RCA: 4] [Impact Index Per Article: 1.0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/03/2020] [Revised: 12/08/2020] [Accepted: 12/09/2020] [Indexed: 12/22/2022] Open
Abstract
Objective Studies of motor outcome after Neonatal Arterial Ischemic Stroke (NAIS) often rely on lesion mapping using MRI. However, clinical measurements indicate that motor deficit can be different than what would solely be anticipated by the lesion extent and location. Because this may be explained by the cortical disconnections between motor areas due to necrosis following the stroke, the investigation of the motor network can help in the understanding of visual inspection and outcome discrepancy. In this study, we propose to examine the structural connectivity between motor areas in NAIS patients compared to healthy controls in order to define the cortical and subcortical connections that can reflect the motor outcome. Methods Thirty healthy controls and 32 NAIS patients with and without Cerebral Palsy (CP) underwent MRI acquisition and manual assessment. The connectome of all participants was obtained from T1‐weighted and diffusion‐weighted imaging. Results Significant disconnections in the lesioned and contra‐lesioned hemispheres of patients were found. Furthermore, significant correlations were detected between the structural connectivity metric of specific motor areas and manuality assessed by the Box and Block Test (BBT) scores in patients. Interpretation Using the connectivity measures of these links, the BBT score can be estimated using a multiple linear regression model. In addition, the presence or not of CP can also be predicted using the KNN classification algorithm. According to our results, the structural connectome can be an asset in the estimation of gross manual dexterity and can help uncover structural changes between brain regions related to NAIS.
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Affiliation(s)
- Mariam Al Harrach
- Université d'Angers, Laboratoire Angevin de Recherche en Ingénierie des Systèmes (LARIS) EA7315, Angers, 49000, France.,Université de Rennes 1, Laboratoire Traitement du Signal et de l'Image (LTSI), INSERM U1099, Rennes, F-35000, France
| | - Pablo Pretzel
- Experimental Paediatric Neuroimaging, Department of Child Neurology, University Hospital Tübingen, Tübingen, Germany
| | - Samuel Groeschel
- Experimental Paediatric Neuroimaging, Department of Child Neurology, University Hospital Tübingen, Tübingen, Germany
| | | | - Thijs Dhollander
- Developmental Imaging, Murdoch Children's Research Institute, Melbourne, Australia
| | - Lucie Hertz-Pannier
- UNIACT, Neurospin, Institut Joliot, CEA-Paris Saclay, Inserm U114, Université de Paris, Gif sur Yvette, F-91191, France
| | - Julien Lefevre
- Institut de Neurosciences de la Timone, UMR 7289, Aix Marseille Université, CNRS, Marseille, 13385, France
| | - Stéphane Chabrier
- INSERM, UMR1059 Sainbiose, Univ Saint-Étienne, Univ Lyon, Saint-Étienne, F-42023, France.,Paediatric Physical and Rehabilitation Medicine Department, CHU Saint-Étienne, French Centre for Paediatric Stroke, INSERM, CIC 1408, Saint-Étienne, F-42055, France
| | - Mickael Dinomais
- Université d'Angers, Laboratoire Angevin de Recherche en Ingénierie des Systèmes (LARIS) EA7315, Angers, 49000, France.,Département de Médecine Physique et de Réadaptions and LUNAM, CHU Angers, Angers, France
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