• anemia
• angiolipoma
• gastrointestinal neoplasms
• hematochezia
• lapraocopic hemicolectomy

• abdominal pain
• acute appendicitis
• angiolipoma
• case report
• laparoscopy
• lipoma

Angiolipomas are benign mesenchymal tumors that often occur under the skin of the upper extremity or thoracic and abdominal walls. Angiolipomas of the digestive tract are rare. Here, we describe a case of transverse colon angiolipoma with intussusception resected by laparoscopy-assisted surgery. A 50-year-old woman visited a family hospital with complaints of left lower abdominal pain and bloody stool. Colonoscopy revealed a submucosal tumor in her left colon. She was referred to our hospital for further examination. Computed tomography revealed a low-density tumor with intussusception in the left transverse colon. Elective surgery was planned for this patient because there were no alarming symptoms such as ileus or obstruction. Laparoscopy-assisted surgery and partial resection of the left transverse colon were performed. The histopathological diagnosis was angiolipoma of the colon. Angiolipomas are benign mesenchymal tumors that rarely occur in the digestive tract. Thus, accurate preoperative diagnosis is difficult.

Angiolipoma is a benign tumor that rarely occurs in the gastrointestinal (GI) tract. This case series was performed to increase clinicians’ understanding of the diagnosis and management of GI angiolipoma.

We evaluated the clinical presentations, diagnoses, and treatments of 3 patients with angiolipoma in the upper GI tract in our hospital and 27 cases reported in the literature.

Among all 30 cases of GI angiolipoma, 2 originated in the esophagus, 4 in the stomach, 2 in the duodenum, 1 in the jejunum, 7 in the ileum, 1 in the cecum, 9 in the colon, 2 in the rectum, and 2 in both the duodenum and colon.

Angiolipoma of the GI tract may be more likely to occur in middle-aged and elderly men and be located in the ileum and colon. The clinical manifestations generally involve upper GI hemorrhage and lower GI pain and obstruction. Computed tomography and endoscopy may be effective diagnostic techniques, but postoperative histopathologic examination is still the gold standard. The management of angiolipoma in the GI tract depends on the size and type of lesion. Most cases in the present series were managed by complete surgical resection, after which no recurrence was found.

• Angiolipoma
• benign tumor
• case series
• complete resection
• gastrointestinal tract
• histopathology

• Aged
• Angiolipoma/diagnostic imaging
• Angiolipoma/surgery
• Endoscopy
• Gastrointestinal Hemorrhage/diagnostic imaging
• Gastrointestinal Tract
• Humans
• Male
• Middle Aged
• Neoplasm Recurrence, Local

• Beijing Municipal Science and Technology Commission
• Chinese Society of Clinical Oncology

Angiolipoma in the region of the hypopharynx-esophageal introitus is a rare occurrence. Surgical treatment was performed in the few cases reported in the literature. Endoscopic submucosal dissection (ESD) is a minimally invasive treatment for hypopharyngeal and esophageal lesions. Our objective was to evaluate the feasibility, safety, and efficacy of ESD for treatment of angiolipoma at the hypopharynx-esophageal introitus. The patients with submucosal tumors at the hypopharynx-esophageal introitus were diagnosed as angiolipoma by preoperative evaluation with endoscopy, endoscopic ultrasonography, and computed tomography (CT). The patients who were diagnosed with angiolipoma agreed to undergo endoscopic submucosal dissection. Under general anesthesia and endotracheal intubation, ESD was used to remove the lesions. Preoperative, intraoperative, and postoperative data were collected and analyzed to evaluate the feasibility, safety, and effectiveness of endoscopic submucosal dissection. From January 2013 to December 2018, 6 cases of angiolipoma were treated with ESD with a success rate of 100%. The average operation time was 107.0 ± 69.4 minutes. Intraoperative blood loss is the main risk. Endoscopic thermocoagulation successfully stopped bleeding in all cases. Pharyngeal pain and painful swallowing were the main clinical signs. There was no stricture at the hypopharynx-esophageal introitus after the operation. ESD treatment of angiolipoma at hypopharynx-esophageal introitus is feasible, safe, and effective.

Angiolipoma is a benign tumor and is generally found in subcutaneous tissues. Angiolipomas are rare in the gastrointestinal tract, including the stomach. Preoperative diagnosis of the tumor is difficult, although there are several radiological examinations such as computed tomography and endoscopic ultrasound.

We report a 24-year-old Chinese man with multiple gastric angiolipomas, with a positive stool occult blood examination. Endoscopic biopsy only showed nonspecific inflammation. Histological examination of the specimen by endoscopic snare resection showed that the tumor consisted of adipose tissues and blood vessels. We also performed a literature review. After the use of proton pump inhibitor, the fecal occult blood test was negative. Due to the difficulty of resecting multiple lesions in the stomach completely and the benign characteristics of angiolipoma, we chose to have regular upper gastrointestinal endoscopy evaluation of the lesion. No evidence of significant change in lesion size was detected after 3-years follow-up.

Gastric angiolipoma is rare, and benign neoplasm should be considered when lesions occur submucosally in the gastrointestinal tract.

• Angiolipoma
• Gastric angiolipoma
• Endoscopic snare resection
• Case report

• gastrointestinal surgery
• general surgery