• Nd:YAG laser
• neurogenic tumor
• tracheal resection and anastomosis
• tracheal schwannoma

• Neurogenic tumor
• schwannoma
• trachea

• Humans
• Neurilemmoma/diagnosis
• Neurilemmoma/diagnostic imaging
• Male
• Asthma/diagnosis
• Asthma/complications
• Tracheal Neoplasms/diagnosis
• Tracheal Neoplasms/diagnostic imaging
• Tracheal Neoplasms/surgery
• Young Adult
• Diagnosis, Differential
• Tomography, X-Ray Computed

• air leaks
• intensive care

• Female
• Humans
• Adolescent
• Mediastinal Emphysema/diagnostic imaging
• Mediastinal Emphysema/etiology
• Mediastinal Emphysema/surgery
• Trachea/diagnostic imaging
• Trachea/surgery
• Trachea/pathology
• Tracheal Neoplasms/diagnosis
• Tracheal Neoplasms/diagnostic imaging
• Neurilemmoma/diagnosis
• Neurilemmoma/diagnostic imaging
• Subcutaneous Emphysema/diagnostic imaging
• Subcutaneous Emphysema/etiology

• neurilemmoma
• neoplasm invasiveness
• trachea
• tracheal neoplasms
• thyroid neoplasms
• thyroidectomy
• differential
• diagnosis

• Humans
• Thyroid Cancer, Papillary
• Trachea/diagnostic imaging
• Trachea/surgery
• Thyroid Neoplasms/diagnostic imaging
• Thyroid Neoplasms/surgery
• Thyroid Neoplasms/pathology
• Tracheal Neoplasms/diagnostic imaging
• Tracheal Neoplasms/surgery
• Tracheal Neoplasms/pathology
• Neurilemmoma/diagnostic imaging
• Neurilemmoma/surgery
• Neurilemmoma/pathology

• resection
• schwannoma
• trachea

• Ablation
• Benign tumor
• Fibroepithelial polyp
• High-frequency electricity
• Tracheal giant polyp

• bronchial schwannoma
• bronchoscopy
• endobronchial lesion
• lung tumor
• spindle cells

• endobronchial tumours
• rigid bronchoscopy
• schwannoma

• Jeju National University

• Tracheobronchial schwannoma
• bronchoscopy
• case report
• cough
• histopathology
• interventional therapy
• nodule

• Benign schwannoma
• Frontal sinus
• Intraparotid facial nerve
• Trachea

Schwannoma is a benign tumor originating from the peripheral nerve sheath. The clinical symptoms of tracheal schwannoma depend on the location of the tumor, and the most common clinical symptoms are cough and hemoptysis. The most effective treatment for benign tumors is complete resection of the primary lesion at an early stage. Our experience has demonstrated that primary tracheal schwannoma can be safely excised with a high-frequency electric knife in a minimally invasive manner.

We report a 61-year-old asymptomatic woman who underwent chest computed tomography (CT), which accidentally found an intraluminal tracheal mass without enlarged lymph nodes. Then, the patient underwent bronchoscopy, which found that the tracheal mass originated from the left wall of the upper trachea, was less than 1.5 cm in size, immovable, smooth and 4 cm away from the vocal cord, resulting in partial upper respiratory tract obstruction. Treatment was performed using an endoscopic resection for en bloc removal of the tracheal mass. The diagnosis was primary tracheal schwannoma. A follow-up was performed after endoscopic surgery, and bronchoscopy and thoracic CT were used to monitor whether there was a recurrence. At present, there is no evidence of recurrence, and the patient had a good quality of life. Endoscopic resection may be effective and safe in the treatment of primary tracheal schwannoma.

Primary tracheal schwannoma is a very rare benign tumor. In this case, we cured it by complete endoscopic resection.

• Schwannoma
• Tracheal tumor
• Endoscopic therapy
• High-frequency electric knife
• En bloc
• Case report

• cervical schwannoma
• conservative treatment
• hot biopsy forceps
• symptomatic asthma
• tracheal stenosis

Primary tracheal schwannoma is a rare disease with no specific symptoms. At the molecular level, neurofibromatosis type 2 (NF2) gene mutation of Schwann cells is the major tumorigenic element. Herein, we present the case of a 54-year-old man with refractory shortness of breath and dry cough, which was resistant to bronchodilator treatment. Computed tomography revealed a transmural mass in the dorsolateral trachea. The tumor was surgically resected, and the diagnosis of schwannoma was confirmed by pathological examination. Furthermore, for this case, we performed whole-exome sequencing and identified several novel mutated schwannoma genes. The specific roles of these mutations need further confirmation.

A 20-year-old male without any prior comorbidities presented with 6-month history of hemoptysis as the sole symptom. Clinico-radiological profile and bronchoscopy were suggestive of a tracheal mass. This clinico-pathologic conference discusses the differential diagnoses of primary tumors of the trachea and their management options.

Tracheal tumors are relatively rare in adults and uncommon in children. Tracheal neurilemmoma is a rare condition in adults that usually affects middle-aged people, but it can also occur in children. Because the clinical presentation is nonspecific and insidious, diagnosis is often delayed. The most common symptoms in these patients are stridor or wheezing (especially positional) and cough. A few patients are misdiagnosed and mistakenly treated for asthma.

A 10-year-old girl was admitted to our unit with a 2-mo history of recurrent cough, dyspnea, and tachypnea. Her condition was more severe after exercise. Her symptoms progressed despite treatment with inhaled fluticasone/salmeterol. Flexible electronic laryngoscopy showed a red, smooth, and round mushroom-shaped mass in the trachea, about 1 cm below the vocal cords. The surface of the mass was covered with several small and discontinuous blood vessels. About 90% of the tracheal lumen was occupied by the mass. A multidisciplinary operation was performed. The surgically resected mass was diagnosed as benign neurilemmoma by immunohistochemical analysis.

Intratracheal neurilemmoma is fairly rare in children. The main symptoms include coughing, wheezing, and dyspnea. The tumor’s size, location, and degree of intratracheal and extratracheal invasion can be measured by chest computed tomography. The main treatment strategies used for tracheal neurilemmoma are surgical resection and endoscopic excision. Long-term follow-up is warranted for the evaluation of outcomes and complications.

• Airway obstruction
• Trachea
• Neurilemmoma
• Therapeutic bronchoscopy
• Child
• Case report

Primary intratracheal schwannoma is an extremely rare type of benign airway tumor, especially in adolescents. The presenting symptoms are typically prolonged cough and wheezing that can be misdiagnosed as asthma in adolescent patients.

A 16-year-old adolescent girl admitted to a local hospital with symptoms of an irritating cough and wheezing was diagnosed with bronchial asthma and treated with budesonide and formoterol. Over the next year, the patient's wheezing and coughing symptoms gradually worsened and the antiasthma treatment was ineffective. One week prior to this admission, the patient developed dyspnea after catching a cold and was transferred to our hospital with a diagnosis of severe asthma. However, chest computed tomography and bronchoscopy showed a mass in the trachea. Primary intratracheal schwannoma was diagnosed by biopsy. Her symptoms were relieved by endoscopic resection by electrosurgical snaring combined with argon plasma coagulation. No relapse occurred during an 18 mo follow-up.

Primary intratracheal schwannoma should be considered in the differential diagnosis in adolescents with recurrent asthma-like attacks.

• Intratracheal schwannoma
• Adolescent
• Severe asthma
• Misdiagnosis
• Endoscopic resection
• Case report

• Case report
• Microcystic reticular schwannoma
• Neurogenic tracheal tumor
• Primary tracheal schwannoma
• Rare diseases
• Tracheal resection

We report a case of primary tracheal schwannoma in a 31-year-old woman. She had a previous history of follicular thyroid carcinoma treated surgically and Turner syndrome. In a follow-up computed tomography scan, we found a partially obstructing intraluminal tracheal tumor, which was confirmed by bronchoscopy. The patient was treated by surgical resection and primary tracheal anastomosis. The tumor was 14 mm in diameter, with an intact capsule. Histologic analysis revealed a Schwann cell origin tumor.

Neurogenic tumors of the tracheobronchial tree are extremely rare, and these include neurofibroma and schwannoma. The rare schwannoma most frequently is reported in adults. We will report an endobronchial schwannoma in an 11-year-old boy.

• Neurogenic tumors
• Obstructive pneumonia
• Resection
• Schwannoma
• Tracheobronchial tree

• endoscopic excision
• tracheal schwannoma
• tumor recurrence
• video-assisted thoracoscopic surgery
• window resection

• Female
• Humans
• Neurilemmoma/diagnosis
• Neurilemmoma/pathology
• Neurilemmoma/surgery
• Thoracic Surgery, Video-Assisted/methods
• Tomography, X-Ray Computed
• Trachea/pathology
• Trachea/surgery
• Tracheal Neoplasms/diagnosis
• Tracheal Neoplasms/pathology
• Tracheal Neoplasms/surgery
• Young Adult

• Schwannoma
• case report
• cricotracheal approach
• endoscopic
• excision

• cancer intervention
• ear, nose and throat/otolaryngology
• respiratory system

• Endoscopic resection
• Neurogenic tumors
• Recurrence
• Schwannoma
• Surgical resection
• Trachea