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For: Wang YY, Jiang H, Pan J, Huang XR, Wang YC, Huang HF, To KF, Nikolic-Paterson DJ, Lan HY, Chen JH. Macrophage-to-Myofibroblast Transition Contributes to Interstitial Fibrosis in Chronic Renal Allograft Injury. J Am Soc Nephrol 2017;28:2053-2067. [PMID: 28209809 DOI: 10.1681/asn.2016050573] [Citation(s) in RCA: 304] [Impact Index Per Article: 38.0] [Reference Citation Analysis] [What about the content of this article? (0)] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 05/23/2016] [Accepted: 12/14/2016] [Indexed: 01/04/2023]  Open
Number Cited by Other Article(s)
1
Lin Y, Yang Q, Zeng R. Crosstalk between macrophages and adjacent cells in AKI to CKD transition. Ren Fail 2025;47:2478482. [PMID: 40110623 PMCID: PMC11926904 DOI: 10.1080/0886022x.2025.2478482] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/21/2024] [Revised: 02/17/2025] [Accepted: 03/07/2025] [Indexed: 03/22/2025]  Open
2
Tan Y, Wang X, Zhang D, Wang J, Wang S, Yu J, Wu H. Determining IFI44 as a key lupus nephritis's biomarker through bioinformatics and immunohistochemistry. Ren Fail 2025;47:2479575. [PMID: 40101924 PMCID: PMC11921169 DOI: 10.1080/0886022x.2025.2479575] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/07/2024] [Revised: 02/27/2025] [Accepted: 03/06/2025] [Indexed: 03/20/2025]  Open
3
Gao X, Liu X, Han Z, Liao H, Li R. Friend or foe? The role of SIRT6 on macrophage polarized to M2 subtype in acute kidney injury to chronic kidney disease. Ren Fail 2025;47:2482121. [PMID: 40260529 PMCID: PMC12016254 DOI: 10.1080/0886022x.2025.2482121] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/30/2024] [Revised: 02/28/2025] [Accepted: 03/14/2025] [Indexed: 04/23/2025]  Open
4
Lv R, Liu Z, Guo H, Zhang B, Wang X, Peng Y, Chang Y, Yang F, Xiong Y, Hao J, Gao X, Wang X, Xu Q, Shimosawa T, Qiang P. Fibroblast to macrophage-like cell transition in renal inflammatory injury through the MR/CSF1 pathway induced by aldosterone. Life Sci 2025;372:123627. [PMID: 40216224 DOI: 10.1016/j.lfs.2025.123627] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/27/2025] [Revised: 03/25/2025] [Accepted: 04/06/2025] [Indexed: 04/17/2025]
5
Gao Z. New insights into Smad3 in cardiac fibrosis. Gene 2025;952:149418. [PMID: 40089084 DOI: 10.1016/j.gene.2025.149418] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/26/2025] [Revised: 03/04/2025] [Accepted: 03/13/2025] [Indexed: 03/17/2025]
6
Boiko JR, Hill GR. Chronic Graft-versus-host Disease: Immune Insights, Therapeutic Advances, and Parallels for Solid Organ Transplantation. Transplantation 2025;109:955-966. [PMID: 39682018 PMCID: PMC12097962 DOI: 10.1097/tp.0000000000005298] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Grants] [Track Full Text] [Download PDF] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 12/18/2024]
7
Liang W, Wu H, Long Q, Lin H, Lv X, Ma W, Wu T, Li A, Zheng Q, Guo J, Chen X, Guo J, Sun D. LKB1 activated by NaB inhibits the IL-4/STAT6 axis and ameliorates renal fibrosis through the suppression of M2 macrophage polarization. Life Sci 2025;370:123564. [PMID: 40097066 DOI: 10.1016/j.lfs.2025.123564] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/07/2024] [Revised: 03/03/2025] [Accepted: 03/13/2025] [Indexed: 03/19/2025]
8
Guo H, Liu Z, Lv R, Zhang B, Qiang P, Wang X, Chang Y, Yang F, Shimosawa T, Xu Q, Xiong Y. Aldosterone induces renal lymphangiogenesis through macrophage-lymphatic endothelial cell transformation and Inhibition by esaxerenone. Inflamm Res 2025;74:85. [PMID: 40413281 DOI: 10.1007/s00011-025-02044-1] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/03/2025] [Revised: 04/18/2025] [Accepted: 04/25/2025] [Indexed: 05/27/2025]  Open
9
Li Y, Xue L, Feng J, Wang Z, Long Y, Liu W, Zhang S, Zhi X, Hao H, Wang X, Liu H, Wang L. Insufficient BK channel function enhances NF-κB nuclear translocation and promotes IL-6 synthesis in vascular smooth muscle cells induced by AT1-AA. Biochem Pharmacol 2025:117000. [PMID: 40414513 DOI: 10.1016/j.bcp.2025.117000] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/06/2024] [Revised: 04/06/2025] [Accepted: 05/22/2025] [Indexed: 05/27/2025]
10
Chen X, Wu C, Tang F, Zhou J, Mo L, Li Y, He J. The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis. ADVANCED SCIENCE (WEINHEIM, BADEN-WURTTEMBERG, GERMANY) 2025:e05067. [PMID: 40391706 DOI: 10.1002/advs.202505067] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Subscribe] [Scholar Register] [Received: 03/20/2025] [Revised: 04/28/2025] [Indexed: 05/22/2025]
11
Zhao Y, Zhu XY, Ma W, Zhang Y, Yuan F, Kim SR, Tang H, Jordan K, Lerman A, Tchkonia T, Kirkland JL, Lerman LO. Cellular senescence promotes macrophage-to-myofibroblast transition in chronic ischemic renal disease. Cell Death Dis 2025;16:372. [PMID: 40348745 PMCID: PMC12065848 DOI: 10.1038/s41419-025-07666-1] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/29/2024] [Revised: 04/07/2025] [Accepted: 04/14/2025] [Indexed: 05/14/2025]
12
Zhang D, Zhang YH, Liu B, Yang HX, Li GT, Zhou HL, Wang YS. Role of peroxisomes in the pathogenesis and therapy of renal fibrosis. Metabolism 2025;166:156173. [PMID: 39993498 DOI: 10.1016/j.metabol.2025.156173] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 10/06/2024] [Revised: 02/18/2025] [Accepted: 02/20/2025] [Indexed: 02/26/2025]
13
Li Y, Cai J, Xu Y, Zou Y, Xu S, Zheng X, Fu L, Zhang J, Ma X, He Y, Wang X, Deng K, Guo J. Macrophage-myofibroblast transition contributes to the macrophage elimination and functional regeneration in the late stage of nerve injury. Exp Neurol 2025;387:115194. [PMID: 39993460 DOI: 10.1016/j.expneurol.2025.115194] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/17/2025] [Revised: 02/19/2025] [Accepted: 02/20/2025] [Indexed: 02/26/2025]
14
Wang H, Ding K, He J, Wang J. Tetrahydropalmatine promotes macrophage autophagy by inhibiting the AMPK/mTOR pathway to attenuate atherosclerosis. Histol Histopathol 2025;40:697-710. [PMID: 39359170 DOI: 10.14670/hh-18-809] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 10/04/2024]
15
Meng XM, Wang L, Nikolic-Paterson DJ, Lan HY. Innate immune cells in acute and chronic kidney disease. Nat Rev Nephrol 2025:10.1038/s41581-025-00958-x. [PMID: 40263532 DOI: 10.1038/s41581-025-00958-x] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Accepted: 03/24/2025] [Indexed: 04/24/2025]
16
Huang Z, Li Z, Ruan D, Xu Y, Cai H, Liu H, Jin H, He P, Fei Y, Huang J, Wang C, Chen X, Jiang J, Shen W. Dynamic changes of molecular pattern and cellular subpopulation in puncture-induced tendon injury model. iScience 2025;28:112034. [PMID: 40230536 PMCID: PMC11994932 DOI: 10.1016/j.isci.2025.112034] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/20/2023] [Revised: 07/03/2024] [Accepted: 02/12/2025] [Indexed: 04/16/2025]  Open
17
Zhou W, Yu C, Meng T, Jiang Q, Yu F, Yuan H. Glutaminase-responsive nano-carrier for precise rejuvenation of senescent cells by restoring autophagy in chronic kidney disease treatment. Int J Pharm 2025;674:125469. [PMID: 40089039 DOI: 10.1016/j.ijpharm.2025.125469] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/23/2024] [Revised: 02/21/2025] [Accepted: 03/11/2025] [Indexed: 03/17/2025]
18
Zhang ZJ, Casiraghi F, Perkins GB, Baldwin WM, Fairchild RL. Can mouse kidney transplant models inform mechanisms of injury and acceptance in clinical kidney transplantation? Am J Transplant 2025:S1600-6135(25)00172-8. [PMID: 40209906 DOI: 10.1016/j.ajt.2025.04.001] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/26/2024] [Revised: 03/12/2025] [Accepted: 04/02/2025] [Indexed: 04/12/2025]
19
Huang Y, Zhao L, Zhao Y, Fan Y, Gao L, Lu H, Wang X, Mo D, Wang D. Anti-Radiofibrosis Effect of Dicliptera chinensis Polysaccharide on Rat Dermal Fibroblasts Via The TGF-β1/Smads/CTGF Signaling Pathway. Int Dent J 2025;75:1338-1347. [PMID: 39394033 PMCID: PMC11976618 DOI: 10.1016/j.identj.2024.09.024] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/25/2024] [Revised: 09/08/2024] [Accepted: 09/19/2024] [Indexed: 10/13/2024]  Open
20
Peng Y, Mei S, Qi X, Tang R, Yang W, Feng J, Zhou Y, Huang X, Qian G, Xing S, Gao Y, Xu Q, He Z. PGC-1α mediates migrasome secretion accelerating macrophage-myofibroblast transition and contributing to sepsis-associated pulmonary fibrosis. Exp Mol Med 2025;57:759-774. [PMID: 40164683 PMCID: PMC12046055 DOI: 10.1038/s12276-025-01426-z] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/23/2024] [Revised: 12/29/2024] [Accepted: 01/01/2025] [Indexed: 04/02/2025]  Open
21
Mu YF, Mao ZH, Pan SK, Liu DW, Liu ZS, Wu P, Gao ZX. Macrophage-driven inflammation in acute kidney injury: Therapeutic opportunities and challenges. Transl Res 2025;278:1-9. [PMID: 39954848 DOI: 10.1016/j.trsl.2025.02.003] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 07/06/2024] [Revised: 02/08/2025] [Accepted: 02/12/2025] [Indexed: 02/17/2025]
22
Wang W, Jin Y, Liu MK, Zhang SY, Chen H, Song J. Current Progress of Hederagenin and Its Derivatives for Disease Therapy (2017-Present). Molecules 2025;30:1275. [PMID: 40142049 PMCID: PMC11944430 DOI: 10.3390/molecules30061275] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/21/2025] [Revised: 02/24/2025] [Accepted: 03/03/2025] [Indexed: 03/28/2025]  Open
23
Yao Q, Zheng X, Zhang X, Wang Y, Zhou Q, Lv J, Zheng L, Lan J, Chen W, Chen J, Chen D. METTL3 Potentiates M2 Macrophage-Driven MMT to Aggravate Renal Allograft Fibrosis via the TGF-β1/Smad3 Pathway. ADVANCED SCIENCE (WEINHEIM, BADEN-WURTTEMBERG, GERMANY) 2025;12:e2412123. [PMID: 39869489 PMCID: PMC11923867 DOI: 10.1002/advs.202412123] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Subscribe] [Scholar Register] [Received: 09/29/2024] [Revised: 01/09/2025] [Indexed: 01/29/2025]
24
Sun S, Han B, Ren G, Fan L, Sun J, Li H, Huang J. MTHFD2 stabilizes LOX expression through RNA methylation modification to promote sepsis-induced acute kidney injury progression. Hum Cell 2025;38:62. [PMID: 40009304 DOI: 10.1007/s13577-025-01189-9] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/14/2024] [Accepted: 02/14/2025] [Indexed: 02/27/2025]
25
Xia Y, Ye Z, Li B, Yan X, Yuan T, Li L, Song B, Yu W, Rao T, Ning J, Zhu J, Li X, Mei S, Mao Z, Zhou X, Cheng F. EZH2-mediated macrophage-to-myofibroblast transition contributes to calcium oxalate crystal-induced kidney fibrosis. Commun Biol 2025;8:286. [PMID: 39987296 PMCID: PMC11846861 DOI: 10.1038/s42003-025-07735-3] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 05/14/2024] [Accepted: 02/13/2025] [Indexed: 02/24/2025]  Open
26
Fu T, Zhou J, Yang L, Wang J, Li H, Shan Y, Gao H, Xie C, Jiang D, Zhang L, Ma J, Pan Q, Xu M, Zhang M, Gu S. Neutrophil-induced pyroptosis promotes survival in patients with hepatoblastoma. Cancer Immunol Immunother 2025;74:106. [PMID: 39932547 PMCID: PMC11813845 DOI: 10.1007/s00262-024-03922-z] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/02/2024] [Accepted: 12/11/2024] [Indexed: 02/14/2025]
27
Ha S, Son M, Kim J, Kim D, Kim MJ, Yoo J, Kim BM, Kim D, Chung HY, Chung KW. Gender Differences in Adenine Diet-Induced Kidney Toxicity: The Impact of 17β-Estradiol on Renal Inflammation and Fibrosis. Int J Mol Sci 2025;26:1358. [PMID: 39941126 PMCID: PMC11818771 DOI: 10.3390/ijms26031358] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/16/2025] [Revised: 02/03/2025] [Accepted: 02/04/2025] [Indexed: 02/16/2025]  Open
28
Yang Z, Shi L, Wang Y, Zhou D, Zhang C, Lin Y. Unveiling the Potential of Tetrahedral DNA Frameworks in Clinical Medicine: Mechanisms, Advances, and Future Perspectives. SMALL (WEINHEIM AN DER BERGSTRASSE, GERMANY) 2025;21:e2410162. [PMID: 39707665 DOI: 10.1002/smll.202410162] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Subscribe] [Scholar Register] [Received: 10/29/2024] [Revised: 11/24/2024] [Indexed: 12/23/2024]
29
Li P, Ji W, Zhang B, Jia H, Wang J, Sun Z, Wang Y, Wang W, Qi F. FPR1 affects acute rejection in kidney transplantation by regulating iron metabolism in neutrophils. Mol Med 2025;31:23. [PMID: 39849390 PMCID: PMC11758745 DOI: 10.1186/s10020-025-01077-w] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/29/2024] [Accepted: 01/10/2025] [Indexed: 01/25/2025]  Open
30
Zhong Q, Zeng J, Li Y, Zhang H, Lin T, Song T. Senescent renal tubular cells derived extracellular vesicles transported miR-20a and miR-21 induced macrophage-to-myofibroblast transition in renal fibrosis after ischemia reperfusion injury. Int J Biol Sci 2025;21:940-954. [PMID: 39897045 PMCID: PMC11781180 DOI: 10.7150/ijbs.97579] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/21/2024] [Accepted: 12/09/2024] [Indexed: 02/04/2025]  Open
31
Lv Y, Hua Z, Lu X. Protective effects and possible mechanisms of mesenchymal stem cells and mesenchymal stem cell-derived extracellular vesicles against kidney fibrosis in animal models: a systematic review and meta-analysis. Front Pharmacol 2025;15:1511525. [PMID: 39830341 PMCID: PMC11739157 DOI: 10.3389/fphar.2024.1511525] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/15/2024] [Accepted: 12/05/2024] [Indexed: 01/22/2025]  Open
32
Zhou L, Gong L, Liu Z, Xiang J, Ren C, Xu Y. Probiotic interventions with highly acid-tolerant Levilactobacillus brevis strains improve lipid metabolism and gut microbial balance in obese mice. Food Funct 2025;16:112-132. [PMID: 39621366 DOI: 10.1039/d4fo03417a] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 12/11/2024]
33
Sun J, Shi M, Mei R, Zhao Y, Huang Y, Song Z, Hua F, Zhang M, Liu J. LincR-PPP2R5C regulates the PP2A signaling pathway in the macrophage-myofibroblast transition in a mouse model of epidural fibrosis. Mol Immunol 2025;177:85-95. [PMID: 39729722 DOI: 10.1016/j.molimm.2024.12.006] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/15/2024] [Revised: 11/18/2024] [Accepted: 12/23/2024] [Indexed: 12/29/2024]
34
Janosevic D, De Luca T, Eadon MT. The Kidney Precision Medicine Project and Single-Cell Biology of the Injured Proximal Tubule. THE AMERICAN JOURNAL OF PATHOLOGY 2025;195:7-22. [PMID: 39332674 PMCID: PMC11686451 DOI: 10.1016/j.ajpath.2024.09.006] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Grants] [Track Full Text] [Subscribe] [Scholar Register] [Received: 06/26/2024] [Revised: 08/29/2024] [Accepted: 09/11/2024] [Indexed: 09/29/2024]
35
Jia Q, Ding Y, Su Z, Chen H, Ye J, Xie D, Wu Y, He H, Peng Y, Ni Y. Cell membrane-camouflaged nanoparticles activate fibroblast-myofibroblast transition to promote skin wound healing. Biofabrication 2024;17:015036. [PMID: 39657324 DOI: 10.1088/1758-5090/ad9cc4] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/27/2024] [Accepted: 12/10/2024] [Indexed: 12/12/2024]
36
Wang K, Zhang L, Deng B, Zhao K, Chen C, Wang W. Mitochondrial uncoupling protein 2: a central player in pancreatic disease pathophysiology. Mol Med 2024;30:259. [PMID: 39707176 DOI: 10.1186/s10020-024-01027-y] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/07/2024] [Accepted: 12/03/2024] [Indexed: 12/23/2024]  Open
37
Zhang J, Huang J, Yang Q, Zeng L, Deng K. Regulatory mechanisms of macrophage-myofibroblast transdifferentiation: A potential therapeutic strategy for fibrosis. Biochem Biophys Res Commun 2024;737:150915. [PMID: 39486135 DOI: 10.1016/j.bbrc.2024.150915] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/09/2024] [Revised: 10/27/2024] [Accepted: 10/27/2024] [Indexed: 11/04/2024]
38
Jiang Y, Cai R, Huang Y, Zhu L, Xiao L, Wang C, Wang L. Macrophages in organ fibrosis: from pathogenesis to therapeutic targets. Cell Death Discov 2024;10:487. [PMID: 39632841 PMCID: PMC11618518 DOI: 10.1038/s41420-024-02247-1] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/25/2024] [Revised: 11/11/2024] [Accepted: 11/13/2024] [Indexed: 12/07/2024]  Open
39
Li J, Yan X, Wu Z, Shen J, Li Y, Zhao Y, Du F, Li M, Wu X, Chen Y, Xiao Z, Wang S. Role of miRNAs in macrophage-mediated kidney injury. Pediatr Nephrol 2024;39:3397-3410. [PMID: 38801452 DOI: 10.1007/s00467-024-06414-5] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 01/15/2024] [Revised: 04/13/2024] [Accepted: 05/03/2024] [Indexed: 05/29/2024]
40
Bøgh N, Bertelsen LB, Rasmussen CW, Bech SK, Keller AK, Madsen MG, Harving F, Thorsen TH, Mieritz IK, Hansen ES, Wanders A, Laustsen C. Metabolic MRI With Hyperpolarized 13 C-Pyruvate for Early Detection of Fibrogenic Kidney Metabolism. Invest Radiol 2024;59:813-822. [PMID: 38913443 DOI: 10.1097/rli.0000000000001094] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 06/26/2024]
41
Yu W, Song J, Chen S, Nie J, Zhou C, Huang J, Liang H. Myofibroblast-derived exosomes enhance macrophages to myofibroblasts transition and kidney fibrosis. Ren Fail 2024;46:2334406. [PMID: 38575341 PMCID: PMC10997357 DOI: 10.1080/0886022x.2024.2334406] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 04/06/2024]  Open
42
Guo Q, Li P, Chen M, Yu Y, Wan Y, Zhang Z, Ren C, Shen L, Liu X, He D, Zhang Y, Wei G, Zhang D. Exosomes From Human Umbilical Cord Stem Cells Suppress Macrophage-to-myofibroblast Transition, Alleviating Renal Fibrosis. Inflammation 2024;47:2094-2107. [PMID: 38662165 DOI: 10.1007/s10753-024-02027-0] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/12/2024] [Revised: 04/10/2024] [Accepted: 04/12/2024] [Indexed: 04/26/2024]
43
Hu Y, Wang Y, Hong H, Chen Y, Zhou Q, Zhu G, Tang J, Liu W, Wang L. Global trends and prospects related to macrophage in chronic kidney disease: a bibliometric analysis. Ren Fail 2024;46:2423846. [PMID: 39572163 PMCID: PMC11583328 DOI: 10.1080/0886022x.2024.2423846] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/04/2024] [Revised: 10/11/2024] [Accepted: 10/27/2024] [Indexed: 11/24/2024]  Open
44
Zeng J, Du XL, Lu QQ, Chen WQ, Yang XJ. Inhibition of GDNF-Driven Macrophage-to-Myofibroblast Transition Protects Against Colitis-Associated Intestinal Fibrosis. Inflammation 2024. [DOI: 10.1007/s10753-024-02175-3] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/31/2023] [Revised: 10/03/2024] [Accepted: 10/27/2024] [Indexed: 01/03/2025]
45
Zuo YB, Wen ZJ, Cheng MD, Jia DD, Zhang YF, Yang HY, Xu HM, Xin H, Zhang YF. The pro-atherogenic effects and the underlying mechanisms of chronic bisphenol S (BPS) exposure in apolipoprotein E-deficient mice. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY 2024;285:117133. [PMID: 39342757 DOI: 10.1016/j.ecoenv.2024.117133] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Subscribe] [Scholar Register] [Received: 04/30/2024] [Revised: 07/23/2024] [Accepted: 09/26/2024] [Indexed: 10/01/2024]
46
Ban JQ, Ao LH, He X, Zhao H, Li J. Advances in macrophage-myofibroblast transformation in fibrotic diseases. Front Immunol 2024;15:1461919. [PMID: 39445007 PMCID: PMC11496091 DOI: 10.3389/fimmu.2024.1461919] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/10/2024] [Accepted: 09/26/2024] [Indexed: 10/25/2024]  Open
47
Liu T, Zhang Y, Wu Z, Zhao CJ, Dong X, Gong HX, Jin B, Han MM, Wu JJ, Fan YK, Li N, Xiong YX, Zhang ZQ, Dong ZQ. Novel glucomannan-like polysaccharide from Lycium barbarum L. ameliorates renal fibrosis via blocking macrophage-to-myofibroblasts transition. Int J Biol Macromol 2024;278:134491. [PMID: 39111495 DOI: 10.1016/j.ijbiomac.2024.134491] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/04/2024] [Revised: 07/18/2024] [Accepted: 08/02/2024] [Indexed: 08/26/2024]
48
Owen MC, Kopecky BJ. Targeting Macrophages in Organ Transplantation: A Step Toward Personalized Medicine. Transplantation 2024;108:2045-2056. [PMID: 38467591 PMCID: PMC11390981 DOI: 10.1097/tp.0000000000004978] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 03/13/2024]
49
Chen C, Feng C, Luo Q, Zeng Y, Yuan W, Cui Y, Tang Z, Zhang H, Li T, Peng J, Peng L, Xie X, Guo Y, Peng F, Jiang X, Bai P, Qi Z, Dai H. CD5L up-regulates the TGF-β signaling pathway and promotes renal fibrosis. Life Sci 2024;354:122945. [PMID: 39127319 DOI: 10.1016/j.lfs.2024.122945] [Citation(s) in RCA: 1] [Impact Index Per Article: 1.0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 06/17/2024] [Revised: 07/25/2024] [Accepted: 08/04/2024] [Indexed: 08/12/2024]
50
Li X, Liu Y, Tang Y, Xia Z. Transformation of macrophages into myofibroblasts in fibrosis-related diseases: emerging biological concepts and potential mechanism. Front Immunol 2024;15:1474688. [PMID: 39386212 PMCID: PMC11461261 DOI: 10.3389/fimmu.2024.1474688] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/02/2024] [Accepted: 09/06/2024] [Indexed: 10/12/2024]  Open
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