The article "Secondary diabetes due to different etiologies: Four case reports" by Song et al, published in the World Journal of Clinical Cases, delves into the identification of rare causes of secondary diabetes and emphasizes the necessity for healthcare professionals to recognize these conditions. Failure to do so can result in treatment delays and compromised patient outcomes. The article discusses specific types of diabetes, including maturity onset of diabetes in young, pancreas-related diseases, endocrinopathies, drug-induced diabetes, infections, and congenital genetic syndromes associated with diabetes mellitus. Case summaries highlight how patients with secondary diabetes, stemming from conditions such as Williams-Beuren syndrome and pituitary adenoma, often exhibit distinct characteristics overlooked in clinical practice. The authors stress the importance of a holistic diagnostic approach and advocate for proactive management through early intervention, including genetic tests and antibody detection. Increased awareness and education are crucial for timely identification and proper management, ultimately improving patient well-being. These findings prompt a call to action for healthcare professionals to consider rare causes of secondary diabetes, facilitating better glycemic control and overall patient care.

There are many factors in the occurrence of diabetes, which can result in insufficient insulin secretion and insulin receptor resistance. Including pituitary tumors, can also lead to the occurrence of diabetes, if the primary disease can not be well controlled in time, such secondary diabetes control is more difficult. In the process of clinical diagnosis and treatment, these factors need to be taken into account, timely detection and treatment of primary diseases, so as to reduce the possibility of clinical missed diagnosis.