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Gastañaga-Holguera T, Campo Gesto I, Gómez-Irwin L, Calvo Urrutia M. Differential diagnosis of uterine vascular anomalies: Uterine pseudoaneurysm as a cause of massive hemorrhage. World J Clin Cases 2025; 13:99671. [PMID: 40144488 PMCID: PMC11670028 DOI: 10.12998/wjcc.v13.i9.99671] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 07/27/2024] [Revised: 11/18/2024] [Accepted: 12/02/2024] [Indexed: 12/12/2024] Open
Abstract
In this article, we comment on the paper by Kakinuma et al published recently. We focus specifically on the diagnosis of uterine pseudoaneurysm, but we also review other uterine vascular anomalies that may be the cause of life-threating hemorrhage and the different causes of uterine pseudoaneurysms. Uterine artery pseudoaneurysm is a complication of both surgical gynecological and non-traumatic procedures. Massive hemorrhage is the consequence of the rupture of the pseudoaneurysm. Uterine artery pseudoaneurysm can develop after obstetric or gynecological procedures, being the most frequent after cesarean or vaginal deliveries, curettage and even during pregnancy. However, there are several cases described unrelated to pregnancy, such as after conization, hysteroscopic surgery or laparoscopic myomectomy. Hemorrhage is the clinical manifestation and it can be life-threatening so suspicion of this vascular lesion is essential for early diagnosis and treatment. However, there are other uterine vascular anomalies that may be the cause of severe hemorrhage, which must be taken into account in the differential diagnosis. Computed tomography angiography and embolization is supposed to be the first therapeutic option in most of them.
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Affiliation(s)
| | - Isabel Campo Gesto
- Department of Obstetrics and Gynecology, San Carlos Clinical Hospital, Madrid 28040, Spain
| | - Laura Gómez-Irwin
- Department of Gastroenterology, University Hospital of Cruces, Baracaldo 48903, Bizkaia, Spain
| | - Marta Calvo Urrutia
- Department of Obstetrics and Gynecology, San Carlos Clinical Hospital, Madrid 28040, Spain
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Okpete UE, Byeon H. Importance of timely diagnosis and intervention in uterine artery pseudoaneurysm caused by hysteroscopic surgery. World J Clin Cases 2024; 12:6740-6743. [PMID: 39650825 PMCID: PMC11514354 DOI: 10.12998/wjcc.v12.i34.6740] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 07/19/2024] [Revised: 09/15/2024] [Accepted: 09/27/2024] [Indexed: 10/12/2024] Open
Abstract
This manuscript explores the case on the occurrence of uterine artery pseudoaneurysm (UAP) during hysteroscopy endometrial polypectomy and the subsequent successful treatment via uterine artery embolization (UAE). Moreover, we focus on the management and treatment options for UAP in patients of advanced maternal age. A pseudoaneurysm is an extraluminal blood collection with a disrupted flow that communicates with the parent vessel via a defect in the arterial wall. The reported case involved a 48-year-old primiparous woman who developed a UAP after uterine polyp removal. The study enhances the understanding of UAP, a rare but potentially life-threatening condition, by providing a detailed and well-documented account of the comprehensive case presentation, effective use of medical imaging techniques for diagnosis, successful postoperative patient management following UAE, and practical clinical recommendations for clinicians managing similar cases. Overall, this study highlights the importance of considering UAP as a differential diagnosis in patients with abnormal vaginal bleeding following hysteroscopic surgery. Additionally, this manuscript recommends that clinicians with a high index of suspicion for UAP promptly request ultrasonography and computed tomography to facilitate early diagnosis. UAE is suggested as a primary treatment due to its effectiveness and safety, particularly in facilities capable of avoiding hysterectomy.
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Affiliation(s)
- Uchenna E Okpete
- Department of Digital Anti-aging Healthcare (BK21), Inje University, Gimhae 50834, South Korea
| | - Haewon Byeon
- Department of Digital Anti-aging Healthcare (BK21), Inje University, Gimhae 50834, South Korea
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Crouzat A, Gauci PA. Treatment of uterine artery (pseudo)aneurysm during pregnancy: A case report and review of the literature. Eur J Obstet Gynecol Reprod Biol 2024; 299:240-247. [PMID: 38905967 DOI: 10.1016/j.ejogrb.2024.05.046] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/04/2024] [Revised: 05/07/2024] [Accepted: 05/31/2024] [Indexed: 06/23/2024]
Abstract
PURPOSE To describe the management of uterine artery (pseudo)aneurysm, ruptured or unruptured, during pregnancy. METHODS After reporting a case about this rare pathology, a review of the literature was performed. The search was applied to PubMed databases. RESULTS A total of eighteen articles met the inclusion criteria. Eighteen patients were reported. Eight (44.4 %) patients didn't have prior medical or surgical history. Fifteen (83.3 %) beneficed interventional radiology method during pregnancy including two cases (13.3 %) with repeated embolization because of recanalization of the (pseudo)aneurysm. Nine patients (50 %) beneficed a planned cesarean between 34 and 39 weeks of gestation. One (15.8 %) patient was diagnosed with fetal death before treatment of the uterine artery (pseudo)aneurysm. CONCLUSION The decision to proceed to the treatment of the (pseudo)aneurysm must consider several factors, associated or not with a good fetal vitality and a hemodynamically stable patient. Embolization appears to be the method of choice. Mode of delivery and term remain not clear and contraindication of expulsive efforts in case of a uterine artery (pseudo)aneurysm merit further investigations.
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Affiliation(s)
- Améline Crouzat
- Department of Obstetrics and Gynecology, Reproduction and Fetal Medicine, CHU de Nice, University of Côte d'Azur, Hôpital Archet 2, 151 Route de Saint-Antoine, CS 23079 06200 Nice, France
| | - Pierre-Alexis Gauci
- Université Côte d'Azur - Centre Hospitalier Universitaire de Nice, UMR2CA, France, Hôpital Archet 2, 151 Route de Saint-Antoine, CS 23079 06200 Nice, France.
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Toshimitsu M, Iriyama T, Sato J, Abe O, Ichinose M, Sayama S, Seyama T, Sone K, Kumasawa K, Osuga Y. A Case of Ruptured Exophytic Uterine Artery Pseudoaneurysm without Specific Risk Factors That Manifested Seven Days after Vaginal Delivery. Case Rep Obstet Gynecol 2023; 2023:1637463. [PMID: 38046834 PMCID: PMC10693466 DOI: 10.1155/2023/1637463] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/29/2023] [Revised: 11/12/2023] [Accepted: 11/13/2023] [Indexed: 12/05/2023] Open
Abstract
A uterine artery pseudoaneurysm (UAP) is a life-threatening complication during pregnancy and postpartum. Early diagnosis of exophytic UAP rupture is difficult due to the absence of vaginal bleeding. This study reports the case of a 31-year-old postpartum woman who presented with abdominal pain and fever seven days after vaginal delivery, without symptoms of maternal shock. Ultrasonography revealed a ruptured exophytic UAP with hemoperitoneum, which was confirmed using computed tomography. Interventional radiology confirmed that the site of the pseudoaneurysm was at the level of the uterine artery bifurcation, and embolization was performed immediately after diagnosis using a coil and n-butyl-2-cyanoacrylate. The patient's symptoms were relieved, and she was discharged 12 days after the embolization. At eight months postpartum, the UAP was not visible on transvaginal ultrasonography. Exophytic UAP can occur even in the absence of specific risk factors such as cesarean section or endometriosis, and the UAP may not necessarily rupture immediately after delivery. Obstetricians must remain aware of the possibility of exophytic UAP rupture manifesting as abdominal pain with postpartum fever, rather than as unstable vital signs. This is the first report of an exophytic UAP that occurred at the level of the uterine artery bifurcation. Identification of the sites where exophytic UAP can occur can aid in the early diagnosis of the condition.
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Affiliation(s)
- Masatake Toshimitsu
- Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan
| | - Takayuki Iriyama
- Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan
| | - Jiro Sato
- Department of Radiology, Tokyo Metropolitan Police Hospital, 4-22-1, Nakano, Nakano-ku, Tokyo 164-8541, Japan
| | - Osamu Abe
- Department of Radiology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan
| | - Mari Ichinose
- Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan
| | - Seisuke Sayama
- Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan
| | - Takahiro Seyama
- Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan
| | - Kenbun Sone
- Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan
| | - Keiichi Kumasawa
- Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan
| | - Yutaka Osuga
- Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan
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Jannusch K, Steuwe A, Schimmöller L, Dietzel F, Wilms LM, Weiss D, Ziayee F, Fehm TN, Schlimgen C, Poth V, Ziegler RT, Minko P. Endovascular coil-embolization of an unruptured, true UAA during early pregnancy- a case report. CVIR Endovasc 2023; 6:50. [PMID: 37870638 PMCID: PMC10593720 DOI: 10.1186/s42155-023-00398-3] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/16/2023] [Accepted: 10/11/2023] [Indexed: 10/24/2023] Open
Abstract
BACKGROUND True uterine artery aneurysms, especially during pregnancy, are a rare entity and not well understood. Clinical symptoms are unspecific pelvic pain and pressure. Diagnosis can be confirmed by transvaginal color-coded-sonography and/or magnetic resonance imaging. Because of potential risk of rupture, immediate interdisciplinary discussion and treatment planning in the best interests of both mother and child is crucial. CASE PRESENTATION We present a 31-year-old pregnant woman with increasing pelvic pain and pressure. Diagnosis of an unruptured uterine artery aneurysm was confirmed by color-coded-sonography and magnetic resonance angiography. After interdisciplinary consultation, successful endovascular super-selective coil-embolization was performed by using X-ray fluoroscopy. Thus, fetal radiation dose during treatment with 4.33 mGy (VirtualDoseTM) was as low as possible with no immediate harm to the fetus. CONCLUSIONS Unruptured true uterine artery aneurysms can be successfully treated by endovascular super-selective coil-embolization during early pregnancy with no immediate harm to the fetus.
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Affiliation(s)
- Kai Jannusch
- Medical Faculty, Department of Diagnostic and Interventional Radiology, University Dusseldorf, Moorenstrasse 5, Dusseldorf, D-40225, Germany.
| | - Andrea Steuwe
- Medical Faculty, Department of Diagnostic and Interventional Radiology, University Dusseldorf, Moorenstrasse 5, Dusseldorf, D-40225, Germany
| | - Lars Schimmöller
- Medical Faculty, Department of Diagnostic and Interventional Radiology, University Dusseldorf, Moorenstrasse 5, Dusseldorf, D-40225, Germany
| | - Frederic Dietzel
- Medical Faculty, Department of Diagnostic and Interventional Radiology, University Dusseldorf, Moorenstrasse 5, Dusseldorf, D-40225, Germany
| | - Lena M Wilms
- Medical Faculty, Department of Diagnostic and Interventional Radiology, University Dusseldorf, Moorenstrasse 5, Dusseldorf, D-40225, Germany
| | - Daniel Weiss
- Medical Faculty, Department of Diagnostic and Interventional Radiology, University Dusseldorf, Moorenstrasse 5, Dusseldorf, D-40225, Germany
| | - Farid Ziayee
- Medical Faculty, Department of Diagnostic and Interventional Radiology, University Dusseldorf, Moorenstrasse 5, Dusseldorf, D-40225, Germany
| | - Tanja Natascha Fehm
- Medical Faculty, Department of Gynecology, University Dusseldorf, Dusseldorf, D-40225, Germany
| | - Charlotte Schlimgen
- Medical Faculty, Department of Gynecology, University Dusseldorf, Dusseldorf, D-40225, Germany
| | - Vanessa Poth
- Department of Gynecology, Hermann-Josef Hospital, Erkelenz, D-41812, Germany
| | - Reinhold Thomas Ziegler
- Medical Faculty, Department of Vascular and Endovascular Surgery, University Dusseldorf, Dusseldorf, D-40225, Germany
| | - Peter Minko
- Medical Faculty, Department of Diagnostic and Interventional Radiology, University Dusseldorf, Moorenstrasse 5, Dusseldorf, D-40225, Germany
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Metz CK, Hinkson L, Gebauer B, Henrich W. Embolization of uterine artery pseudoaneurysm during pregnancy: case report and review of the literature. CASE REPORTS IN PERINATAL MEDICINE 2023; 12:20220010. [PMID: 40041275 PMCID: PMC11616973 DOI: 10.1515/crpm-2022-0010] [Citation(s) in RCA: 4] [Impact Index Per Article: 2.0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/24/2022] [Accepted: 07/17/2022] [Indexed: 03/06/2025]
Abstract
Objectives Uterine artery pseudoaneurysm (UAP) is a rare but sinister complication during pregnancy. Diagnosis can be made by color Doppler ultrasound. Previous abdominal- and obstetric surgery increase the risk for UAP formation. Case presentation We present a case of a 36 year young healthy women, presenting at 27 weeks of gestation with acute lower abdominal pain. UAP was detected by color Doppler ultrasound. An endovascular coil embolization was performed, with good maternal and fetal outcome. Furthermore, a review of the literature looking at UAP embolization in pregnancy was performed. Conclusions UAP is reported to appear as a complication of endometriosis. UAP should be treated by endovascular coil embolization, which is a safe and with almost 100% success rate an effective treatment during pregnancy.
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Affiliation(s)
- Charlotte K. Metz
- Department of Obstetrics, Charité – Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany
- Department of Radiology, Charité – Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany
| | - Larry Hinkson
- Department of Obstetrics, Charité – Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany
| | - Bernhard Gebauer
- Department of Radiology, Charité – Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany
| | - Wolfgang Henrich
- Department of Obstetrics, Charité – Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany
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Uterine Artery Pseudoaneurysm after an Uncomplicated Vaginal Delivery: A Case Report. Clin Pract 2022; 12:826-831. [PMID: 36286073 PMCID: PMC9600904 DOI: 10.3390/clinpract12050087] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/10/2022] [Revised: 09/28/2022] [Accepted: 10/10/2022] [Indexed: 11/07/2022] Open
Abstract
Uterine artery pseudoaneurysm (UAP) is a rare and potentially life-threatening vascular anomaly caused by inadequate sealing of a ruptured wall of a uterine artery. It mainly occurs after a traumatic lesion and can lead to delayed postpartum hemorrhage. We report a rare case of UAP after an uncomplicated vaginal delivery in a patient with a history of deep-infiltrating endometriosis. Selective coil embolization was successfully performed. UAPs should always be considered in cases of unexplained abdominal pain after surgery or childbirth with or without vaginal bleeding.
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8
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O’Sullivan C, Saenz A. Uterine artery embolization during pregnancy. Proc AMIA Symp 2022; 35:377-378. [DOI: 10.1080/08998280.2022.2035188] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 10/18/2022] Open
Affiliation(s)
| | - Anastacio Saenz
- Texas A&M University College of Medicine, Temple, Texas
- Department of Interventional Radiology, Baylor Scott & White Medical Center – Temple, Temple, Texas
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Wang J, Yang Q, Zhang N, Wang D. Uterine artery pseudoaneurysm after treatment of cesarean scar pregnancy: a case report. BMC Pregnancy Childbirth 2021; 21:689. [PMID: 34627190 PMCID: PMC8501730 DOI: 10.1186/s12884-021-04166-w] [Citation(s) in RCA: 2] [Impact Index Per Article: 0.5] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/01/2021] [Accepted: 09/30/2021] [Indexed: 01/16/2023] Open
Abstract
BACKGROUND Pseudoaneurysms are formed when a local arterial wall ruptures, leading to hemorrhage and hematoma adjacent to the artery. Continuous perfusion of the injured artery increases the pressure in the lumen of the pseudoaneurysm. It may rupture and lead to massive hemorrhage that could be life-threatening. Cesarean scar pregnancy (CSP) is an ectopic pregnancy where the gestational sac is implanted in the cesarean scar. Uterine artery pseudoaneurysm (UAP) after CSP treatment is rare. CASE PRESENTATION We report the case of a 36-year-old Chinese woman who presented with acute massive vaginal bleeding 53 days after transabdominal scar pregnancy excision. Doppler ultrasound confirmed UAP. Selective uterine artery embolization (UAE) failed because of the thin and curved blood vessels. The lesion decreased in size after transvaginal ultrasound-guided direct thrombin injection (UGTI); however, massive vaginal bleeding recurred and endangered the patient's life. The uterus was removed thereafter. CONCLUSIONS UAP is a rare complication after CSP treatment that can lead to fatal massive hemorrhage. Ultrasound should be reexamined regularly after treatment of CSP. In case of unexplained vaginal bleeding, we should be alert to the existence of UAP and the possibility of rupture and take effective diagnosis and treatment measures promptly.
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Affiliation(s)
- Jiao Wang
- Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, No.36 Sanhao Street, Heping District, Shenyang, 110004, P.R. China
| | - Qing Yang
- Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, No.36 Sanhao Street, Heping District, Shenyang, 110004, P.R. China
| | - Ningning Zhang
- Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, No.36 Sanhao Street, Heping District, Shenyang, 110004, P.R. China
| | - Dandan Wang
- Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, No.36 Sanhao Street, Heping District, Shenyang, 110004, P.R. China.
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Zwimpfer TA, Monod C, Redling K, Willi H, Takes M, Fellmann-Fischer B, Manegold-Brauer G, Hösli I. Uterine pseudoaneurysm on the basis of deep infiltrating endometriosis during pregnancy-a case report. BMC Pregnancy Childbirth 2021; 21:282. [PMID: 33836672 PMCID: PMC8034083 DOI: 10.1186/s12884-021-03753-1] [Citation(s) in RCA: 5] [Impact Index Per Article: 1.3] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/15/2020] [Accepted: 03/24/2021] [Indexed: 11/23/2022] Open
Abstract
Background Pseudoaneurysm of the uterine artery (UPA) is a rare cause of potentially life-threatening hemorrhage during pregnancy and puerperium. It is an uncommon condition that mainly occurs after traumatic injury to a vessel following pelvic surgical intervention, but also has been reported based on underlying endometriosis. There is an increased risk of developing UPA during pregnancy. Diagnosis includes clinical symptoms, with severe abdominal pain and is confirmed by sonographic or magnetic resonance imaging (MRI). Due to its potential risk of rupture, with a subsequent hypovolemic maternal shock and high fetal mortality, an interdisciplinary treatment should be considered expeditiously. Case presentation We present the case of a 34-year old pregnant symptomatic patient, where a large UPA was detected at 26 weeks, based on deep infiltrating endometriosis (DIE). The UPA was successfully treated by selective arterial embolization. After embolization, the pain decreased but the woman still required intravenous analgesics during follow-up. At 37 weeks she developed a sepsis from the intravenous catheter which led to a cesarean section and delivery of a healthy boy. She was discharged 10 days postpartum. Conclusions UPA should be considered in pregnant women with severe abdominal and pelvic pain, once other obstetrical factors have been excluded. DIE might be the underlying diagnosis. It is a rare but potentially life-threatening condition for mother and fetus.
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Affiliation(s)
- Tibor Andrea Zwimpfer
- Department of Obstetrics and Gynecology, University Hospital of Basel, Basel, Switzerland. .,Department of Biomedicine, University Hospital of Basel and University Basel, Basel, Switzerland.
| | - Cécile Monod
- Department of Obstetrics and Gynecology, University Hospital of Basel, Basel, Switzerland
| | - Katharina Redling
- Department of Obstetrics and Gynecology, University Hospital of Basel, Basel, Switzerland
| | - Heike Willi
- Department of Obstetrics and Gynecology, University Hospital of Basel, Basel, Switzerland
| | - Martin Takes
- Department of Radiology and Nuclear Medicine, University Hospital of Basel, Basel, Switzerland
| | | | | | - Irene Hösli
- Department of Obstetrics and Gynecology, University Hospital of Basel, Basel, Switzerland
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Mulkers A, Podevyn K, Dehaene I. Recurrent uterine artery pseudo-aneurysm requiring repeat embolization during pregnancy - A case report. Case Rep Womens Health 2021; 29:e00280. [PMID: 33457211 PMCID: PMC7797517 DOI: 10.1016/j.crwh.2020.e00280] [Citation(s) in RCA: 1] [Impact Index Per Article: 0.3] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/06/2020] [Revised: 12/08/2020] [Accepted: 12/10/2020] [Indexed: 11/21/2022] Open
Abstract
Background Uterine artery pseudo-aneurysms (UAP) mainly occur after traumatic delivery or traumatic pregnancy termination. A UAP can be either asymptomatic or present with symptoms such as vaginal bleeding, abdominal pain, hypovolemic shock, or fever when infected. We describe a patient diagnosed with a uterine artery pseudo-aneurysm in pregnancy that required repeat embolization. The patient had no risk factors in her recent medical history. She did, however, undergo in-vitro fertilization with oocyte retrieval performed under transvaginal ultrasonographic guidance. We suggest the hypothesis of formation of the pseudo-aneurysm secondary to vascular injury during oocyte retrieval. Case Report A 35-year-old primigravida, who conceived by in-vitro fertilization, presenting with severe abdominal pain at 19 2/7 weeks of gestation. Ultrasound examination with color doppler imaging revealed a hypo-echoic lesion with turbulent arterial flow pattern on the lower left side of the uterus. Selective catheterization and subtraction angiography permitted diagnosis of a large pseudo-aneurysm of the left uterine artery. A selective embolization was performed. Recanalization of the embolized artery was confirmed 11 weeks after initial presentation, requiring repeat embolization. A planned caesarean section was performed at 34 weeks of gestation and a healthy boy was born with a birth weight of 2065 g. Conclusion Uterine artery pseudo-aneurysm is a rare but potentially life-threatening condition. It can be diagnosed using (doppler) ultrasound, revealing a hypoechoic mass with swirling blood flow. Angiography is the standard reference in diagnosing UAP and may provide definitive treatment. Management with selective unilateral uterine artery embolization appears to be safe in hemodynamically stable patients. It does not compromise uteroplacental circulation and may help to prolong the pregnancy, reducing morbidity associated with preterm birth.
Hypothesis of formation of pseudoaneurysm secondary to vascular injury during oocyte retrieval. A uterine artery pseudoaneurysm (UAP) should be considered in women with severe abdominal pain in pregnancy To our best knowledge, this is the first case report of UAP requiring repeat embolization during pregnancy
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Affiliation(s)
- Astrid Mulkers
- Department of Obstetrics and gynecology, University Hospital of Ghent, 9000 Ghent, Belgium
| | - Kathleen Podevyn
- Department of Obstetrics and Gynecology, Maria Middelares, 9000 Ghent, Belgium
| | - Isabelle Dehaene
- Department of Obstetrics and gynecology, University Hospital of Ghent, 9000 Ghent, Belgium
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12
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Van Coppenolle C, Jaillet L, Gallot D, Chabrot P, Delabaere A. [Rupture of an aneurism of the uterine artery during pregnancy treated by embolization]. ACTA ACUST UNITED AC 2019; 47:761-764. [PMID: 31493560 DOI: 10.1016/j.gofs.2019.08.006] [Citation(s) in RCA: 4] [Impact Index Per Article: 0.7] [Reference Citation Analysis] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 05/18/2019] [Indexed: 10/26/2022]
Affiliation(s)
- C Van Coppenolle
- Pôle femme et enfant, service de gynécologie- obstétrique, CHU de Clermont-Ferrand, 1, place Lucie et Raymond-Aubrac, 63003 Clermont-Ferrand cedex 1, France.
| | - L Jaillet
- Pôle femme et enfant, service de gynécologie- obstétrique, CHU de Clermont-Ferrand, 1, place Lucie et Raymond-Aubrac, 63003 Clermont-Ferrand cedex 1, France
| | - D Gallot
- Pôle femme et enfant, service de gynécologie- obstétrique, CHU de Clermont-Ferrand, 1, place Lucie et Raymond-Aubrac, 63003 Clermont-Ferrand cedex 1, France; Inserm, Équipe « Translational approach to epithelial injury and repair », CNRS, GRED, université Clermont Auvergne, 63000 Clermont-Ferrand, France
| | - P Chabrot
- Département de radiologie vasculaire, hôpital Gabriel-Montpied, CHU de Clermont-Ferrand, place Henri-Dunant, 63000 Clermont-Ferrand, France; CNRS, Sigma, Institut Pascal, université Clermont-Auvergne, CHU de Clermont-Ferrand, 63000 Clermont-Ferrand, France
| | - A Delabaere
- Pôle femme et enfant, service de gynécologie- obstétrique, CHU de Clermont-Ferrand, 1, place Lucie et Raymond-Aubrac, 63003 Clermont-Ferrand cedex 1, France; CNRS, Sigma, Institut Pascal, université Clermont-Auvergne, CHU de Clermont-Ferrand, 63000 Clermont-Ferrand, France
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