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Zhang Y, Zhang J, Liang C, Xu Y, Wu J, Wu J, Zhang Y, Jin A, Tan X, Luo L. Effect of crystalline lens decentration and tilt on visual performance in eyes implanted with bifocal or extended depth of focus intraocular lenses. BMC Ophthalmol 2025; 25:58. [PMID: 39901088 PMCID: PMC11792569 DOI: 10.1186/s12886-025-03884-5] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/19/2024] [Accepted: 01/22/2025] [Indexed: 02/05/2025] Open
Abstract
PURPOSE To explore the potential of crystalline lens decentration and tilt as indicators for screening cataract patients for presbyopia-correcting intraocular lens (IOL) implantation. METHODS Prospective observational study. Patients undergoing phacoemulsification with bifocal (Tecnis ZMB00) or extended depth-of-focus (EDOF) (Tecnis ZXR00) IOL implantation were consecutively enrolled. The decentration and tilt of the crystalline lens and the IOL were quantified through the utilization of swept-source optical coherence tomography (SS-OCT, Casia2). Postoperative visual acuity (VA), contrast sensitivity (CS), objective optical quality, and patient-reported outcomes were assessed at a 3-month follow-up. A LOWESS (LOcally WEighted Scatterplot Smoothing) curve was employed to analyze the changes in VA, CS, and objective optical quality relative to the decentration or tilt of crystalline lenses. A further comparison of visual outcomes was conducted based on the inflection points suggested by the curves. RESULTS Eighty‑seven patients with ZMB00 IOL and 76 patients with ZXR00 IOL were included. Multiple 6-mm internal aberrations showed a nonlinear increase with greater crystalline lens decentration. The inflection points for the steep increase were observed to be 0.28 mm for the bifocal group and 0.35 mm for the EDOF group. Beyond these points, internal aberrations such as coma increased significantly (all P < 0.01). Patient satisfaction decreased (P < 0.01). Moreover, the bifocal group exhibited a decline in spectacle-independence from 98.67% to 83.33% (P = 0.049), along with a reduction in CS (P < 0.05). CONCLUSIONS The increased decentration of crystalline lenses compromises specific visual quality aspects in eyes implanted with ZMB00 and ZXR00 IOLs, with cut-off values of 0.28 mm and 0.35 mm, respectively.
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Affiliation(s)
- Yu Zhang
- State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, China
- Sun Yat-Sen University of Medical Sciences, Guangzhou, China
| | - Jiaqing Zhang
- State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, China
| | - Chen Liang
- State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, China
| | - Yifan Xu
- State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, China
- Sun Yat-Sen University of Medical Sciences, Guangzhou, China
| | - Jiaying Wu
- Sun Yat-Sen University of Medical Sciences, Guangzhou, China
| | - Junming Wu
- Sun Yat-Sen University of Medical Sciences, Guangzhou, China
| | - Yifan Zhang
- State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, China
- Sun Yat-Sen University of Medical Sciences, Guangzhou, China
| | - Aixia Jin
- State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, China
- Sun Yat-Sen University of Medical Sciences, Guangzhou, China
| | - Xuhua Tan
- State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, China.
| | - Lixia Luo
- State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, China.
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Zhao Y, Yang F, Jiang Y, Tong W, Fang J, Zhao YE. Visual Outcomes and IOL Stability After Panoptix Trifocal Intraocular Lens Implantation in Eyes With High Myopia. J Refract Surg 2025; 41:e56-e64. [PMID: 39783812 DOI: 10.3928/1081597x-20241126-03] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 01/12/2025]
Abstract
PURPOSE To observe and explore the correlation between visual outcomes and intraocular lens (IOL) stability after tri-focal IOL implantation in eyes with high myopia. METHODS Patients with highly myopic cataract (axial length > 26 mm) were enrolled in this prospective study. Thirty-one eyes (31 patients) received implantation of a trifocal IOL (AcrySof IQ PanOptix TFNT00). Uncorrected distance, intermediate, and near visual acuity (UDVA 5 m, UIVA 60 cm, UNVA 40 cm) and refractive status were evaluated at 1 day, 1 week, 4 weeks, and 3 months postoperatively. The defocus curve was plotted 3 months postoperatively. The IOL tilt, IOL decentration, postoperative aqueous depth, and adhesion of the capsule with IOL were evaluated at 2 hours, 1 week, 4 weeks, and 3 months postoperatively. The correlation between postoperative visual outcomes and dynamic changes in IOL positioning was analyzed. RESULTS In total, 29 eyes of 29 patients were available for analysis. UDVA, UIVA, and UNVA were 0.03 ± 0.01, 0.03 ± 0.01, and 0.02 ± 0.01 logarithm of the minimum angle of resolution (logMAR) at 3 months postoperatively (mean spherical equivalent [SE]: -0.10 ± 0.04 D). From 1 to 7 days postoperatively, UIVA (P = .031) and UNVA (P = .02) improved, SE shifted to myopic (P = .001), and the IOL moved forward (P < .001). A bimodal defocus curve showed that the visual acuity achieved 0.2 logMAR from +0.50 to -2.50 D, and the peaks were at plano and -2.50 D, reaching 0.04 ± 0.01 and 0.08 ± 0.01 logMAR. The capsular bend index reached 3.35 ± 0.06 at 3 months postoperatively. There were no significant changes in tilt and decentration during the postoperative follow-up period. CONCLUSIONS This trifocal IOL provides excellent visual acuity at far, intermediate, and near distance in high myopia eyes. The postoperative position of the IOL was relatively stable in eyes with highly myopic cataracts. [J Refract Surg. 2025;41(1):e56-e64.].
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Du Y, Meng J, He W, Qi J, Lu Y, Zhu X. Complications of high myopia: An update from clinical manifestations to underlying mechanisms. ADVANCES IN OPHTHALMOLOGY PRACTICE AND RESEARCH 2024; 4:156-163. [PMID: 39036706 PMCID: PMC11260019 DOI: 10.1016/j.aopr.2024.06.003] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Subscribe] [Scholar Register] [Received: 03/07/2024] [Revised: 06/15/2024] [Accepted: 06/20/2024] [Indexed: 07/23/2024]
Abstract
Background High myopia is one of the major causes of visual impairment and has an ever-increasing prevalence, especially in East Asia. It is characterized by excessive axial elongation, leading to various blinding complications that extend beyond mere refractive errors and persist immovably after refractive surgery, presenting substantial public health challenge. Main text High myopia-related complications include lens pathologies, atrophic and tractional maculopathy, choroidal neovascularization, peripheral retinal degenerations and retinal detachment, and glaucoma and heightened susceptibility to intraocular pressure (IOP) elevation. Pathological lens changes characteristic of high myopia include early cataractogenesis, overgrowth of lens, weakened zonules, and postoperative capsular contraction syndrome, possibly driven by inflammatory pathogenesis, etc. Dome-shaped macula and cilioretinal arteries are two newly identified protective factors for central vision of highly myopic patients. These patients also face risks of open-angle glaucoma and IOP spike following intraocular surgery. Morphologic alternations of optic nerve in high myopia can complicate early glaucoma detection, necessitating comprehensive examinations and close follow-up. Anatomically, thinner trabecular meshwork increases this risk; conversely lamina cribrosa defects may offer a fluid outlet, potentially mitigating the pressure. Notably, anxiety has emerged as the first recognized extra-ocular complication in high myopia, with an underlying inflammatory pathogenesis that connects visual stimulus, blood and brain. Conclusions High myopia induces multiple ocular and potential mental health complications, underscoring the need to develop more effective strategies to improve both physical and emotional well-being of these patients, among which anti-inflammation might possibly represent a promising new target.
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Affiliation(s)
- Yu Du
- Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, China
- NHC Key Laboratory of Myopia and Related Eye Diseases, Key Laboratory of Myopia and Related Eye Diseases, Chinese Academy of Medical Sciences, Shanghai, China
- Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China
- State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China
| | - Jiaqi Meng
- Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, China
- NHC Key Laboratory of Myopia and Related Eye Diseases, Key Laboratory of Myopia and Related Eye Diseases, Chinese Academy of Medical Sciences, Shanghai, China
- Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China
- State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China
| | - Wenwen He
- Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, China
- NHC Key Laboratory of Myopia and Related Eye Diseases, Key Laboratory of Myopia and Related Eye Diseases, Chinese Academy of Medical Sciences, Shanghai, China
- Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China
- State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China
| | - Jiao Qi
- Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, China
- NHC Key Laboratory of Myopia and Related Eye Diseases, Key Laboratory of Myopia and Related Eye Diseases, Chinese Academy of Medical Sciences, Shanghai, China
- Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China
- State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China
| | - Yi Lu
- Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, China
- NHC Key Laboratory of Myopia and Related Eye Diseases, Key Laboratory of Myopia and Related Eye Diseases, Chinese Academy of Medical Sciences, Shanghai, China
- Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China
- State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China
| | - Xiangjia Zhu
- Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, China
- NHC Key Laboratory of Myopia and Related Eye Diseases, Key Laboratory of Myopia and Related Eye Diseases, Chinese Academy of Medical Sciences, Shanghai, China
- Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China
- State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China
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Yang YP, Tan Y, Liao Q. Analysis of visual quality improvement after implantation of PanOptix trifocal intraocular lens in cataract patients with different axial lengths. Am J Transl Res 2024; 16:2995-3004. [PMID: 39114707 PMCID: PMC11301498 DOI: 10.62347/frjz4885] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/20/2024] [Accepted: 05/28/2024] [Indexed: 08/10/2024]
Abstract
OBJECTIVE To assess the visual quality, both subjective and objective, of cataract patients with varying axial lengths (AL) after PanOptix trifocal intraocular lens (IOL) implantation and investigated the lens tilt and its correlation with visual outcomes. METHODS From July 2020 to June 2022, 70 patients (140 eyes) diagnosed with age-related cataracts and undergoing PanOptix implantation at Chongqing Eye and Vision Care Hospital, Aier Eye Hospital Group, were included. Patients were assigned to either the observation group (35 cases, 70 eyes with PanOptix trifocal IOL) or the control group (35 cases, 70 eyes with bifocal IOL). Patients were further subdivided based on AL into AL < 24 mm (observation group: 23 eyes; control group: 26 eyes) and AL ≥ 24 mm (observation group: 47 eyes; control group: 44 eyes). Postoperative follow-up lasted three months. Visual acuity (distant, intermediate, near), objective visual quality (Strehl ratio: SR, total eye modulation transfer function (MTF)), and visual aberrations were measured preoperatively and at 3 months post-operation. RESULTS Postoperatively, all groups saw significant improvements in uncorrected distance visual acuity (UCDVA), uncorrected intermediate visual acuity (UCIVA), and uncorrected near visual acuity (UCNVA) compared to preoperative values (T0) (all P < 0.05). Notably, UCIVA was significantly better in the observation group than in the control group (P < 0.05). At three months (T1), reductions in total high-order aberration (tHOA), internal high-order aberration (iHOA), coma, and trefoil aberrations were observed in both groups compared to baseline, with more significant decreases in the observation group (all P < 0.05). Both SR and MTF cutoff showed marked improvement from T0 to T1, with the observation group experiencing greater enhancements (both P < 0.05). The defocus curve of the observation group showed a gentle slope between +0.5 D and -3.0 D, maintaining superior visual acuity compared to the control group (P < 0.05). Subjective visual quality scores at T1 were significantly higher than at T0 for both groups (P < 0.05), with patients in the observation group scoring higher than those in the control group across all AL categories (P < 0.05). Spearman correlation analysis indicated that the tilt after PanOptix trifocal IOL implantation was associated with tHOA (r = 0.273, P = 0.022), iHOA (r = 0.433, P < 0.001), Trefoil (r = 0.360, P = 0.002) and coma (r = 0.688, P < 0.001). CONCLUSION PanOptix trifocal IOL implantation in cataract patients across different AL significantly enhances visual quality compared to bifocal IOLs, suggesting a strong case for its clinical adoption.
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Affiliation(s)
- Yin-Ping Yang
- Department of Cataract, Chongqing Eye and Vision Care Hospital·Aier Eye Hospital GroupChongqing 400000, China
| | - Ya Tan
- Department of Fundus Disease, Chongqing Eye and Vision Care Hospital·Aier Eye Hospital GroupChongqing 400000, China
| | - Qiong Liao
- Department of Cataract, Chongqing Eye and Vision Care Hospital·Aier Eye Hospital GroupChongqing 400000, China
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Wu YF, Tu RX, Zhang Y, Zhao XY, Qu J, Wang Y, Yu AY. Influence of Ocular Biometric Parameters on Intraocular Lens Position: A Prospective Cohort Study. J Refract Surg 2024; 40:e438-e444. [PMID: 39007810 DOI: 10.3928/1081597x-20240514-02] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 07/16/2024]
Abstract
PURPOSE To assess the influence of ocular biometric parameters on intraocular lens (IOL) tilt and decentration after cataract surgery. METHODS Patients scheduled for cataract surgery were screened for inclusion in this prospective cohort study. Tilt and decentration of the crystalline lens and IOL were measured using the CASIA2 (Tomey). Anterior chamber depth (ACD), lens thickness (LT), and axial length (AL) were preoperatively measured by the IOLMaster 700 (Carl Zeiss Meditec AG). Multivariate regression analysis was performed to assess the influence of ocular biometric parameters on IOL tilt and decentration after cataract surgery. RESULTS In total, 191 eyes of 120 patients were included. Age was positively correlated with IOL tilt, whereas ACD and AL were negatively correlated with IOL tilt. A strong positive correlation was found between preoperative crystalline lenses and postoperative IOLs in tilt magnitude (r = 0.769, P < .001) and tilt direction (r = 0.688, P < .001). A positive correlation was found between preoperative and postoperative lens decentration magnitude and decentration direction. Greater postoperative IOL tilt and decentration were significantly associated with greater preoperative crystalline lens tilt (P < .001) and decentration (P = .027). CONCLUSIONS IOL tilt was greater in older patients. Shorter AL and shallower ACD contributed to greater IOL tilt. The tilt and decentration of the IOL will be greater in patients with greater tilt and decentration of the crystalline lens. [J Refract Surg. 2024;40(7):e438-e444.].
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Li J, Sun B, Zhang Y, Hao Y, Wang Z, Liu C, Jiang S. Comparative efficacy and safety of all kinds of intraocular lenses in presbyopia-correcting cataract surgery: a systematic review and meta-analysis. BMC Ophthalmol 2024; 24:172. [PMID: 38627651 PMCID: PMC11020619 DOI: 10.1186/s12886-024-03446-1] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/13/2023] [Accepted: 04/10/2024] [Indexed: 04/19/2024] Open
Abstract
PURPOSE To assess the efficacy and safety of various intraocular lenses (IOLs), including standard monofocal, bifocal, trifocal, extended depth of focus (EDOF), and enhanced monofocal IOLs, post-cataract surgery through a network meta-analysis. METHODS A systematic search of PubMed, Cochrane Library, and Web of Science was conducted to identify relevant studies from the past 5 years. Parameters such as binocular visual acuities, spectacle independence, contrast sensitivity (CS), and optical quality were used to evaluate efficacy and safety. Data from the selected studies were analyzed using Review Manager 5.4 and STATA 17.0 software. RESULTS Twenty-eight Randomized Controlled Trials (RCTs) comprising 2465 subjects were included. Trifocal IOLs exhibited superior uncorrected near visual acuity (UNVA) compared to monofocal IOLs (MD: -0.35; 95% CI: -0.48, -0.22). Both trifocal (AcrySof IQ PanOptix IOLs group MD: -0.13; 95% CI: -0.21, -0.06) and EDOF IOLs (MD: -0.13; 95% CI: -0.17, -0.09) showed better uncorrected intermediate visual acuity (UIVA) than monofocal IOLs. Trifocal IOLs ranked highest in spectacle independence at various distances (AT LISAtri 839MP group: SUCRA 97.5% for distance, 80.7% for intermediate; AcrySof IQ PanOptix group: SUCRA 83.0% for near). CONCLUSIONS For cataract patients who want to treat presbyopia, trifocal IOLs demonstrated better visual acuity and spectacle independence at near distances. Different types of trifocal IOL characteristics differ. EDOF and enhanced monofocal IOLs have improved visual quality at intermediate distances.Therefore, It is very important to select the appropriate IOLs based on the lens characteristics and patient needs.
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Affiliation(s)
- Jinyu Li
- Department of Ophthalmology, Yantai Affiliated Hospital of Binzhou Medical University, Binzhou Medical University, Jinbu Street, Muping area, Yantai, Shandong Province, 264000, China
| | - Bin Sun
- Department of Ophthalmology, Yantai Affiliated Hospital of Binzhou Medical University, Binzhou Medical University, Jinbu Street, Muping area, Yantai, Shandong Province, 264000, China
| | - Yuexin Zhang
- Department of Ophthalmology, Yantai Affiliated Hospital of Binzhou Medical University, Binzhou Medical University, Jinbu Street, Muping area, Yantai, Shandong Province, 264000, China
| | - Yansong Hao
- Department of Ophthalmology, Yantai Affiliated Hospital of Binzhou Medical University, Binzhou Medical University, Jinbu Street, Muping area, Yantai, Shandong Province, 264000, China
| | - Ze Wang
- Department of Ophthalmology, Shijiazhuang People's Hospital, Shi Jiazhuang, 050200, China
| | - Chengjiang Liu
- Department of General Medicine, Affiliated Anqing First People's Hospital of Anhui Medical University, Anhui, 246000, China
| | - Shanhao Jiang
- Department of Ophthalmology, Yantai Affiliated Hospital of Binzhou Medical University, Binzhou Medical University, Jinbu Street, Muping area, Yantai, Shandong Province, 264000, China.
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Liu X, Wu W, Huang Y, Fu Y, Huang Y, Li Q. Repeatability of Pentacam-derived intraocular lens decentration measurements and the level of agreement with OPD-Scan III: A prospective observational case series. PLoS One 2024; 19:e0299064. [PMID: 38517869 PMCID: PMC10959365 DOI: 10.1371/journal.pone.0299064] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/05/2023] [Accepted: 01/03/2024] [Indexed: 03/24/2024] Open
Abstract
PURPOSE This study aimed to assess the repeatability of intraocular lens (IOL) decentration measurements obtained through Pentacam, based on corneal topographic axis (CTA) and pupillary axis (PA), and to evaluate the level of agreement between Pentacam and OPD-Scan III devices in measuring IOL decentration. METHODS In this prospective observational case series, three measurements were performed with Pentacam to evaluate the repeatability of the measurements. The analysis included the calculation of the mean and standard deviations (SD), conducting a repeated measures analysis of variance (rANOVA), and determining an intraclass correlation coefficient (ICC) to assess the repeatability of the measurements. Moreover, Bland-Altman analysis was employed to assess the agreement between Pentacam and OPD-Scan III devices in measuring IOL decentration. IOL decentration measurements were obtained with respect to both CTA and PA. RESULTS A total of 40 eyes from 40 patients were analyzed. The rANOVA revealed no significant difference among three consecutive measurements of IOL decentration obtained with Pentacam. The mean SD of all parameters ranged from 0.04 mm to 0.07 mm. With CTA as the reference axis, the ICC values for Pentacam measurements of IOL decentration were 0.82 mm for the X-axis, 0.76 mm for the Y-axis, and 0.82 mm for spatial distance. When using PA as the reference axis, the corresponding ICC values were 0.87, 0.89, and 0.77, respectively. The 95% limits of agreement for all IOL decentration measurements were wide when comparing Pentacam and OPD-Scan III. CONCLUSIONS Pentacam demonstrated high repeatability in measuring IOL decentration with respect to both CTA and PA. However, due to poor agreement between Pentacam and OPD-Scan III measurements, caution should be exercised when using data interchangeably between the two devices.
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Affiliation(s)
- Xiaobao Liu
- Shengli Clinical Medical College of Fujian Medical University; Fujian Medical University, Fuzhou, China
| | - Wenjie Wu
- Shengli Clinical Medical College of Fujian Medical University; Fujian Medical University, Fuzhou, China
- Department of Ophthalmology, Fujian Provincial Hospital, Fuzhou, China
| | - Yulong Huang
- Shengli Clinical Medical College of Fujian Medical University; Fujian Medical University, Fuzhou, China
| | - Yabo Fu
- Shengli Clinical Medical College of Fujian Medical University; Fujian Medical University, Fuzhou, China
- Department of Ophthalmology, Longyan People Hospital of Fujian, Longyan, China
| | - Yue Huang
- Shengli Clinical Medical College of Fujian Medical University; Fujian Medical University, Fuzhou, China
| | - Qiong Li
- Shengli Clinical Medical College of Fujian Medical University; Fujian Medical University, Fuzhou, China
- Department of Ophthalmology, Fujian Provincial Hospital, Fuzhou, China
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Chen X, Lin IC, Miao H, Cheng M, Li B, Jiang Y, Lei Y, Wang X, Zhou X. Effects of Decentration of Implantable Collamer Lens V4c on Visual Quality With the OPD-Scan III Aberrometer. Am J Ophthalmol 2024; 259:88-95. [PMID: 37952651 DOI: 10.1016/j.ajo.2023.11.008] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 06/27/2023] [Revised: 11/04/2023] [Accepted: 11/05/2023] [Indexed: 11/14/2023]
Abstract
PURPOSE This study aimed to analyze the relationship between visual quality and implantable collamer lenses (ICL) decentration. DESIGN Prospective treatment evaluation clinical study METHODS: This prospective study included 119 eyes with ICL implantation. Refractive parameters and ocular aberrations were examined pre- and postoperatively. ICL decentration and higher-order aberrations (HOAs) were evaluated using the OPD-Scan III aberrometer. RESULTS At the 1-month follow-up, the mean values for decentration were 0.38 ± 0.19 mm (0.02-0.78). Regarding the position of decentration in right and left eyes, 22.8% and 17.7% were located in the superior nasal section, 0% and 6.5% in the inferior nasal section, 50.9% and 53.2% in the superior temporal section, and 26.3% and 22.6% in the inferior temporal section, respectively. The root mean square values of whole-eye total HOAs, coma, and trefoil had significantly increased. Decentration had a significant negative correlation with variation in the pre- and postoperative trefoils of the whole eye. CONCLUSIONS ICL decentration had a slightly negative correlation with trefoil and slightly affected visual quality.
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Affiliation(s)
- Xun Chen
- From the Fudan University Eye Ear Nose and Throat Hospital (X.C., I.-C.L., H.M., M.C., B.L., Y.J., Y.L., X.W., X.Z.), Shanghai, China; National Health Commission Key Lab of Myopia (Fudan University) (X.C., I.-C.L., H.M., M.C., B.L., Y.J., Y.L., X.W., X.Z.), Shanghai, China; Shanghai Research Center of Ophthalmology and Optometry (X.C., I.-C.L., H.M., M.C., B.L., Y.J., Y.L., X.W., X.Z.), Shanghai, China; Shanghai Engineering Research Center of Laser and Autostereoscopic 3D for Vision Care (20DZ2255000) (X.C., I.-C.L., H.M., M.C., B.L., Y.J., Y.L., X.W., X.Z.), Shanghai, China
| | - I-Chun Lin
- From the Fudan University Eye Ear Nose and Throat Hospital (X.C., I.-C.L., H.M., M.C., B.L., Y.J., Y.L., X.W., X.Z.), Shanghai, China; National Health Commission Key Lab of Myopia (Fudan University) (X.C., I.-C.L., H.M., M.C., B.L., Y.J., Y.L., X.W., X.Z.), Shanghai, China; Shanghai Research Center of Ophthalmology and Optometry (X.C., I.-C.L., H.M., M.C., B.L., Y.J., Y.L., X.W., X.Z.), Shanghai, China; Shanghai Engineering Research Center of Laser and Autostereoscopic 3D for Vision Care (20DZ2255000) (X.C., I.-C.L., H.M., M.C., B.L., Y.J., Y.L., X.W., X.Z.), Shanghai, China
| | - Huamao Miao
- From the Fudan University Eye Ear Nose and Throat Hospital (X.C., I.-C.L., H.M., M.C., B.L., Y.J., Y.L., X.W., X.Z.), Shanghai, China; National Health Commission Key Lab of Myopia (Fudan University) (X.C., I.-C.L., H.M., M.C., B.L., Y.J., Y.L., X.W., X.Z.), Shanghai, China; Shanghai Research Center of Ophthalmology and Optometry (X.C., I.-C.L., H.M., M.C., B.L., Y.J., Y.L., X.W., X.Z.), Shanghai, China; Shanghai Engineering Research Center of Laser and Autostereoscopic 3D for Vision Care (20DZ2255000) (X.C., I.-C.L., H.M., M.C., B.L., Y.J., Y.L., X.W., X.Z.), Shanghai, China
| | - Mingrui Cheng
- From the Fudan University Eye Ear Nose and Throat Hospital (X.C., I.-C.L., H.M., M.C., B.L., Y.J., Y.L., X.W., X.Z.), Shanghai, China; National Health Commission Key Lab of Myopia (Fudan University) (X.C., I.-C.L., H.M., M.C., B.L., Y.J., Y.L., X.W., X.Z.), Shanghai, China; Shanghai Research Center of Ophthalmology and Optometry (X.C., I.-C.L., H.M., M.C., B.L., Y.J., Y.L., X.W., X.Z.), Shanghai, China; Shanghai Engineering Research Center of Laser and Autostereoscopic 3D for Vision Care (20DZ2255000) (X.C., I.-C.L., H.M., M.C., B.L., Y.J., Y.L., X.W., X.Z.), Shanghai, China
| | - Boliang Li
- From the Fudan University Eye Ear Nose and Throat Hospital (X.C., I.-C.L., H.M., M.C., B.L., Y.J., Y.L., X.W., X.Z.), Shanghai, China; National Health Commission Key Lab of Myopia (Fudan University) (X.C., I.-C.L., H.M., M.C., B.L., Y.J., Y.L., X.W., X.Z.), Shanghai, China; Shanghai Research Center of Ophthalmology and Optometry (X.C., I.-C.L., H.M., M.C., B.L., Y.J., Y.L., X.W., X.Z.), Shanghai, China; Shanghai Engineering Research Center of Laser and Autostereoscopic 3D for Vision Care (20DZ2255000) (X.C., I.-C.L., H.M., M.C., B.L., Y.J., Y.L., X.W., X.Z.), Shanghai, China
| | - Yinjie Jiang
- From the Fudan University Eye Ear Nose and Throat Hospital (X.C., I.-C.L., H.M., M.C., B.L., Y.J., Y.L., X.W., X.Z.), Shanghai, China; National Health Commission Key Lab of Myopia (Fudan University) (X.C., I.-C.L., H.M., M.C., B.L., Y.J., Y.L., X.W., X.Z.), Shanghai, China; Shanghai Research Center of Ophthalmology and Optometry (X.C., I.-C.L., H.M., M.C., B.L., Y.J., Y.L., X.W., X.Z.), Shanghai, China; Shanghai Engineering Research Center of Laser and Autostereoscopic 3D for Vision Care (20DZ2255000) (X.C., I.-C.L., H.M., M.C., B.L., Y.J., Y.L., X.W., X.Z.), Shanghai, China
| | - Yadi Lei
- From the Fudan University Eye Ear Nose and Throat Hospital (X.C., I.-C.L., H.M., M.C., B.L., Y.J., Y.L., X.W., X.Z.), Shanghai, China; National Health Commission Key Lab of Myopia (Fudan University) (X.C., I.-C.L., H.M., M.C., B.L., Y.J., Y.L., X.W., X.Z.), Shanghai, China; Shanghai Research Center of Ophthalmology and Optometry (X.C., I.-C.L., H.M., M.C., B.L., Y.J., Y.L., X.W., X.Z.), Shanghai, China; Shanghai Engineering Research Center of Laser and Autostereoscopic 3D for Vision Care (20DZ2255000) (X.C., I.-C.L., H.M., M.C., B.L., Y.J., Y.L., X.W., X.Z.), Shanghai, China
| | - Xiaoying Wang
- From the Fudan University Eye Ear Nose and Throat Hospital (X.C., I.-C.L., H.M., M.C., B.L., Y.J., Y.L., X.W., X.Z.), Shanghai, China; National Health Commission Key Lab of Myopia (Fudan University) (X.C., I.-C.L., H.M., M.C., B.L., Y.J., Y.L., X.W., X.Z.), Shanghai, China; Shanghai Research Center of Ophthalmology and Optometry (X.C., I.-C.L., H.M., M.C., B.L., Y.J., Y.L., X.W., X.Z.), Shanghai, China; Shanghai Engineering Research Center of Laser and Autostereoscopic 3D for Vision Care (20DZ2255000) (X.C., I.-C.L., H.M., M.C., B.L., Y.J., Y.L., X.W., X.Z.), Shanghai, China.
| | - Xingtao Zhou
- From the Fudan University Eye Ear Nose and Throat Hospital (X.C., I.-C.L., H.M., M.C., B.L., Y.J., Y.L., X.W., X.Z.), Shanghai, China; National Health Commission Key Lab of Myopia (Fudan University) (X.C., I.-C.L., H.M., M.C., B.L., Y.J., Y.L., X.W., X.Z.), Shanghai, China; Shanghai Research Center of Ophthalmology and Optometry (X.C., I.-C.L., H.M., M.C., B.L., Y.J., Y.L., X.W., X.Z.), Shanghai, China; Shanghai Engineering Research Center of Laser and Autostereoscopic 3D for Vision Care (20DZ2255000) (X.C., I.-C.L., H.M., M.C., B.L., Y.J., Y.L., X.W., X.Z.), Shanghai, China
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9
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Alfonso JF, Fernández-Vega-Cueto L, Lisa C, Alfonso-Bartolozzi B, Palacios A, Madrid-Costa D. Clinical and Aberrometric Outcomes of a New Implantable Collamer Lens for Myopia and Presbyopia Correction in Phakic Patients. J Refract Surg 2023; 39:589-596. [PMID: 37675906 DOI: 10.3928/1081597x-20230726-02] [Citation(s) in RCA: 1] [Impact Index Per Article: 0.5] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 09/08/2023]
Abstract
PURPOSE To assess the clinical and aberrometric outcomes of a new Implantable Collamer Lens (EVO Viva ICL; STAAR Surgical) to correct moderate to high myopia and presbyopia. METHODS The study included 80 eyes of 40 patients who had bilateral EVO Viva ICL implantation. Uncorrected (UDVA) and corrected (CDVA) distance visual acuities, refraction, presbyopic add power, binocular through-focus visual acuity, total ocular spherical aberration (SA), coma aberration, and root mean square of ocular higher order aberrations (RMS HOAs) (i-Trace Aberrometer; Tracey Technologies) for a 4.5-mm pupil size were evaluated. RESULTS The mean binocular postoperative UDVA and CDVA were 0.09 ± 0.19 and 0.02 ± 0.03 logMAR, respectively. The postoperative spherical equivalent was -0.61 ± 0.54 diopters (D). The presbyopic add power reduced from +1.31 ± 0.74 D preoperatively to +0.44 ± 0.58 D after surgery (P < .0001). The mean visual acuity was 0.1 logMAR or better (20/25 or better) across the vergence range from +0.50 to -1.50 D, better than 0.2 logMAR (20/32 or better) up to the vergence of -2.00 D, and remained better than 0.3 logMAR (20/40 or better) up to the vergence of -2.50 D. The total ocular aberrations induced by EVO Viva ICL were -0.34 ± 0.09 µm of SA, 0.24 ± 0.18 µm of coma, and 0.26 ± 0.12 µm of RMS HOAs. CONCLUSIONS The outcomes support that the new ICL might be a good alternative for myopia and presbyopia correction in patients aged between 45 and 55 years. Further studies are needed to evaluate the threshold lens misalignment from which the patient´s visual quality would be affected. [J Refract Surg. 2023;39(9):589-596.].
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10
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Tabuchi H, Tanabe H, Shirakami T, Takase K, Shojo T, Yamauchi T. Comparison of visual performance between bifocal and extended-depth-of-focus intraocular lenses. PLoS One 2023; 18:e0288602. [PMID: 37440544 DOI: 10.1371/journal.pone.0288602] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/18/2022] [Accepted: 07/02/2023] [Indexed: 07/15/2023] Open
Abstract
We compared the visual performance of a bifocal intraocular lens (IOL) (ZMB00) and an extended-depth-of-focus (EDOF) IOL (ZXR00V) by evaluating postoperative parameters at 10 weeks after the last surgery in cataract patients who underwent bilateral ZMB00 or ZXR00V implantation between 2011 and 2020. The right and left lenses were implanted within 3 months of each other. The study enrolled 1536 eyes of 768 patients; the ZMB00 group comprised 1326 eyes of 663 patients (age: 67.0 ± 7.8 years; female/male, 518/145), and the ZXR00V group comprised 210 eyes of 105 patients (age: 67.8 ± 6.9 years; female/male, 39/66). A linear mixed-effects model using data for both eyes, with strict adjustments for sex, age, subjective refraction spherical equivalent, subjective refraction cylinder, corneal astigmatism, axial length, corneal higher-order aberrations and pupil diameter, ensured statistical validity. Uncorrected near visual acuity, corrected near visual acuity, and near spectacle independence were significantly better in the ZMB00 group (p<0.00068, Wald test) than in the ZXR00V group. Contrast sensitivity (visual angle of the test target: 4.0°/2.5°/1.6°/1.0°/0.7°) and contrast sensitivity with glare (4.0°/2.5°/1.6°/1.0°/0.7°) were significantly better in the ZXR00V group (p<0.00068, Wald test) than in the ZMB00 group. Uncorrected intermediate visual acuity, contrast sensitivity with glare (6.3°), and 25-item National Eye Institute Visual Function Questionnaire (VFQ-25) scores for General Vision were slightly but significantly better in the ZXR00V group than in the ZMB00 group (p<0.05, Wald test). At high-performance levels, the two IOL groups had different characteristics regarding various visual performance parameters.
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Affiliation(s)
- Hitoshi Tabuchi
- Department of Ophthalmology, Tsukazaki Hospital, Himeji, Japan
- Department of Technology and Design Thinking for Medicine, Hiroshima University Graduate School of Biomedical and Health Sciences, Hiroshima, Japan
| | - Hirotaka Tanabe
- Department of Ophthalmology, Tsukazaki Hospital, Himeji, Japan
| | | | - Kosuke Takase
- Department of Ophthalmology, Tsukazaki Hospital, Himeji, Japan
| | - Tomohiro Shojo
- Department of Ophthalmology, Tsukazaki Hospital, Himeji, Japan
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11
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Niu L, Zhang Z, Miao H, Zhao J, Wang X, He JC, Zhou X. Effects of lighting conditions and accommodation on the three-dimensional position of Visian implantable collamer lens. EYE AND VISION (LONDON, ENGLAND) 2022; 9:42. [PMID: 36329521 PMCID: PMC9635130 DOI: 10.1186/s40662-022-00313-2] [Citation(s) in RCA: 2] [Impact Index Per Article: 0.7] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Subscribe] [Scholar Register] [Received: 04/15/2022] [Accepted: 10/13/2022] [Indexed: 11/06/2022]
Abstract
Background To investigate the effects of lighting conditions and accommodation on the three-dimensional position of Visian implantable collamer lens (ICL V4c). Methods This observational study recruited 62 eyes of 31 myopia patients underwent ICL V4c implantation. Anterior segment optical coherence tomography (AS-OCT) assessed the anterior chamber depth (ACD), ACD-ICL (distance from the corneal endothelium to anterior surface of the ICL V4c), vault (distance between the posterior ICL V4c surface and anterior crystalline lens surface), and crystalline lens tilt under various lighting conditions and accommodation relative to the corneal topographic axis at one year after ICL V4c implantation. Baseline was defined as the scotopic condition, which was also the non-accommodative stimulus condition. The ICL V4c tilt was analyzed using MATLAB. The significance level was set at P < 0.05. Results The ACD-ICL values were similar under various lighting conditions (P = 0.978) but decreased during accommodation (P < 0.001). The vault was significantly smaller under mesopic and photopic conditions than the baseline (P = 0.044 and P < 0.001, respectively) but remained unchanged during accommodation (P = 0.058). The inferotemporal proportion of ICL V4c (88.7%, 55 eyes) and crystalline lens (74.2%, 46 eyes) tilts were not significantly different (P = 0.063). Crystalline lens under various lighting conditions and accommodation exhibited similar tilts. The vertical tilt of ICL V4c was significantly larger under photopic conditions than the baseline (P = 0.038). The horizontal and total tilts were significantly decreased during accommodation (P = 0.043 and 0.013, respectively). Conclusions The axial position of ICL V4c in the anterior chamber was stable under various lighting conditions. Lighting conditions and accommodation may influence vertical, horizontal and total tilts of ICL V4c. Supplementary Information The online version contains supplementary material available at 10.1186/s40662-022-00313-2.
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Affiliation(s)
- Lingling Niu
- Department of Ophthalmology and Optometry, Eye & ENT Hospital, Fudan University, Shanghai, China.,NHC Key Laboratory of Myopia (Fudan University), Shanghai, China.,Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China.,Shanghai Research Center of Ophthalmology and Optometry, Shanghai, China
| | - Zhe Zhang
- Department of Ophthalmology and Optometry, Eye & ENT Hospital, Fudan University, Shanghai, China.,NHC Key Laboratory of Myopia (Fudan University), Shanghai, China.,Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China.,Shanghai Research Center of Ophthalmology and Optometry, Shanghai, China
| | - Huamao Miao
- Department of Ophthalmology and Optometry, Eye & ENT Hospital, Fudan University, Shanghai, China.,NHC Key Laboratory of Myopia (Fudan University), Shanghai, China.,Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China.,Shanghai Research Center of Ophthalmology and Optometry, Shanghai, China
| | - Jing Zhao
- Department of Ophthalmology and Optometry, Eye & ENT Hospital, Fudan University, Shanghai, China.,NHC Key Laboratory of Myopia (Fudan University), Shanghai, China.,Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China.,Shanghai Research Center of Ophthalmology and Optometry, Shanghai, China
| | - Xiaoying Wang
- Department of Ophthalmology and Optometry, Eye & ENT Hospital, Fudan University, Shanghai, China.,NHC Key Laboratory of Myopia (Fudan University), Shanghai, China.,Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China.,Shanghai Research Center of Ophthalmology and Optometry, Shanghai, China
| | - Ji C He
- New England College of Optometry, MA, Boston, USA.
| | - Xingtao Zhou
- Department of Ophthalmology and Optometry, Eye & ENT Hospital, Fudan University, Shanghai, China. .,NHC Key Laboratory of Myopia (Fudan University), Shanghai, China. .,Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China. .,Shanghai Research Center of Ophthalmology and Optometry, Shanghai, China.
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12
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Influence of ocular biometric parameters such as effective lens position, keratometry, and axial length on near add power of multifocal intraocular lens. J Cataract Refract Surg 2022; 48:1331-1334. [PMID: 35405733 DOI: 10.1097/j.jcrs.0000000000000947] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/07/2021] [Accepted: 03/22/2022] [Indexed: 11/25/2022]
Abstract
Visual quality after multifocal intraocular lens (mIOL) implantation has received increased attention. Postoperative residual ametropia, posterior capsule opacification, dry eye, IOL decentration, pupil size, and other factors can affect patient visual acuity. In addition, patient dissatisfaction after mIOL implantation has a relationship with the near add power of mIOLs, which is correlated with vision habits of different patients. Indeed, the actual spectacle plane add power of mIOLs is incompletely consistent with the near add power given by the manufacturers. Ocular biometric parameters such as effective lens position, keratometry, and axial length have effect on the near add power of mIOLs in the lens plane. In this article, the influence of ocular biometric eye parameters on the actual near add power of mIOLs in the lens plane was reviewed.
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13
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Niu L, Zhang Z, Miao H, Zhao J, Li M, He JC, Yao P, Zhou X. Effects of tilt and decentration of Visian Implantable Collamer Lens (ICL V4c) on visual quality: an observational study. BMC Ophthalmol 2022; 22:294. [PMID: 35790941 PMCID: PMC9254425 DOI: 10.1186/s12886-022-02499-4] [Citation(s) in RCA: 8] [Impact Index Per Article: 2.7] [Reference Citation Analysis] [Abstract] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/23/2022] [Accepted: 06/17/2022] [Indexed: 01/19/2023] Open
Abstract
Background The central hole of the Visian Implantable Collamer Lens (ICL V4c) provides a reference to observe its tilt or decentration. This study aimed to investigate the tilt and decentration effects of ICL V4c on visual quality after implantation. Methods A total of 135 eyes from 69 patients who underwent ICL V4c implantation were included in this study. Evaluation of uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), and aberrations were performed 6-months postoperatively. The anterior segment parameters were collected using CASIA2 anterior segment-optical coherence tomography, tilt and decentration of ICL V4c were analyzed using MATLAB software. All patients received questionnaires to investigate the visual quality postoperatively. Results The safety and effectiveness were 1.18 ± 0.17 and 1.11 ± 0.18, respectively. No significant changes were observed regarding higher-order and spherical aberrations after the operation; however, coma and trefoil significantly increased compared to preoperative values. The average total decentration and tilt was 0.21 ± 0.12 mm and 2.54 ± 1.00°, respectively. Horizontal, vertical, and total values of tilt and decentration were not significantly associated with postoperative CDVA, UDVA, and aberrations. The most common visual symptom was halo, and 97.04% of patients had a satisfaction score ≥ 8. The total or horizontal tilt was significantly positively correlated with the frequency, severity, and bothersome scores from the questionnaires. Conclusions ICL V4c implantation can obtain high visual quality and patient satisfaction. Although the degree of tilt and decentration after ICL V4c implantation was small, a positive effect on subjective visual quality was observed. Supplementary Information The online version contains supplementary material available at 10.1186/s12886-022-02499-4.
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Xu J, Lin P, Zhang S, Lu Y, Zheng T. Risk factors associated with intraocular lens decentration after cataract surgery. Am J Ophthalmol 2022; 242:88-95. [PMID: 35594914 DOI: 10.1016/j.ajo.2022.05.005] [Citation(s) in RCA: 7] [Impact Index Per Article: 2.3] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/17/2022] [Revised: 04/22/2022] [Accepted: 05/11/2022] [Indexed: 11/30/2022]
Abstract
PURPOSE To identify risk factors associated with intraocular lens (IOL) decentration after uneventful phacoemulsification with IOL implantation. DESIGN A prospective cohort study METHODS: All patients underwent a general ophthalmologic examination. One month postoperatively, the magnitude and orientation of IOL decentration relative to the visual axis center were assessed using an OPD-Scan III aberrometer, and the vertical and horizontal decentration values were determined. Univariate and multivariate linear regression analyses were performed to evaluate the association between the IOL decentration and ocular biometric parameters. RESULTS In total, 143 eyes of 143 patients were enrolled. The mean decentration magnitude was 0.27±0.15 mm, and the decentration axis appeared at any orientation, with no orientation tendency. The horizontal and vertical decentration were -0.02±0.22 mm and 0.01±0.22 mm, respectively. Multivariate regression analysis showed that the white-to-white distance (WTW) and the magnitude of angle α were positively associated with the decentration magnitude (P<0.001, adj. R2=0.121), the horizontal angle κ and horizontal angle α were positively associated with the horizontal decentration (P<0.001, adj. R2=0.209), and the anterior chamber depth (ACD) and vertical angle κ were positively associated with the vertical decentration (P<0.001, adj. R2=0.152). CONCLUSIONS The IOL decentration magnitude was greater in patients with a larger WTW and a larger angle α, the horizontal decentration was greater in patients with a larger horizontal angle κ and a larger horizontal angle α, and the vertical decentration was greater in patients with a deeper ACD and a larger vertical angle κ. In these patients, premium IOLs should be implanted cautiously.
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Affiliation(s)
- Jie Xu
- From the Department of Ophthalmology (J.X., P.M.L., S.H.Z., Y.L., T.Y.Z.), Eye and ENT Hospital, Fudan University, Shanghai, China; Eye Institute (J.X., P.M.L., S.H.Z., Y.L., T.Y.Z.), Eye and ENT Hospital , Fudan University, Shanghai, China; Key Laboratory of Myopia, Ministry of Health (J.X., P.M.L., S.H.Z., Y.L., T.Y.Z.), Shanghai, China; Shanghai Key Laboratory of Visual Impairment and Restoration (J.X., P.M.L., S.H.Z., Y.L., T.Y.Z.), Shanghai, China
| | - Peimin Lin
- From the Department of Ophthalmology (J.X., P.M.L., S.H.Z., Y.L., T.Y.Z.), Eye and ENT Hospital, Fudan University, Shanghai, China; Eye Institute (J.X., P.M.L., S.H.Z., Y.L., T.Y.Z.), Eye and ENT Hospital , Fudan University, Shanghai, China; Key Laboratory of Myopia, Ministry of Health (J.X., P.M.L., S.H.Z., Y.L., T.Y.Z.), Shanghai, China; Shanghai Key Laboratory of Visual Impairment and Restoration (J.X., P.M.L., S.H.Z., Y.L., T.Y.Z.), Shanghai, China
| | - Shaohua Zhang
- From the Department of Ophthalmology (J.X., P.M.L., S.H.Z., Y.L., T.Y.Z.), Eye and ENT Hospital, Fudan University, Shanghai, China; Eye Institute (J.X., P.M.L., S.H.Z., Y.L., T.Y.Z.), Eye and ENT Hospital , Fudan University, Shanghai, China; Key Laboratory of Myopia, Ministry of Health (J.X., P.M.L., S.H.Z., Y.L., T.Y.Z.), Shanghai, China; Shanghai Key Laboratory of Visual Impairment and Restoration (J.X., P.M.L., S.H.Z., Y.L., T.Y.Z.), Shanghai, China
| | - Yi Lu
- From the Department of Ophthalmology (J.X., P.M.L., S.H.Z., Y.L., T.Y.Z.), Eye and ENT Hospital, Fudan University, Shanghai, China; Eye Institute (J.X., P.M.L., S.H.Z., Y.L., T.Y.Z.), Eye and ENT Hospital , Fudan University, Shanghai, China; Key Laboratory of Myopia, Ministry of Health (J.X., P.M.L., S.H.Z., Y.L., T.Y.Z.), Shanghai, China; Shanghai Key Laboratory of Visual Impairment and Restoration (J.X., P.M.L., S.H.Z., Y.L., T.Y.Z.), Shanghai, China.
| | - Tianyu Zheng
- From the Department of Ophthalmology (J.X., P.M.L., S.H.Z., Y.L., T.Y.Z.), Eye and ENT Hospital, Fudan University, Shanghai, China; Eye Institute (J.X., P.M.L., S.H.Z., Y.L., T.Y.Z.), Eye and ENT Hospital , Fudan University, Shanghai, China; Key Laboratory of Myopia, Ministry of Health (J.X., P.M.L., S.H.Z., Y.L., T.Y.Z.), Shanghai, China; Shanghai Key Laboratory of Visual Impairment and Restoration (J.X., P.M.L., S.H.Z., Y.L., T.Y.Z.), Shanghai, China.
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15
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Chen XY, Wang YC, Zhao TY, Wang ZZ, Wang W. Tilt and decentration with various intraocular lenses: A narrative review. World J Clin Cases 2022; 10:3639-3646. [PMID: 35647149 PMCID: PMC9100733 DOI: 10.12998/wjcc.v10.i12.3639] [Citation(s) in RCA: 23] [Impact Index Per Article: 7.7] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 08/09/2021] [Revised: 12/23/2021] [Accepted: 03/06/2022] [Indexed: 02/06/2023] Open
Abstract
We find that tilt and decentration of intraocular lens (IOL) commonly cause visual quality deterioration after cataract surgery. Multiple factors affect IOL tilt and decentration in the pre-, mid-, and post-operation phases. Moreover, the tilt and decentration of 1-piece IOL are less correlated with internal ocular HOAs than those of 3-piece IOL. Aspherical IOLs are more sensitive to decentration or tilt than spherical IOLs. Furthermore, the optical performance of toric IOLs with an accurate axis remains stable irrespective of tilt and decentration. The optical quality of asymmetric multifocal IOLs varies significantly after decentration and tilt in different directions. The image quality enhances or deteriorates in the direction of the decentered IOL. An extended depth of focus IOL can achieve good visual acuity in the distant, intermediate, and near range. Additionally, its tilt and decentration have less impact on the vision than bifocal and trifocal IOL. This is the first review that compares the effect of IOL tilt and decentration on image quality for various IOL designs. The result indicates that a deeper understanding of tilt and decentration of various IOLs can help achieve a better visual effect to visually improve refractive cataract surgery.
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Affiliation(s)
- Xiao-Yong Chen
- Department of Ophthalmology, Peking University The Third Hospital, Beijing 100191, China
| | - Yu-Chen Wang
- Department of Ophthalmology, Peking University The Third Hospital, Beijing 100191, China
| | - Tian-Yao Zhao
- Department of Ophthalmology, Peking University The Third Hospital, Beijing 100191, China
| | - Zi-Zhen Wang
- Department of Ophthalmology, Peking University The Third Hospital, Beijing 100191, China
| | - Wei Wang
- Department of Ophthalmology, Peking University The Third Hospital, Beijing 100191, China
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16
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Chen ZX, Zhao ZN, Sun Y, Jia WN, Zheng JL, Chen JH, Chen TH, Lan LN, Jiang YX. Phacoemulsification Combined With Supra-Capsular and Scleral-Fixated Intraocular Lens Implantation in Microspherophakia: A Retrospective Comparative Study. Front Med (Lausanne) 2022; 9:869539. [PMID: 35492301 PMCID: PMC9047048 DOI: 10.3389/fmed.2022.869539] [Citation(s) in RCA: 1] [Impact Index Per Article: 0.3] [Reference Citation Analysis] [Abstract] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/04/2022] [Accepted: 03/23/2022] [Indexed: 01/19/2023] Open
Abstract
BackgroundMicrospherophakia (MSP) is a rare ocular condition, the lens surgery of which is complicated by both insufficient zonules and undersized capsule.MethodsThis study included MSP eyes managed with phacoemulsification combined with supra-capsular and scleral-fixated intraocular lens implantation (SCSF-IOL) and made the comparison with those treated by transscleral-fixated modified capsular tension ring and in-the-bag intraocular lens implantation (MCTR-IOL).ResultsA total of 20 MSP patients underwent SCSF-IOL, and 17 patients received MCTR-IOL. The postoperative best corrected visual acuity was significantly improved in both groups (P < 0.001), but no difference was found between the groups (P = 0.326). The IOL tilt was also comparable (P = 0.216). Prophylactic Nd:YAG laser posterior capsulotomy was performed 1 week to 1 month after the SCSF-IOL procedure. In the SCSF-IOL group, two eyes (10.00%) needed repeated laser treatment and one eye (5.00%) had a decentered capsule opening. Posterior capsule opacification was the most common complication (6, 35.29%) in the MCTR group. No IOL dislocation, secondary glaucoma, or retinal detachment was observed during follow-up.ConclusionsSCSF-IOL is a viable option for managing MSP and is comparable with the MCTR-IOL. Nd:YAG laser posterior capsulotomy was necessary to prevent residual capsule complications after the SCSF-IOL procedure.
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Affiliation(s)
- Ze-Xu Chen
- Eye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, China
- NHC Key Laboratory of Myopia, Fudan University, Shanghai, China
- Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China
- Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China
| | - Zhen-Nan Zhao
- Eye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, China
- NHC Key Laboratory of Myopia, Fudan University, Shanghai, China
- Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China
- Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China
| | - Yang Sun
- Eye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, China
- NHC Key Laboratory of Myopia, Fudan University, Shanghai, China
- Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China
- Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China
| | - Wan-Nan Jia
- Eye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, China
- NHC Key Laboratory of Myopia, Fudan University, Shanghai, China
- Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China
- Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China
| | - Jia-Lei Zheng
- Eye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, China
- NHC Key Laboratory of Myopia, Fudan University, Shanghai, China
- Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China
- Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China
| | - Jia-Hui Chen
- Eye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, China
- NHC Key Laboratory of Myopia, Fudan University, Shanghai, China
- Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China
- Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China
| | - Tian-Hui Chen
- Eye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, China
- NHC Key Laboratory of Myopia, Fudan University, Shanghai, China
- Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China
- Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China
| | - Li-Na Lan
- Eye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, China
- NHC Key Laboratory of Myopia, Fudan University, Shanghai, China
- Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China
- Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China
| | - Yong-Xiang Jiang
- Eye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, China
- NHC Key Laboratory of Myopia, Fudan University, Shanghai, China
- Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China
- Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China
- *Correspondence: Yong-Xiang Jiang
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João MD, Costa JV, Monteiro T, Franqueira N, Faria Correia F, Vaz F. Intraocular Lens Position and Anterior Chamber Parameters Evaluation After Nd:YAG Laser Posterior Capsulotomy for Posterior Capsular Opacification Using Anterior Segment Swept-Source Optical Coherence Tomography. Clin Ophthalmol 2022; 16:153-159. [PMID: 35082482 PMCID: PMC8785224 DOI: 10.2147/opth.s349649] [Citation(s) in RCA: 1] [Impact Index Per Article: 0.3] [Reference Citation Analysis] [Abstract] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/16/2021] [Accepted: 12/17/2021] [Indexed: 11/23/2022] Open
Abstract
Purpose Patients and Methods Results Conclusion
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Affiliation(s)
- Marina Delgado João
- Ophthalmology Department, Hospital de Braga, Braga, Portugal
- Correspondence: Marina Delgado João, Tel +351 253 027 000, Fax +351 253 027 999, Email
| | | | - Tiago Monteiro
- Ophthalmology Department, Hospital de Braga, Braga, Portugal
| | - Nuno Franqueira
- Ophthalmology Department, Hospital de Braga, Braga, Portugal
| | | | - Fernando Vaz
- Ophthalmology Department, Hospital de Braga, Braga, Portugal
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Gu X, Chen X, Yang G, Wang W, Xiao W, Jin G, Wang L, Dai Y, Ruan X, Liu Z, Luo L, Liu Y. Determinants of intraocular lens tilt and decentration after cataract surgery. ANNALS OF TRANSLATIONAL MEDICINE 2020; 8:921. [PMID: 32953721 PMCID: PMC7475414 DOI: 10.21037/atm-20-1008] [Citation(s) in RCA: 30] [Impact Index Per Article: 6.0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Subscribe] [Scholar Register] [Indexed: 12/21/2022]
Abstract
Background To identify the main determinants of intraocular lens (IOL) tilt and decentration after cataract surgery using a novel anterior segment optical coherence tomography (AS-OCT) method. Methods Fifty-six patients who underwent phacoemulsification with IOL implantation in one eye were continuously enrolled in this cohort study. Axial length (AL) was measured with IOL Master 700. The tilt and decentration of patients’ preoperative crystalline lenses and postoperative IOLs, as well as crystalline lens thickness (LT), were measured using AS-OCT before surgery and 1 week after surgery. Results The mean tilt and decentration of the patients’ preoperative crystalline lenses were 4.90°±1.81° and 0.21±0.02 mm, and the mean tilt and decentration of IOLs were 4.75°±1.66° and 0.21±0.02 mm, respectively. There were no significant differences in magnitude, direction of tilt, or decentration between crystalline lenses and IOLs. The strongest determinant of IOL tilt was preoperative crystalline lens tilt (R2=0.512, P<0.001), followed by AL (R2=0.154, P=0.003). Additionally, crystalline lens decentration and AL explained 54.6% of the variability in IOL decentration. AL was the factor most highly associated with IOL decentration (R2=0.332, P<0.001), rather than crystalline lens decentration (R2=0.214, P<0.001). Conclusions The position of the preoperative crystalline lens and AL were the critical determinants of IOL tilt and decentration. The tilt and decentration of IOLs will be greater in patients with larger tilt and decentration of crystalline lenses, or shorter and longer AL.
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Affiliation(s)
- Xiaoxun Gu
- State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China
| | - Xiaoyun Chen
- State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China
| | - Guangyao Yang
- State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China
| | - Wei Wang
- State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China
| | - Wei Xiao
- State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China
| | - Guangming Jin
- State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China
| | - Lanhua Wang
- State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China
| | - Ye Dai
- State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China
| | - Xiaoting Ruan
- State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China
| | - Zhenzhen Liu
- State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China
| | - Lixia Luo
- State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China
| | - Yizhi Liu
- State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China
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Liu Y, Gao Y, Liu R, Hu C, Ma B, Miao J, Luo J, Qi H. Influence of angle kappa-customized implantation of rotationally asymmetric multifocal intraocular lens on visual quality and patient satisfaction. Acta Ophthalmol 2020; 98:e734-e742. [PMID: 31981307 DOI: 10.1111/aos.14356] [Citation(s) in RCA: 13] [Impact Index Per Article: 2.6] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/02/2019] [Accepted: 12/31/2019] [Indexed: 12/19/2022]
Abstract
PURPOSE To evaluate the visual outcomes and patient satisfaction with angle kappa-customized implantation of SBL-3 (Lenstec, Inc.; +3 D), a rotationally asymmetric multifocal intraocular lens (MIOL). METHODS This was a prospective randomized control study. Data from consecutive patients, who underwent bilateral implantation of SBL-3 MIOL from June 2017 to August 2018, were enrolled in the study. One eye of each patient was randomly chosen to receive a horizontal IOL placement (control group), while the other eye received angle kappa-customized placement (design group). The outcomes include uncorrected distance visual acuity (UDVA), uncorrected intermediate visual acuity (UIVA), uncorrected near visual acuity (UNVA), defocus curve, contrast sensitivity, quality of vision and patient satisfaction. The follow-up was 3 months. RESULTS The study enrolled 80 eyes of 40 patients. There was no significant difference in mean UDVA, UIVA and UNVA between the two groups. The design group showed significantly better visual acuity at -1.50 D of defocus, based on the defocus curve (p = 0.022), and less vertical coma (p = 0.002) than the control group. No significant differences in contrast sensitivity, modulation transfer function, Strehl ratio and patient satisfaction were found between the two groups. CONCLUSION Angle kappa-customized implantation of SBL-3 had little impact on visual outcomes and patient satisfaction, except for a moderate impact on intermediate visual acuity.
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Affiliation(s)
- Yiyun Liu
- Department of Ophthalmology Peking University Third Hospital Beijing China
- Beijing Key Laboratory of Restoration of Damaged Ocular Nerve Peking University Third Hospital Beijing China
| | - Yufei Gao
- Department of Ophthalmology Peking University Third Hospital Beijing China
- Beijing Key Laboratory of Restoration of Damaged Ocular Nerve Peking University Third Hospital Beijing China
| | - Rongjun Liu
- Department of Ophthalmology Peking University Third Hospital Beijing China
- Beijing Key Laboratory of Restoration of Damaged Ocular Nerve Peking University Third Hospital Beijing China
| | - Chenxi Hu
- Department of Ophthalmology Peking University Third Hospital Beijing China
- Beijing Key Laboratory of Restoration of Damaged Ocular Nerve Peking University Third Hospital Beijing China
| | - Baikai Ma
- Department of Ophthalmology Peking University Third Hospital Beijing China
- Beijing Key Laboratory of Restoration of Damaged Ocular Nerve Peking University Third Hospital Beijing China
| | - Jinhong Miao
- Department of Ophthalmology Peking University Third Hospital Beijing China
- Beijing Key Laboratory of Restoration of Damaged Ocular Nerve Peking University Third Hospital Beijing China
| | - Jinhua Luo
- Department of Ophthalmology Peking University Third Hospital Beijing China
- Beijing Key Laboratory of Restoration of Damaged Ocular Nerve Peking University Third Hospital Beijing China
- China Academy of Chinese Medical Sciences • Eye Hospital Beijing China
| | - Hong Qi
- Department of Ophthalmology Peking University Third Hospital Beijing China
- Beijing Key Laboratory of Restoration of Damaged Ocular Nerve Peking University Third Hospital Beijing China
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Rementería-Capelo LA, García-Pérez JL, Contreras I, Blázquez V, Ruiz-Alcocer J. Automated refraction after trifocal and trifocal toric intraocular lens implantation. Eur J Ophthalmol 2020; 31:1031-1038. [PMID: 32264702 DOI: 10.1177/1120672120914848] [Citation(s) in RCA: 2] [Impact Index Per Article: 0.4] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 01/19/2023]
Abstract
BACKGROUND To analyze the correlation between automated refraction and manifest refraction after implantation of a trifocal intraocular lens or its toric version. METHODS This cross-sectional study involved 105 eyes of 105 patients. Subjects were divided in two groups: 62 with trifocal (AcrySof PanOptix) and 43 with trifocal toric (AcrySof PanOptix Toric) intraocular lenses. Automated refraction was employed as starting point for obtaining the manifest refraction. Automated refraction and manifest refraction measurements were analyzed and compared using the vector analysis 3 months after the surgery. RESULTS In both groups, the higher differences between automated refraction and manifest refraction measurements were found for the cylinder and the spherical equivalent (M). Cylinder values for PanOptix were: -0.60 ± 0.36 D with automated refraction and -0.17 ± 38 D with manifest refraction (p < 0.001); for PanOptix Toric, the values were: -0.49 ± 0.31 D with automated refraction and -0.05 ± 0.21 D with manifest refraction (p < 0.001). M values for PanOptix were: -0.23 ± 0.31 D with automated refraction and -0.03 ± 0.16 D with manifest refraction (p < 0.001); for PanOptix Toric, the values were: -0.13 ± 0.40 D with automated refraction and 0.01 ± 0.12 D with manifest refraction (p < 0.001). For the PanOptix group, intraclass correlation coefficients were: 0.51 (sphere), 0.64 (cylinder), 0.42 (M), 0.62 (J0), and 0.37 (J45). For the PanOptix Toric group, the intraclass correlation coefficients were: 0.39 (sphere), 0.61 (cylinder), 0.39 (M), 0.53 (J0), and 0.09 (J45). CONCLUSION The results of this study suggest that patients implanted with the trifocal and the trifocal toric intraocular lens under study showed similar automated refraction results between them, with a slight trend to more negative amounts of cylinder and M. Nevertheless, clinicians should carefully confirm all parameters of the refraction with manifest refraction.
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Affiliation(s)
| | | | - Inés Contreras
- Clínica Rementería, Madrid, Spain.,Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigaciones Sanitaria (IRYCIS), Madrid, Spain
| | | | - Javier Ruiz-Alcocer
- Departamento de Optometría y Visión, Facultad de Óptica y Optometría, Universidad Complutense de Madrid, Madrid, Spain
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Antonio‐Santos A, Vedula SS, Hatt SR, Powell C, Cochrane Eyes and Vision Group. Occlusion for stimulus deprivation amblyopia. Cochrane Database Syst Rev 2020; 3:CD005136. [PMID: 32203629 PMCID: PMC7089638 DOI: 10.1002/14651858.cd005136.pub4] [Citation(s) in RCA: 3] [Impact Index Per Article: 0.6] [Reference Citation Analysis] [Abstract] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Indexed: 02/05/2023]
Abstract
BACKGROUND Stimulus deprivation amblyopia (SDA) develops due to an obstruction to the passage of light secondary to a condition such as cataract. The obstruction prevents formation of a clear image on the retina. SDA can be resistant to treatment, leading to poor visual prognosis. SDA probably constitutes less than 3% of all amblyopia cases, although precise estimates of prevalence are unknown. In high-income countries, most people present under the age of one year; in low- to middle-income countries, people are likely to be older at the time of presentation. The mainstay of treatment is correction of the obstruction (e.g., removal of the cataract) and then occlusion of the better-seeing eye, but regimens vary, can be difficult to execute, and traditionally are believed to lead to disappointing results. OBJECTIVES To evaluate the effectiveness of occlusion therapy for SDA in an attempt to establish realistic treatment outcomes and to examine evidence of any dose-response effect and assess the effect of the duration, severity, and causative factor on the size and direction of the treatment effect. SEARCH METHODS We searched CENTRAL (2018, Issue 12), which contains the Cochrane Eyes and Vision Trials Register; Ovid MEDLINE; Embase.com; and five other databases. We used no date or language restrictions in the electronic searches. We last searched the databases on 12 December 2018. SELECTION CRITERIA We planned to include randomized controlled trials (RCTs) and controlled clinical trials of participants with unilateral SDA with visual acuity worse than 0.2 LogMAR or equivalent. We specified no restrictions for inclusion based upon age, gender, ethnicity, comorbidities, medication use, or the number of participants. DATA COLLECTION AND ANALYSIS We used standard Cochrane methodology. MAIN RESULTS We identified no trials that met the inclusion criteria specified in the protocol for this review. AUTHORS' CONCLUSIONS We found no evidence from RCTs or quasi-randomized trials on the effectiveness of any treatment for SDA. RCTs are needed in order to evaluate the safety and effectiveness of occlusion, duration of treatment, level of vision that can be realistically achieved, effects of age at onset and magnitude of visual defect, optimum occlusion regimen, and factors associated with satisfactory and unsatisfactory outcomes with the use of various interventions for SDA.
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Affiliation(s)
- Aileen Antonio‐Santos
- Hauenstein Neurosciences, Mercy Health Saint Mary's245 Cherry Street SESuite 204Grand RapidsMichiganUSA49503
| | - S Swaroop Vedula
- Johns Hopkins University3400 N. Charles StreetBaltimoreMarylandUSA21218
| | - Sarah R Hatt
- Mayo ClinicDepartment of OphthalmologyGuggenheim 9200 1st St. SWRochesterMinnesotaUSA55905
| | - Christine Powell
- Royal Victoria InfirmaryDepartment of OphthalmologyClaremont WingQueen Victoria RoadNewcastle upon TyneUKNE1 4LP
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Influence of Angle κ and Higher-Order Aberrations on Visual Quality Employing Two Diffractive Trifocal IOLs. J Ophthalmol 2019; 2019:7018937. [PMID: 31885892 PMCID: PMC6900936 DOI: 10.1155/2019/7018937] [Citation(s) in RCA: 13] [Impact Index Per Article: 2.2] [Reference Citation Analysis] [Abstract] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 06/20/2019] [Revised: 09/21/2019] [Accepted: 10/25/2019] [Indexed: 01/19/2023] Open
Abstract
Prospective, randomized, comparative, and controlled study to estimate the association between angle κ distance and higher-order aberrations (HOAs) with postoperative visual acuity after presbyopia-correcting IOL implantation. Forty-three eyes from 43 patients were included and randomly assigned in two groups for either AT LISA tri 839MP or Acrysof IQ PanOptix IOL implantation. The OPD-Scan III analyzer was utilized to assess the angle κ distance and higher-order aberration (HOAs). Twenty-three eyes were in the Acrysof IQ PanOptix group and 20 patients in the AT LISA tri 839MP group. The uncorrected distance visual acuity (UDVA) for the PanOptix group was 0.092 ± 0.10, whereas for AT LISA tri was 0.050 ± 0.06 (P=0.229). The uncorrected intermediate visual acuity (UIVA) for the PanOptix group was 0.173 ± 0.18, whereas for AT LISA tri, it was 0.182 ± 0.11 (P=0.669). Uncorrected near visual acuity (UNVA) was 0.068 ± 0.04 and 0.085 ± 0.07, respectively (P=0.221). Also, correlation coefficient between HOAs and the Strehl ratio for each group were −0.768 (P < 0.0001) and −0.863 (P=0.0001). Patients implanted with both trifocal IOLs showed excellent postoperative visual performance at all distances at the six-month follow-up visit. No association was found between angle κ distance and postoperative visual acuity regardless of the angle κ magnitude or the two trifocal IOLs inner optical diameter. Also, internal aberrations demonstrated a significant inverse correlation with the Strehl ratio for both trifocal IOLs.
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Xu J, Zheng T, Lu Y. Effect of Decentration on the Optical Quality of Monofocal, Extended Depth of Focus, and Bifocal Intraocular Lenses. J Refract Surg 2019; 35:484-492. [DOI: 10.3928/1081597x-20190708-02] [Citation(s) in RCA: 19] [Impact Index Per Article: 3.2] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/26/2019] [Accepted: 07/08/2019] [Indexed: 12/18/2022]
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