• cataract surgery
• glare
• lens material
• multifocal intraocular lens
• spectacle independence

• CICARE
• Cataract ultrasound emulsification
• Communication intervention
• Sequential nursing
• Vision restoration

• Humans
• Female
• Male
• Waiting Lists
• Feasibility Studies
• Aged
• Cross-Sectional Studies
• Middle Aged
• Cataract Extraction
• Cataract/physiopathology
• Cataract/diagnosis
• Contrast Sensitivity/physiology
• Postal Service
• Aged, 80 and over
• Visual Acuity/physiology
• Adult

• Cataract
• Cataract surgery
• Cognitive decline
• Cognitive impairment
• Dementia

• Humans
• Cataract Extraction
• Cognitive Dysfunction
• Aged
• Cataract/complications
• Cognition/physiology
• Dementia
• Risk Factors

• anxiety
• cataract surgery
• depression
• older adults

• Humans
• Anxiety/etiology
• Anxiety/epidemiology
• Cataract/psychology
• Cataract/complications
• Cataract Extraction
• Depression/etiology
• Mental Health

• cataract surgery
• dementia
• mild cognitive impairment
• mini-mental state examination
• older people

• 21K09707 Health Labour Sciences Research under Grant
• 22K21154 Health Labour Sciences Research under Grant

• age-related macular degeneration
• keratoconus
• refractive error
• senile cataract
• vision-related quality of life

• Cataract
• China
• Humans
• Keratoconus
• Macular Degeneration
• National Eye Institute (U.S.)
• Pilot Projects
• Quality of Life
• Refractive Errors
• Surveys and Questionnaires
• United States
• Visual Acuity

• age-related macular degeneration
• cataracts
• diabetic retinopathy
• elderly
• glaucoma
• health-enhancement program
• policymaker
• refractive error
• visual impairment

• cataract surgery
• health decision making
• spectacles
• target refraction

To determine the changes in vision-related quality of life and psychological distress after cataract surgery in monocular patients and to compared these with a control group of age- and gender-matched binocular patients.

We enrolled 40 monocular patients and 40 binocular patients who underwent cataract surgery from August 2017 to December 2018. All participants undertook eye examinations and answered questionnaires (the National Eye Institute Visual Function Questionnaire, Self-rating Anxiety Scale, and Self-rating Depression Scale) before and after cataract surgery.

The monocular patients had significantly worse mean CDVA than the binocular patients before and after surgery. However, there was no significant difference between the increases gained by the two groups. Mean composite VFQ-25 scores of the monocular group were significantly lower than those of the binocular group before and after surgery, but the improvement experienced by the monocular group was statistically larger than the binocular group (37.20 ± 12.84 vs. 19.11 ± 5.13, P < 0.001). Mean standard SAS scores of monocular patients were significantly higher than those of binocular controls before and after surgery, while monocular patients experienced a significant greater decline of SAS scores (−9.41 ± 5.39 VS −3.84 ± 1.61, P < 0.001). Mean standard SDS scores of the monocular group were significantly higher than those of the control group before and after surgery, but the monocular group experienced a significantly greater decline of SDS scores following cataract surgery (−11.91 ± 6.38 VS −4.78 ± 1.79, P < 0.001). There was a significant correlation between the preoperative logMAR CDVA and both the postoperative logMAR CDVA (r = 0.63, P < 0.001) and the changes in the logMAR CDVA (r = −0.881, P < 0.001) for monocular patients. Linear regression analyses suggested that higher postoperative VFQ-25 scores had significant associations with better preoperative CDVA and the absence of systemic comorbidity (both P < 0.05). Age and ocular comorbidity were significantly associated with postoperative SAS scores (both P < 0.05). Age and systemic comorbidity remained significant impact factors for SDS scores (both P < 0.05).

Monocular patients reported greater improvement in vision-related quality of life and greater decline in the level of anxiety and depression than binocular control subjects, despite having similar CDVA gains after cataract surgery. We argue that it is not a better choice for monocular patients to delay cataract surgery until the cataract is very advanced. A clear understanding of the impact of cataract surgery on vision-related quality of life and psychological distress in monocular patients is needed by ophthalmologists when making surgery decision.

• Accommodation, Ocular/physiology
• Aged
• Aged, 80 and over
• China/epidemiology
• Eye Diseases/complications
• Eye Diseases/epidemiology
• Eye Diseases/physiopathology
• Female
• Follow-Up Studies
• Humans
• Incidence
• Male
• Memory/physiology
• Memory Disorders/epidemiology
• Memory Disorders/etiology
• Memory Disorders/psychology
• Middle Aged
• Prognosis
• Time Factors
• United States/epidemiology
• Vision Disorders/complications
• Vision Disorders/epidemiology
• Vision Disorders/physiopathology
• Visual Acuity/physiology

• R21 AG031372 NIA NIH HHS
• R01 AG037031 NIA NIH HHS
• U01 AG009740 NIA NIH HHS

• NEI VFQ-25
• Rasch analysis
• VF-14
• cataract
• psychometric properties
• vision-related quality of life

• chopping in cataract
• simulator
• wet-lab

To compare spectacle independence, patient-reported outcomes (PROs), and dysphotopsia after multifocal intraocular lens (IOL) implantation with the AcrySof PanOptix trifocal or the ReSTOR +2.5/3.0 D or ReSTOR +2.5 D mini-monovision multifocal IOL.

Prospective, open-label, multicenter analysis of PROs, spectacle independence, and satisfaction among patients undergoing cataract surgery who had been implanted at least 1 month previously with AcrySof IQ PanOptix or PanOptix Toric trifocal (n = 59) IOLs bilaterally. Results were compared to outcomes from a similar study with the AcrySof ReSTOR 2.5/3.0 or the ReSTOR ActiveFocus 2.5 mini-monovision lens [n = 191]).

Spectacle independence was significantly higher in the PanOptix cohort, with 83% of patients “never” needing glasses for any activity versus 36% in the ReSTOR 2.5 mini-monovision and 34% in the ReSTOR 2.5/3.0 cohorts. No significant differences in patient satisfaction rates were reported between the three cohorts. Glare and halo were rated “extremely” noticeable more with the PanOptix (10%) than with the ReSTOR 2.5 mini-monovision (1%) or ReSTOR 2.5/3.0 (3%). BCVA differences were not statistically significant, and no new safety concerns were reported.

The AcrySof PanOptix trifocal provides significantly greater spectacle independence across all measured activities than the AcrySof ReSTOR multifocal IOLs.

• cataract surgery
• glare
• multifocal intraocular lens
• spectacle independence

Reduced visual function is associated with diminished quality of life as well as decreased physical and mental health. Poor visual function related to cataracts is also a risk factor for falls and traffic accidents, which may lead to hospital admissions and limit independence.

To evaluate patients' satisfaction, visual functions and spectacle independence among patients in the Central Region of Ghana who had cataract surgery in one eye.

A hospital-based prospective cohort study was carried out on 146 patients booked for cataract surgery: 16 were lost through follow-ups whilst 130 completed the study. Visual functions including visual acuity, contrast sensitivity, stereopsis and colour vision were assessed before and after a month of cataract surgery. Objective and subjective refractions were performed to determine the post-surgery refractive status of the participants. Participants completed the NEI-VFQ 25 questionnaire and the scores obtained were used as a construct of their satisfaction.

The NEI-VFQ 25 questionnaire scores indicated patients' satisfaction was high with an average quality of life score of 77.46. Patients satisfaction was strongly correlated with contrast sensitivity (r=0.653, p<0.001) but moderately correlated with visual acuity (r=-0.554, p<0.001), stereopsis (r=0.490, p<0.001) and colour vision (r=0.466, p<0.001). Contrast sensitivity was a better predictor of patients' satisfaction than visual acuity and stereopsis. Spectacle independence at distance was achieved in only 44.6% of the participants and 5.4% at near. There was a significant (p>0.001) association between spectacle independence and the two types of cataract surgery performed which included Small Incision Cataract Surgery (SICS) and Extracapsular Cataract Extraction (ECCE). Among those who were spectacle independent, 53.4% of them were low vision patients.

Satisfaction of patients after cataract surgery was high but was greatly influenced by visual functions with contrast sensitivity being a better predictor of satisfaction than visual acuity and stereopsis. Spectacle independence after cataract surgery was low at distance and extremely low at near. The type of cataract surgery performed influenced thespectacle independence.

• TNO
• cataract surgery
• contrast sensitivity
• intraocular lens
• spectacle independence

• Adolescent
• Adult
• Aged
• Cataract/psychology
• Cataract Extraction
• Eyeglasses/statistics & numerical data
• Female
• Ghana
• Humans
• Lens Implantation, Intraocular/adverse effects
• Lenses, Intraocular
• Male
• Middle Aged
• Patient Satisfaction
• Prospective Studies
• Quality of Life/psychology
• Vision Tests
• Visual Acuity
• Young Adult

• low luminance visual acuity
• low luminance deficit
• visual acuity
• choroideremia
• retinitis pigmentosa

• Choroideremia/genetics
• Eye Proteins
• Germany
• Humans
• Italy
• Male
• Retinitis Pigmentosa/diagnosis
• Visual Acuity
• Visual Fields

• ICA-CDRF-2016-02-002 Department of Health

• microbial keratitis
• patient reported outcomes
• corneal transplant

• Adolescent
• Adult
• Aged
• Aged, 80 and over
• Corneal Transplantation
• Electronic Health Records
• Eye Infections, Bacterial/microbiology
• Eye Infections, Bacterial/psychology
• Eye Infections, Bacterial/surgery
• Female
• Humans
• Keratitis/microbiology
• Keratitis/psychology
• Keratitis/surgery
• Male
• Middle Aged
• Patient Reported Outcome Measures
• Quality of Life/psychology
• Sickness Impact Profile
• Surveys and Questionnaires
• Visual Acuity/physiology

• R01 EY031033 NEI NIH HHS

Epiphora causes deterioration in contrast sensitivity in some eye diseases. This study was conducted to investigate contrast sensitivity in eyes with epiphora caused by lacrimal passage obstruction.

This single-center, prospective case series enrolled 57 patients with unilateral lacrimal passage obstruction. The best-corrected visual acuity (BCVA), contrast sensitivity function, and lower tear meniscus of the affected and contralateral unaffected eyes were compared. The area under the log contrast sensitivity function (AULCSF) was calculated.

The BCVA did not significantly differ between the affected and contralateral eyes, while the AULCSF was significantly lower in the affected eyes than that in the contralateral eyes (median 1.35, interquartile range 1.22–1.44 vs. median 1.36, interquartile range 1.28–1.46, P = 0.032). Lower tear meniscus parameters were significantly higher in the affected eyes than those in the contralateral eyes (P < 0.005).

The contrast sensitivity function is significantly diminished in eyes with epiphora caused by lacrimal passage obstruction.

• Aged
• Case-Control Studies
• Contrast Sensitivity/physiology
• Female
• Humans
• Lacrimal Apparatus/physiology
• Lacrimal Apparatus Diseases/metabolism
• Lacrimal Apparatus Diseases/physiopathology
• Lacrimal Duct Obstruction/physiopathology
• Male
• Middle Aged
• Prospective Studies
• Tears
• Visual Acuity/drug effects
• Visual Acuity/physiology

To evaluate the relationship between cataract types and subjective visual function among patients with age-related cataract.

This was a prospective, multicenter, 831 Chinese patient-based, cross-sectional study. Patients were administered the Visual Function Index-14 (VF-14) and the 25-item National Eye Institute Visual Functioning Questionnaire (NEI-VFQ-25) to evaluate their subjective visual function. Lens Opacities Classification System III (LOCS III) was used to evaluate the type of cataract. Relationships among these parameters were analyzed.

LOCS III cortical (C) and posterior subcapsular scores are negatively associated with VF-14 (r = − 0.188, P < 0.01; r = − 0.146, P < 0.01) and total score of NEI-VFQ-25 (r = − 0.223, P < 0.01; r = − 0.160, P < 0.01), respectively; LOCS III nuclear opalescence (NO) score is positively associated with VF-14 (r = 0.087, P < 0.05) and total score of NEI-VFQ-25 (r = 0.097, P < 0.05). In multiple linear regression, a decrease in the LOCS III C score is a significant predictor for improvement of the total score of NEI-VFQ-25 (β = − 1.286, P < 0.05). In contrast, an increase in LOCS III NO score is a significant predictor for improvement of VF-14 (β = 3.826, P < 0.01) and total score of NEI-VFQ-25 (β = 4.618, P < 0.01). Patients with LOCS III C score ≤ 2 have higher VF-14 (49.38 versus 43.74, P < 0.01), total (80.73 versus 71.58, P < 0.01) and subscale scores of NEI-VFQ-25 than patients with LOCS III C score > 2.

Cortical cataract has adverse effects on subjective visual function, while mild-to-moderate nuclear cataract has positive effects. Furthermore, “LOCS III C score > 2” can be a potential cutoff as a reference for cataract surgery without self-assessing questionnaires.

The online version of this article (10.1007/s10792-020-01353-0) contains supplementary material, which is available to authorized users.

• Age-related cataract
• Cataract types
• NEI-VFQ-25
• Subjective visual function
• VF-14

• Cataract Surgery
• Multifocal Intraocular Lens
• Presbyopia
• Pseudophakic Intraocular Lens
• Refractive Surgery