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For: Patel S, Srivastava S, Singh MR, Singh D. Mechanistic insight into diabetic wounds: Pathogenesis, molecular targets and treatment strategies to pace wound healing. Biomed Pharmacother 2019;112:108615. [PMID: 30784919 DOI: 10.1016/j.biopha.2019.108615] [Citation(s) in RCA: 551] [Impact Index Per Article: 91.8] [Reference Citation Analysis] [What about the content of this article? (0)] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/17/2018] [Revised: 01/19/2019] [Accepted: 01/23/2019] [Indexed: 12/15/2022]  Open
Number Cited by Other Article(s)
1
Zhao RN, Ke YY, Sun HY, Quan C, Xu Q, Li J, Guan JQ, Zhang YM. Achievements and challenges in glucose oxidase-instructed multimodal synergistic antibacterial applications. Microbiol Res 2025;297:128149. [PMID: 40187057 DOI: 10.1016/j.micres.2025.128149] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/22/2024] [Revised: 02/26/2025] [Accepted: 03/17/2025] [Indexed: 04/07/2025]
2
Yu Z, Wang J, Li T, Gao L. Melatonin promotes diabetic wound healing by mediating mitochondrial function in endothelial cells through the AMPK/SIRT1/HIF-1α pathway. Tissue Cell 2025;95:102884. [PMID: 40233668 DOI: 10.1016/j.tice.2025.102884] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/19/2024] [Revised: 03/20/2025] [Accepted: 03/20/2025] [Indexed: 04/17/2025]
3
Duan L, Liu G, Liao F, Xie C, Shi J, Yang X, Zheng F, Reis RL, Kundu SC, Xiao B. Antheraea pernyi silk nanofibrils with inherent RGD motifs accelerate diabetic wound healing: A novel drug-free strategy to promote hemostasis, regulate immunity and improve re-epithelization. Biomaterials 2025;318:123127. [PMID: 39879843 DOI: 10.1016/j.biomaterials.2025.123127] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/26/2024] [Revised: 01/16/2025] [Accepted: 01/23/2025] [Indexed: 01/31/2025]
4
Liao Y, Zhang Z, Hu W, Zhang S, Zhao Y, Ouyang L, Yu C, Liu M, Mi B, Liu G. Glucose-regulating hydrogel for immune modulation and angiogenesis through metabolic reprogramming and LARP7-SIRT1 pathway in infected diabetic wounds. Biomaterials 2025;318:123182. [PMID: 39951832 DOI: 10.1016/j.biomaterials.2025.123182] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/31/2024] [Revised: 02/01/2025] [Accepted: 02/08/2025] [Indexed: 02/16/2025]
5
Ganjibakhsh M, Tkachenko Y, Knutsen RH, Kozel BA. Toward a rational therapeutic for elastin related disease: Key considerations for elastin based regenerative medicine strategies. Matrix Biol 2025;138:8-21. [PMID: 40158781 DOI: 10.1016/j.matbio.2025.03.003] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/04/2025] [Revised: 03/07/2025] [Accepted: 03/23/2025] [Indexed: 04/02/2025]
6
Zoheir KMA, Ali NI, Ashour AE, Kishta MS, Othman SI, Rudayni HA, Rashad AA, Allam AA. Lipoic acid improves wound healing through its immunomodulatory and anti-inflammatory effects in a diabetic mouse model. J Diabetes Metab Disord 2025;24:56. [PMID: 39868353 PMCID: PMC11759746 DOI: 10.1007/s40200-025-01559-y] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 05/03/2024] [Accepted: 10/28/2024] [Indexed: 01/28/2025]
7
Zhou X, Chen S, Savitz B, Yu N, Perdikis G, Duckworth K, Dean Y, Long X, Lineaweaver W. Comparative efficacy of different functional hydrogel dressings in healing diabetic foot ulcer: A systematic review and network meta-analysis. Diabetes Obes Metab 2025;27:3431-3441. [PMID: 40197692 DOI: 10.1111/dom.16367] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 01/22/2025] [Revised: 03/05/2025] [Accepted: 03/13/2025] [Indexed: 04/10/2025]
8
Liu X, Wang W, Wang Y, Duan W, Liu C, Quan P, Xiao J, Zhang Y, Hao Y, Fang L, Song Y, Zhang W. Biochemical strategy-based hybrid hydrogel dressing-mediated in situ synthesis of selenoproteins for DFU immunity-microbiota homeostasis regulation. Biomaterials 2025;317:123114. [PMID: 39854881 DOI: 10.1016/j.biomaterials.2025.123114] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 06/21/2024] [Revised: 01/14/2025] [Accepted: 01/16/2025] [Indexed: 01/27/2025]
9
Tosaka R, Eguchi T, Ishizuka T, Kawaguchi K, Nagashima T, Nakayama R, Hamada Y. The effects of silk sheets derived from germ-free silkworms on wound healing of full-thickness epithelial defects. Burns 2025;51:107470. [PMID: 40327970 DOI: 10.1016/j.burns.2025.107470] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/25/2024] [Revised: 02/24/2025] [Accepted: 03/24/2025] [Indexed: 05/08/2025]
10
Mishra R, Singh TG, Bhatia R, Awasthi A. Unveiling the therapeutic journey of snail mucus in diabetic wound care. NAUNYN-SCHMIEDEBERG'S ARCHIVES OF PHARMACOLOGY 2025;398:6531-6560. [PMID: 39869187 DOI: 10.1007/s00210-024-03657-9] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Subscribe] [Scholar Register] [Received: 10/01/2024] [Accepted: 11/19/2024] [Indexed: 01/28/2025]
11
Summer M, Ali S, Muhammad G, Riaz A. Evaluating the Wound Healing Potential of Characterized Bergenia ciliata-Loaded Salvia hispanica Hydrogel in Diabetic Mice. Microsc Res Tech 2025;88:1917-1934. [PMID: 40014652 DOI: 10.1002/jemt.24826] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/30/2024] [Revised: 01/13/2025] [Accepted: 02/09/2025] [Indexed: 03/01/2025]
12
Mantry S, Das PK, Sankaraiah J, Panda S, Silakabattini K, Reddy Devireddy AK, Barik CS, Khalid M. Advancement on heparin-based hydrogel/scaffolds in biomedical and tissue engineering applications: Delivery carrier and pre-clinical implications. Int J Pharm 2025:125733. [PMID: 40398669 DOI: 10.1016/j.ijpharm.2025.125733] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/06/2025] [Revised: 05/12/2025] [Accepted: 05/14/2025] [Indexed: 05/23/2025]
13
Sharma S, Kishen A. Dysfunctional crosstalk between macrophages and fibroblasts under LPS-infected and hyperglycemic environment in diabetic wounds. Sci Rep 2025;15:17233. [PMID: 40383800 PMCID: PMC12086240 DOI: 10.1038/s41598-025-00673-4] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/21/2024] [Accepted: 04/29/2025] [Indexed: 05/20/2025]  Open
14
Sun X, Li Y, Wang H, Meng Y, Dai X, Du L, Li L. Construction of pH-Sensitive Multifunctional Hydrogel with Synergistic Anti-Inflammatory Effect for Treatment of Diabetic Wounds. Pharmaceutics 2025;17:644. [PMID: 40430935 PMCID: PMC12114684 DOI: 10.3390/pharmaceutics17050644] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Download PDF] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/25/2025] [Revised: 05/05/2025] [Accepted: 05/09/2025] [Indexed: 05/29/2025]  Open
15
Pereira AR, Pires PC, Hameed H, Lopes D, Lopes J, Sousa-Oliveira I, Babaie S, Mazzola P, Veiga F, Paiva-Santos AC. Injectable nanocomposite hydrogels for targeted intervention in cancer, wound healing, and bone and myocardial tissue engineering. Drug Deliv Transl Res 2025:10.1007/s13346-025-01864-2. [PMID: 40358831 DOI: 10.1007/s13346-025-01864-2] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Accepted: 04/12/2025] [Indexed: 05/15/2025]
16
Zhang Y, Lin S, Xu X, Yao Y, Feng S, Jiang S, Wang Y, He W, Mo R. Programmable hierarchical hydrogel dressing for sequential release of growth factor and DNase to accelerate diabetic wound healing. J Control Release 2025;383:113825. [PMID: 40339657 DOI: 10.1016/j.jconrel.2025.113825] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/04/2024] [Revised: 04/30/2025] [Accepted: 05/05/2025] [Indexed: 05/10/2025]
17
Zhan Y, Sun H, Zhang Z, Chen X, Xu Z, He Y, Tao S, Fan L, Tan J. Chitosan and polyvinyl alcohol-based bilayer electrospun nanofibrous membrane incorporated with astaxanthin promotes diabetic wound healing by addressing multiple factors. Int J Biol Macromol 2025;311:143921. [PMID: 40324499 DOI: 10.1016/j.ijbiomac.2025.143921] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/09/2024] [Revised: 04/27/2025] [Accepted: 05/02/2025] [Indexed: 05/07/2025]
18
Jha B, Majie A, Roy K, Gorain B. Functional and molecular insights in topical wound healing by ascorbic acid. NAUNYN-SCHMIEDEBERG'S ARCHIVES OF PHARMACOLOGY 2025:10.1007/s00210-025-04180-1. [PMID: 40317316 DOI: 10.1007/s00210-025-04180-1] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Subscribe] [Scholar Register] [Received: 02/06/2025] [Accepted: 04/11/2025] [Indexed: 05/07/2025]
19
Ku YC, Lee YC, Hong YK, Lo YL, Kuo CH, Wang KC, Hsu CK, Yu CH, Lin SW, Wu HL. Deciphering the Dysregulating IGF-1-SP1-CD248 Pathway in Fibroblast Functionality during Diabetic Wound Healing. J Invest Dermatol 2025;145:1180-1195. [PMID: 39293711 DOI: 10.1016/j.jid.2024.07.035] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/26/2024] [Revised: 07/08/2024] [Accepted: 07/31/2024] [Indexed: 09/20/2024]
20
Li Y, Hao Y, Yang X, Zhao J, Chang R, Wang B, Zhan X. Structure characterization of a Bletilla striata homogeneous polysaccharide and its effects on reducing oxidative stress and promoting wound healing in diabetic rats. Int J Biol Macromol 2025;307:141904. [PMID: 40064269 DOI: 10.1016/j.ijbiomac.2025.141904] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/10/2024] [Revised: 02/11/2025] [Accepted: 03/07/2025] [Indexed: 03/20/2025]
21
Zhang Y, Zheng Z, Zhu S, Xu L, Zhang Q, Gao J, Ye M, Shen S, Xing J, Wu M, Xu RX. Electroactive Electrospun Nanofibrous Scaffolds: Innovative Approaches for Improved Skin Wound Healing. ADVANCED SCIENCE (WEINHEIM, BADEN-WURTTEMBERG, GERMANY) 2025;12:e2416267. [PMID: 40190057 PMCID: PMC12079356 DOI: 10.1002/advs.202416267] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Figures] [Subscribe] [Scholar Register] [Received: 12/05/2024] [Revised: 03/05/2025] [Indexed: 05/16/2025]
22
Pan Y, Xia M, Luo J, Lu S. Resveratrol Promotes Wound Healing by Enhancing Angiogenesis via Inhibition of Ferroptosis. Food Sci Nutr 2025;13:e70254. [PMID: 40330211 PMCID: PMC12053223 DOI: 10.1002/fsn3.70254] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/18/2024] [Revised: 04/04/2025] [Accepted: 04/24/2025] [Indexed: 05/08/2025]  Open
23
Chen L, Li Y, Zhang N, Chen T, Li F, Han J, Wang Z, Kannan PR, Sun Z, Fu F, Cheng L, Lu J, Kong X. Injectable dual-cross-linked microalgae-silk gel ameliorates diabetic wound healing by promoting oxygenation and ROS clearance and lessening inflammation. Int J Biol Macromol 2025;309:142897. [PMID: 40203918 DOI: 10.1016/j.ijbiomac.2025.142897] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/13/2025] [Revised: 04/01/2025] [Accepted: 04/05/2025] [Indexed: 04/11/2025]
24
Sharma V, Singh J, Kumar Y, Kumar A, Venkatesan K, Mukherjee M, Sharma AK. Integrated insights into gene expression dynamics and transcription factor roles in diabetic and diabetic-infectious wound healing using rat model. Life Sci 2025;368:123508. [PMID: 40015667 DOI: 10.1016/j.lfs.2025.123508] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/20/2024] [Revised: 02/08/2025] [Accepted: 02/22/2025] [Indexed: 03/01/2025]
25
Tartau CG, Boboc IKS, Mititelu-Tartau L, Bogdan M, Buca BR, Pavel LL, Amalinei C. Exploring the Protective Effects of Traditional Antidiabetic Medications and Novel Antihyperglycemic Agents in Diabetic Rodent Models. Pharmaceuticals (Basel) 2025;18:670. [PMID: 40430489 PMCID: PMC12114790 DOI: 10.3390/ph18050670] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/10/2025] [Revised: 04/28/2025] [Accepted: 04/30/2025] [Indexed: 05/29/2025]  Open
26
Chetty R, Bhagwan R, Govender N. The biopsychosocial effects of transtibial amputation: A South African perspective. Afr J Disabil 2025;14:1404. [PMID: 40357351 PMCID: PMC12067012 DOI: 10.4102/ajod.v14i0.1404] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/31/2024] [Accepted: 12/15/2024] [Indexed: 05/15/2025]  Open
27
Taghdi MH, Al-Masawa ME, Muttiah B, Fauzi MB, Law JX, Zainuddin AA, Lokanathan Y. Three-Dimensional Bioprinted Gelatin-Genipin Hydrogels Enriched with hUCMSC-Derived Small Extracellular Vesicles for Regenerative Wound Dressings. Polymers (Basel) 2025;17:1163. [PMID: 40362948 PMCID: PMC12073717 DOI: 10.3390/polym17091163] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/25/2025] [Revised: 04/17/2025] [Accepted: 04/21/2025] [Indexed: 05/15/2025]  Open
28
Rybka M, Mazurek Ł, Jurak J, Laskowska A, Zajdel M, Czuwara J, Sulejczak D, Szudzik M, Samborowska E, Schwartz RA, Dziadek M, Salagierski S, Drapała A, Ufnal M, Konop M. Keratin-TMAO dressing accelerates full-thickness skin wound healing in diabetic rats via M2-macrophage polarization and the activation of PI3K/AKT/mTOR signaling pathway. Int J Biol Macromol 2025;310:143313. [PMID: 40274140 DOI: 10.1016/j.ijbiomac.2025.143313] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/05/2025] [Revised: 04/14/2025] [Accepted: 04/16/2025] [Indexed: 04/26/2025]
29
Zhou Y, Dai F, Zhao S, Li Z, Liang H, Wang X, Zhao L, Tan H. pH and Glucose Dual-Responsive Hydrogels Promoted Diabetic Wound Healing by Remodeling the Wound Microenvironment. Adv Healthc Mater 2025:e2500810. [PMID: 40237168 DOI: 10.1002/adhm.202500810] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/13/2025] [Revised: 04/02/2025] [Indexed: 04/18/2025]
30
Kananivand M, Nouri F, Yousefi MH, Pajouhi A, Ghorbani H, Afkhami H, Razavi ZS. Mesenchymal stem cells and their exosomes: a novel approach to skin regeneration via signaling pathways activation. J Mol Histol 2025;56:132. [PMID: 40208456 DOI: 10.1007/s10735-025-10394-7] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/01/2024] [Accepted: 03/06/2025] [Indexed: 04/11/2025]
31
Sanpinit S, Issuriya A, Sakulkeo O, Wetchakul P, Limsuwan S, Na-Phatthalung P, Kantisin S, Tang J, Chusri S. Mechanisms underlying the wound healing and tissue regeneration properties of a novel gauze dressing impregnated with traditional herbal medicine (Ya-Samarn-Phlae) in type 2 diabetic Goto-Kakizaki (GK) rats. Front Pharmacol 2025;16:1574715. [PMID: 40271074 PMCID: PMC12015241 DOI: 10.3389/fphar.2025.1574715] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/11/2025] [Accepted: 04/01/2025] [Indexed: 04/25/2025]  Open
32
Xuan Q, Cai J, Gao Y, Qiao X, Jin T, Peydayesh M, Zhou J, Sun Q, Zhan L, Liu B, Wang P, Li H, Chen C, Mezzenga R. Amyloid-Templated Ceria Nanozyme Reinforced Microneedle for Diabetic Wound Treatments. ADVANCED MATERIALS (DEERFIELD BEACH, FLA.) 2025;37:e2417774. [PMID: 39995378 PMCID: PMC12004906 DOI: 10.1002/adma.202417774] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Subscribe] [Scholar Register] [Received: 11/16/2024] [Revised: 02/15/2025] [Indexed: 02/26/2025]
33
Erukainure OL, Houreld NN. Vanillin Enhances Photobiomodulation Wound Healing by Modulating Glyco-Oxidative Stress and Glucose Dysmetabolism in Diabetic Wounded Fibroblast Cells. J Cell Mol Med 2025;29:e70537. [PMID: 40194982 PMCID: PMC11975505 DOI: 10.1111/jcmm.70537] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/15/2024] [Revised: 03/20/2025] [Accepted: 03/24/2025] [Indexed: 04/09/2025]  Open
34
Li X, Yi M, Song Z, Ni T, Tu L, Yu M, Zhang L, Shi J, Gao W, Zhang Q, Yan W. A calcitonin gene-related peptide co-crosslinked hydrogel promotes diabetic wound healing by regulating M2 macrophage polarization and angiogenesis. Acta Biomater 2025;196:109-122. [PMID: 40020959 DOI: 10.1016/j.actbio.2025.02.046] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/18/2024] [Revised: 02/07/2025] [Accepted: 02/21/2025] [Indexed: 03/03/2025]
35
Ye P, Yang Y, Liu M, Meng J, Zhao J, Zhao J, Wang J, Lu Q, Liu J, Wang L, Lei J, Wang C. Co-Delivery of Morphologically Switchable Au Nanowire and Hemoglobin-Resveratrol Nanoparticles in the Microneedle for Diabetic Wound Healing Therapy. ADVANCED MATERIALS (DEERFIELD BEACH, FLA.) 2025;37:e2419430. [PMID: 40066484 DOI: 10.1002/adma.202419430] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Subscribe] [Scholar Register] [Received: 12/11/2024] [Revised: 02/25/2025] [Indexed: 04/24/2025]
36
Yin Y, Guo W, Chen Q, Tang Z, Liu Z, Lin R, Pan T, Zhan J, Ren L. A Single H2S-Releasing Nanozyme for Comprehensive Diabetic Wound Healing through Multistep Intervention. ACS APPLIED MATERIALS & INTERFACES 2025;17:18134-18149. [PMID: 40088144 DOI: 10.1021/acsami.5c00889] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Subscribe] [Scholar Register] [Indexed: 03/17/2025]
37
Zhang S, Shao Y, Jin R, Ma B. Combining Network Pharmacology, Molecular Docking, Molecular Dynamics Simulation, and Experimental Validation to Uncover the Efficacy and Mechanisms of Si-Miao-Yong-An Decoction in Diabetic Wound Healing. J Inflamm Res 2025;18:4087-4101. [PMID: 40129870 PMCID: PMC11930845 DOI: 10.2147/jir.s506739] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/29/2024] [Accepted: 02/21/2025] [Indexed: 03/26/2025]  Open
38
Li H, Yu L, Li Z, Li S, Liu Y, Qu G, Chen K, Huang L, Li Z, Ren J, Wu X, Huang J. A Narrative Review of Bioactive Hydrogel Microspheres: Ingredients, Modifications, Fabrications, Biological Functions, and Applications. SMALL (WEINHEIM AN DER BERGSTRASSE, GERMANY) 2025:e2500426. [PMID: 40103506 DOI: 10.1002/smll.202500426] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Subscribe] [Scholar Register] [Received: 01/11/2025] [Revised: 03/02/2025] [Indexed: 03/20/2025]
39
Li Y, Yu S, Zeng J, Zhou S, Cui X, Zhou J, Zhang P. Corilagin enhances wound healing by modulating the macrophage phenotype in diabetic mice. FASEB J 2025;39:e70439. [PMID: 40052815 DOI: 10.1096/fj.202403085rr] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/03/2024] [Revised: 02/18/2025] [Accepted: 02/24/2025] [Indexed: 05/13/2025]
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Wang H, Wei B, WuLan H, Qu B, Li H, Ren J, Han Y, Guo L. Conditioned medium of engineering macrophages combined with soluble microneedles promote diabetic wound healing. PLoS One 2025;20:e0316398. [PMID: 40072964 PMCID: PMC11902060 DOI: 10.1371/journal.pone.0316398] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/29/2024] [Accepted: 12/10/2024] [Indexed: 03/14/2025]  Open
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Tian M, Wu J, Du Q, Han J, Yang M, Li X, Li M, Ding X, Song Y. Revealing the Mechanisms of Shikonin Against Diabetic Wounds: A Combined Network Pharmacology and In Vitro Investigation. J Diabetes Res 2025;2025:4656485. [PMID: 40225010 PMCID: PMC11986939 DOI: 10.1155/jdr/4656485] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Figures] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 05/03/2024] [Accepted: 01/29/2025] [Indexed: 04/15/2025]  Open
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Jing Y, Liu X, Zhu Y, Wu L, Nong W. Metal-organic framework microneedles for precision transdermal drug delivery: design strategy and therapeutic potential. NANOSCALE 2025;17:5571-5604. [PMID: 39918280 DOI: 10.1039/d4nr03898c] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Subscribe] [Scholar Register] [Indexed: 03/08/2025]
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Kaleva MD, Kermedchiev M, Velkova L, Zaharieva MM, Dolashki A, Todorova M, Guncheva M, Dolashka P, Najdenski HM. Synergistic Antibacterial Effect of Mucus Fraction from Cornu aspersum and Cirpofloxacin Against Pathogenic Bacteria Isolated from Wounds of Diabetic Patients. Antibiotics (Basel) 2025;14:260. [PMID: 40149071 PMCID: PMC11939354 DOI: 10.3390/antibiotics14030260] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/28/2024] [Revised: 02/13/2025] [Accepted: 02/21/2025] [Indexed: 03/29/2025]  Open
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Xiao Y, Xu K, Zhao P, Ji L, Hua C, Jia X, Wu X, Diao L, Zhong W, Lyu G, Xing M. Microgels sense wounds' temperature, pH and glucose. Biomaterials 2025;314:122813. [PMID: 39270627 DOI: 10.1016/j.biomaterials.2024.122813] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 06/07/2024] [Revised: 08/23/2024] [Accepted: 09/02/2024] [Indexed: 09/15/2024]
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Tibatan MA, Katana D, Yin CM. The emerging role of nanoscaffolds in chronic diabetic wound healing: a new horizon for advanced therapeutics. JOURNAL OF BIOMATERIALS SCIENCE. POLYMER EDITION 2025;36:513-544. [PMID: 39291361 DOI: 10.1080/09205063.2024.2402148] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Subscribe] [Scholar Register] [Received: 07/15/2024] [Accepted: 09/04/2024] [Indexed: 09/19/2024]
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Bahadoran Z, Mirmiran P, Hosseinpanah F, Kashfi K, Ghasemi A. Nitric oxide-based treatments improve wound healing associated with diabetes mellitus. Med Gas Res 2025;15:23-35. [PMID: 39436167 PMCID: PMC11515056 DOI: 10.4103/mgr.medgasres-d-24-00020] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/12/2024] [Revised: 04/16/2024] [Accepted: 06/27/2024] [Indexed: 10/23/2024]  Open
47
Wang Z, Zhang D, Liu N, Wang J, Zhang Q, Zheng S, Zhang Z, Zhang W. A review on recent advances in polymeric microneedle loading cells: Design strategies, fabrication technologies, transdermal application and challenges. Int J Biol Macromol 2025;297:138885. [PMID: 39719236 DOI: 10.1016/j.ijbiomac.2024.138885] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 06/24/2024] [Revised: 12/11/2024] [Accepted: 12/16/2024] [Indexed: 12/26/2024]
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Ou S, Sima C, Liu Z, Li X, Chen B. Facilitation of diabetic wound healing by far upstream element binding protein 1 through augmentation of dermal fibroblast activity. Acta Diabetol 2025;62:353-365. [PMID: 39412701 DOI: 10.1007/s00592-024-02360-8] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 02/27/2024] [Accepted: 08/08/2024] [Indexed: 03/04/2025]
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Wang X, Liu M, Wu Y, Sun J, Liu L, Pan Z. Gentiopicroside targeting AKT1 activates HIF-1α/VEGF axis promoting diabetic ulcer wound healing. Front Pharmacol 2025;16:1506499. [PMID: 40078292 PMCID: PMC11897484 DOI: 10.3389/fphar.2025.1506499] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/05/2024] [Accepted: 02/10/2025] [Indexed: 03/14/2025]  Open
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Deng Q, Du F, Pan S, Xia Y, Zhu Y, Zhang J, Li C, Yu S. Activation of angiopoietin-1 signaling with engineering mesenchymal stem cells promoted efficient angiogenesis in diabetic wound healing. Stem Cell Res Ther 2025;16:75. [PMID: 39985096 PMCID: PMC11846275 DOI: 10.1186/s13287-025-04207-7] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/13/2024] [Accepted: 01/29/2025] [Indexed: 02/24/2025]  Open
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