Radiological clinical trials: Proposal of a problem-finding questionnaire to improve study success
Francesca Valdora, Bianca Bignotti, Massimo Calabrese, Nehmat Houssami, Alberto Tagliafico
Francesca Valdora, Alberto Tagliafico, Department of Experimental Medicine (DIMES) - Institute of Anatomy, University of Genoa, 16132 Genoa, Italy
Bianca Bignotti, Department of Health Sciences (DISSAL), University of Genoa, 16132 Genoa, Italy
Massimo Calabrese, Department of Radiology, UOC Senologia Diagnostica, IRCCS AOU San Martino - IST, 16132 Genoa, Italy
Nehmat Houssami, School of Public Health, Sydney Medical School, University of Sydney, Sydney, NSW 2006, Australia
Author contributions: Valdora F, Calabrese M and Tagliafico A designed the study; Valdora F and Bignotti B acquired and analysed the data; Valdora F wrote the paper; Calabrese M, Houssami N and Tagliafico A critically revised the manuscript; Calabrese M and Tagliafico A obtained funding; all authors read and approved the final manuscript.
Institutional review board statement: All studies included in this work were already approved by the respective Ethical Committee.
Clinical trial registration statement: The ASTOUND study is registered at https://clinicaltrials.gov/ct2/show/NCT02066142, and the registration identification number is NCT02066142; the TAM01 study is registered at https://clinicaltrials.gov/ct2/show/NCT01357772?term=tam01&rank=1, and the registration identification number is NCT01357772.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: None declared.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Alberto Tagliafico, MD, Assistant Professor of Human Anatomy, Department of Experimental Medicine (DIMES) - Institute of Anatomy, University of Genoa, Via De Toni 14, 16132 Genoa, Italy.
albertotagliafico@gmail.com
Telephone: +39-010-3537882 Fax: +39-010-3537885
Received: May 30, 2016
Peer-review started: June 2, 2016
First decision: July 5, 2016
Revised: November 28, 2016
Accepted: December 1, 2016
Article in press: December 1, 2016
Published online: December 26, 2016
Processing time: 204 Days and 16.6 Hours
