©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Methodol. Dec 26, 2015; 5(4): 216-222
Published online Dec 26, 2015. doi: 10.5662/wjm.v5.i4.216
Published online Dec 26, 2015. doi: 10.5662/wjm.v5.i4.216
Biomarkers of oxidative stress in erythrocytes as a function of human age
Pawan Kumar Maurya, Interdisciplinary Laboratory of Clinical Neuroscience (LINC), Department of Psychiatry, Federal University of São Paulo, São Paulo 04039-032, Brazil
Pawan Kumar Maurya, Prabhanshu Kumar, Amity Institute of Biotechnology, Amity University Uttar Pradesh, Noida 201303, India
Pranjal Chandra, Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati 781039, Assam, India
Author contributions: Maurya PK had conceived the idea; Maurya PK and Chandra P set up the frame of the review article and wrote up manuscript; Kumar P edited the entire manuscript.
Supported by Fellowship (to Pawan Kumar Maurya) (Science without Borders-Level A) from coordination of Improvement of Higher Education Personnel (CAPES), National Counsel of Technological and Scientific Development (CNPq), Brazil.
Conflict-of-interest statement: The authors report no conflicts of interest.
Correspondence to: Dr. Pranjal Chandra, MTech, PhD, Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Kamrup, Guwahati 781039, Assam, India. pchandra13@iitg.ernet.in
Telephone: +91-361-2583207 Fax: +91-361-2582249
Received: April 8, 2015
Peer-review started: April 9, 2015
First decision: June 24, 2015
Revised: September 1, 2015
Accepted: September 16, 2015
Article in press: September 18, 2015
Published online: December 26, 2015
Processing time: 250 Days and 19.5 Hours
Peer-review started: April 9, 2015
First decision: June 24, 2015
Revised: September 1, 2015
Accepted: September 16, 2015
Article in press: September 18, 2015
Published online: December 26, 2015
Processing time: 250 Days and 19.5 Hours
Core Tip
Core tip: The aim of present review is to summarize important oxidative stress biomarkers in erythrocytes during human aging. Erythrocyte membrane is rich in lipids and proteins which are easy targets of reactive oxygen species. Erythrocytes are also equipped with antioxidant defense system. Studies on biomarkers of oxidative stress are important in the establishment of reference values in different populations and in studies involving their role in different disease conditions.