Letter to the Editor: Revisiting salt restriction in hyponatremic cirrhosis - a paradigm in need of refinement?

doi:10.5662/wjm.118971

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World Journal of Methodology

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2222-0682

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Methodol. Sep 20, 2026; 16(3): 118971
Published online Sep 20, 2026. doi: 10.5662/wjm.118971

Letter to the Editor: Revisiting salt restriction in hyponatremic cirrhosis - a paradigm in need of refinement?

Cheng-Long Zou

Cheng-Long Zou, Department of Neurosurgery, Xinqiao Hospital, Army Medical University, Chongqing 400037, China

Author contributions: Zou CL completed the writing of the manuscript, data analysis, and review approval.

Supported by the National Key Research and Development Program of China, No. 2024YFC2607404.

Conflict-of-interest statement: The author reports no relevant conflicts of interest for this article.

Corresponding author: Cheng-Long Zou, PhD, Postdoctoral Fellow, Department of Neurosurgery, Xinqiao Hospital, Army Medical University, No. 83 Xinqiao Zheng Street, Shapingba District, Chongqing 400037, China. edwardzcl@pku.edu.cn

Received: January 16, 2026
Revised: March 6, 2026
Accepted: April 9, 2026
Published online: September 20, 2026
Processing time: 176 Days and 2.4 Hours

Core Tip

Core Tip: This study serves as a critical catalyst for re-evaluating a decades-old dietary dogma. It suggests that in cirrhotic patients with moderate to severe hyponatremia, automatic sodium restriction may inadvertently accelerate the path to renal injury, sarcopenia, and death. A more tailored, physiology-guided dietary strategy that prioritizes renal perfusion and nutritional preservation is urgently needed. This underscores the need for more individualized dietary strategies, particularly in this vulnerable patient population.