Methodological insights into fecal microbiota transplantation: Dissecting key approaches for success

doi:10.5662/wjm.v16.i1.108875

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 16, Issue 1

This Article

Google Scholar

Academic Content and Language Evaluation of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (98)

All Articles published online

The chart showing PDF series, HTML series, Figures (1-2) series, Tables (1-7) series.

Item

Count

PDF

HTML

Figures (1-2)

Tables (1-7)

Sum=55

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

Download

Sum=25

Mar 20, 2026 (publication date) through Feb 13, 2026

Times Cited of This Article

Times Cited (0)

Journal Information of This Article

Publication Name

World Journal of Methodology

ISSN

2222-0682

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Minireviews

World J Methodol. Mar 20, 2026; 16(1): 108875
Published online Mar 20, 2026. doi: 10.5662/wjm.v16.i1.108875

Methodological insights into fecal microbiota transplantation: Dissecting key approaches for success

Sandeep K Mundhra, Rakesh Kochhar

Sandeep K Mundhra, Department of Gastroenterology, National Institute of Medical Sciences and Research, Jaipur 303121, Rājasthān, India

Rakesh Kochhar, Department of Gastroenterology, Paras Hospital, Panchkula 134109, India

Author contributions: Kochhar R and Mundhra SK designed the overall concept and outline of the manuscript; Mundhra SK contributed to the literature review, writing and editing of the manuscript; Kochhar R supervised the literature search and writing, provided intellectual input and critically revised the manuscript; both the authors approved the paper.

Conflict-of-interest statement: The authors have no conflicts of interest to declare.

Corresponding author: Rakesh Kochhar, Professor, Department of Gastroenterology, Paras Hospital, Panchkula 134109, India. dr_kochhar@hotmail.com

Received: April 24, 2025
Revised: June 14, 2025
Accepted: September 3, 2025
Published online: March 20, 2026
Processing time: 291 Days and 23.5 Hours

Core Tip

Core Tip: Fecal microbiota transplantation (FMT) is a promising therapy for restoring gut microbiota, with established success in recurrent Clostridioides difficile infection and emerging potential in dysbiosis-related diseases. Key methodological advancements, including improved donor screening, stool processing, and novel delivery methods like capsule-based formulations and live biotherapeutic products, have improved FMT’s safety and accessibility. Despite ongoing concerns about long-term safety and efficacy, future directions such as personalized FMT, synthetic microbiota, and microbiome engineering hold significant promise.