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©The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Methodol. Mar 20, 2026; 16(1): 108611
Published online Mar 20, 2026. doi: 10.5662/wjm.v16.i1.108611
Published online Mar 20, 2026. doi: 10.5662/wjm.v16.i1.108611
High red cell distribution width as a prognostic indicator in heart failure
Sidhartha Gautam Senapati, Department of Internal Medicine, Texas Tech University Health Sciences Center El Paso, El Paso, TX 79905, United States
Azra Kothawala, Department of Medicine, Jawaharlal Nehru Medical College, Belgaum 590010, India
Vibhor Ahluwalia, Department of Internal Medicine, Nazareth Hospital, Philadelphia, PA 19152, United States
Rupak Desai, Outcomes Research, Independent Researcher, Atlanta, GA 30079, United States
Author contributions: Senapati SG contributed to the design and implementation of the study and the writing of the manuscript; Kothawala A and Ahluwalia V contributed to the writing of the manuscript; Desai R contributed to the design of the study and the revision of the manuscript; all of the authors read and approved the final version of the manuscript to be published.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Sidhartha Gautam Senapati, MD, Department of Internal Medicine, Texas Tech University Health Sciences Center El Paso, 5001 El Paso Drive, El Paso, TX 79905, United States. senapati.sidhartha36@gmail.com
Received: April 18, 2025
Revised: May 30, 2025
Accepted: August 20, 2025
Published online: March 20, 2026
Processing time: 298 Days and 8.3 Hours
Revised: May 30, 2025
Accepted: August 20, 2025
Published online: March 20, 2026
Processing time: 298 Days and 8.3 Hours
Core Tip
Core Tip: Elevated red cell distribution width serves as a simple, cost-effective prognostic marker for adverse outcomes in heart failure (HF) patients, aiding risk stratification and highlighting the need to explore its mechanistic role and therapeutic potential in HF management.