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World J Methodol. Sep 20, 2025; 15(3): 102703
Published online Sep 20, 2025. doi: 10.5662/wjm.v15.i3.102703
Third space endoscopy pulmonary complications and chylothorax post peroral endoscopic myotomy
Ahmad Madkour, Amr El-Fouly, Ahmed Ali, Karim Maurice, Ahmed El-Tawansy, Alaa Ismail, Ahmed Tawheed
Ahmed Tawheed, Amr El-Fouly, Ahmad Madkour, Department of Endemic Medicine, Faculty of Medicine, Helwan University, Cairo 11795, Egypt
Alaa Ismail, Faculty of Medicine, Helwan University, Cairo 11795, Egypt
Ahmed El-Tawansy, Department of Anesthesia and Surgical Intensive Care, Helwan University, Cairo 11795, Egypt
Karim Maurice, Department of General and Laparoscopic Surgery, Cairo University, Cairo 12613, Egypt
Ahmed Ali, Department of Gastroenterology, Mansoura International Hospital, Al Mansurah 35516, Ad Daqahlīyah, Egypt
Co-first authors: Ahmed Tawheed and Alaa Ismail.
Author contributions: Tawheed A designed the overall concept and outline of the manuscript; Tawheed A and Ismail A wrote the manuscript, they contributed equally to this article, they are the co-first authors of this manuscript; El-Tawansy A revised manuscript and provided critical points from an anesthesia point of view; Ali A followed up on the patient’s medical plan; Maurice K provided the management plan for the case; El-Fouly A and Madkour A performed the per-oral endoscopic myotomy procedure for the patient; and all authors contributed to this article and approved the final version of the manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Corresponding author: Ahmed Tawheed, MD, PhD, Department of Endemic Medicine, Faculty of Medicine, Helwan University, Ain Helwan, Cairo 11795, Egypt. ahmed.tawhid@med.helwan.edu.eg
Received: October 28, 2024
Revised: January 17, 2025
Accepted: January 23, 2025
Published online: September 20, 2025
Processing time: 131 Days and 14 Hours
Core Tip

Core Tip: In this review, we discuss a case of post-per oral endoscopic myotomy chylothorax, focusing on its management, which was carried out with the assistance of other specialties through a multidisciplinary team including a cardiothoracic surgeon, nutritionist, anesthesiologist, and, of course, gastroenterologists. We also provide a brief review of the current known data in the literature regarding post-endoscopic pulmonary complications, especially in relation to third-space endoscopic procedures such as per oral endoscopic myotomy.