Remission of type 2 diabetes mellitus: Emerging concepts and proposed diagnostic criteria

doi:10.5662/wjm.v14.i4.95210

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World Journal of Methodology

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2222-0682

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Methodol. Dec 20, 2024; 14(4): 95210
Published online Dec 20, 2024. doi: 10.5662/wjm.v14.i4.95210

Remission of type 2 diabetes mellitus: Emerging concepts and proposed diagnostic criteria

Arkiath Veettil Raveendran

Arkiath Veettil Raveendran, Department of Internal Medicine, Former Assistant Professor of Medicine, Govt. Medical College, Kozhikode 673010, Kerala, India

Author contributions: Raveendran AV designed the manuscript, collected data, and wrote and revised the manuscript.

Conflict-of-interest statement: The author declares no conflicts of interest.

Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Arkiath Veettil Raveendran, FRCP, MBBS, MD, Doctor, Department of Internal Medicine, Former Assistant Professor of Medicine, Govt. Medical College, Specialist in Internal Medicine, Badr Al Samaa, Barka, Sultanate of Oman, Kozhikode 673010, Kerala, India. raveendranav@yahoo.co.in

Received: April 4, 2024
Revised: May 18, 2024
Accepted: June 13, 2024
Published online: December 20, 2024
Processing time: 112 Days and 22.9 Hours

Core Tip

Core Tip: There is a lot of confusion regarding the criteria for remission of type 2 diabetes mellitus (T2DM), as it is described differently by various professional bodies. Therefore, we proposed criteria that will be useful for healthcare professionals worldwide for diagnosing remission. Five components should be satisfied to diagnose remission of T2DM: Previous diagnosis of T2DM; blood sugar normalization or level below the diagnostic threshold for T2DM; withdrawal of pharmacotherapy or intervention and after its washout period; improvement in the pathophysiological mechanism; and the absence of any complications, comorbidities, or disease leading to a reduction of blood sugar or its normalization.