|
1
|
Kalaivani M, Hemraj C, Varhlunchhungi V, Ramakrishnan L, Malhotra S, Gupta SK, Marwaha RK, Abraham RA, Arora M, Rawal T, Khan MA, Sinha A, Tandon N. Cardio-metabolic traits and its socioeconomic differentials among school children including metabolically obese normal weight phenotypes in India: A post-COVID baseline characteristics of LEAP-C cohort. PLoS One 2025; 20:e0321898. [PMID: 40327631 PMCID: PMC12054912 DOI: 10.1371/journal.pone.0321898] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/21/2024] [Accepted: 03/13/2025] [Indexed: 05/08/2025] Open
Abstract
BACKGROUND Cardio-metabolic risks emerge in early life and progress further in adult life. In recent times, COVID-19 pandemic aggravated risks owing to poor food security and diet quality. We aimed to assess the prevalence of cardiometabolic traits including the metabolically obese normal weight phenotype and its socioeconomic differentials in children and adolescents aged 6-19 years in India. METHODS A baseline assessment was conducted between August and December, 2022, as part of a school-based cohort study that aimed at longitudinally evaluating the anthropometric and metabolic parameters among urban children and adolescents aged 6-19 years from three public (non-fee paying) and two private (fee paying) schools in India. Private and public schools were considered as a proxy for higher and lower socioeconomic status respectively. Blood pressure and blood samples in a fasting state were obtained only from adolescents aged 10-19 years. The prevalence and its 95% confidence interval using the Clopper exact method and adjusted prevalence ratios were calculated using random-effects logistic regression models. FINDINGS Among 3888 recruited students, 1985 (51.05%) were from public schools, and 1903 (48.95%) were from private schools aged 6-19 years. The overall prevalence of underweight was 4.95% (95% CI 4.29-5.69), with a significantly higher prevalence in public schools (8.09%) than private schools (1.69%). The overall prevalences of general obesity and central obesity were 13.41% (95% CI 12.35-14.52) and 9.15% (95% CI 8.26-10.11), respectively, with significantly higher prevalence in private schools (p < 0.001). The prevalences of general and central obesity were four times (adjusted PR = 4.42, 95% CI 2.90-6.72) and eight times (adjusted PR = 8.31, 95% CI 4.82-14.35) higher, respectively, in private schools than public schools. The overall prevalence of hypertension was 7.37% (95% CI 6.33-8.51), and similar prevalences were found in public and private schools. Private school students had 2.37 times higher prevalence of impaired fasting plasma glucose (adjusted PR = 2.37, 95% CI 1.19-4.72) and 3.51 times higher prevalence of metabolic syndrome (adjusted PR = 3.51, 95% CI 1.54-8.01) than public school students. Among 2160 adolescents, 67.73% (1463) had normal body mass index. The prevalence of metabolically obese normal weight phenotype (MONW) was 42.86% (95% CI 40.30-45.44), which is higher in public [46.39% (95% CI 43.25-49.54)] than private [35.33% (95% CI 30.99-39.86)] schools (p < 0.001) with adjusted PR of 0.91 (95% CI 0.70-1.17). The most prevalent cardio-metabolic abnormality among metabolically obese normal weight phenotype was low high-density lipoprotein-c, significantly higher among adolescents from public schools (62.12% vs 52.73%, p = 0.039) than private schools. The prevalence of metabolically obese underweight (MOUW) (48/115) was 41.74% (95% CI 32.61-51.30), being higher among adolescents in public schools than private schools but not significant (p = 0.264). INTERPRETATION Effective implementation of food security measures and targeted initiatives will be crucial to mitigate the socioeconomic disparities associated with the growing burden of cardiometabolic traits. Metabolic obesity among phenotypically normal or underweight adolescents should not be overlooked but should be intervened early through novel screening criteria to prevent future cardiovascular burdens. These findings also have implications for low- and -middle income countries like India, which are undergoing a nutritional transition where socioeconomic status strongly influences cardio-metabolic traits.
Collapse
Affiliation(s)
- Mani Kalaivani
- Department of Biostatistics, All India Institute of Medical Sciences, New Delhi, India
| | - Chitralok Hemraj
- Department of Biostatistics, All India Institute of Medical Sciences, New Delhi, India
| | | | - Lakshmy Ramakrishnan
- Department of Cardiac-Biochemistry, All India Institute of Medical Sciences, New Delhi, India
| | - Sumit Malhotra
- Centre for Community Medicine, All India Institute of Medical Sciences, Delhi, India
| | - Sanjeev Kumar Gupta
- Centre for Community Medicine, All India Institute of Medical Sciences, Delhi, India
| | | | - Ransi Ann Abraham
- Department of Cardiac-Biochemistry, All India Institute of Medical Sciences, New Delhi, India
| | - Monika Arora
- HRIDAY, Green Park Extension, Green Park, Delhi, India
| | - Tina Rawal
- HRIDAY, Green Park Extension, Green Park, Delhi, India
| | - Maroof Ahmad Khan
- Department of Biostatistics, All India Institute of Medical Sciences, New Delhi, India
| | - Aditi Sinha
- Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India
| | - Nikhil Tandon
- Department of Endocrinology & Metabolism, All India Institute of Medical Sciences, Delhi, India.
| |
Collapse
|
|
2
|
Kelebie M, Kibralew G, Tadesse G, Nakie G, Ali D, Fanta B, Muche M, Fentahun S, Rtbey G, Takelle GM. Prevalence and predictors of metabolic syndrome among psychiatric patients receiving antipsychotic treatment in Africa: a systematic review and meta-analysis. BMC Psychiatry 2025; 25:433. [PMID: 40301830 PMCID: PMC12038947 DOI: 10.1186/s12888-025-06894-1] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 10/11/2024] [Accepted: 04/21/2025] [Indexed: 05/01/2025] Open
Abstract
BACKGROUND Antipsychotic medications, though essential for treating severe mental illnesses, are commonly associated with metabolic side effects that increase the risk of metabolic syndrome (MetS). These metabolic complications significantly undermine treatment adherence and contribute to adverse clinical outcomes. Despite the increasing utilization of antipsychotics in Africa, there remains a critical lack of region-specific data on the prevalence and determinants of metabolic syndrome in this population. This systematic review and meta-analysis aims to synthesize existing data on the prevalence and predictors of MetS among psychiatric patients receiving antipsychotic treatment in Africa. METHOD We looked for primary papers on PubMed/MEDLINE, Scopus, African Journal Online, PsycINFO, EMBASE, Psychiatry Online, CINAHL, Science Direct, and the Cochrane Library. We included original research articles that evaluated the prevalence of metabolic syndrome among psychiatric patients treated with antipsychotic medication. Two independent reviewers examined the articles and extracted data. The I² statistic was employed to assess statistical heterogeneity, and a random-effects meta-analysis was applied due to the observed heterogeneity. Publication bias was evaluated using a funnel plot and Egger's weighted regression test. This review has been registered with PROSPERO (ID = CRD42024558310). RESULTS This systematic review analyzed 25 primary studies encompassing a total of 4,064 participants. The pooled prevalence of metabolic syndrome among psychiatric patients receiving antipsychotic treatment in Africa was estimated at 22% (95% CI: 16.33-27.66). Female gender (OR = 3.28, 95% CI: 1.73-6.23), advanced age (OR = 1.07, 95% CI: 1.03-1.12), and elevated body mass index (OR = 5.33, 95% CI: 2.35-12.12) were identified as significant risk factors for metabolic syndrome in this population. CONCLUSION Metabolic syndrome is highly prevalent among psychiatric patients receiving antipsychotic treatment in Africa, with female sex, older age, and elevated body mass index identified as significant risk factors. These findings underscore the need for routine metabolic monitoring and timely interventions to mitigate cardiovascular risk, enhance treatment adherence, and prevent recurrence of psychiatric symptoms.
Collapse
Affiliation(s)
- Mulualem Kelebie
- Department of Psychiatry, School of Medicine, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia.
| | - Getasew Kibralew
- Department of Psychiatry, School of Medicine, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia
| | - Gebresilassie Tadesse
- Department of Psychiatry, School of Medicine, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia
| | - Girum Nakie
- Department of Psychiatry, School of Medicine, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia
| | - Dawed Ali
- Department of Psychiatry, School of Medicine, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia
| | - Biruk Fanta
- Department of Psychiatry, School of Medicine, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia
| | - Mulu Muche
- Department of Environmental Biotechnology, Institute of Biotechnology, University of Gondar, Gondar, Ethiopia
| | - Setegn Fentahun
- Department of Psychiatry, School of Medicine, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia
| | - Gidey Rtbey
- Department of Psychiatry, School of Medicine, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia
| | - Girmaw Medfu Takelle
- Department of Psychiatry, School of Medicine, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia
| |
Collapse
|
|
3
|
Liu Y, Li K, Deng Y, Li M, Gu X, Chen Y, Liu Z, Lin L, Cai L. Association of early life co-exposure to ambient PM 2.5 and O 3 with the offspring's growth within two years of age: A birth cohort study. Int J Hyg Environ Health 2025; 264:114520. [PMID: 39805190 DOI: 10.1016/j.ijheh.2025.114520] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/30/2024] [Revised: 12/03/2024] [Accepted: 01/06/2025] [Indexed: 01/16/2025]
Abstract
BACKGROUND Previous studies indicated that early life exposure to particulate matter of 2.5 μm or less (PM2.5) could impair children's growth. However, the adverse effects of maternal ozone (O3) and its interplay with PM2.5 on offspring's growth are unclear. OBJECT We aimed to investigate the independent and combined association of early-life exposure to PM2.5 and O3 with offspring growth in early childhood. METHODS This study included 632 Chinese mother-child pairs. Residential PM2.5 and O3 exposure concentrations in pregnancy and postanal 2 years were estimated by an established spatiotemporal model. During each exposure period, we also calculated the exceedance rate, the accumulative proportion of over-standard days (Exceedance standard: PM2.5>35 μg/m3, O3 > 100 μg/m3). We repeatedly measured the offspring's weight and length from birth to 2 years old and calculated the age-standardized Z-score of weight for height (WFL), body mass index (BMI), and overweight risk (BMI Z-score >85th percentile). RESULTS The adjusted generalized estimating equations showed that the concentration (an IQR increase) and exceedance rate (per 10% increase) of PM2.5 in prenatal (especially the second trimesters) and postnatal periods were associated with increased WFL, BMI Z-score, and overweight risk (βs/ORs ranging from 0.10 to 0.41/1.23 to 1.62, P < 0.05) in children within age 2 years. Although early-life exposure to O3 was not associated with growth outcomes, it showed multiplicative and additive interactions with PM2.5 on offspring growth, particularly in the 2nd trimester and early life 1000 days. The associations with WFL and BMI Z-score were greatest in the higher exceedance rates group of PM2.5 and O3 (βs ranging from 0.21 to 0.37, Pforinteraction<0.01). CONCLUSION This study demonstrated that early-life PM2.5 exposure, especially exceedance rate, was associated with increased offspring growth within 2 years of age. Furthermore, we discovered that O3 may strengthen the adverse effect of PM2.5 exposure on children's growth.
Collapse
Affiliation(s)
- Yu Liu
- Department of Maternal and Child Health, School of Public Health, Sun Yat-sen University, Guangzhou, Guangdong, China
| | - Kunying Li
- Department of Maternal and Child Health, School of Public Health, Sun Yat-sen University, Guangzhou, Guangdong, China
| | - Yuchuan Deng
- Department of Maternal and Child Health, School of Public Health, Sun Yat-sen University, Guangzhou, Guangdong, China
| | - Mengfan Li
- Department of Maternal and Child Health, School of Public Health, Sun Yat-sen University, Guangzhou, Guangdong, China
| | - Xiaonan Gu
- Department of Maternal and Child Health, School of Public Health, Sun Yat-sen University, Guangzhou, Guangdong, China
| | - Yujing Chen
- Jockey Club School of Public Health and Primary Care, The Chinese University of Hong Kong, HKSAR, China
| | - Zhaoyan Liu
- Department of Nutrition, School of Public Health, Sun Yat-Sen University, 74 Zhong Shan Road 2, Guangzhou, 510080, Guangdong, China; Guangdong Provincial Key Laboratory of Food, Nutrition and Health, School of Public Health, Sun Yat-Sen University, Guangzhou, Guangdong, China
| | - Lizi Lin
- Guangdong Provincial Engineering Technology Research Center of Environmental Pollution and Health Risk Assessment, Department of Occupational and Environmental Health, School of Public Health, Sun Yat-sen University, Guangzhou, Guangdong, China
| | - Li Cai
- Department of Maternal and Child Health, School of Public Health, Sun Yat-sen University, Guangzhou, Guangdong, China; Guangdong Provincial Key Laboratory of Food, Nutrition and Health, School of Public Health, Sun Yat-Sen University, Guangzhou, Guangdong, China.
| |
Collapse
|
|
4
|
Singh A, Karun S, Chakrabarty M, Chandra R, Singh S. Trends and determinants of obesity among ever-married women aged 15-49 in India: insights from National Family Health Surveys (NFHS 1998-2021). BMC Public Health 2025; 25:480. [PMID: 39910523 PMCID: PMC11800500 DOI: 10.1186/s12889-025-21635-5] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/05/2023] [Accepted: 01/24/2025] [Indexed: 02/07/2025] Open
Abstract
BACKGROUND Obesity has emerged as a significant public health concern in India, particularly among ever-married women of reproductive age (EMWRA). This study analyses trends in obesity among EMWRA across India and its states from 1998 to 2021 and explores the factors contributing to obesity in this group. METHODS Data from four National Family Health Survey (NFHS) rounds, spanning 1998-99 to 2019-21, were pooled to create a dataset of 1,117,433 participants. We analysed obesity trends in India and its states and assessed β- and σ-convergence in obesity rates during this period. Additionally, we examined changes in socioeconomic differentials in obesity over this period. Binary logistic regression was used to explore the association of obesity with socioeconomic, demographic, and temporal factors. RESULTS Over the study period, obesity among ever-married women of reproductive age (EMWRA) in India has shown a startling increase, tripling from 5.1% (95% CI: 4.7-5.5) in 1998-99 to 15.7% (15.4-15.9) in 2019-21. While obesity rates have surged across all states, the degree of increase varies significantly (ranging from 22.9% points in Tamil Nadu to 2.6 in Meghalaya). Presently, two prominent regions in the country exhibit high obesity rates: the southern region, including Tamil Nadu (29%), Kerala (25%), Goa (25%), and Andhra Pradesh (23%), and the northwestern region, encompassing Delhi (33%), Punjab (31%), and Haryana (24%). Moreover, the disparity in obesity rates across states has widened over time, with states initially showing higher rates experiencing a faster growth rate compared to those with lower initial rates, as highlighted by the β- and σ-convergence analyses. There was substantial variation in obesity rates across education, wealth, place of residence, and social group categories. The risk of obesity is higher among older, educated, wealthy, non-Hindu EMWRAs and TV watchers, but lower among those living in rural areas, the southern region, smaller households, and belonging to SC, ST, and OBC social groups. CONCLUSION The surge in obesity among Indian ever married women of reproductive age calls for immediate public health measures. Customized strategies, acknowledging regional differences, are vital to tackle diverse obesity rates across states. Prioritizing vulnerable groups, including the poor, uneducated, and urban populations, is critical for ensuring fair health outcomes.
Collapse
Affiliation(s)
- Aditya Singh
- Department of Geography, Banaras Hindu University, Varanasi, India
| | - Sadanand Karun
- International Institute for Population Sciences, Mumbai, Mumbai, India.
- International Institute for Population Sciences, Deonar, Mumbai, 400088, India.
| | | | - Rakesh Chandra
- Tata Institute of Social Sciences, Mumbai, Maharashtra, India
| | - Shivani Singh
- Independent Researcher, Lucknow, Uttar Pradesh, India
| |
Collapse
|
|
5
|
Sui X, Zhang L, Xu W, Meng X, Zhao Y, Gui Y, Shi H, Wang P, Zhang Y. Prenatal ozone exposure is associated with children overweight and obesity: Evidence from the Shanghai Maternal-Child Pairs Cohort. ECO-ENVIRONMENT & HEALTH 2024; 3:436-444. [PMID: 39559190 PMCID: PMC11570401 DOI: 10.1016/j.eehl.2024.04.008] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Subscribe] [Scholar Register] [Received: 11/22/2023] [Revised: 04/01/2024] [Accepted: 04/21/2024] [Indexed: 11/20/2024]
Abstract
Prenatal ozone (O3) exposure may disrupt normal offspring growth. However, epidemiological evidence that prenatal O3 exposure affects the physical development of offspring early in life is far from adequate. A total of 4909 maternal-child pairs from the Shanghai Maternal-Child Pairs Cohort were included. A high-resolution random forest model was utilized to evaluate prenatal exposure levels of O3 based on the home addresses of pregnant women. Group-based trajectory and mixed-effects models were used to assess associations between prenatal O3 exposure and physical parameters. Each 10 μg/m³ increase in O3 concentration was associated with 0.084, 0.048, and 0.082-unit increases in body mass index (BMI) for age Z score (BAZ), weight for age Z score (WAZ), and weight for length Z score (WLZ), respectively. Specifically, a 10 μg/m³ increase in O3 concentration was linked to a 1.208-fold and 1.209-fold increase in the elevated-increasing group for the BAZ and WLZ trajectories, respectively. Moreover, each 10 μg/m³ increases in prenatal O3 was associated with a 1.396-fold and 0.786-fold increase in the risk of BAZ- and length for age Z score (LAZ)-accelerated growth, respectively. Furthermore, a 10 μg/m³ increase in prenatal O3 was linked to a 1.355-fold increase in the risk of overweight and obesity (OAO). Our study revealed that prenatal O3 exposure is associated with accelerated BMI gain or decelerated body length gain in the early life of children. Prenatal O3 may also increase the risk of OAO in children for the first two years.
Collapse
Affiliation(s)
- Xinyao Sui
- Key Laboratory of Public Health Safety, Ministry of Education, School of Public Health, Fudan University, Shanghai 200032, China
- Key Lab of Health Technology Assessment, National Health Commission of the People's Republic of China, Fudan University, Shanghai 200032, China
| | - Liyi Zhang
- Key Laboratory of Public Health Safety, Ministry of Education, School of Public Health, Fudan University, Shanghai 200032, China
- Key Lab of Health Technology Assessment, National Health Commission of the People's Republic of China, Fudan University, Shanghai 200032, China
| | - Weiqing Xu
- The Maternal and Child Healthcare Institute of Pudong District, Shanghai 201200, China
| | - Xia Meng
- Key Laboratory of Public Health Safety, Ministry of Education, School of Public Health, Fudan University, Shanghai 200032, China
- Key Lab of Health Technology Assessment, National Health Commission of the People's Republic of China, Fudan University, Shanghai 200032, China
| | - Yue Zhao
- Key Laboratory of Public Health Safety, Ministry of Education, School of Public Health, Fudan University, Shanghai 200032, China
- Key Lab of Health Technology Assessment, National Health Commission of the People's Republic of China, Fudan University, Shanghai 200032, China
| | - Yuyan Gui
- Key Laboratory of Public Health Safety, Ministry of Education, School of Public Health, Fudan University, Shanghai 200032, China
- Key Lab of Health Technology Assessment, National Health Commission of the People's Republic of China, Fudan University, Shanghai 200032, China
| | - Huijing Shi
- Key Laboratory of Public Health Safety, Ministry of Education, School of Public Health, Fudan University, Shanghai 200032, China
- Key Lab of Health Technology Assessment, National Health Commission of the People's Republic of China, Fudan University, Shanghai 200032, China
| | - Pengpeng Wang
- Department of Occupational and Environmental Health, College of Public Health, Zhengzhou University, Zhengzhou 450001, China
| | - Yunhui Zhang
- Key Laboratory of Public Health Safety, Ministry of Education, School of Public Health, Fudan University, Shanghai 200032, China
- Key Lab of Health Technology Assessment, National Health Commission of the People's Republic of China, Fudan University, Shanghai 200032, China
| |
Collapse
|
|
6
|
Benítez Brito N, Pinto Robayna B, Ramallo Fariña Y, Moreno Redondo F, León Salas B, Díaz Romero C. [Cross-cultural validation of the Yale Food Addiction Scale for Children (YFAS-c) into the Spanish language to assess food addiction in the pediatric population]. SPANISH JOURNAL OF PSYCHIATRY AND MENTAL HEALTH 2024; 17:222-230. [PMID: 39710879 DOI: 10.1016/j.rpsm.2021.11.006] [Citation(s) in RCA: 1] [Impact Index Per Article: 1.0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Subscribe] [Scholar Register] [Received: 05/10/2021] [Revised: 09/16/2021] [Accepted: 11/04/2021] [Indexed: 01/25/2023]
Abstract
INTRODUCTION The scale The Yale Food Addiction Scale Children (YFAS-c) is the first measure designed to evaluate food addiction in children. However, this tool is not adapted to the Spanish language. MATERIAL AND METHODS A translation, adaptation and methodological validation of the YFAS-c tool into the Spanish language is carried out. Initially, the scale is translated and adapted through blinded and independent translators, estimating their adaptability and agreement (Cohen's Kappa). Subsequently, the questionnaire is submitted to a committee of experts to evaluate the cultural suitability, representativeness and face and content validity using the content validity ratio (CVR), its version modified by Tristán (CVR') and the Content Validity Index (CVI). Finally, linguistic comprehension is evaluated in a target sample using the Chi-square test. RESULTS Difficulty in cross-cultural adaptability of the questionnaire among translators was low (mean: 1.96, DE: 1.40; Kappa agreement: 0.32, P=.01). The evaluation of the tool by the expert committee obtained high indices: clarity (n=0.83), precision (n=0.83), comprehension (n=0.84) and content relevance (n=0.83). Of the total of 25 items, only one item presented difficulties in understanding by age groups (P=.02). CONCLUSIONS A validated version, translated and adapted to the Spanish language (S-YFAS-c) has been obtained that will be able to evaluate food addiction in Spanish-speaking children.
Collapse
Affiliation(s)
- Néstor Benítez Brito
- Dirección General de Salud Pública, Servicio Canario de la Salud, Santa Cruz de Tenerife, España; Facultad de Ciencias de la Salud, Universidad IsabelI, Burgos, España.
| | - Berta Pinto Robayna
- Área de Nutrición y Bromatología, Departamento de Ingeniería Química y Tecnología Farmacéutica, Facultad de Farmacia, Universidad de La Laguna, San Cristóbal de la Laguna, Santa Cruz de Tenerife, España
| | - Yolanda Ramallo Fariña
- Fundación Canaria Instituto de Investigación Sanitaria de Canarias (FIISC), Servicio de Evaluación del Servicio Canario de la Salud (SESCS), Las Palmas de Gran Canaria, España; Red de Investigación en Servicios de Salud en Enfermedades Crónicas (REDISSEC), España
| | - Francisco Moreno Redondo
- Área de Nutrición y Bromatología, Departamento de Ingeniería Química y Tecnología Farmacéutica, Facultad de Farmacia, Universidad de La Laguna, San Cristóbal de la Laguna, Santa Cruz de Tenerife, España
| | - Beatriz León Salas
- Fundación Canaria Instituto de Investigación Sanitaria de Canarias (FIISC), Servicio de Evaluación del Servicio Canario de la Salud (SESCS), Las Palmas de Gran Canaria, España
| | - Carlos Díaz Romero
- Área de Nutrición y Bromatología, Departamento de Ingeniería Química y Tecnología Farmacéutica, Facultad de Farmacia, Universidad de La Laguna, San Cristóbal de la Laguna, Santa Cruz de Tenerife, España
| |
Collapse
|
|
7
|
Huang Z, Tian Z, Cui J, Wang G, Chen J. Prevalence of overweight/obesity, and associated factors among adolescents aged 12 ∼ 15 in Shandong Province, China: A cross-sectional study. Prev Med Rep 2024; 45:102831. [PMID: 39193377 PMCID: PMC11347837 DOI: 10.1016/j.pmedr.2024.102831] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/09/2023] [Revised: 07/15/2024] [Accepted: 07/16/2024] [Indexed: 08/29/2024] Open
Abstract
Overweight/obesity among adolescents in Shandong Province, China, has been rising, posing significant public health challenge. Comprehensive investigation is needed to develop effective interventions. Following the Strengthening the Reporting of Observational Studies in Epidemiology guidelines, a stratified random cluster sampling approach was used from September to October 2023 across 17 cities in Shandong Province. The study included 165 middle schools, surveying 99,638 students aged 12 ∼ 15. After applying exclusion criteria, 97,356 students (97.71% effective rate) completed anthropometric measurements and questionnaires. Overweight/obesity were assessed based on national and international standards. Univariable chi-square test and multivariable logistic regression were used to analyze factors influencing overweight/obesity. In 2023, the overweight/obesity rate among 12 ∼ 15-year-olds in Shandong was 19.75%. Significant factors included sex, age, residence, family income, parental weight status and activity, mother's gestational diabetes history, birth weight, physical activity, sleep, screen time, homework, and diet. Girls, older adolescents, and those with physically active parents or who themselves engaged in over 1.5 h of daily physical activity had lower odds of being overweight/obese. Adequate sleep and frequent consumption of vegetable and fruit were also protective. Higher odds were associated with urban residence, high family income, overweight/obese parents, maternal gestational diabetes, high birth weight, excessive screen time, extensive homework, and frequent fast food consumption. Overweight/obesity in Shandong adolescents is influenced by multiple determinants. Holistic interventions addressing genetic, behavioral, and environmental factors are essential for promoting healthier lifestyles and reducing the prevalence in this demographic.
Collapse
Affiliation(s)
- Zhihao Huang
- School of Big Data and Fundamental Sciences, Shandong Institute of Petroleum and Chemical Technology, Dongying, China
| | - Zhiqi Tian
- Department of Clinical Laboratory, Shengli Oilfield Central Hospital, China
| | - Jian Cui
- School of Big Data and Fundamental Sciences, Shandong Institute of Petroleum and Chemical Technology, Dongying, China
| | - Guan Wang
- School of Big Data and Fundamental Sciences, Shandong Institute of Petroleum and Chemical Technology, Dongying, China
| | - Jiyan Chen
- School of Big Data and Fundamental Sciences, Shandong Institute of Petroleum and Chemical Technology, Dongying, China
| |
Collapse
|
|
8
|
Solomon RS, Solomon AR. Utility of anthropometry in defining overweight and obesity in urban South Indian children. J Family Med Prim Care 2024; 13:2952-2957. [PMID: 39228557 PMCID: PMC11368354 DOI: 10.4103/jfmpc.jfmpc_1656_23] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/08/2023] [Revised: 01/12/2024] [Accepted: 01/17/2024] [Indexed: 09/05/2024] Open
Abstract
Introduction Waist-based indicators of obesity are being used to detect central obesity and are predictive for metabolic syndrome (MS). The aim of the study is to assess the basic anthropometric indices in children, to determine the prevalence of overweight and obesity, and to determine the association between various waist-based measurements and body mass index (BMI). Methodology A cross-sectional study was conducted among children aged 10 to 15 years attending government corporation schools in Chennai. Basic anthropometric measurements were taken. BMI, waist circumference/height ratio (WHtR), and waist circumference/hip circumference ratio (WHR) were calculated. The percentiles (Indian reference cutoffs) were determined for waist circumference (WC) and BMI. The prevalence of overweight and obesity was determined and compared to waist-based parameters. Results Of 820 children, males constituted 47.1%. Stunting was seen in 9.8% and 7.8% were underweight. 8.2% had BMI less than the 3rd percentile. The prevalence of overweight and obese children was 9% and 3.2%, respectively, with female predominance. The majority had WC less than the 5th percentile. The prevalence of children under risk for MS based on WC >70th percentile was 4.5% and based on WHtR >0.5 was 8.2%. A significant association was identified between all waist-based anthropometric measurements to detect children at risk for MS and overweight/obese children as per BMI category. WHtR >0.5 was an indicator of overweight/obese children in logistic regression analysis. Conclusion Early identification of children at risk of MS would require a combination of BMI to detect general obesity and waist-based anthropometric measurements to identify central obesity.
Collapse
Affiliation(s)
- Ritchie S. Solomon
- Department of Pediatric Cardiology, Institute of Child Health and Hospital for Children, Egmore, Chennai, Tamil Nadu, India
| | - Adlyne R. Solomon
- Department of Endocrinology, Sri Ramachandra Medical College and Research Institute, Mount Poonamallee Road, Chennai, Tamil Nadu, India
| |
Collapse
|
|
9
|
Özer Ö, Uyhan O, Devrilmez E, Orhan İ, Bilgiç M, Uğurlu A, Tabak EY, Yüksel O, Şentürk A, Karakullukçu A, Eler N, Özcan K, Akpınar S. The relationship between attitude toward physical activity and weight gain in children and young adolescence. Front Pediatr 2024; 12:1300613. [PMID: 38774299 PMCID: PMC11106473 DOI: 10.3389/fped.2024.1300613] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 09/29/2023] [Accepted: 04/23/2024] [Indexed: 05/24/2024] Open
Abstract
Introduction The purpose of this study was to investigate the association between attitudes toward physical activity and weight gain among children and young adolescents with an additional focus on the impact of gender on these attitudes. Methods Employing a descriptive survey method, data were systematically gathered via purposive sampling from 11 specific cities in Türkiye, ensuring representation from all seven regions. A total of 3,138 students, aged between 9 and 14 years, participated in this study, with a distribution of 46% girls and 54% boys. To assess the attitudes of children and young adolescents toward physical activity, the Youth Physical Activity Attitude Scale was utilized. Height and body weight measurements were taken to determine the body mass index of participants. SPSS 26.0 software facilitated the statistical analyses, including Pearson correlation analysis to explore relationships between variables. Multivariate Analysis of Variance was employed to evaluate the impact of age, BMI, and gender on attitudes toward physical activity. Results Participants classified as normal weight exhibited a more positive attitude towards physical activity compared to their obese and overweight counterparts. Moreover, a significant gender difference emerged, with boys demonstrating significantly higher positive attitudes toward physical activity than girls. However, no significant difference was observed in negative attitudes based on gender. The study also revealed that an escalation in negative attitudes towards physical activity correlated with students being categorized as underweight, overweight, or obese, as opposed to having a normal weight status. Additionally, a statistically significant divergence in both positive and negative attitudes towards physical activity was found based on age. Specifically, the results indicated that students aged 9 and 14 exhibited lower levels of positive attitude when contrasted with their counterparts of different age groups. Conversely, in the domain of negative attitudes, students at the age of 9 scored higher than their peers in other age categories. Discussion Attitudes towards physical activity can serve as a convenient indicator and guide for assessing the effectiveness of various practices or interventions aimed at promoting physical activity, with recognition of the significant gender difference in positive attitudes among children and young adolescents.
Collapse
Affiliation(s)
- Ömer Özer
- Faculty of Sport Science, Department of Physical Education and Sport, Bandırma Onyedi Eylül University, Balıkesir, Türkiye
| | - Osman Uyhan
- Institute of Health Science, Bandırma Onyedi Eylül University, Balıkesir, Türkiye
| | - Erhan Devrilmez
- Faculty of Sport Science, Department of Physical Education and Sport, Karamanoğlu Mehmetbey University, Karaman, Türkiye
| | - İlkay Orhan
- Faculty of Sport Science, Department of Physical Education and Sport, Akdeniz University, Antalya, Türkiye
| | - Mert Bilgiç
- Faculty of Sport Science, Department of Coaching Education, Akdeniz University, Antalya, Türkiye
| | - Alkan Uğurlu
- Faculty of Sport Science, Department of Physical Education and Sport, Akdeniz University, Antalya, Türkiye
| | - Ekrem Yasin Tabak
- Institute of Social Science, Karamanoğlu Mehmetbey University, Karaman, Türkiye
| | - Oğuzhan Yüksel
- Faculty of Sport Science, Department of Recreation, Dumlupınar University, Kütahya, Türkiye
| | - Aydın Şentürk
- Faculty of Sport Science, Department of Coaching Education, Dumlupınar University, Kütahya, Türkiye
| | - Ayla Karakullukçu
- Faculty of Sport Science, Department of Sport Management, Kırıkkale University, Kırkkale, Türkiye
| | - Nebahat Eler
- School of Physical Education and Sport, Department of Coaching Education, Bülent Ecevit University, Zonguldak, Türkiye
| | - Kürşat Özcan
- Faculty of Sport Science, Department of Physical Education and Sport, Nevşehir Hacı Bektaş Veli University, Nevşehir, Türkiye
| | - Selçuk Akpınar
- Faculty of Sport Science, Department of Physical Education and Sport, Nevşehir Hacı Bektaş Veli University, Nevşehir, Türkiye
| |
Collapse
|
|
10
|
Khatun S, Ogawa M, Uchizawa A, Hoshi D, Tamai S, Momma R, Kondo E, Watanabe K, Sagayama H. Glycated hemoglobin (HbA1c) is independently associated with the bioelectrical impedance phase angle in junior sumo wrestlers: A pilot study. Physiol Rep 2024; 12:e16045. [PMID: 38740565 PMCID: PMC11090887 DOI: 10.14814/phy2.16045] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/07/2024] [Revised: 04/26/2024] [Accepted: 04/26/2024] [Indexed: 05/16/2024] Open
Abstract
The study explores the relationship between phase angle (PhA), an indicator of cellular health, and metabolic health parameters among junior sumo wrestlers in Japan. Given the demanding lifestyle and high-energy diets of sumo wrestlers that predispose them to metabolic syndrome post-retirement, this study focuses on a younger cohort. The primary aim is to evaluate if PhA could serve as an early indicator of metabolic health issues within this unique demographic. A total of 14 sumo wrestlers aged 9-17 years were assessed to determine the relationship between PhA and various metabolic markers, including glycated hemoglobin (HbA1c), using a TANITA MC-780A-N body composition analyzer and standard blood tests. Bivariate regression analysis and Pearson's correlation revealed a negative relationship between PhA and HbA1c even after adjusting for age and weight (ß = -0.496, r2 = 0.776, r = -0.756, p = 0.004). The results indicate a significant negative relationship between PhA and HbA1c levels, suggesting that lower PhA values, which indicate poorer cellular integrity, are associated with higher HbA1c levels, signifying impaired glycemic control. These findings underscore the potential of PhA as a valuable biomarker for monitoring metabolic health in young sumo wrestlers, with implications for early intervention and management strategies.
Collapse
Affiliation(s)
- Suraiya Khatun
- Doctoral Program in Sports Medicine, Graduate School of Comprehensive Human SciencesUniversity of TsukubaIbarakiJapan
| | - Miori Ogawa
- Department of PediatricsJapanese Red Cross Nasu HospitalTochigiJapan
- Institute of Health and Sports SciencesUniversity of TsukubaIbarakiJapan
| | - Akiko Uchizawa
- Institute of Health and Sports SciencesUniversity of TsukubaIbarakiJapan
- Japan Society for the Promotion of ScienceTokyoJapan
| | - Daisuke Hoshi
- Human Informatics and Interaction Research InstituteNational Institute of Advanced Industrial Science and TechnologyTsukubaIbarakiJapan
| | - Shinsuke Tamai
- Department of Sport Science and ResearchJapan Institute of Sports SciencesTokyoJapan
| | - Reiko Momma
- Department of Sport Science and ResearchJapan Institute of Sports SciencesTokyoJapan
| | - Emi Kondo
- Institute of Health and Sports SciencesUniversity of TsukubaIbarakiJapan
- Japan Society for the Promotion of ScienceTokyoJapan
| | - Koichi Watanabe
- Institute of Health and Sports SciencesUniversity of TsukubaIbarakiJapan
| | - Hiroyuki Sagayama
- Institute of Health and Sports SciencesUniversity of TsukubaIbarakiJapan
- Advanced Research Initiative for Human High Performance (ARIHHP)University of TsukubaTsukubaJapan
| |
Collapse
|
|
11
|
Nouri-Keshtkar M, Shojaei Shahrokhabadi M, Ghaheri A, Hosseini R, Ketabi H, Farjam M, Chen DG, Rezaeian M, Homayounfar R, Tahamtani Y, Totonchi M. Role of gender in explaining metabolic syndrome risk factors in an Iranian rural population using structural equation modelling. Sci Rep 2023; 13:16007. [PMID: 37749166 PMCID: PMC10520016 DOI: 10.1038/s41598-023-40485-y] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/07/2023] [Accepted: 08/10/2023] [Indexed: 09/27/2023] Open
Abstract
Many factors can lead to an increase in the prevalence of metabolic syndrome (MetS) in different populations. Using an advanced structural equation model (SEM), this study is aimed to determine the most important risk factors of MetS, as a continuous latent variable, using a large number of males and females. We also aimed to evaluate the interrelations among the associated factors involved in the development of MetS. This study used data derived from the Fasa PERSIAN cohort study, a branch of the PERSIAN cohort study, for participants aged 35 to 70 years with 10,138 males and females. SEM was used to evaluate the direct and indirect effects, as well as gender effects of influencing factors. Results from the SEM showed that in females most changes in MetS are described by waist circumference (WC), followed by hypertension (HP) and triglyceride (TG), while in males most changes in MetS are described by WC, followed by TG then fasting blood glucose (FBG). Results from the SEM confirmed the gender effects of social status on MetS, mediated by sleep and controlled by age, BMI, ethnicity and physical activity. This study also shows that the integration of TG and WC within genders could be useful as a screening criterion for MetS in our study population.
Collapse
Affiliation(s)
- Marjan Nouri-Keshtkar
- Department of Developmental Biology, University of Science and Culture, Tehran, Iran
- Department of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran
| | | | - Azadeh Ghaheri
- Department of Basic and Population Based Studies in NCD, Reproductive Epidemiology Research Center, Royan Institute, ACECR, Tehran, Iran
| | - Roya Hosseini
- Department of Basic and Population Based Studies in NCD, Reproductive Epidemiology Research Center, Royan Institute, ACECR, Tehran, Iran
- Department of Andrology, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran
| | - Hassan Ketabi
- Mobile Telecommunication Company of Iran, Tehran, Iran
| | - Mojtaba Farjam
- Noncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran
| | - Ding-Geng Chen
- College of Health Solutions, Arizona State University, Phoenix, AZ, USA
- Department of statistics, University of Pretoria, Pretoria, South Africa
| | - Mehdi Rezaeian
- Noncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran
| | - Reza Homayounfar
- Noncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran.
- National Nutrition and Food Technology Research Institute, Faculty of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
| | - Yaser Tahamtani
- Department of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran.
- Department of Basic and Population Based Studies in NCD, Reproductive Epidemiology Research Center, Royan Institute, ACECR, Tehran, Iran.
| | - Mehdi Totonchi
- Department of Genetics, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran.
| |
Collapse
|
|
12
|
Hernández-Beltrán V, Espada MC, Santos FJ, Ferreira CC, Gamonales JM. Documents Publication Evolution (1990-2022) Related to Physical Activity and Healthy Habits, a Bibliometric Review. Healthcare (Basel) 2023; 11:1669. [PMID: 37372787 DOI: 10.3390/healthcare11121669] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/10/2023] [Revised: 05/30/2023] [Accepted: 06/03/2023] [Indexed: 06/29/2023] Open
Abstract
This research aims to provide an overview of the growing number of scientific literature publications related to Physical Activity and Healthy Habits. A bibliometric analysis between 1990 and 2022 in the Web of Science was carried out, following the bibliometric analysis law, using Microsoft Excel and VosViewer Software for analysis and data processing. A total of 276 documents (262 primary studies and 14 revisions) related to the topic under study were located. The results reveal an exponential growth of scientific production by 48% between 2006 and 2022. Public Environmental Occupational Health, Kaprio, J., and the USA were the knowledge field, author, and country most productive, respectively. A great thematic diversity was found related to the most used keywords by the authors, such as "physical activity", "health habits", "exercise", and "obesity". Thus, the research related to this theme is really in an exponential phase, with great interest in the importance of physical activity and healthy habits, implying practical decisions in policies to develop programs to promote physical activity and healthy habits.
Collapse
Affiliation(s)
- Víctor Hernández-Beltrán
- Optimization of Training and Sports Performance Research Group, Faculty of Sport Science, University of Extremadura, 10005 Cáceres, Spain
| | - Mário C Espada
- Instituto Politécnico de Setúbal, Escola Superior de Educação, CIEF, CDP2T, 2914-504 Setúbal, Portugal
- Life Quality Research Centre (CIEQV-Leiria), 2040-413 Rio Maior, Portugal
- CIPER, Faculdade de Motricidade Humana, Universidade de Lisboa, 1499-002 Lisboa, Portugal
| | - Fernando J Santos
- Instituto Politécnico de Setúbal, Escola Superior de Educação, CIEF, CDP2T, 2914-504 Setúbal, Portugal
- Life Quality Research Centre (CIEQV-Leiria), 2040-413 Rio Maior, Portugal
- Faculdade de Motricidade Humana, Universidade de Lisboa, 1499-002 Lisboa, Portugal
| | - Cátia C Ferreira
- Optimization of Training and Sports Performance Research Group, Faculty of Sport Science, University of Extremadura, 10005 Cáceres, Spain
- Instituto Politécnico de Setúbal, Escola Superior de Educação, CIEF, CDP2T, 2914-504 Setúbal, Portugal
| | - José M Gamonales
- Optimization of Training and Sports Performance Research Group, Faculty of Sport Science, University of Extremadura, 10005 Cáceres, Spain
- Faculty of Health Sciences, University of Francisco de Vitoria, 28223 Madrid, Spain
| |
Collapse
|
|
13
|
Artymiak P, Żegleń M, Kowal M, Woronkowicz A, Kryst Ł. Changes in the prevalence of underweight, overweight, obesity and excessive adiposity among adolescents from Kraków (Poland) in the years 1983-2020. Am J Hum Biol 2023; 35:e23866. [PMID: 36695477 DOI: 10.1002/ajhb.23866] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/04/2022] [Revised: 01/04/2023] [Accepted: 01/09/2023] [Indexed: 01/26/2023] Open
Abstract
OBJECTIVES Improved living conditions affect lifestyles and may contribute to the increased prevalence of overweight and obesity among adolescents. The aim of the study was to analyze changes in the prevalence of underweight, overweight, obesity as well as excessive adiposity among teenagers from Kraków (Poland). METHODS The study was conducted in four series in the years: 1983, 2000, 2010, and 2020. The study group included 1759 boys and 1699 girls aged 16-18 years. body mass index (BMI) was calculated on the basis of body height and weight. Adiposity was measured by bioimpedance method. Participants were grouped according to BMI categories using Cole's cut-off points and according to adiposity based on mean and standard deviations values. The significance of the differences between cohorts was assessed by the Chi-square test. RESULTS Secular increase in the prevalence of underweight and overweight was observed among girls in most age groups. An increase in the prevalence of high body fat was also observed among 16- and 17-year-old girls - the opposite trend was noted in 18-year-old girls. Contemporary boys had an increased prevalence of overweight and obesity in each age group. CONCLUSION There was a significant increase in the prevalence of body weight abnormalities in the study population. The observed results may be related to socio-economic changes that adversely affect the lifestyle of the society. The results are also important in terms of the health of future generations and may be helpful in the development of new prevention and intervention programs.
Collapse
Affiliation(s)
- Paulina Artymiak
- Department of Anthropology, Faculty of Physical Education and Sport, University of Physical Education, Kraków, Poland
| | - Magdalena Żegleń
- Pain Research Group, Institute of Psychology, Jagiellonian University, Kraków, Poland
| | - Małgorzata Kowal
- Department of Anthropology, Faculty of Physical Education and Sport, University of Physical Education, Kraków, Poland
| | - Agnieszka Woronkowicz
- Department of Anthropology, Faculty of Physical Education and Sport, University of Physical Education, Kraków, Poland
| | - Łukasz Kryst
- Department of Anthropology, Faculty of Physical Education and Sport, University of Physical Education, Kraków, Poland
| |
Collapse
|
|
14
|
Alkhathami K, Soman A, Chandy S, Ramamoorthy B, Alqahtani B. Comparing the effects of retro and forward walking on serum adiponectin levels in obese young adults. J Taibah Univ Med Sci 2023; 18:917-925. [PMID: 36852342 PMCID: PMC9958077 DOI: 10.1016/j.jtumed.2023.01.009] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/16/2022] [Revised: 11/29/2022] [Accepted: 01/18/2023] [Indexed: 01/29/2023] Open
Abstract
Objectives Retro walking or backward walking expends greater energy and places less stress on joints compared with forward walking at a similar speed. This study conducted in obese young men was primarily aimed at comparing the effects of backward walking with forward walking on adiponectin levels. The secondary aim was to describe the effects of concomitant factors, namely C-reactive protein, body mass index (BMI), waist to height ratio, and waist to hip ratio, on adiponectin levels in obese young men. Methods In this randomized comparative study, 102 participants underwent either retro walking or forward walking treadmill training four times a week for 12 weeks before and after which adiponectin, C-reactive protein, BMI, waist to height ratio, and waist to hip ratio were measured. Comparison of the measured values before and after intervention and between the groups was done, and the influence of C-reactive protein, BMI, waist to height ratio, and waist to hip ratio on adiponectin levels was determined. Results Adiponectin levels were significantly increased (p < 0.001) and C-reactive protein, BMI, waist to height ratio, and waist to hip ratio were significantly decreased (p ≤ 0.001) post-intervention. The participants who underwent retro walking training showed a significantly higher change in C-reactive protein levels, BMI, and waist to hip ratio compared to the forward walking group (p < 0.001). Adiponectin levels were influenced by BMI (p < 0.001). Conclusion Retro walking training leads to a greater increase in adiponectin and reduction in C-reactive protein, BMI, waist to height ratio, and waist to hip ratio compared to forward walking, and adiponectin levels are influenced by BMI. Retro walking treadmill training can be preferentially used to decrease cardiovascular risk factors.
Collapse
Affiliation(s)
- Khalid Alkhathami
- Department of Health Rehabilitation, College of Applied Medical Sciences, Shaqra University, Shaqra, KSA
| | - Ajith Soman
- Department of Health Rehabilitation, College of Applied Medical Sciences, Shaqra University, Shaqra, KSA,Corresponding address: Department of Health Rehabilitation, College of Applied Medical Sciences, Shaqra University, Shaqra 11961, KSA.
| | - Sunil Chandy
- Department of Clinical Lab Science, College of Applied Medical Sciences, Shaqra University, Shaqra, KSA
| | - Baranitharan Ramamoorthy
- Department of Health Rehabilitation, College of Applied Medical Sciences, Shaqra University, Shaqra, KSA
| | - Bijad Alqahtani
- Department of Health Rehabilitation, College of Applied Medical Sciences, Shaqra University, Shaqra, KSA
| |
Collapse
|
|
15
|
Tang M, Liu M, Zhang Y, Xie R. Association of family income to poverty ratio and vibration-controlled transient elastography quantified degree of hepatic steatosis in U.S. adolescents. Front Endocrinol (Lausanne) 2023; 14:1160625. [PMID: 37033220 PMCID: PMC10079211 DOI: 10.3389/fendo.2023.1160625] [Citation(s) in RCA: 23] [Impact Index Per Article: 11.5] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 02/07/2023] [Accepted: 03/14/2023] [Indexed: 04/11/2023] Open
Abstract
INTRODUCTION Inequality in socioeconomic status plays an important role in the prevalence of metabolic diseases in adolescents. The purpose of this study was to explore the association between family income and the degree of hepatic steatosis quantified by vibration-controlled transient elastography (VCTE) among U.S. adolescents. METHODS This cross-sectional study included two cycles of the National Health and Nutrition Examination Survey (NHANES) 2017-2020. Multivariate linear regression and smoothing curve fitting were used to investigate the linear and nonlinear relationship between PIR and hepatic steatosis, respectively. Subgroup analysis and interaction tests were used to test whether this relationship was stable across groups. RESULTS Of the 1,574 adolescent participants, 456 lived in poor households and 307 lived in wealthy households. After adjusting for all covariates, PIR (Ratio of family income to poverty) was significantly negatively associated with the degree of hepatic steatosis [-4.78 (-7.39, -2.17)], and this remained stable after converting PIR to a categorical variable. In addition, this significant negative association was more pronounced in women [-7.62 (-11.38, -3.87)], non-Hispanic blacks [-7.19 (-14.43, 0.06)], Mexican Americans [-6.80 (-13.63, 0.03)], and participants with BMI >30 cm2 [-10.83 (-19.70, -1.96)]. CONCLUSIONS PIR was significantly and negatively associated with the degree of hepatic steatosis in US adolescents. Additional prospective studies are needed to confirm our findings.
Collapse
Affiliation(s)
- Meiling Tang
- Department of Pediatrics, University of South China Affiliated Nanhua Hospital, Hengyang, China
| | - Mingjiang Liu
- Department of Microsurgery, University of South China. Hengyang Affiliated Nanhua Hospital, Hengyang, China
| | - Ya Zhang
- Department of Gland Surgery, University of South China. Hengyang Affiliated Nanhua Hospital, Hengyang, China
- *Correspondence: Ya Zhang, ; Ruijie Xie,
| | - Ruijie Xie
- Department of Microsurgery, University of South China. Hengyang Affiliated Nanhua Hospital, Hengyang, China
- *Correspondence: Ya Zhang, ; Ruijie Xie,
| |
Collapse
|
|
16
|
Martínez-Navarro I, Vilchis-Gil J, Cossío-Torres PE, Hernández-Mendoza H, Klünder-Klünder M, Layseca-Espinosa E, Galicia-Cruz OG, Rios-Lugo MJ. Relationship of Serum Zinc Levels with Cardiometabolic Traits in Overweight and Obese Schoolchildren from Mexico City. Biol Trace Elem Res 2022:10.1007/s12011-022-03533-8. [PMID: 36572827 PMCID: PMC9792317 DOI: 10.1007/s12011-022-03533-8] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Figures] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 10/18/2022] [Accepted: 12/13/2022] [Indexed: 12/28/2022]
Abstract
Zinc (Zn) participates as a cofactor for many enzymes in the cellular metabolism, and its serum levels have been associated with different metabolic diseases, especially obesity (OB). Nevertheless, its associations are not clear in the children population. The objective of this study is to evaluate the association between serum Zn levels (SZn) with overweight/obesity status (OW/OB), as well as its cardiometabolic traits in a population of children in Mexico City. Anthropometrical data (body mass index z score (BMIz)), demographic variables (age and sex), and cardiometabolic traits (total cholesterol (TC), high-density lipoprotein cholesterol (HDLc), low-density lipoprotein cholesterol (LDLc), triglycerides (TG), fasting plasma glucose (FPG), and insulin) were analyzed in this cross-sectional study. SZn were measured by inductively coupled plasma mass spectrometry (ICP-MS). The population included 210 children from Mexico City (girls (n = 105) and boys (n = 105)) between ages 6 and 10 years. Normal-weight (NW) schoolchildren had higher SZn concentrations (66 µg/dL; IQR: 48 to 91) compared to OW or OB schoolchildren (61 µg/dL; IQR: 45 to 76). The data showed a significant negative association between SZn and BMIz without sex exclusion (r = - 0.181 and p = 0.009). The boy's population did not show an association between the SZn and BMIz compared to the girl's population which showed a significant negative association (r = - 0.277 and p = 0.004). In addition, other associations were found between SZn and TC (boys (r = 0.214 and p = 0.025), LDLc (boys (r = 0.213 and p = 0.029), and TG (girls (r = - 0.260 and p = 0.007)). Moreover, 38.6% of the total children in our population study had Zn deficiency (ZnD). NW schoolchildren had higher SZn concentrations compared to OW or OB schoolchildren. A diet low in Zn can be a factor to evaluate in the development of childhood OB in Mexico. However, further studies need to be performed on the children Mexican population to replicate and confirm our findings.
Collapse
Affiliation(s)
- Israel Martínez-Navarro
- Posgrado de Ciencias Basicas, Facultad de Medicina, Universidad Autónoma de San Luis Potosí, Av. Venustiano Carranza 2405, CP 78210, San Luis Potosí, S.L.P, México
| | - Jenny Vilchis-Gil
- Unidad de Investigación Epidemiológica en Endocrinología y Nutrición, Hospital Infantil de México Federico Gómez, Secretaría de Salud, CP 06720, Ciudad de Mexico, México
| | - Patricia Elizabeth Cossío-Torres
- Departamento de Salud Pública y Ciencias Médicas, Facultad de Medicina, Universidad Autónoma de San Luis Potosí, Av. Venustiano Carranza 2405, CP 78210, San Luis Potosí, S.L.P, México
| | - Héctor Hernández-Mendoza
- Instituto de Investigación de Zonas Desérticas, Universidad Autónoma de San Luis Potosí, Altair 200, CP 78377, San Luis, S.L.P, México.
- Hospital General de Soledad de Graciano Sánchez, Secretaría de Salud, Valentín Amador 1112, Soledad de Graciano Sánchez, CP 78435, San Luis Potosí, S.L.P., Mexico.
| | - Miguel Klünder-Klünder
- Dirección de Investigación, Hospital Infantil de México Federico Gómez, Secretaría de Salud, CP 06720, Ciudad de Mexico, México
| | - Esther Layseca-Espinosa
- Centro de Investigación en Ciencias de La Salud y Biomedicina, Sección de Medicina Molecular y Traslacional, Universidad Autónoma de San Luis Potosí, Avda Sierra Leona 550, CP 78210, San Luis Potosí, S.L.P, México
| | - Othir Gidalti Galicia-Cruz
- Departamento de Farmacología, Facultad de Medicina, Universidad Autónoma de San Luis Potosí, Av. Venustiano Carranza 2405, CP 78210, San Luis Potosí, S.L.P, México
| | - María Judith Rios-Lugo
- Centro de Investigación en Ciencias de La Salud y Biomedicina, Sección de Medicina Molecular y Traslacional, Universidad Autónoma de San Luis Potosí, Avda Sierra Leona 550, CP 78210, San Luis Potosí, S.L.P, México.
- Facultad de Enfermería y Nutrición, Unidad de Posgrado, Universidad Autónoma de San Luis Potosí, Avda. Niño Artillero 130, CP 78210, San Luis Potosí, S.L.P, México.
| |
Collapse
|
|
17
|
Ghaffarian-Ensaf R, Shiraseb F, Mirzababaei A, Clark CCT, Mirzaei K. Interaction between caveolin-1 polymorphism and dietary fat quality indexes on visceral adiposity index (VAI) and body adiposity index (BAI) among overweight and obese women: a cross-sectional study. BMC Med Genomics 2022; 15:258. [PMID: 36517810 PMCID: PMC9749225 DOI: 10.1186/s12920-022-01415-5] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/07/2021] [Accepted: 12/09/2022] [Indexed: 12/23/2022] Open
Abstract
BACKGROUND AND AIMS Caveolin-1 (CAV-1) in adipocyte tissue and other body parts possesses numerous biological functions. In the present study, we sought to investigate the interaction between CAV-1 polymorphism and dietary fat quality indexes on visceral adiposity index (VAI) and body adiposity index (BAI) among overweight and obese women. METHODS This study was conducted on 386 women aged 18-48 years old. Biochemical measurements were assessed by standard protocols. We used a food frequency questionnaire (FFQ) to calculate the dietary intake and the indexes of dietary fat quality intake. Anthropometric values and body composition were measured by standard methods. Finally, the CAV-1 genotype was measured using the PCR-RFLP method. RESULTS We found marginally significant differences between AA and GG genotypes of waist-to-hip ratio (WHR) (P = 0.06) and BAI (P = 0.06) of participants after adjusting for potential confounders. For dietary intakes, after adjusting with the energy intake, mean differences in biotin (P = 0.04) and total fiber (P = 0.06) were significant and marginally significant, respectively. The interaction between two risk alleles (AA) with omega-6 to omega-3 ratio (W6/W3) on BAI, after adjustment for potential confounders (age, physical activity, energy intake, education), was marginally positive (β = 14.08, 95% CI = - 18.65, 46.81, P = 0.07). In comparison to the reference group (GG), there was a positive interaction between the two risk alleles (AA) with W6/W3 ratio on VAI (β = 2.81, 95% CI = 1.20, 8.84, P = 0.06) in the adjusted model. CONCLUSIONS We found that there might be an interaction between CAV-1 genotypes with dietary quality fat indexes on VAI and BAI among overweight and obese women.
Collapse
Affiliation(s)
| | - Farideh Shiraseb
- Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences (TUMS), P.O. Box, Tehran, 14155-6117, Iran
| | - Atieh Mirzababaei
- Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences (TUMS), P.O. Box, Tehran, 14155-6117, Iran
| | - Cain C T Clark
- Centre for Intelligent Healthcare, Coventry University, Coventry, CV1 5FB, UK
| | - Khadijeh Mirzaei
- Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences (TUMS), P.O. Box, Tehran, 14155-6117, Iran.
- Food Microbiology Research Center, Tehran University of Medical Sciences, Teharn, Iran.
| |
Collapse
|
|
18
|
Kumari S, Shukla S, Acharya S. Childhood Obesity: Prevalence and Prevention in Modern Society. Cureus 2022; 14:e31640. [DOI: 10.7759/cureus.31640] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/30/2022] [Accepted: 11/18/2022] [Indexed: 11/19/2022] Open
|
|
19
|
Sorraya N, Arab A, Talebi S. The association between dietary acid load and adiposity measures among children and adolescents. BMC Pediatr 2022; 22:484. [PMID: 35962430 PMCID: PMC9375392 DOI: 10.1186/s12887-022-03541-6] [Citation(s) in RCA: 2] [Impact Index Per Article: 0.7] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 09/16/2021] [Accepted: 07/29/2022] [Indexed: 11/25/2022] Open
Abstract
Background Childhood obesity is one of the most important health problems in the present century. It is imperative to plan preventive programs through risk factor identification. The present study was conducted to examine the association between the dietary acid load (DAL) and anthropometric indices in a sample of Iranian children and adolescents. Methods In the current survey, students aged 11–18 years were recruited. To assess usual dietary intake, a validated self-administered 168-item food frequency questionnaire was used. Potential renal acid load (PRAL) and net endogenous acid production (NEAP) was used to estimate DAL. The association between DAL and anthropometric indices was evaluated using logistic regression and reported as an odds ratio (OR) with a 95% confidence interval (CI). Results In total, 456 students (267 girls), with a mean age of 14.44 years participated in the current study. After controlling for potential confounders, the PRAL was positively associated with the risk of obesity (OR = 4.56, 95% CI: 2.26, 9.17), abdominal obesity (OR = 12.64, 95% CI: 3.05, 52.27), and adiposity based on the percent of body fat (PBF) (OR = 3.58, 95% CI: 1.83, 6.99). The NEAP was also significantly associated with the risk of obesity (OR = 5.17, 95% CI: 2.56, 10.43), abdominal obesity (OR = 15.08, 95% CI: 3.35, 67.81), and adiposity based on PBF (OR = 4.53, 95% CI: 2.30, 8.92). Conclusion Our findings suggest that higher adherence to the acidogenic diet, expressed as DAL, was associated with a higher risk of general and central obesity among children and adolescents.
Collapse
Affiliation(s)
- Nasim Sorraya
- Department of Community Nutrition, School of Nutrition and Food Science, Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
| | - Arman Arab
- Department of Community Nutrition, School of Nutrition and Food Science, Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
| | - Shokoofeh Talebi
- Department of Clinical Nutrition, School of Nutrition and Food Science, Food Security Research Center, Isfahan University of Medical Sciences, Hezar Jerib street, Isfahan, 8174673461, Iran.
| |
Collapse
|
|
20
|
Obesity and COVID-19 in Children and Adolescents: Reciprocal Detrimental Influence—Systematic Literature Review and Meta-Analysis. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH 2022; 19:ijerph19137603. [PMID: 35805260 PMCID: PMC9266144 DOI: 10.3390/ijerph19137603] [Citation(s) in RCA: 31] [Impact Index Per Article: 10.3] [Reference Citation Analysis] [Abstract] [Track Full Text] [Download PDF] [Figures] [Subscribe] [Scholar Register] [Received: 05/11/2022] [Revised: 06/19/2022] [Accepted: 06/21/2022] [Indexed: 12/11/2022]
Abstract
The dramatic lifestyle changes forced by COVID-19-related lockdown promoted weight gain, with a stronger impact on obese subjects, at higher risk of severe infection. The PubMed database was searched to identify original studies assessing: (1) the extent and risk factors of lockdown-induced weight increase; and (2) the impact of obesity on the risk of hospital admission in children and adolescents. A systematic literature review and meta-analyses were performed. Twenty out of 13,986 identified records were included. A significant weight increase was reported in the majority of subjects, with no apparent gender or age differences. It was induced by a higher consumption of hypercaloric/hyperglycemic/junk food and/or the reduction of physical activity, often associated with an altered sleep–wake cycle. On the other hand, obesity increased the risk of hospitalization (OR = 4.38; 95% C.I. 1.46–13.19; p = 0.009; I2 = 96%) as compared to the normal weight population. COVID-19 and obesity represent epidemic conditions with reciprocal detrimental impact. Urgent public health interventions, targeting the various age and social strata, and involving governmental authorities, health care personnel, teachers and families are warranted to increase awareness and actively promote healthy lifestyles to contrast pediatric obesity and its detrimental consequences at a global level.
Collapse
|
|
21
|
Preliminary Results from the ACTyourCHANGE in Teens Protocol: A Randomized Controlled Trial Evaluating Acceptance and Commitment Therapy for Adolescents with Obesity. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH 2022; 19:ijerph19095635. [PMID: 35565031 PMCID: PMC9100128 DOI: 10.3390/ijerph19095635] [Citation(s) in RCA: 7] [Impact Index Per Article: 2.3] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Subscribe] [Scholar Register] [Received: 03/22/2022] [Revised: 04/27/2022] [Accepted: 05/03/2022] [Indexed: 02/06/2023]
Abstract
The study shows preliminary results of “The ACTyourCHANGE in Teens” project, a Randomized Controlled Trial aimed at evaluating the efficacy of an Acceptance and Commitment Therapy-based intervention combined with treatment as usual (ACT+TAU) compared to TAU only, for improving psychological well-being, psychological distress, experiential avoidance and fusion, emotion dysregulation, and emotional eating in a sample of 34 in-patient adolescents with obesity (Body Mass Index > 97th centile). Mixed between-within 2 × 2 repeated-measures analyses of variances (ANOVAs) were carried out to examine the changes in psychological conditions of participants over time. Moderation analyses were also conducted to test whether pre-test anxiety, depression, stress, and experiential avoidance and fusion predicted emotional eating at post-test with groups (ACT+TAU vs. TAU only) as moderators. Only a significant interaction effect (time × group) from pre- to post-test (p = 0.031) and a significant main effect of time on anxiety (p < 0.001) and emotional eating (p = 0.010) were found. Only in the TAU only group were higher levels of depression (p = 0.0011), stress (p = 0.0012), and experiential avoidance and fusion (p = 0.0282) at pre-test significantly associated with higher emotional eating at post-test. Although future replication and improvements of the study may allow us to obtain more consistent results, this preliminary evidence is actually promising.
Collapse
|
|
22
|
Hajhashemy Z, Lotfi K, Heidari Z, Saneei P. Serum Vitamin D Levels in Relation to Abdominal Obesity in Children and Adolescents: A Systematic Review and Dose-Response Meta-Analysis. Front Nutr 2022; 9:806459. [PMID: 35252295 PMCID: PMC8888413 DOI: 10.3389/fnut.2022.806459] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/31/2021] [Accepted: 01/12/2022] [Indexed: 11/28/2022] Open
Abstract
Background Findings of epidemiological studies that investigated the relationship between serum vitamin D levels and abdominal obesity were inconsistent. To evaluate the relationship between blood vitamin D levels and abdominal obesity in children and adolescents, we did a comprehensive review and dose-response meta-analysis. Methods A comprehensive search in electronic databases including Scopus, Web of Science (ISI), MEDLINE (Pubmed), EMBASE, and Google Scholar was conducted, up to May 2021, for epidemiological studies that investigated the linkage between serum vitamin D levels (as the exposure) and abdominal obesity (as the outcome) in children and adolescents. Results Combining 19 effect sizes from 14 cross-sectional studies that included 29,353 apparently healthy children illustrated that the highest vs. lowest level of serum vitamin D was related to a 35% reduced odds of abdominal obesity [odds ratio (OR): 0.65; 95% CI: 0.50, 0.84]. Linear dose-response analysis revealed that each 10 ng/ml increase in serum vitamin D levels was related to a 7% decrease in odds of abdominal obesity (OR: 0.93; 95% CI: 0.90, 0.95), only among investigations that used percentiles of waist circumference (>75th or 90th) to define the disorder (including 6,868 total subjects and 1,075 cases with abdominal obesity). Increasing serum vitamin D levels from 20 to 40 ng/ml was related to reduce odds of abdominal obesity in children. Conclusion A negative relationship between blood vitamin D levels and abdominal obesity in children and adolescents was discovered in this meta-analysis of epidemiologic studies. Among investigations that used waist circumference percentiles to define the disorder, the relationship was in a dose-response manner. To affirm this relationship, more research studies are needed, particularly using a prospective design. Systematic Review Registration https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021261319, PROSPERO 2021, identifier: CRD42021261319.
Collapse
Affiliation(s)
- Zahra Hajhashemy
- Students' Scientific Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
- Department of Community Nutrition, School of Nutrition and Food Science, Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
| | - Keyhan Lotfi
- Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran
| | - Zahra Heidari
- Department of Biostatistics and Epidemiology, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran
| | - Parvane Saneei
- Department of Community Nutrition, School of Nutrition and Food Science, Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
- *Correspondence: Parvane Saneei ;
| |
Collapse
|
|
23
|
Berube FR, Hoopes EK, D’Agata MN, Patterson F, Ives SJ, Farquhar WB, Witman MA. Subjective sleep score is associated with central and peripheral blood pressure values in children aged 7-12 years. J Sleep Res 2022; 31:e13440. [PMID: 34288196 PMCID: PMC8766862 DOI: 10.1111/jsr.13440] [Citation(s) in RCA: 1] [Impact Index Per Article: 0.3] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/19/2021] [Revised: 06/24/2021] [Accepted: 06/28/2021] [Indexed: 02/03/2023]
Abstract
Shortened and poor-quality sleep have emerged as non-traditional risk factors for the development of hypertension in adults, and it is likely these relations extend to paediatric populations when evaluating sleep subjectively. Therefore, we aimed to evaluate subjective sleep metrics and their associations with central and peripheral blood pressure (BP) values in children. We hypothesized that poor-quality sleep and short sleep duration would be associated with elevated pressures in healthy children. Subjective sleep habits and sleep duration were evaluated using the Children's Sleep Habits Questionnaire (CSHQ) in 29 children aged 7-12 years (13 male/16 female). A total sleep score was generated by summing subscale scores: a higher score indicates poorer sleep habits. Peripheral BP was measured, and central pressures were estimated using pulse wave analysis. Pearson's r correlations were used to assess relations between total sleep score, sleep duration, and sleep score subscales with BP values. Sleep score was positively associated with central and peripheral systolic pressure (r = 0.43, p = 0.02 and r = 0.41, p = 0.03, respectively), diastolic pressure (r = 0.42, p = 0.02 and r = 0.36, p = 0.05, respectively) and mean arterial pressure (r = 0.40, p = 0.03 and r = 0.36, p = 0.03, respectively). Sleep duration was negatively associated with central and peripheral diastolic pressure (r = -0.40, p = 0.03 and r = -0.41, p = 0.03, respectively). Regarding the CSHQ subscales, daytime sleepiness and parasomnias were consistently positively associated with BP values. These findings support sleep as a primordial prevention target for hypertension and the maintenance of cardiovascular health during childhood. Consideration of a variety of sleep habits using tools such as the CSHQ may provide important insights into early-life cardiovascular risk.
Collapse
Affiliation(s)
- Felicia R. Berube
- Department of Kinesiology and Applied Physiology, University of Delaware, Newark, DE
| | - Elissa K. Hoopes
- Department of Behavioral Health and Nutrition, University of Delaware, Newark, DE
| | - Michele N. D’Agata
- Department of Kinesiology and Applied Physiology, University of Delaware, Newark, DE
| | - Freda Patterson
- Department of Behavioral Health and Nutrition, University of Delaware, Newark, DE
| | - Stephen J. Ives
- Department of Health and Human Physiological Sciences, Skidmore College, Saratoga Springs, NY
| | - William B. Farquhar
- Department of Kinesiology and Applied Physiology, University of Delaware, Newark, DE
| | - Melissa A. Witman
- Department of Kinesiology and Applied Physiology, University of Delaware, Newark, DE
| |
Collapse
|
|
24
|
Al-Abri MA, Al Lawati I, Al Zadjali F. Association of elevated glycated hemoglobin and obesity with afternoon napping for more than 1 h in young and middle-aged healthy adults. Front Psychiatry 2022; 13:869464. [PMID: 36299550 PMCID: PMC9589106 DOI: 10.3389/fpsyt.2022.869464] [Citation(s) in RCA: 4] [Impact Index Per Article: 1.3] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 02/04/2022] [Accepted: 09/05/2022] [Indexed: 11/13/2022] Open
Abstract
INTRODUCTION Sleep has different patterns followed worldwide and can be influenced by social, cultural, and environmental factors. Daytime napping is commonly practiced in different parts of the world with controversial results of its effect on glucose metabolism. The current study aims to examine the association of afternoon napping and night sleep duration with metabolic derangements. METHODS This is a cross-sectional study involving young adults and middle-aged subjects. Anthropometric measurements were taken for height and weight and hip and waist ratio. Consented subjects were asked to wear actigraphy for 1 week and run their usual daily activities. Home sleep apnea testing was performed to exclude obstructive sleep apnea. Subjects had been asked to come fasting on day seven for blood collection to test for fasting glucose, glycated hemoglobin, lipid profile, and insulin. RESULTS A total of 405 subjects were involved to complete the study (52% male, 48% female). The mean age of participants was 32.8 ± 11.5 years. The study indicated that the duration of afternoon napping was significantly associated with abnormal glycated hemoglobin (HbA1c > 5.7%) (p = 0.01) and body mass index (p = 0.046) independent of age, gender, and nocturnal sleep duration. Nocturnal sleep duration was associated with increased insulin level (p = 0.04). CONCLUSION Afternoon napping is associated with an increased level of glycated hemoglobin and obesity and that may predispose to the development of type 2 diabetes mellitus.
Collapse
Affiliation(s)
- Mohammed A Al-Abri
- Department of Physiology, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, Oman
| | - Ibtisam Al Lawati
- Department of Physiology, Oman College of Health Sciences, Muscat, Oman
| | - Fahad Al Zadjali
- Department of Biochemistry, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, Oman
| |
Collapse
|
|
25
|
Longitudinal Association of Maternal Pre-Pregnancy BMI and Third-Trimester Glycemia with Early Life Growth of Offspring: A Prospective Study among GDM-Negative Pregnant Women. Nutrients 2021; 13:nu13113971. [PMID: 34836226 PMCID: PMC8619788 DOI: 10.3390/nu13113971] [Citation(s) in RCA: 5] [Impact Index Per Article: 1.3] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/09/2021] [Revised: 11/02/2021] [Accepted: 11/03/2021] [Indexed: 01/22/2023] Open
Abstract
Intrauterine modifiable maternal metabolic factors are essential to the early growth of offspring. The study sought to evaluate the associations of pre-pregnancy BMI and third-trimester fasting plasma glucose (FPG) with offspring growth outcomes within 24 months among GDM-negative pregnant women. Four hundred eighty-three mother –offspring dyads were included from the Shanghai Maternal-Child Pairs Cohort. The pregnant women were categorized into four mutually exclusive groups according to pre-pregnancy BMI as normal or overweight/obesity and third-trimester FPG as controlled or not controlled. Offspring growth in early life was indicated by the BAZ (BMI Z-score), catch-up growth, and overweight/obesity. Among those with controlled third-trimester FPG, pre-pregnancy overweight/obesity significantly increased offspring birth weight, BAZ, and risks of overweight/obesity (RR 1.83, 95% CI 1.23 to 2.73) within 24 months. Those who had uncontrolled third-trimester FPG had a reduced risk of offspring overweight/obesity within 24 months by 47%. The combination of pre-pregnancy overweight/obesity and maternal uncontrolled third-trimester FPG increased 5.24-fold risk of offspring catch-up growth within 24 months (p < 0.05). Maternal pre-pregnancy overweight/obesity and uncontrolled third-trimester glycemia among GDM-negative women both have adverse effects on offspring growth within 24 months. With the combination of increasing pre-pregnancy BMI and maternal third-trimester FPG, the possibility of offspring catch-up growth increases.
Collapse
|
|
26
|
Rouhani P, Hajhashemy Z, Saneei P. Circulating serum vitamin D levels in relation to metabolic syndrome in children: A systematic review and dose-response meta-analysis of epidemiologic studies. Obes Rev 2021; 22:e13314. [PMID: 34231300 DOI: 10.1111/obr.13314] [Citation(s) in RCA: 7] [Impact Index Per Article: 1.8] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 02/22/2021] [Revised: 04/28/2021] [Accepted: 06/07/2021] [Indexed: 01/08/2023]
Abstract
Findings from epidemiologic studies that evaluated the relationship between serum vitamin D levels and metabolic syndrome (MetS) in children were contradictory. We conducted a systematic review and meta-analysis on the relation of serum 25(OH)D levels and MetS in children. A comprehensive search was conducted in electronic databases, up to November 2020. Eleven cross-sectional studies that reported the link between circulating vitamin D levels and MetS in children were included in the analysis. Combining 11 effect sizes from 11 cross-sectional studies with 22,196 participants revealed that highest versus lowest serum vitamin D concentration was significantly associated with a 50% reduced odds of MetS in children (OR: 0.50; 95%CI: 0.39, 0.64). Subgroup analysis by study location revealed decreased odds of MetS in both non-Asian (OR: 0.45; 95%CI: 0.33, 0.63) and Asian countries (OR: 0.54; 95%CI: 0.39, 0.76) with no heterogeneity in these subgroups. When we confined the studies to those with representative populations (n = 21,611), a significant inverse association was found between highest versus lowest circulating vitamin D level and MetS (OR: 0.55; 95%CI: 0.42, 0.71). Dose-response analysis showed that each 10 ng/ml (or 25 nmol/L) in serum vitamin D was linearly related to a 12% reduced odds of MetS (OR: 0.88; 95%CI: 0.78, 0.99) in children. A nonlinear association was also detected between serum 25(OH)D and MetS. This meta-analysis revealed that circulating vitamin D concentration was inversely associated with odds of MetS in children, in a dose-response fashion. The same finding was found in the studies with representative populations.
Collapse
Affiliation(s)
- Parisa Rouhani
- Students' Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran.,Department of Community Nutrition, School of Nutrition and Food Science, Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
| | - Zahra Hajhashemy
- Students' Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran.,Department of Community Nutrition, School of Nutrition and Food Science, Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
| | - Parvane Saneei
- Department of Community Nutrition, School of Nutrition and Food Science, Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
| |
Collapse
|
|
27
|
The effect of height on estimates of the change in BMI-based prevalence of childhood obesity. Int J Obes (Lond) 2021; 45:2506-2510. [PMID: 34408256 DOI: 10.1038/s41366-021-00916-0] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 03/30/2020] [Revised: 07/06/2021] [Accepted: 07/16/2021] [Indexed: 02/06/2023]
Abstract
BACKGROUND/OBJECTIVES Body mass index (BMI, body mass/height2) is biased toward height in children. Here we investigate how change in population height affected change in BMI-based estimates of the prevalence of overweight and obesity in Australian children. SUBJECTS/METHODS Height, weight, and percent body fat (%BF) were measured at ages 8, 10, and 12 years (1855 sets of measures). Age-specific relationships between BMI and height were derived, adjusting for %BF, to estimate the degree of height bias inherent in BMI. Then, from cross-sectional measurements recorded in 1985 (N = 2388) and 1995 (N = 2148) in 8, 10, and 12 year olds, changes in overweight/obesity prevalences were calculated before and after accounting for the BMI-height bias. RESULTS Estimates of the effect of height on BMI following adjustment for %BF were similar across age groups and all were significant at p < 0.001. Referring to 12 year olds, at the same %BF for a 1% increase in height there was 0.77% (95% CI 0.55, 0.99) increase in BMI in boys, and 0.74% (0.28, 1.02) increase in girls. Between 1985 and 1995, mean height of 12-year-old boys and girls increased 3.9 and 3.2 cm, respectively. In 1985 unadjusted prevalences of combined overweight/obesity in boys and girls were 13.5% and 13.0%, respectively, and in 1995 were 24% and 24.5%. The latter values were reduced to 21.6% and 22.6% after adjusting for increased height. CONCLUSIONS Previously reported increases in childhood overweight/obesity in Australia between 1985 and 1995 were likely to be moderately overestimated as a result of increased population height; suggesting that population height be taken into account in any pediatric investigation of changes in overweight/obesity prevalence over time.
Collapse
|
|
28
|
Najjar S, Saade M, Abdalla S, AlBuhairan F. Determinants of adolescents' perceptions on access to healthcare services in the Kingdom of Saudi Arabia: Jeeluna national survey findings. BMJ Open 2021; 11:e035315. [PMID: 34675008 PMCID: PMC8532543 DOI: 10.1136/bmjopen-2019-035315] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 11/04/2019] [Revised: 10/14/2020] [Accepted: 10/19/2020] [Indexed: 11/04/2022] Open
Abstract
OBJECTIVES The study aimed at identifying the determinants of adolescents' access to healthcare services. SETTING Intermediate and secondary schools across all 13 regions in the Kingdom of Saudi Arabia (KSA) from 2011 to 2012 through the Jeeluna national school-based survey. PARTICIPANTS Intermediate and secondary school students participated in the study. A multistage, cluster, random sampling technique was used. Participants responded to a self-administered questionnaire that addressed several domains. MAIN OUTCOME MEASURE Adolescents' perception of access to healthcare services. RESULTS Twenty-five per cent of participants reported difficulty in accessing healthcare. Women, early (younger) adolescents and adolescents with three siblings were less likely to report difficulty in accessing healthcare than men, late (older) adolescents and those with fewer than three siblings. Adolescents from low-income families and those with either mental or physical illness were more likely to report difficulty in accessing healthcare than adolescents from higher income families and those without mental or physical illnesses. CONCLUSIONS Disparities in access to care exist between certain subpopulations of adolescents. Efforts are needed to support enhancing access and making it more equitable. Training for healthcare professionals and targeted health policies are necessary to improve adolescents' access to health services in the KSA. TRIAL REGISTRATION NUMBER RC08-092; King Abdullah International Medical Research Centre.
Collapse
Affiliation(s)
- Shahenaz Najjar
- Health Informatics, Arab American University, Ramallah, Palestinian Territory, Occupied
- Population Health Research Section, King Abdullah International Medical Research Center, Riyadh, Saudi Arabia
| | - Mayssa Saade
- King Abdullah International Medical Research Center, Riyadh, Riyadh, Saudi Arabia
| | - Sahar Abdalla
- Population Health Research Section, King Abdullah International Medical Research Center, Riyadh, Saudi Arabia
- Barts Cancer Institute, London, London, UK
| | - Fadia AlBuhairan
- Population Health Research Section, King Abdullah International Medical Research Center, Riyadh, Saudi Arabia
- Aldara Hospital and Medical Center, Riyadh, Riyadh, Saudi Arabia
- Johns Hopkins Bloomberg School of Public Health Center for Teaching and Learning, Baltimore, Maryland, USA
| |
Collapse
|
|
29
|
Colantonio E, de Souza FG, Botero JP, Malik N, Lofrano-Prado MC, Lambertucci AC, Prado WLD. Associations between Anthropometrics, Cardiorespiratory Fitness, and Metabolic Syndrome Components in Brazilian Adolescents with Obesity. Metab Syndr Relat Disord 2021; 20:36-42. [PMID: 34672810 DOI: 10.1089/met.2021.0064] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 11/12/2022] Open
Abstract
Purpose: To describe the presence of metabolic syndrome (MS) in Brazilian adolescents with obesity, and to compare anthropometric and cardiorespiratory fitness measurements in relation to the presence of MS. Methods: Sixty-seven adolescents (13-18 years, 36 girls) with obesity (body mass index z-score ≥2.0) were enrolled. The following were assessed for each participant: anthropometrics, body composition, lipid profile, glucose, serum insulin, insulin resistance, blood pressure (BP), and cardiorespiratory fitness. Results: The presence of MS was found in 47.76% of the sample. The following abnormal measurements were most frequently reported: waist circumference (WC) (100.0%), BP (85.07%), and triglycerides (TG) (50.75%). Boys with obesity were more likely to meet MS criteria when compared to girls (P = 0.040; odds ratio = 2.80 [1.04-7.56]). Conclusion: The presence of MS in Brazilian adolescents with obesity in this study was 47.76%. Among this sample, the most frequently reported MS variables above the established cutoffs were WC (100%), followed by altered BP (85%) and TG (50%). These data further support previously published studies that low levels of cardiorespiratory fitness may increase the risk of MS among adolescents with obesity.
Collapse
Affiliation(s)
- Emilson Colantonio
- Department of Movement Sciences, Federal University of São Paulo-UNIFESP, Santos, Brazil
| | | | - João Paulo Botero
- Department of Movement Sciences, Federal University of São Paulo-UNIFESP, Santos, Brazil
| | - Neal Malik
- Department of Health Science and Human Ecology, California State University-San Bernardino, San Bernardino, California, USA
| | | | | | - Wagner Luiz do Prado
- Department of Kinesiology, California State University-San Bernardino, San Bernardino, California, USA
| |
Collapse
|
|
30
|
Diagnostic Performance and Appropriate Cut-Offs of Different Anthropometric Indicators for Detecting Children with Overweight and Obesity. BIOMED RESEARCH INTERNATIONAL 2021; 2021:1608760. [PMID: 34568486 PMCID: PMC8457951 DOI: 10.1155/2021/1608760] [Citation(s) in RCA: 1] [Impact Index Per Article: 0.3] [Reference Citation Analysis] [Abstract] [Track Full Text] [Download PDF] [Figures] [Subscribe] [Scholar Register] [Received: 04/24/2021] [Revised: 07/29/2021] [Accepted: 08/07/2021] [Indexed: 12/12/2022]
Abstract
In the clinical settings, different anthropometric indicators like neck circumference (NC), waist circumference (WC), midupper arm circumference (MUAC), waist-to-height ratio (WHtR), and arm-to-height ratio (AHtR) have been suggested for evaluating overweight and obesity in children. The comparative ability of these indicators in Pakistan is yet unknown. This study is aimed at examining the validity of different anthropometric indicators of overweight and obesity simultaneously and at determining their superlative cut-off values that would correctly detect overweight and obesity in children. For this purpose, the dataset of anthropometric measurements height, weight, WC, MUAC, and NC of 5,964 Pakistani children, aged 5-12 years collected in a cross-sectional multiethnic anthropometric survey (MEAS), was used. Receiver operating characteristic (ROC) curve analysis was performed to assess the validity of different anthropometric indicators. The most sensitive and specific cut-off points, positive and negative predictive values of each indicator were also calculated. The results of the ROC curve indicated that all the studied indicators had a good performance but the indicators AHtR and WHtR had the highest value of the area under the curve (AUC) for the screening of children with overweight and obesity (AUC > 0.80). In the overall sample, AHtR, WHtR, MUAC, WC, and NC cut-off points indicative of overweight, in both boys and girls, were 0.14, 0.46, 18.41 cm, 62.86 cm, and 26.36 cm and 0.14, 0.47, 18.16 cm, 64.39 cm, and 26.54 cm, respectively; the corresponding values for obesity were 0.14, 0.47, 18.67 cm, 62.10 cm, and 26.36 cm and 0.14, 0.48, 20.19 cm, 64.39 cm, and 25.27 cm. We concluded that the sex-specific cut-off points for AHtR, WHtR, MUAC, WC, and NC can be used to diagnose overweight and obesity in Pakistani children.
Collapse
|
|
31
|
Langarizadeh M, Sadeghi M, As'habi A, Rahmati P, Sheikhtaheri A. Mobile apps for weight management in children and adolescents; An updated systematic review. PATIENT EDUCATION AND COUNSELING 2021; 104:2181-2188. [PMID: 33573915 DOI: 10.1016/j.pec.2021.01.035] [Citation(s) in RCA: 18] [Impact Index Per Article: 4.5] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Subscribe] [Scholar Register] [Received: 04/24/2020] [Revised: 01/28/2021] [Accepted: 01/29/2021] [Indexed: 06/12/2023]
Abstract
OBJECTIVE Considering inconclusive data regarding the possible effects of mobile applications on anthropometric measures (e.g. body mass index (BMI), body weight, waist circumference, fat mass) and physical activity (e.g. steps or METS) in paediatric subjects, the present systematic review was conducted to clarify this issue. METHODS Online databases including PubMed, Scopus, ISI Web of Science, Embase, and Ovid were searched, and also a hand search through Google Scholar, PsycINFO, and grey literature was done up to December 2020 to find all relevant studies. RESULTS Nine studies were included in this review (n = 978 participants). Five of the studies utilized a mobile app as an independent intervention. Using mobile applications resulted in a lower body mass index in two studies, while only one study reported a decrease in body weight. Besides, significant improvement in physical activity as evidenced by higher step count was reported by only one study. CONCLUSION Nevertheless, the findings from these primary studies, although slightly mixed, provide support for further research with the implementation of mobile apps as an additional approach for combating childhood obesity. PRACTICE IMPLICATIONS We recommend to raise attention towards and interest in the mobile app for childhood obesity prevention and treatment.
Collapse
Affiliation(s)
- Mostafa Langarizadeh
- Health Management and Economics Research Center, School of Health Management and Information Sciences, Iran University of Medical Sciences, Tehran, Iran.
| | - Malihe Sadeghi
- Department of Health Information Management, School of Health Management and Information Sciences, Iran University of Medical Sciences, Tehran, Iran; Health Information Technology Department, School of Allied Medical Sciences, Semnan University of Medical Sciences, Semnan, Iran.
| | - Atefeh As'habi
- Food Safety Research Center (Salt), Semnan University of Medical Sciences, Semnan, Iran; Department of Nutrition, School of Nutrition and Food Sciences, Semnan University of Medical Sciences, Semnan, Iran.
| | - Pakzad Rahmati
- Department of Health Information Management, School of Health Management and Information Sciences, Iran University of Medical Sciences, Tehran, Iran.
| | - Abbas Sheikhtaheri
- Health Management and Economics Research Center, School of Health Management and Information Sciences, Iran University of Medical Sciences, Tehran, Iran.
| |
Collapse
|
|
32
|
Kumar P, Srivastava S, Mishra PS, Mooss ETK. Prevalence of pre-diabetes/type 2 diabetes among adolescents (10-19 years) and its association with different measures of overweight/obesity in India: a gendered perspective. BMC Endocr Disord 2021; 21:146. [PMID: 34233661 PMCID: PMC8261995 DOI: 10.1186/s12902-021-00802-w] [Citation(s) in RCA: 3] [Impact Index Per Article: 0.8] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 07/24/2020] [Accepted: 06/21/2021] [Indexed: 12/13/2022] Open
Abstract
BACKGROUND The International Diabetes Federation (IDF) estimated that 1.1 million children and adolescents aged 14-19 years are living with diabetes. Diabetes is a chronic, progressive disease characterized by elevated levels of blood glucose. It is also recognized as a complex disease that affects people of different ages due to different causes. The present study aims to estimate the prevalence of pre-diabetes/diabetes at the national level. Additionally, the respective study determines the factors associated with pre-diabetes/diabetes conditions among adolescents at the national level. METHODS The data for this study was carried out from the Comprehensive National Nutrition Survey (CNNS), the first-ever nationally representative nutrition survey of children and adolescents in India. The study used a sample size of 17,865 adolescent boys and 17,965 adolescent girls for the analysis. Descriptive statistics, bivariate analysis, and logistic regression analysis were done to carve out the results. RESULTS The prevalence of pre-diabetes/diabetes was 12.3% and 8.4% among adolescent boys and girls in India, respectively. Body mass index and Subscapular skinfold thickness were the two most important predictors of pre-diabetes/diabetes among adolescents. Further, physical activities show a negative association with pre-diabetes/diabetes. Moreover, interaction models in the present study clearly reveal the fact that adolescent girls were less likely to suffer from pre-diabetes/diabetes than adolescent boys. Additionally, it was found that the prevalence of pre-diabetes/diabetes was high among adolescent girls from lower socio-economic strata. CONCLUSION The high prevalence of pre-diabetes and diabetes among adolescents portrayed serious public health concern in India. As body mass index and Subscapular skinfold thickness were positively associated with pre-diabetes/diabetes conditions among adolescents. Therefore, effective approaches are needed to be taken to tackle these pre-diabetes/diabetes conditions among adolescents and especially among adolescent boys.
Collapse
Affiliation(s)
- Pradeep Kumar
- International Institute for Population Sciences, Mumbai, Maharashtra 400088 India
| | - Shobhit Srivastava
- International Institute for Population Sciences, Mumbai, Maharashtra 400088 India
| | | | | |
Collapse
|
|
33
|
Zorrilla-Revilla G, Rodrigues D, Machado-Rodrigues AM, Mateos A, Rodríguez J, Padez C. Sex-specific differences in somatic investment and strategies of physical activity among Portuguese schoolchildren. Am J Hum Biol 2021; 34:e23626. [PMID: 34076323 DOI: 10.1002/ajhb.23626] [Citation(s) in RCA: 1] [Impact Index Per Article: 0.3] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/18/2021] [Revised: 05/21/2021] [Accepted: 05/22/2021] [Indexed: 12/13/2022] Open
Abstract
OBJECTIVES Physical activity (PA) is required for healthy growth, development, and maturation and plays an important role in the prevention of overweight and obesity in childhood and adolescence. Sex-differences in PA levels are well documented, with boys spending more time in PA, especially in moderate-to-vigorous activities. Following the Life History Theory, our aim is to study if PA affects the fat tissues increases during childhood and juvenile phases in both sexes. METHODS Time spent in sedentary, light, and moderate-to-vigorous PA levels were measured in a sample of 415 Portuguese children and juveniles (207 females/208 males; aged 6-11 years), using an accelerometer for 7 days. Skinfolds related with body fat were objectively collected and socioeconomic status factors were reported using a parental questionnaire. RESULTS The outcomes show that girls' and boys' fat variables increased during the end of the childhood and the juvenile phase. However, these variables were differently affected by PA. Girls increased fat variables with the sedentary activity while boys decreased fat variables with moderate-to-vigorous PA. Alike, active boys but not girls reduced the fat increase tendency with age. CONCLUSIONS Although both sexes displayed a general fat increment with age, moderate-to-vigorous PA dampens the increase only in boys. In fact, active girls increased body fat in the same manner as non-active girls. From an evolutionary perspective, it could explain sex-specific somatic strategies related to future reproduction or, with future mating and intrasexual competition.
Collapse
Affiliation(s)
| | - Daniela Rodrigues
- CIAS - Research Centre for Anthropology and Health, University of Coimbra, Coimbra, Portugal.,Department of Life Sciences, University of Coimbra, Coimbra, Portugal
| | - Aristides M Machado-Rodrigues
- CIAS - Research Centre for Anthropology and Health, University of Coimbra, Coimbra, Portugal.,High School of Education, Polytechnic Institute of Viseu, Viseu, Portugal
| | - Ana Mateos
- National Research Center on Human Evolution, CENIEH, Burgos, Spain
| | - Jesús Rodríguez
- National Research Center on Human Evolution, CENIEH, Burgos, Spain
| | - Cristina Padez
- CIAS - Research Centre for Anthropology and Health, University of Coimbra, Coimbra, Portugal.,Department of Life Sciences, University of Coimbra, Coimbra, Portugal
| |
Collapse
|
|
34
|
Debeila S, Modjadji P, Madiba S. High prevalence of overall overweight/obesity and abdominal obesity amongst adolescents: An emerging nutritional problem in rural high schools in Limpopo Province, South Africa. Afr J Prim Health Care Fam Med 2021; 13:e1-e9. [PMID: 34082550 PMCID: PMC8182488 DOI: 10.4102/phcfm.v13i1.2596] [Citation(s) in RCA: 13] [Impact Index Per Article: 3.3] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Journal Information] [Subscribe] [Scholar Register] [Received: 06/04/2020] [Revised: 02/02/2021] [Accepted: 02/02/2021] [Indexed: 01/22/2023] Open
Abstract
BACKGROUND As the gap in nutritional profiles between urban and rural rapidly reduces because of nutrition transition, rural adolescents are likely to engage in urban lifestyle behaviours. AIM The study determined the prevalence of overweight/obesity amongst adolescents in rural high schools and the association with selected factors. SETTING Fetakgomo Municipality in rural Limpopo Province, South Africa. METHODS A cross-sectional study was conducted amongst 378 adolescents selected through multistage sampling from high schools. Data collected were socio-demography, nutritional knowledge, dietary practices and anthropometry. The International Obesity Task Force age and sex-specific body mass index (BMI) cut-off values were used to determine overweight/obesity, whilst adult BMI cut-off values were used for those ≥ 18 years. Waist-to-height ratio (WHtR) greater than 0.5 indicated abdominal obesity, as well as waist circumference (WC) and waist-to-hip ratio (WHR) above the cut-off values. RESULTS The proportion of overweight/obesity amongst adolescents was 35%, whilst 25% had abdominal obesity by WHR and 21% by WHtR. Multivariate logistic regression showed that being a girl (AOR = 2.9, 95% CI: 1.74-4.85), older adolescent (AOR = 3.1, 95% CI: 1.57-6.29) and living in a household with employed adults (AOR = 2.3, 95% CI: 1.19-4.51) were associated with increased odds of being overweight/obese. Eating breakfast was associated with reduced odds of being overweight/obese (AOR = 0.6, 95% CI: 0.34-0.97). CONCLUSION Overweight/obesity and abdominal obesity amongst adolescents were more prevalent than underweight. The Integrated School Health Programme should have clear guidelines on food items served and sold at schools.
Collapse
Affiliation(s)
- Sego Debeila
- Department of Public Health, School of Health Care Sciences, Sefako Makgatho Health Sciences University, Ga-Rankuwa.
| | | | | |
Collapse
|
|
35
|
Garfein J, Flannagan KS, Rittman D, Ramirez-Zea M, Villamor E. Leukocyte telomere length is inversely associated with a metabolic risk score in Mesoamerican children. Am J Hum Biol 2021; 34:e23596. [PMID: 33720476 DOI: 10.1002/ajhb.23596] [Citation(s) in RCA: 1] [Impact Index Per Article: 0.3] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/25/2020] [Revised: 02/23/2021] [Accepted: 02/27/2021] [Indexed: 12/19/2022] Open
Abstract
OBJECTIVE Leukocyte telomere length (LTL) may be involved in the etiology of the metabolic syndrome (MetS). We examined the associations of LTL with MetS and its components among Mesoamerican children and their adult parents, in a region where MetS prevalence is high. METHODS We conducted a cross-sectional study of 151 children aged 7-12 years and 346 parents from the capitals of Belize, Honduras, Nicaragua, Costa Rica, Panama, and Chiapas State, Mexico. We quantified LTL by qPCR on DNA extracted from whole blood. In children, we created an age- and sex-standardized metabolic risk score using waist circumference (WC), the homeostasis model of insulin resistance (HOMA-IR), blood pressure, serum high-density lipoprotein (HDL) cholesterol, and serum triglycerides. In adults, MetS was defined according to the National Cholesterol Education Program's Adult Treatment Panel III definition. We estimated mean differences in metabolic risk score and prevalence ratios of MetS across quartiles of LTL using multivariable-adjusted linear and Poisson regression models, respectively. RESULTS In children, every 1 LTL z-score was related to an adjusted 0.05 units lower (95% CI: -0.09, -0.02, P = 0.005) MetS risk score, through WC, HOMA-IR, and HDL. Among adults, LTL was not associated with MetS prevalence; however, every 1 LTL z-score was associated with an adjusted 34% lower prevalence of high fasting glucose (95% CI: 3%, 55%, p = .03). CONCLUSIONS Among Mesoamerican children, LTL is associated with an improved metabolic profile; among adults, LTL is inversely associated with the prevalence of high fasting glucose.
Collapse
Affiliation(s)
- Joshua Garfein
- Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan, USA
| | - Kerry S Flannagan
- Eunice Kennedy Shriver National Institute of Child Health and Development, Rockville, Maryland, USA
| | - Danielle Rittman
- Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan, USA
| | - Manuel Ramirez-Zea
- INCAP Research Center for the Prevention of Chronic Diseases (CIIPEC), Institute of Nutrition of Central America and Panama, Guatemala City, Guatemala
| | - Eduardo Villamor
- Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan, USA
| | | |
Collapse
|
|
36
|
Decomposition of socioeconomic inequality in growth disorders to its determinants in pediatric population: the CASPIAN IV study. J Diabetes Metab Disord 2021; 20:467-476. [PMID: 34222071 DOI: 10.1007/s40200-021-00767-6] [Citation(s) in RCA: 3] [Impact Index Per Article: 0.8] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 09/16/2020] [Accepted: 02/08/2021] [Indexed: 10/22/2022]
Abstract
Purpose The current study aims to evaluate socioeconomic inequality in growth disorders and its determinants in Iranian children and adolescents. Methods In this nationwide cross-sectional survey, 14,880 students aged 6-18 years were selected through multistage cluster sampling method from urban and rural areas of 30 provinces of Iran in 2011. Socioeconomic status (SES) was calculated using principle component analysis. Socioeconomic inequality in growth disorders (including; underweight, excess weight, overweight, general obesity, abdominal obesity, and short stature) was assessed using concentration index (C) and slope index of inequality (SII). The Oaxaca Blinder decomposition method was used to determine determinants of this inequality. Results Totally, 13,486 students participated in this study (participation rate: 90.6%), comprising 50.8% boys and 75.6% urban inhabitants. Their mean age was 12.47 ± 3.36 years with no significant gender difference. The prevalence of excess weight, overweight, and general and abdominal obesity increased linearly as SES increased, and the prevalence of underweight and short stature decreased linearly as SES increased. The C index for underweight and short stature was negative, which suggests that inequality was in favor of high SES groups, and regarding overweight, excess weight, general and abdominal obesity, the index was positive, indicating that inequality was in favor of in low SES groups. Conclusion Our findings show a considerable inequality in prevalence of growth disorders in Iranian children and adolescents. These findings provide practical information for health policies and programs.
Collapse
|
|
37
|
Hajihashemi P, Azadbakht L, Hashemipour M, Kelishadi R, Saneei P, Esmaillzadeh A. Whole grain intake favorably affects blood glucose and serum triacylglycerols in overweight and obese children: A randomized controlled crossover clinical trial. Nutrition 2021; 87-88:111200. [PMID: 33744640 DOI: 10.1016/j.nut.2021.111200] [Citation(s) in RCA: 4] [Impact Index Per Article: 1.0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/03/2020] [Revised: 01/23/2021] [Accepted: 02/01/2021] [Indexed: 12/23/2022]
Abstract
OBJECTIVES The aim of this study was to determine the effects of whole grain consumption on the metabolic profiles of overweight or obese children. METHODS This was a randomized crossover clinical trial with 44 overweight or obese girls. After a 2-wk run-in period, girls were randomly assigned to either intervention or control groups. Participants in the intervention group were asked to obtain 50% of their grain servings from whole grain foods each day for 6 wk. Those in the control group were asked not to consume any of these foods. A 4-wk washout period was applied following which participants were crossed over to the alternate arm. Fasting blood samples were taken before and after each phase of study. RESULTS Mean (± SD) age and body mass index was 11.2 ± 1.49 y and 23.5 ± 2.5 kg/m2, respectively. Mean whole grain intake in intervention and control groups throughout the study was 26.5 and 3.7 g/d, respectively (P = 0.01). Whole grain consumption resulted in lower concentrations of plasma glucose (changes from baseline in intervention group: -0.10 versus 0.21 mmol/L in control group, P = 0.01), serum triacylglycerols (changes from baseline in intervention group: -0.18 versus 0.08 mmol/L in control group, P = 0.01) and higher concentrations of serum high-density lipoprotein cholesterol (changes from baseline in intervention group: 0.16 versus -0.14 mmol/L in control group, P = 0.05) after 6 wk of intervention. No effects of whole grain intake on serum concentrations of total- and low-density lipoprotein cholesterol or on blood pressure were found. CONCLUSION This study provided evidence supporting the beneficial effects of whole grain foods on serum concentrations of glucose, triacylglycerols and high-density lipoprotein cholesterol in overweight children.
Collapse
Affiliation(s)
- Parisa Hajihashemi
- Department of Community Nutrition, School of Nutrition and Food Science, Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
| | - Leila Azadbakht
- Department of Community Nutrition, School of Nutrition and Food Science, Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran; Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran
| | - Mahin Hashemipour
- Pediatrics Department, Faculty of Medicine and Child Growth and Development Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
| | - Roya Kelishadi
- Pediatrics Department, Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-Communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran
| | - Parvane Saneei
- Department of Community Nutrition, School of Nutrition and Food Science, Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
| | - Ahmad Esmaillzadeh
- Department of Community Nutrition, School of Nutrition and Food Science, Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran; Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran.
| |
Collapse
|
|
38
|
The effects of whole grain intake on anthropometric measures in overweight and obese children: a crossover randomised clinical trial. Br J Nutr 2021; 126:1459-1465. [DOI: 10.1017/s000711452100026x] [Citation(s) in RCA: 1] [Impact Index Per Article: 0.3] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 01/22/2023]
Abstract
Abstract
Whole-grain foods have been reported to affect body weight and satiety. However, we are aware of no study in this regard among children. The present study aimed to determine the effects of whole grain consumption on anthropometric measures in overweight or obese children. In this randomised crossover clinical trial, forty-four overweight or obese girls participated. After a 2-week run-in period, subjects were randomly assigned to either intervention (n 44) or non-intervention (n 44) groups. Subjects in the intervention group were given a list of whole-grain foods and were asked to obtain half of their grain servings from these foods each day for 6 weeks. Individuals in the non-intervention group were asked not to consume any of these foods. A 4-week washout period was applied. Then, participants were crossed over to the alternate arm. The measurements were done before and after each phase. Mean age, weight and BMI of participants were 11·2 (sd 1·49) years, 51·2 (sd 10·2) kg and 23·5 (sd 2·5) kg/m2, respectively. Despite the slight reduction in weight and BMI, there were no significant differences in changes in these anthropometric measures. We found a significant effect of whole grain intake on waist circumference (−2·7 v. 0·3 cm, P = 0·04). No significant changes in hip circumference were observed. Changes in the prevalence of overweight, obesity and abdominal obesity were not significantly different. This study indicated a beneficial effect of whole-grain foods on waist circumference in overweight children; however, these foods did not influence weight and BMI.
Collapse
|
|
39
|
A systematic review on the association of month and season of birth with future anthropometric measures. Pediatr Res 2021; 89:31-45. [PMID: 32353858 DOI: 10.1038/s41390-020-0908-4] [Citation(s) in RCA: 8] [Impact Index Per Article: 2.0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 09/04/2019] [Accepted: 03/30/2020] [Indexed: 01/09/2023]
Abstract
BACKGROUND Prenatal factors might have some health impacts later in life. This study aims to systematically review the current literature on the association between season and month of birth with birth weight as well as with weight status in childhood. METHODS The search process was conducted in electronic databases, including papers published until April 2019 in ISI Web of Science, PubMed, Scopus, and Google Scholar. The following search strategy was used with MeSH terms: ("Seasons"[Mesh]) AND ("Obesity"[Mesh] OR "Pediatric Obesity"[Mesh] OR "Obesity, Abdominal"[Mesh] OR "Overweight"[Mesh] OR "Birth Weight"[Mesh] OR "Body Height"[Mesh]). After the selection process, 50 papers were included in this systematic review. RESULTS This review showed that individuals who are born in cold season (winter month) have higher body mass index (BMI) and weight in childhood. Birth in March was associated with lower weight and BMI in boys according to most studies. All studies, except one of them, showed that season/month of birth was not associated with birth weight. CONCLUSIONS This systematic review confirms a relationship between season and month of birth with birth weight and body size in childhood; however, the impact of confounding factors, for example, vitamin D status, should be considered in the underlying pathway of this association. IMPACT The results provide evidence for the effect of season and month of birth on body size in childhood. Our systematic review suggests that there is no pattern between birth weight and season/month of birth, and the occurrence of low birth weight was more frequent among infants who were born in summer than others. Further research should focus on identifying the impact of confounding factors, for example, vitamin D status in the underlying pathway of this association. There was response to the controversial findings about the effect of environment factors, such as season and month of birth, and future anthropometric indices, such as obesity, weight, height, and birth weight. Obesity is a complex and multifactorial disorder; the findings of the current study would be useful in determining the relationship pathway between the season and the month of birth with other underlying factors for childhood obesity.
Collapse
|
|
40
|
Patnaik N. Study the effect of increased maternal BMI on foetal outcome: A prospective observational study. J Family Med Prim Care 2020; 9:5906-5908. [PMID: 33681017 PMCID: PMC7928135 DOI: 10.4103/jfmpc.jfmpc_1104_20] [Citation(s) in RCA: 1] [Impact Index Per Article: 0.2] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Journal Information] [Subscribe] [Scholar Register] [Received: 06/06/2020] [Revised: 09/09/2020] [Accepted: 10/06/2020] [Indexed: 11/04/2022] Open
Abstract
Aim To study the effect of increased maternal BMI on fetal outcome. Materials and Methods The present descriptive cross-sectional study entitled was conducted in the Department of Obstetrics and Gynecology. The study includes 100 subjects who have taken antenatal care at the hospital. Descriptive statistics included computation of percentages, means and standard deviations were calculated using SPSS version 20. Results Mean age was 27.21 years, mean BMI (kg/m2) was 27.49 and mean weight gain was 7.14 kgs. Most common neonatal complication was Low Birth Weight (7%) followed by Meconium Aspiration Syndrome (6%), Sepsis (6%). Neonatal death was observed among 5% subjects and still birth was reported among 4%. Conclusion Present study confirmed that maternal obesity is associated with an increased risk of neonatal complications like Low Birth Weight, Meconium Aspiration Syndrome and Sepsis.
Collapse
Affiliation(s)
- Nabnita Patnaik
- Department of Obstetrics and Gynaecology, AIIMS, Bibinagar, Telangana, India
| |
Collapse
|
|
41
|
Asif M, Aslam M, Wyszyńska J, Altaf S, Ahmad S. Diagnostic Performance of Neck Circumference and Cut-off Values for Identifying Overweight and Obese Pakistani Children: A Receiver Operating Characteristic Analysis. J Clin Res Pediatr Endocrinol 2020; 12:366-376. [PMID: 32295325 PMCID: PMC7711643 DOI: 10.4274/jcrpe.galenos.2020.2019.0212] [Citation(s) in RCA: 11] [Impact Index Per Article: 2.2] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Indexed: 12/25/2022] Open
Abstract
OBJECTIVE Neck circumference (NC) is considered to be an alternative screening method for obesity. The aims were: (1) to examine the correlation between body mass index (BMI) and NC; and (2) to determine diagnostic performance including the best cut-off values of NC for identification of overweight and obese Pakistani children. METHODS The study sample was 7,921 children, aged 5-14 years, by cross-sectional survey carried-out in four major cities of Pakistan. Receiver operating characteristic analysis was used to investigate the diagnostics performance of NC and to determine the optimal cut-off points for identifying children with overweight and obesity. RESULTS The mean of each anthropometric variable (i.e., height, weight, BMI and NC) increased with age in both sexes. In the whole sample, NC had a strong positive correlation (r=0.61, p<0.01) with BMI. NC optimal cut-off points for identifying overweight and obesity in Pakistani boys ranged between 25.00 to 30.35 cm and the corresponding values for the girls were 24.00 to 31.62 cm. In the prepubertal period, NC cut-off points indicative overweight, in both boys and girls were 26.36 cm and 25.27 cm, respectively; the corresponding values for obesity were 26.78 cm and 25.02 cm. During puberty, the cut-off values for overweight and obesity respectively were 28.32 cm and 28.57 cm in boys and 28.70 cm and 28.82 cm in girls. CONCLUSION NC may be used as a simple and widely applicable measure for identification of overweight and obesity with reasonable accuracy in Pakistani children.
Collapse
Affiliation(s)
- Muhammad Asif
- Govt. Degree College, Qadir Pur Raan, Department of Statistics, Multan, Pakistan,* Address for Correspondence: Govt. Degree College, Qadir Pur Raan, Department of Statistics, Multan, Pakistan Phone: +923326038247 E-mail:
| | - Muhammad Aslam
- Bahauddin Zakariya University, Department of Statistics, Multan, Pakistan
| | | | - Saima Altaf
- Bahauddin Zakariya University, Department of Statistics, Multan, Pakistan
| | - Shakeel Ahmad
- Bahauddin Zakariya University, Department of Statistics, Multan, Pakistan
| |
Collapse
|
|
42
|
Al Shaikh A, Farahat F, Abaalkhail B, Kaddam I, Aseri K, Al Saleh Y, Al Qarni A, Al Shuaibi A, Tamimi W. Prevalence of Obesity and Overweight among School-Aged Children in Saudi Arabia and Its Association with Vitamin D Status. ACTA BIO-MEDICA : ATENEI PARMENSIS 2020; 91:e2020133. [PMID: 33525269 PMCID: PMC7927516 DOI: 10.23750/abm.v91i4.10266] [Citation(s) in RCA: 2] [Impact Index Per Article: 0.4] [Reference Citation Analysis] [Abstract] [Download PDF] [Figures] [Subscribe] [Scholar Register] [Received: 07/18/2020] [Accepted: 07/20/2020] [Indexed: 01/22/2023]
Abstract
BACKGROUND Childhood obesity is a significant global public health problem. Worldwide data showed an increasing trend over the years. We aimed to explore the prevalence of obesity, and its association with vitamin D status. METHODS This cross-sectional study was conducted during the period from 2016 to 2017. The study included 3613 schoolchildren aged 6-19 years in the western, central, and eastern regions in Saudi Arabia. Anthropometric data including age, sex and body mass index (BMI) was collected and the serum 25OH- vitamin D (25OHD) was measured. Age-sex standardized BMI Z-scores using the 2007 World Health Organization growth standards were applied. RESULTS Data from 3613 school-aged children (females = 51.8%), with equal percentage of participants from each region were analyzed. Prevalence of obesity and overweight was estimated at 7.1% and 14.4% respectively. An increasing trend was detected with age (p: 0.006). Obesity started to increase at the age of 10 years and continued to increase until 19 years. Most of the obese children (64.2%) had deficient vitamin D levels, compared to 33.7% of them with suboptimal levels and only 2.0% with optimal levels (p: <0.001). CONCLUSIONS This large cohort study revealed a high prevalence (21.5%) of obesity and overweight in school children aged between 6-19 years with increasing trend with age. Children with high BMI showed extremely high prevalence of VDD and VDI. These findings are alarming and point to the need for effective national interventions that include improving and encouraging access to physical activity and exposure to sunlight, educational activities for students, parents, and schoolteachers and possible enrichment of staple food with vitamin D.
Collapse
Affiliation(s)
- Adnan Al Shaikh
- King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, King Abdulaziz Medical City, Jeddah, Saudi Arabia.
| | | | | | | | | | - Yousef Al Saleh
- King Saud bin Abdulaziz University for Health Sciences - Riyadh.
| | - Ali Al Qarni
- Al Imam Abdulrahman Bin Faisal Hospital, MNGHA - Dammam.
| | | | | |
Collapse
|
|
43
|
Islam TMM, Banik PC, Barua L, Shariful Islam SM, Chowdhury S, Ahmed MSAM. Cardiovascular disease risk factors among school children of Bangladesh: a cross-sectional study. BMJ Open 2020; 10:e038077. [PMID: 33087372 PMCID: PMC7580045 DOI: 10.1136/bmjopen-2020-038077] [Citation(s) in RCA: 1] [Impact Index Per Article: 0.2] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Download PDF] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Indexed: 11/30/2022] Open
Abstract
OBJECTIVE Primarily, we assessed the distribution of cardiovascular disease (CVD) risk factors among school children living in urban and rural areas of Bangladesh. In addition to this, we sought the association between place of residence and modifiable CVD risk factors among them. DESIGN, SETTING AND PARTICIPANTS This cross-sectional study was conducted among 854 school children (aged 12-18 years) of Bangladesh. Ten public high schools (five from Dhaka and five from Sirajgonj district) were selected randomly and subjects from those were recruited conveniently. To link the family milieu of CVD risk factors, a parent of each children was also interviewed. PRIMARY AND SECONDARY OUTCOME MEASURES Distribution of CVD risk factors was measured using descriptive statistics as appropriate. Again, a saturated model of binary logistic regression was used to seek the association between place of residence and modifiable CVD risk factors. RESULTS Mean age of the school children was 14.6±1.1 years and more than half (57.6%) were boys. Overall, 4.4% were currently smoker (urban-3.5%, rural-5.2%) with a strong family history of smoking (42.2%). Similar proportion of school children were identified as overweight (total 9.8%, urban 14.7%, rural 5%) and obese (total 9.8%, urban 16.8%, rural 2.8%) with notable urban-rural difference. More than three-fourth (80%) of them were physically inactive with no urban-rural variation. Only 2.4% consumed recommended fruits and/ or vegetables (urban-3.1%, rural-1.7%). In the adjusted model, place of residence had higher odds for having several modifiable CVD risk factors: current smoking (OR: 1.807, CI 0.872 to 3.744), inadequate fruits and vegetables intake (OR: 1.094, CI 0.631 to 1.895), physical inactivity (OR: 1.082, CI 0.751 to 1.558), overweight (OR: 3.812, CI 2.245 to 6.470) and obesity (OR: 7.449, CI 3.947 to 14.057). CONCLUSIONS Both urban and rural school children of Bangladesh had poor CVD risk factors profile that demands further nation-wide large scale study to clarify the current findings more precisely.
Collapse
Affiliation(s)
- T M Manjurul Islam
- Community Medicine, Bangladesh Institute of Health Sciences, Dhaka, Dhaka District, Bangladesh
| | - Palash Chandra Banik
- Noncommunicable Diseases, Bangladesh University of Health Sciences, Dhaka, Bangladesh
| | - Lingkan Barua
- Noncommunicable Diseases, Bangladesh University of Health Sciences, Dhaka, Bangladesh
| | - Sheikh Mohammed Shariful Islam
- Exercise and Nutrition Sciences, Deakin University Faculty of Health, Burwood, Victoria, Australia
- Cardiovascular Division, The George Institute for Global Health, Sydney, New South Wales, Australia
| | - Shahanaz Chowdhury
- Community Medicine, Bangladesh Institute of Health Sciences, Dhaka, Dhaka District, Bangladesh
| | - M S A Mansur Ahmed
- Community Medicine, Bangladesh Institute of Health Sciences, Dhaka, Dhaka District, Bangladesh
| |
Collapse
|
|
44
|
Kana MA, Ahmed J, Ashiru AY, Jibrin S, Sunday AD, Shehu K, Safiyan H, Kantiyok C, Yusuf HE, Ibrahim JM, Musa S, Baduku TS, Tabari AM, Barros H, London SJ. Child Electronic Growth Monitoring System: An innovative and sustainable approach for establishing the Kaduna Infant Development (KID) Study in Nigeria. Paediatr Perinat Epidemiol 2020; 34:532-543. [PMID: 32083347 PMCID: PMC7443740 DOI: 10.1111/ppe.12641] [Citation(s) in RCA: 5] [Impact Index Per Article: 1.0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 08/13/2019] [Revised: 10/28/2019] [Accepted: 11/23/2019] [Indexed: 12/31/2022]
Abstract
BACKGROUND Developing countries bear the burden of childhood stunting but lack resources for cohort studies to develop preventive strategies. To enable future prospective studies, we designed and tested the Child Electronic Growth Monitoring System (CEGROMS) using a readily available electronic data capture platform, the Research Electronic Data Capture (REDCap). OBJECTIVES To demonstrate the feasibility of using CEGROMS for data collection for a pilot study for the Kaduna Infant Development (KID) Birth Cohort Study in Nigeria. METHODS CEGROMS consists of the data capture form for growth monitoring, a central cloud server, electronic tablets, and desktop computer. We implemented the pilot study in 2017-2019 at the Barau Dikko Teaching Hospital, Kaduna, Nigeria. Odds ratios (OR) and 95% confidence intervals (CI) were calculated for completeness of baseline data (relative to individuals with incomplete data) and completion of follow-up at different time points (relative to individuals with no follow-up visit) by the participant characteristics. Complete data were defined as date of birth, sex, and birthweight recorded at recruitment. RESULTS Among 3152 infant records in CEGROMS, 2789 (88.5%) had complete data. Of these, 1905 (68.3%) had at least one follow-up visit. The main determinants of data completeness were health facility delivery (OR 19.17, 95% CI 13.65, 26.92) and tertiary education (OR 3.54, 95% CI 2.69, 4.67). Follow-up was greater for women with tertiary education (OR 1.33, 95% CI 1.06, 1.51 for at least one visit). Maternal education is associated with completeness and follow-up (following adjustments for parity and employment). CONCLUSIONS The CEGROMS electronic data collection system enables complete and consistent data collection. The data will enable design of strategies to improve follow-up in the future implementation of the birth cohort study.
Collapse
Affiliation(s)
- Musa A. Kana
- Department of Health and Human ServicesNational Institute of Environmental Health SciencesNational Institutes of HealthResearch Triangle ParkNCUSA
- Barau Dikko Teaching HospitalKadunaNigeria
- Kaduna State UniversityKadunaNigeria
- EPIUnit‐Instituto de Saúde Pública da Universidade do PortoPortoPortugal
| | | | | | | | | | | | | | | | | | - Jimoh M. Ibrahim
- Barau Dikko Teaching HospitalKadunaNigeria
- Kaduna State UniversityKadunaNigeria
| | - Shuaibu Musa
- Barau Dikko Teaching HospitalKadunaNigeria
- Kaduna State UniversityKadunaNigeria
| | - Tokan S. Baduku
- Barau Dikko Teaching HospitalKadunaNigeria
- Kaduna State UniversityKadunaNigeria
| | | | - Henrique Barros
- EPIUnit‐Instituto de Saúde Pública da Universidade do PortoPortoPortugal
| | - Stephanie J. London
- Department of Health and Human ServicesNational Institute of Environmental Health SciencesNational Institutes of HealthResearch Triangle ParkNCUSA
| |
Collapse
|
|
45
|
Hendaus MA, El Ansari W, Magboul S, AlHalabi O, Sati M, Kamal H, Alhammadi AH. Parental perceptions of child's healthy diet: Evidence from a rapidly developing country. J Family Med Prim Care 2020; 9:4949-4955. [PMID: 33209827 PMCID: PMC7652186 DOI: 10.4103/jfmpc.jfmpc_1252_19] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/28/2019] [Revised: 03/06/2020] [Accepted: 08/03/2020] [Indexed: 11/04/2022] Open
Abstract
BACKGROUND There are no studies in Qatar or in the Middle East to investigate parental perception of healthy diet in childhood. PURPOSE To investigate parental perception of childhood healthy diet in the State of Qatar. METHODS Cross-sectional prospective study at Hamad Medical Corporation, State of Qatar. Parents of children <14 years old were invited to complete a questionnaire. RESULTS A total of 398 parents agreed to participate, while 22 parents refused (response rate 94%). About 80% of parents were between 20 and 39 years of age, and 77% were females. Around 230 (58%) parents had ≥1 housemaid to help with housework, including food preparation. Whilst 151 children (37%) fell into the overweight and obese category, only 68 parents (17%) perceived that their child was in this category. Less than half the participants (n = 179, 45%) stated that childhood weight should be monitored prior to 5 years of age, while around 35% stated the same, but for children ages 5-14 years. Most participants (n = 324, 81%) agreed that parental eating habits could influence childhood weight. In terms of food preparation at home, mothers cooked almost 50% of the times, housemaids 30%, followed by grandmothers (16.6%), and fathers (3.4%). When asked about the frequency of school meals being prepared at home, 237 parents (60%) prepared their children's lunch box only 1-2 times per week. Moreover, 63% of parents chose the quality of food based on nutritional values, while 44% and 35% chose it based on safety and taste, respectively. When queried about whether the child's pediatrician or the primary care physician counsel families regarding childhood healthy diet, 187 families (47%) had not received counseling by their children's health care providers. Most families agreed that healthy diets lead to better school performance (n = 372, 94%) and better physical activity quality (n = 379, 96%). Compared to families living in the rural areas, parents living in the capital Doha had better insights that healthy diets result in better in school performance (p = 0.032). CONCLUSION Parental perception is an important target for public health interventions. Within the current sample, families were aware of the positive impact of healthy diet on overall wellbeing. Qatar is a well-resourced country and it would be cost effective to train and professionally develop pediatricians and primary care physicians to be more proactive in tackling childhood obesity.
Collapse
Affiliation(s)
- Mohamed A. Hendaus
- Department of Pediatrics, Section of Academic General Pediatrics, Sidra Medicine, Doha, Qatar
- Department of Pediatrics, Hamad General Corporation, Doha, Qatar
- Department of Clinical Pediatrics, Weill- Cornell Medicine, Doha, Qatar
| | - Walid El Ansari
- Department of Surgery, Hamad General Corporation, Doha, Qatar
- College of Medicine, Qatar University, Doha, Qatar
- School of Health and Education, University of Skövde, Skövde, Sweden
| | - Samar Magboul
- Department of Pediatrics, Hamad General Corporation, Doha, Qatar
| | - Ola AlHalabi
- Pediatric Residency Program, Hamad General Corporation, Doha, Qatar
| | - Maram Sati
- Pediatric Residency Program, Hamad General Corporation, Doha, Qatar
| | - Hebat Kamal
- Pediatric Residency Program, Hamad General Corporation, Doha, Qatar
| | - Ahmed H. Alhammadi
- Department of Pediatrics, Section of Academic General Pediatrics, Sidra Medicine, Doha, Qatar
- Department of Pediatrics, Hamad General Corporation, Doha, Qatar
- Department of Clinical Pediatrics, Weill- Cornell Medicine, Doha, Qatar
| |
Collapse
|
|
46
|
Mansouri V, Riahi R, Khademian M, Qorbani M, Heidari-Beni M, Heshmat R, Motlagh ME, Ziaodini H, Dashti R, Taheri M, Daniali S, Kelishadi R. Factors Associated with Tendency for Weight Loss in a Representative Sample of Children and Adolescents: The CASPIAN-V Study. Int J Prev Med 2020; 11:123. [PMID: 33088451 PMCID: PMC7554429 DOI: 10.4103/ijpvm.ijpvm_358_19] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/26/2019] [Accepted: 02/20/2020] [Indexed: 11/18/2022] Open
Abstract
Background: This study aims to determine the factors affecting the tendency to lose weight (TLW) and its methods in Iranian children and adolescents. Methods: In this cross-sectional nationwide study 14800 students, aged 7–18 years, living in 30 provinces of Iran were selected via multistage cluster random sampling method. The dietary and physical activity habits and TLW as well as psychosocial health status, anxiety, self-satisfaction, and change in dietary behaviors were assessed by the global school-based student health survey (WHO-GSHS) questionnaire. Multivariate logistic regression model was used to identify factors influencing TLW. Results: Overall, 14274 students (participation rate of 99%), consisting of 51% boys and 71.4% urban residents, completed the study. Of them, 37.7% (51.4% Girls and 48.6% boys) tended to lose weight. In multivariate model, the odds for TLW was 12% higher in students aged 13–18 years than those aged 6–12 years (OR = 1.12, 95% CI: 1.02 to 1.23; P < 0.001). Students with high anxiety level were 43% more likely to have TLW (OR = 1.43, 95% CI: 1.28–1.59; P < 0.001). The odds of increasing physical activity for weight loss was 22% lower in obese than in normal weight students (OR = 0.78, 95% CI: 0.66 to 0.93; P < 0.001). Conclusions: TLW was significantly higher in girls, as well as in those with higher anxiety level. In addition to dietary change, increasing physical activity should be encouraged among children and adolescents with excess weight. Public education regarding proper lifestyle change for reaching healthy weight should be underscored.
Collapse
Affiliation(s)
- Vahid Mansouri
- Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran
| | - Roya Riahi
- Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran
| | - Majid Khademian
- Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran
| | - Mostafa Qorbani
- Department of Epidemiology, Non-communicable Diseases Research Center, Alborz University of Medical Sciences, Karaj, Iran
| | - Motahar Heidari-Beni
- Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran
| | - Ramin Heshmat
- Department of Epidemiology, Chronic Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
| | | | - Hasan Ziaodini
- Department of Health Psychology, Research Center of Education Ministry Studies, Tehran, Iran
| | - Razieh Dashti
- Bureau of Family, Population, Youth and School Health, Ministry of Health and Medical Education, Tehran, Iran
| | - Majzoubeh Taheri
- Bureau of Family, Population, Youth and School Health, Ministry of Health and Medical Education, Tehran, Iran
| | - Shahrebanoo Daniali
- Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran
| | - Roya Kelishadi
- Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran
| |
Collapse
|
|
47
|
Moeng-Mahlangu LT, Monyeki MA, Reilly JJ, Mchiza ZJ, Moleah T, Loechl CU, Kruger HS. Level of agreement between objectively determined body composition and perceived body image in 6- to 8-year-old South African children: The Body Composition-Isotope Technique study. PLoS One 2020; 15:e0237399. [PMID: 32777810 PMCID: PMC7417193 DOI: 10.1371/journal.pone.0237399] [Citation(s) in RCA: 3] [Impact Index Per Article: 0.6] [Reference Citation Analysis] [Abstract] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/25/2020] [Accepted: 07/26/2020] [Indexed: 01/05/2023] Open
Abstract
To assess the level of agreement between body size self-perception and actual body size determined by body mass index (BMI) z-score and body fatness measured by the deuterium dilution method (DDM) in South African children aged 6–8 years. A cross-sectional sample of 202 children (83 boys and 119 girls) aged 6–8 years from the Body Composition–Isotope Technique study (BC–IT) was taken. Subjective measures of body image (silhouettes) were compared with the objective measures of BMI z-score and body fatness measured by the DDM. The World Health Organization BMI z-scores were used to classify the children as underweight, normal, overweight, or obese. DDM-measured fatness was classified based on the McCarthy centile curves set at 2nd, 85th and 95th in conjunction with fatness cut-off points of 25% in boys and 30% in girls. Data were analyzed using SPSS v26. Of 202 children, 32.2%, 55.1%, 8.8%, and 2.4% perceived their body size as underweight, normal, overweight, and obese, respectively. Based on BMI z-score, 18.8%, 72.8%, 6.9%, and 1.5% were classified as underweight, normal, overweight, and obese, respectively. Body fatness measurement showed that 2.5%, 48.0%, 21.8%, and 29.7% were underweight, normal weight, overweight, and obese, respectively. The application of silhouettes and BMI z-scores resulted in either overestimation or underestimation of own body size. Overall, the levels of agreements (kappa, κ) between body size perception, body fatness, and BMI for age respectively, were small (κ = 0.083, p = 0.053 and κ = 0.154, p<0.001). Level of agreement between body size perception, body fatness, and BMI z-score was poor. The use of silhouettes made children either overestimate their own body size while being underweight or underestimate their own body size while being overweight or obese. Given the potential health implications associated with misclassification of body size during childhood, correct self-assessment of body size is important, and may be key to the adoption of weight control strategies directed at curbing the escalating obesity epidemic in the country. Scalable measures to allow for more accurate self-assessment are urgently needed–one approach is behavior change communication at all levels.
Collapse
Affiliation(s)
- Lynn T Moeng-Mahlangu
- Physical Activity, Sport and Recreation Research Focus Area, Faculty of Health Sciences, North-West University, Potchefstroom, South Africa
| | - Makama A Monyeki
- Physical Activity, Sport and Recreation Research Focus Area, Faculty of Health Sciences, North-West University, Potchefstroom, South Africa
| | - John J Reilly
- Physical Activity for Health Group, School of Psychological Sciences and Health, University of Strathclyde, Glasgow, United Kingdom
| | - Zandile J Mchiza
- School of Public Health (SoPH), University of the Western Cape, Cape Town, South Africa
| | - Thabisile Moleah
- International Atomic Energy Agency (IAEA), Division of Human Health, Vienna International Centre, Vienna, Austria
| | - Cornelia U Loechl
- International Atomic Energy Agency (IAEA), Division of Human Health, Vienna International Centre, Vienna, Austria
| | - Herculina S Kruger
- Centre of Excellence for Nutrition, North-West University, Potchefstroom, South Africa
| |
Collapse
|
|
48
|
Goodarzi G, Keshavarz SA, Hosseini-Esfahani F, Ataie-Jafari A. Associations between Dietary Diversity Scores and Obesity Phenotypes in Women. NUTRITION AND FOOD SCIENCES RESEARCH 2020. [DOI: 10.29252/nfsr.7.4.13] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 10/31/2022] Open
|
|
49
|
Lee J. Influences of Cardiovascular Fitness and Body Fatness on the Risk of Metabolic Syndrome: A Systematic Review and Meta-Analysis. Am J Health Promot 2020; 34:796-805. [PMID: 32431155 DOI: 10.1177/0890117120925347] [Citation(s) in RCA: 10] [Impact Index Per Article: 2.0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 12/31/2022]
Abstract
OBJECTIVE The purpose of this meta-analysis was to investigate the associations between combined cardiovascular fitness, obesity, and the risk of metabolic syndrome. DATA SOURCES The MEDLINE and EMBASE databases were used to select relevant studies that included the relative risk (RRs) of metabolic syndrome based on the combined effects of cardiovascular fitness and obesity from January 1990 to July 2019. STUDY INCLUSION AND EXCLUSION CRITERIA The inclusion criteria were providing the RRs for the associations between combined cardiovascular fitness and obesity and the risk of metabolic syndrome. The exclusion criteria were review studies, duplicated studies, and no RRs reported for those associations. DATA EXTRACTION All selected studies categorized levels of cardiovascular fitness (high cardiovascular fitness vs low cardiovascular fitness) and obesity (normal vs obesity) and directly extracted the RRs for the risk of metabolic syndrome from these data. All selected studies were cross-sectional studies. DATA SYNTHESIS All RRs and 95% CIs from the selected studies were computed to find the associations between combined cardiovascular fitness and obesity and the risk of metabolic syndrome. RESULTS A total of 8 studies were selected for this meta-analysis. Low cardiovascular fitness was associated with 3. Fifty-nine times increased metabolic syndrome risk regardless of obesity (3.59, 95% CI: 3.07-4.20; P = .00). And obesity was associated with 1.62 times increased metabolic syndrome risk regardless of cardiovascular fitness level (1.62, 95% CI: 1.32-1.98; P = .00). Lastly, the risk of metabolic syndrome decreased by 77% with high cardiovascular fitness regardless of obesity (0.23, 95% CI: 0.12-0.43; P = .00). CONCLUSIONS The combined effects of cardiovascular fitness and obesity are important factors when determining metabolic syndrome risk. The minimum level of cardiovascular fitness is 8.39 metabolic equivalent (METs) for adults to lower the risk of metabolic syndrome. Enhanced cardiovascular fitness and maintaining normal weight should be recommended for individuals to reduce the risk of metabolic syndrome.
Collapse
Affiliation(s)
- Junga Lee
- Assistant Professor, Sports Medicine and Science, 26723KyungHee University, Gyeonggi-do, Republic of Korea
| |
Collapse
|
|
50
|
Alhusaini AA, Buragadda S, Melam G. Associations among Body Mass Index, sedentary behavior, physical activity, and academic performance in schoolchildren. J Sports Med Phys Fitness 2020; 60:1551-1557. [PMID: 32343080 DOI: 10.23736/s0022-4707.20.10482-1] [Citation(s) in RCA: 3] [Impact Index Per Article: 0.6] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 11/08/2022]
Abstract
BACKGROUND Physical inactivity and sedentary behavior are common among middle and high school grade children. This study aimed to determine the relationship among Body Mass Index (BMI), sedentary behavior, physical activity (PA), and overall academic performance of students. METHODS This is a cross sectional study; 357 students of mean age 12.65±1.68 years were enrolled. PA was subjectively assessed using the Physical Activity Questionnaire for Children (PAQ-C) and Godin Leisure-Time Exercise Questionnaire (GLTEQ). Sedentary behavior was assessed as hours spent on watching television, playing video games, computer use, and homework. Grade point average (GPA) was calculated to determine their overall academic performance. Participants were divided into two groups based on their GPA. Independent t-test was used to analyze BMI, sedentary time, and PA between the groups. Correlation analysis was performed to determine the associations among BMI, sedentary time, physical activity, and academic grades. RESULTS There was no significant difference in BMI and the level of PA between the two groups. However, significant differences were observed in sedentary time (ST) spent watching television (P=0.04), total screen time (P=0.02), and total ST (P=0.002). There were weak negative correlations among BMI (r=-0.14, P<0.05), total screen time (r=-0.12, P<0.05), and academic scores; however, there was no association with any PA measures. CONCLUSIONS A weak correlation was noted between BMI and sedentary characteristics, with respect to academic performance. As academic performance is negatively associated with body mass index and screen time, public health interventions are needed to reduce their time spent on leisure time sedentary activity, watching television, and computer use.
Collapse
Affiliation(s)
- Adel A Alhusaini
- Department of Rehabilitation Health Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia
| | - Syamala Buragadda
- Department of Rehabilitation Health Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia -
| | - Ganeswararao Melam
- Department of Rehabilitation Health Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia
| |
Collapse
|