Protective effect of boric acid on kidney tissue and oxidative stress after testicular torsion/detorsion in male rats

Table 1 Antioxidant/oxidant status parameters, mean ± SE

	Group control (n = 6)	Group BA (n = 6)	Group I/R (n = 6)	Group BA-I/R (n = 6)	aP value
GST (IU/mg protein)	1.90 ± 0.44	2.04 ± 0.08	1.45 ± 0.13	1.62 ± 0.18	0.111
CAT (IU/mg protein)	4192 ± 276	3797 ± 558	3610 ± 432	3810 ± 438	0.637
PON-1 (IU/mg protein)	2.74 ± 0.24	2.50 ± 0.13	1.69 ± 0.13b,c	2.25 ± 0.17d	0.010
MDA (nmol/ mg protein)	4.78 ± 0.30	5.17 ± 0.32	7.98 ± 0.60b,c	5.90 ± 0.59d	0.002

^aP < 0.05 indicates significance level with Kruskal-Wallis test.

^bP < 0.05 vs group control.

^cP < 0.05 vs group boric acid.

^dP < 0.05 vs group ischemia/reperfusion.

GST: Glutathione S-transferase; CAT: Catalase; PON-1: Paraoxonase-1; MDA: Malondialdehyde; BA: Boric acid; I/R: Ischemia/reperfusion.

Table 2 Kidney tissue histopathological findings, mean ± SE

	Group control (n = 6)	Group BA (n = 6)	Group I/R (n = 6)	Group BA-I/R (n = 6)	aP value
GV	0.17 ± 0.17	0.33 ± 0.21	1.33 ± 0.21b,c	1.00 ± 0.26b	0.008
TD	0.50 ± 0.22	0.33 ± 0.21	1.83 ± 0.17b,c	0.83 ± 0.31d	0.007
VVH	0.33 ± 0.21	0.33 ± 0.21	1.33 ± 0.21b,c	0.67 ± 0.21d	0.025
TCDN	0.00 ± 0.00	0.33 ± 0.21	1.00 ± 0.00b,c	0.50 ± 0.21	0.005
BSD	0.33 ± 0.21	0.50 ± 0.22	1.00 ± 0.26	0.50 ± 0.34	0.295
THC	0.33 ± 0.21	0.50 ± 0.22	1.00 ± 0.00	0.67 ± 0.21	0.113
LI	0.50 ± 0.22	0.50 ± 0.22	1.17 ± 0.17	0.67 ± 0.21	0.133
TCS	0.33 ± 0.21	0.50 ± 0.22	0.83 ± 0.17	0.67 ± 0.21	0.335

^aP < 0.05 indicates significance level with Kruskal-Wallis test.

^bP < 0.05 vs group control.

^cP < 0.05 vs group boric acid.

^dP < 0.05 vs group ischemia/reperfusion.

BA: Boric acid; I/R: Ischemia/reperfusion; GV: Glomerular vacuolization; TD: Tubular dilatation; VVH: Vascular vacuolization and hypertrophy; TCDN: Tubular cell degeneration and necrosis; BSD: Bowman space dilatation; THC: Tubular hyaline casts; LI: Lymphocyte infiltration; TCS: Tubular cell shedding.