Renal tubular acidosis complication of non-steroidal anti-inflammatory drugs induced interstitial nephritis and its complete resolution with steroids: A case report

Figure 1 Light microscopic picture. A: Showing active interstitial inflammation with lymphocytes, plasma cells, rare neutrophils, and eosinophils (arrows); B: Showing mild to moderate tubulitis (blue arrows) and tubular atrophy with narrowed lumens in shrunken tubules and cuboidal epithelial cells (black arrows); C: Showing moderate interstitial fibrosis and tubular atrophy (pale blue arrows) involving approximately 40% of the biopsied cortex. Also has multifocal interstitial infiltrate (orange arrows).

Figure 2 Serum potassium and bicarbonate levels on admission and throughout the course, along with the supplementation dosage. A: Clinical course of serum potassium along with the dose of potassium chloride supplementation; B: Clinical course of serum bicarbonate along with the dose of sodium bicarbonate supplementation.