Endocrine disorders linked to chronic kidney disease: Mechanisms and clinical implications

doi:10.5527/wjn.v15.i1.113875

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Mar 25, 2026 (publication date) through Mar 14, 2026

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World Journal of Nephrology

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2220-6124

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Nephrol. Mar 25, 2026; 15(1): 113875
Published online Mar 25, 2026. doi: 10.5527/wjn.v15.i1.113875

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Figure 1 Hormone axes involved in chronic kidney disease. Overview of the mechanisms underlying the main endocrine pathways affected in chronic kidney disease. CKD: Chronic kidney disease; PO₄^3-: Phosphate; FGF-23: Fibroblast growth factor 23; PTH: Parathyroid hormone; sHPT: Secondary hyperparathyroidism; EPO: Erythropoietin; ROS: Reactive oxygen species; IL-6: Interleukin 6; TNF-α: Tumor necrosis factor alpha; Ca: Calcium; TSH: Thyroid-stimulating hormone; TRH: Thyrotropin-releasing hormone; T3: Triiodothyronine; T4: Thyroxine; GnRH: Gonadotropin-releasing hormone; FSH: Follicle-stimulating hormone; LH: Luteinizing hormone; TT: Total testosterone; FT: Free testosterone.

Citation: Concepción-Zavaleta MJ, Fuentes-Mendoza JM, López-Ramírez EP, Martínez-García JA, Concepción-Urteaga LA, Paz-Ibarra J. Endocrine disorders linked to chronic kidney disease: Mechanisms and clinical implications. World J Nephrol 2026; 15(1): 113875
URL: https://www.wjgnet.com/2220-6124/full/v15/i1/113875.htm
DOI: https://dx.doi.org/10.5527/wjn.v15.i1.113875