©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Nephrol. Nov 6, 2015; 4(5): 487-491
Published online Nov 6, 2015. doi: 10.5527/wjn.v4.i5.487
Published online Nov 6, 2015. doi: 10.5527/wjn.v4.i5.487
Biomarkers in kidney transplantation: From bench to bedside
Natavudh Townamchai, Somchai Eiam-Ong, Division of Nephrology, Department of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok 10330, Thailand
Natavudh Townamchai, Center of Excellence in Solid Organ Transplantation, King Chulalongkorn Memorial Hospital, Bangkok 10330, Thailand
Author contributions: Townamchai N contributed to review the articles and write the manuscript; Eiam-Ong S contributed to design the manuscript topics and write the manuscript.
Conflict-of-interest statement: Authors declare no conflict of interest.
Correspondence to: Somchai Eiam-Ong, MD, Professor, Division of Nephrology, Department of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Pathum Wan, Bangkok10330, Thailand. somchai80754@hotmail.com
Telephone: +662-256-4251
Received: May 28, 2015
Peer-review started: May 31, 2015
First decision: July 10, 2015
Revised: July 24, 2015
Accepted: September 10, 2015
Article in press: September 16, 2015
Published online: November 6, 2015
Processing time: 168 Days and 2.4 Hours
Peer-review started: May 31, 2015
First decision: July 10, 2015
Revised: July 24, 2015
Accepted: September 10, 2015
Article in press: September 16, 2015
Published online: November 6, 2015
Processing time: 168 Days and 2.4 Hours
Core Tip
Core tip: There are many studies about roles and benefits of biomarkers in nephrology, including transplantation. Only some of them reach the clinical level with strong evidence support. Biomarkers can guide immunosuppressive adjustment, provide prognostic value, and guide early detect of allograft injury, particularly from allograft rejection. We summarized the potential biomarkers for kidney transplantation monitoring, including clinical implication, strength and weakness of each of them.