©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Nephrol. May 6, 2015; 4(2): 277-286
Published online May 6, 2015. doi: 10.5527/wjn.v4.i2.277
Published online May 6, 2015. doi: 10.5527/wjn.v4.i2.277
Management of hepatorenal syndrome
Halit Ziya Dundar, Tuncay Yılmazlar, Department of General Surgery, Faculty of Medicine, Uludag University, Gorukle, 16285 Bursa, Turkey
Author contributions: Both authors contributed to this manuscript.
Conflict-of-interest: The authors declare no conflicts of interest regarding this manuscript.
Correspondence to: Halit Ziya Dundar, MD, Department of General Surgery, Faculty of Medicine, Uludag University, Gorukle, 16285 Bursa, Turkey. hzdundar@hotmail.com
Telephone: +90-224-2952040 Fax: +90-224-4428398
Received: June 29, 2014
Peer-review started: June 29, 2014
First decision: August 14, 2014
Revised: December 29, 2014
Accepted: January 30, 2015
Article in press: February 2, 2015
Published online: May 6, 2015
Processing time: 313 Days and 12.2 Hours
Peer-review started: June 29, 2014
First decision: August 14, 2014
Revised: December 29, 2014
Accepted: January 30, 2015
Article in press: February 2, 2015
Published online: May 6, 2015
Processing time: 313 Days and 12.2 Hours
Core Tip
Core tip: Hepatorenal syndrome (HRS) is a severe complication of chronic liver diseases and is usually associated with a poor prognosis. It is not a renal disease but a renal dysfunction that develops as a result of a systemic condition associated with liver failure. To prevent HRS by taking some preventive measures is possible and although the definitive treatment is liver transplantation, a rapid diagnosis and prompt initiation of the treatment leads to an important improvement in the prognosis. In this review, we cover the physiopathology, diagnosis and treatment options of HRS.