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Renal diseases and blood pressure dysregulation in acute care: Pathophysiology, clinical patterns
Yu-Jang Su, Division of Toxicology, Department of Emergency Medicine, MacKay Memorial Hospital, Taipei 10449, Taiwan
Yu-Jang Su, Department of Nursing, Yuanpei University of Medical Technology, Hsinchu 300, Taiwan
Yu-Jang Su, School of Medicine, College of Medicine, Mackay Medical University, New Taipei City 252005, Taiwan
Yu-Jang Su, Department of Nursing, MacKay Junior College of Medicine, Nursing and Management, New Taipei 252, Taiwan
Author contributions: Su YJ was responsible for program investigator, writing draft, revision, and corresponding.
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Corresponding author: Yu-Jang Su, MD, Associate Professor, Division of Toxicology, De
Received: March 27, 2026
Revised: April 22, 2026
Accepted: June 11, 2026
Published online: September 25, 2026
Processing time: 139 Days and 10.6 Hours
Revised: April 22, 2026
Accepted: June 11, 2026
Published online: September 25, 2026
Processing time: 139 Days and 10.6 Hours
Core Tip
Core Tip: Blood pressure abnormalities in renal diseases present distinct yet mechanistically predictable patterns in the emergency department. Hypotension often reflects hypoperfusion, sepsis, or trauma, while hypertension is commonly driven by renin-angiotensin-aldosterone system activation, volume overload, or renal ischemia. Recognizing these characteristic hemodynamic profiles enables rapid diagnosis, risk stratification, and targeted management. Integrating blood pressure patterns with clinical context provides a practical and efficient framework for evaluating various renal conditions in acute care settings.