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World J Nephrol. Jun 25, 2026; 15(2): 117833
Published online Jun 25, 2026. doi: 10.5527/wjn.v15.i2.117833
Published online Jun 25, 2026. doi: 10.5527/wjn.v15.i2.117833
Risk factors of mortality in patients with acute kidney injury: Retrospective cohort study with longitudinal follow-up
Nouha Ben Mahmoud, Mouna Hamouda, Meriem Ben Salem, Manel Ben Salah, Faten Ghabi, Khouloud Hafi, Sirine Bchir, Ahmed Letaief, Habib Skhiri, Department of Nephrology, Dialysis and Renal Transplantation, Fattouma Bourguiba University Hospital, Monastir 5001, Tunisia
Nouha Ben Mahmoud, Mouna Hamouda, Meriem Ben Salem, Manel Ben Salah, Faten Ghabi, Khouloud Hafi, Sirine Bchir, Ahmed Letaief, Habib Skhiri, Faculty of Medicine, University of Monastir, Monastir 5001, Tunisia
Nouha Ben Mahmoud, Meriem Ben Salem, Manel Ben Salah, Laboratory of Research on Biologically Compatible Substances, LR01ES17, Faculty of Dental Medicine, Monastir 5001, Tunisia
Co-first authors: Nouha Ben Mahmoud and Mouna Hamouda.
Author contributions: Ben Mahmoud N and Hamouda M contributed equally to this article and are the co-first authors of this manuscript; Ben Salem M, Ben Salah M, Ghabi F, Hafi K, Bchir S, Letaief A, and Skhiri H contributed equally to this manuscript and share last authorship; All authors thoroughly reviewed and approved the final manuscript.
Institutional review board statement: This study was approved by the Medical Ethics Committee of University of Monastir and because it was a retrospective study the committee didn’t provide us a certificate.
Informed consent statement: Signed informed consent was obtained from all participants contacted after discharge.
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Data sharing statement: No data available.
Corresponding author: Nouha Ben Mahmoud, Assistant Professor, Department of Nephrology, Dialysis and Renal Transplantation, Fattouma Bourguiba University Hospital, Farhat Hached Avenue 5001 Monastir, Monastir 5002, Tunisia. bmahmoudnouha@gmail.com
Received: December 17, 2025
Revised: January 9, 2026
Accepted: February 25, 2026
Published online: June 25, 2026
Processing time: 180 Days and 19.3 Hours
Revised: January 9, 2026
Accepted: February 25, 2026
Published online: June 25, 2026
Processing time: 180 Days and 19.3 Hours
Core Tip
Core Tip: An article with a longitudinal follow-up study was conducted in a North African country for which data are lacking in the literature, with a long follow-up period of up to 18 years. We identified some mortality risk factors such as hypertension, age over 65 years, diabetes, vascular disease, high Charlson comorbidity index, potassium levels above 5.5 mmol/L, pre-renal acute kidney injury, and the short-term development of chronic kidney disease.