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World J Nephrol. Dec 25, 2025; 14(4): 110896
Published online Dec 25, 2025. doi: 10.5527/wjn.v14.i4.110896
Non-traditional cardiovascular risk factors after kidney transplantation
Amer Ashaab Belal, Alfonso H Santos Jr, Amir Kazory
Amer Ashaab Belal, Alfonso H Santos Jr, Amir Kazory, Division of Nephrology, Hypertension, and Renal Transplantation, University of Florida College of Medicine, Gainesville, FL 32610, United States
Author contributions: Belal AA contributed to conception and design of the work, leading the writing of the original draft, literature review, critical revision and editing, and approval of the final version of the manuscript; Santos Jr AH contributed to the literature review, writing, revision and approval of the final version of the manuscript; Kazory A contributed to the critical revision, editing, and approval of the final version of the manuscript.
Conflict-of-interest statement: All the authors declare that they have no conflict of interest.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Amer Ashaab Belal, MD, Assistant Professor, FASN, Division of Nephrology, Hypertension, and Renal Transplantation, University of Florida College of Medicine, 1600 SW Archer Road, Room CG-98, Communicore Building, Gainesville, FL 32610, United States. abelal@ufl.edu
Received: June 18, 2025
Revised: July 7, 2025
Accepted: October 11, 2025
Published online: December 25, 2025
Processing time: 188 Days and 12.6 Hours
Core Tip

Core Tip: Kidney transplantation offers improved quality of life and survival advantages in addition to a reduced cardiovascular disease risk overall compared to remaining on long-term dialysis. However, kidney transplant recipients continue to experience a higher risk of adverse cardiovascular disease outcomes compared to the general population, with many of these risk factors worsened by and specific to their transplant.