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Systematic Reviews
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World J Nephrol. Sep 25, 2025; 14(3): 105288
Published online Sep 25, 2025. doi: 10.5527/wjn.v14.i3.105288
Safety, feasibility, and efficacy of surgical intervention for Urolithiasis in patients with chronic kidney disease: A systematic review
Shiv C Navriya, Om K Yadav, Ankit Shettar, Mahendra Singh, Jaydeep Jain, Shashank Kumar, Deepak P Bhirud, Gautam R Choudhary, Arjun S Sandhu
Shiv C Navriya, Om K Yadav, Ankit Shettar, Mahendra Singh, Jaydeep Jain, Shashank Kumar, Deepak P Bhirud, Gautam R Choudhary, Arjun S Sandhu, Department of Urology, All India Institute of Medical Sciences, Jodhpur 342008, Rājasthān, India
Co-first authors: Shiv C Navriya and Om K Yadav.
Co-corresponding authors: Ankit Shettar and Mahendra Singh.
Author contributions: Navriya SC and Singh M contributed to idea on review; Shettar A, Kumar S, Jain J and Yadav OK contributed to review of literature and manuscript writing; Bhirud DP, Choudhary GR Sandhu AS contributed to revision of draft.
Conflict-of-interest statement: No conflict of interest to disclose.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Mahendra Singh, Associate Professor, Department of Urology, All India Institute of Medical Sciences, Basni industrial area, Jodhpur 342008, Rājasthān, India. drmahi1118@gmail.com
Received: January 18, 2025
Revised: March 26, 2025
Accepted: June 9, 2025
Published online: September 25, 2025
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Core Tip

Core Tip: This systematic review evaluates the safety, feasibility, and efficacy of surgical interventions for urolithiasis in patients with chronic kidney disease (CKD). Key findings highlight that while techniques such as percutaneous nephrolithotomy, ureteroscopy, and shock wave lithotripsy achieve technical success rates, they are associated with significant risks, including bleeding, infection, and acute kidney injury, especially in advanced CKD. Modifications to standard surgical methods are often required to address patient-specific factors. Stone-free rates vary across interventions, and long-term renal outcomes remain inconsistent, emphasizing the need for individualized treatment plans and further high-quality research to guide optimal management of patients with CKD.