He L. Letter to the Editor: Early identification of mortality risk in emergency patients with chronic kidney disease - insights from India with global implications. World J Nephrol 2026; 15(2): 114823 [DOI: 10.5527/wjn.v15.i2.114823]
Corresponding Author of This Article
Liang He, Department of Urology, Jilin University First Hospital, No. 1 Xinmin Street, Changchun 130000, Jilin Province, China. lianghe9278@jlu.edu.cn
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Urology & Nephrology
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letter
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He L. Letter to the Editor: Early identification of mortality risk in emergency patients with chronic kidney disease - insights from India with global implications. World J Nephrol 2026; 15(2): 114823 [DOI: 10.5527/wjn.v15.i2.114823]
World J Nephrol. Jun 25, 2026; 15(2): 114823 Published online Jun 25, 2026. doi: 10.5527/wjn.v15.i2.114823
Letter to the Editor: Early identification of mortality risk in emergency patients with chronic kidney disease - insights from India with global implications
Liang He
Liang He, Department of Urology, Jilin University First Hospital, Changchun 130000, Jilin Province, China
Author contributions: He L contributed to the conception and writing of the manuscript.
Conflict-of-interest statement: Dr. He has nothing to disclose.
Corresponding author: Liang He, Department of Urology, Jilin University First Hospital, No. 1 Xinmin Street, Changchun 130000, Jilin Province, China. lianghe9278@jlu.edu.cn
Received: September 29, 2025 Revised: November 13, 2025 Accepted: January 8, 2026 Published online: June 25, 2026 Processing time: 257 Days and 15.3 Hours
Abstract
Chronic kidney disease (CKD), has emerged as a global public health challenge, with persistently high mortality rates among patients presenting to the emergency department, particularly in resource-limited low- and middle-income countries. I read with great interest the recent article published in the World Journal of Nephrology by Prabhahar et al, conducting a retrospective analysis from a large tertiary referral center in northern India and identifying three independent predictors of in-hospital mortality at emergency department admission: Decreased Glasgow coma scale score, hyperglycemia, and low serum albumin. The significance of this study lies in underscoring the prognostic value of dynamic physiological parameters, which appear to more accurately reflect acute illness severity than traditional measures such as CKD stage or long-term comorbidity indices. This editorial highlight three key implications for clinical practice: First, it is crucial for emergency and nephrology teams to recognize high-risk patients early; Second, implementing standardized risk stratification within the emergency guideline is essential; Third, future multicenter prospective studies could help validate these predictive markers across diverse populations. In conclusion, early identification and systematic risk assessment of high-risk CKD patients in the emergency department are important steps toward improving in-hospital outcomes.
Core Tip: Three valuable prognostic markers: Low Glasgow coma scale, hyperglycemia, and hypoalbuminemia-can effectively predict mortality in chronic kidney disease patients presenting to the emergency department, supporting early risk stratification in resource-limited settings.
