©The Author(s) 2015.
World J Virology. Nov 12, 2015; 4(4): 313-322
Published online Nov 12, 2015. doi: 10.5501/wjv.v4.i4.313
Published online Nov 12, 2015. doi: 10.5501/wjv.v4.i4.313
Table 1 Similarities and differences between hepatitis delta virus and plant viroids
| HDV (1700 nt) | Pospiviroidae (200-400 nt) | Avsunviroidae (200-400 nt) |
| Circular ssRNA | Circular ssRNA | Circular ssRNA |
| Extensive intramolecular base pairing | Extensive intramolecular base pairing | Extensive intramolecular base pairing |
| A DNA-directed RNA polymerase makes both plus and minus strands | A DNA-directed RNA polymerase makes both plus and minus strands | A DNA-directed RNA polymerase makes both plus and minus strands |
| Encodes for protein | No proteins encoded | No proteins encoded |
| Virion maturation depends on a helper virus | Replication does not depend on the presence of a helper virus | Replication does not depend on the presence of a helper virus |
| Symmetric rolling circle RNA replication | Asymmetric rolling circle RNA replication | Symmetric rolling circle RNA replication |
| Replicates in the nucleus | Replicates in the nucleus | Replicates in chloroplasts |
| Ribozyme activity | No ribozyme activity | Ribozyme activity |
- Citation: Cunha C, Tavanez JP, Gudima S. Hepatitis delta virus: A fascinating and neglected pathogen. World J Virology 2015; 4(4): 313-322
- URL: https://www.wjgnet.com/2220-3249/full/v4/i4/313.htm
- DOI: https://dx.doi.org/10.5501/wjv.v4.i4.313