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Basic Study
©The Author(s) 2023.
World J Virol. Jun 25, 2023; 12(3): 209-220
Published online Jun 25, 2023. doi: 10.5501/wjv.v12.i3.209
Table 1 Comparison of hepatitis B virus integration breakpoints among reference genomes

GRCh38
T2T-CHM13
Original
Tumor
Number of breakpoints24392487 3486
Number of samples357355 328
Non-tumor
Number of breakpoints27592874739
Number of samples288288160
Table 2 Comparison of frequent integration breakpoints in the samples
Gene
GRCh38
Original
Breakpoints (n)
Samples (n)
Breakpoints (n)
Samples (n)
Tumor
TERT15010516095
KMT2B56335530
DDX11L1003623
CCNA2127148
CCNE1139147
Non-tumor
FN197561917
TERT121083
IQGAP27511
KMT2B7453
Table 3 Hepatitis B virus integration breakpoints in mitochondrial DNA
Sample
Tumor/Non-tumor
Chromosome
Position
HBV
Quality score
SRR3104746NTchrM536712476933.33
SRR3105143NTchrM5682151311817.58
SRR3105012TchrM82201122080.04
SRR3104491NTchrM8524248233322.16
SRR3105095NTchrM86944714209.06
SRR3105101NTchrM1107915592937.33
SRR3105143NTchrM11079155914876.83
SRR3105001NTchrM11104159045538.21
SRR3105149NTchrM11104159016156.63
SRR3105251NTchrM1110415902276.31
SRR3105293NTchrM11104159024562.69
SRR3104643TchrM11104159013683.16
SRR3105172TchrM1112616212610.44
SRR3105251NTchrM1113016256793.43
SRR3104939NTchrM11139172930830.54
SRR3105149NTchrM124533232345.03
SRR3104636NTchrM12735138126840.64
SRR3105083NTchrM1327317554230.85
SRR3104696NTchrM134333632963.36
SRR3104643TchrM1396428092222.86
SRR3104823NTchrM1405210171788.18
SRR3105049NTchrM14892176821102.87
SRR3104982TchrM15679176832371.78
SRR3105185NTchrM1631917882013.53


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