| For: | Dominari A, Hathaway III D, Pandav K, Matos W, Biswas S, Reddy G, Thevuthasan S, Khan MA, Mathew A, Makkar SS, Zaidi M, Maher M, Beas R, Castaneda V, Paul T, Halpern J, Baralt D. Thymosin alpha 1: A comprehensive review of the literature. World J Virol 2020; 9(5): 67-78 [PMID: 33362999 DOI: 10.5501/wjv.v9.i5.67] |
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| URL: | https://www.wjgnet.com/2220-3249/full/v9/i5/67.htm |
| Number | Citing Articles |
| 1 |
Fadi Shehadeh, Gregorio Benitez, Evangelia K Mylona, Quynh-Lam Tran, Maria Tsikala-Vafea, Eleftheria Atalla, Matthew Kaczynski, Eleftherios Mylonakis. A Pilot Trial of Thymalfasin (Thymosin-α-1) to Treat Hospitalized Patients With Hypoxemia and Lymphocytopenia Due to Coronavirus Disease 2019 Infection. The Journal of Infectious Diseases 2023; 227(2) doi: 10.1093/infdis/jiac362
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| 2 |
Association between pretreatment lymphocyte count and efficacy of immune-enhancing therapy in acute necrotising pancreatitis: a post-hoc analysis of the multicentre, randomised, placebo-controlled TRACE trial. eClinicalMedicine 2023; 58 doi: 10.1016/j.eclinm.2023.101915
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| 3 |
Yatin Mehta, Subhal B Dixit, Kapil Zirpe, Randhir Sud, Palepu B Gopal, Parvaiz A Koul, Vijay K Mishra, Abdul S Ansari, Vijay S Chamle. Therapeutic Approaches in Modulating the Inflammatory and Immunological Response in Patients With Sepsis, Acute Respiratory Distress Syndrome, and Pancreatitis: An Expert Opinion Review. Cureus 2021; doi: 10.7759/cureus.18393
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| 4 |
Lyailya Baktybayeva, Altynay B. Kaldybayeva, Anastassiya Sokolenko, Bagila Tursynova, Assel Yu. Ten, Guldana Daulet, Erkebulan Svambayev, Mario Thevis, Valentina K. Yu, Khaidar S. Tassibekov. Targeting Leukopoiesis: Pharmacological and Biotechnological Strategies for the Treatment of Leukopenia. Biomedicines 2026; 14(3) doi: 10.3390/biomedicines14030624
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| 5 |
Jyotsana Singh, Sarat Kumar Kottarath, Farhad Bano, Mohd Farhan, Amit Kumar Tripathi, Yogesh Srivastava. Clinical Applications of Biomolecules in Disease Diagnosis. 2024; doi: 10.1007/978-981-97-4723-8_11
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| 6 |
Nicholas Salvo, Angel M. Charles, Alicia M. Mohr. The Intersection of Trauma and Immunity: Immune Dysfunction Following Hemorrhage. Biomedicines 2024; 12(12) doi: 10.3390/biomedicines12122889
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| 7 |
Valéria Bumiller-Bini Hoch, Ana Flávia Kohler, Danillo G. Augusto, Sara Cristina Lobo-Alves, Danielle Malheiros, Gabriel Adelman Cipolla, Angelica Beate Winter Boldt, Karin Braun-Prado, Michael Wittig, Andre Franke, Claudia Pföhler, Margitta Worm, Nina van Beek, Matthias Goebeler, Miklós Sárdy, Saleh Ibrahim, Hauke Busch, Enno Schmidt, Jennifer Elisabeth Hundt, Patrícia Savio de Araujo-Souza, Maria Luiza Petzl-Erler. Genetic Associations and Differential mRNA Expression Levels of Host Genes Suggest a Viral Trigger for Endemic Pemphigus Foliaceus. Viruses 2022; 14(5) doi: 10.3390/v14050879
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| 8 |
Muhammad Shahbaz Aslam, Syed Zohaib Javaid Zaidi, Rabail Hassan Toor, Iram Gull, Muhammad Mudassir Iqbal, Zaigham Abbas, Imran Tipu, Aftab Ahmed, Muhammad Amin Athar, Christian Harito, Sammer-ul Hassan. Interferon α2–Thymosin α1 Fusion Protein (IFNα2–Tα1): A Genetically Engineered Fusion Protein with Enhanced Anticancer and Antiviral Effect. Materials 2021; 14(12) doi: 10.3390/ma14123318
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| 9 |
Hanzhou Li, Shan lin, Yuming Wang, Yuexuan Shi, Xixing Fang, Jida Wang, Huantian Cui, Yuhong Bian, Xin Qi. Immunosenescence: A new direction in anti-aging research. International Immunopharmacology 2024; 141 doi: 10.1016/j.intimp.2024.112900
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| 10 |
Jérémy C. Santamaria, Magali Irla. Age-related thymic involution: Mechanistic insights and rejuvenating approaches to restore immune function. Science Advances 2026; 12(7) doi: 10.1126/sciadv.aeb2970
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| 11 |
Ángel Bulnes-Ramos, María Mar Pozo-Balado, Israel Olivas-Martínez, Vanesa Garrido-Rodríguez, Gabriel Bernal-Blanco, Alejandro Suárez-Benjumea, Ana Isabel Álvarez-Ríos, Carmen Lozano, Carmen González-Corvillo, Marta Suñer-Poblet, Francisco Manuel González-Roncero, Berta Sánchez, Isabel Maldonado-Calzado, José Manuel Lara-Ruiz, María Francisca Gonzalez-Escribano, Yolanda María Pacheco. Factors associated with the humoral response after three doses of COVID-19 vaccination in kidney transplant recipients. Frontiers in Immunology 2023; 14 doi: 10.3389/fimmu.2023.1099079
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| 12 |
Lisa K. Torres, Peter Pickkers, Tom van der Poll. Sepsis-Induced Immunosuppression. Annual Review of Physiology 2022; 84(1) doi: 10.1146/annurev-physiol-061121-040214
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| 13 |
Cesidio Giuliani, Sara Verrocchio, Fabio Verginelli, Ines Bucci, Antonino Grassadonia, Giorgio Napolitano. Hormonal Regulation of the MHC Class I Gene in Thyroid Cells: Role of the Promoter “Tissue-Specific” Region. Frontiers in Endocrinology 2021; 12 doi: 10.3389/fendo.2021.749609
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| 14 |
Ranjit Joshi, Sheetal Yogesh Patil, Sachin Gawale, Prathmesh Parekh, Trupti Jugansingh Dhakare, Nitin Salunke, Rajeev Agarwal. Efficacy of thymosin alpha-1 as an immunomodulatory adjuvant in patients with recurrent implantation failure: a real-world retrospective analysis. International Journal of Reproduction, Contraception, Obstetrics and Gynecology 2026; 15(4) doi: 10.18203/2320-1770.ijrcog20260885
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| 15 |
Anastasios I. Birmpilis, Panagiotis Vitsos, Ioannis V. Kostopoulos, Lillian Williams, Kyriaki Ioannou, Pinelopi Samara, Chrysoula-Evangelia Karachaliou, Ioannis F. Voutsas, Elena Alyfanti, Nikolaos Angelis, Nikolaos G. Gavalas, Themis Gkraikou, Niki Kappa, Eleftheria Klagkou, Persefoni Klimentzou, Spiridoula Nikou, Nikos E. Papaioannou, Margarita Skopeliti, David Toukli, Meletios-Athanasios Dimopoulos, Aristotelis Bamias, Evangelia Livaniou, Hubert Kalbacher, Ourania E. Tsitsilonis, Wolfgang Voelter. Prothymosin α and its C-Terminal Immunoreactive Decapeptide
Show No Evidence of Acute Toxicity: A Preliminary In Silico, In Vitro
and In Vivo Investigation. Current Medicinal Chemistry 2022; 29(42) doi: 10.2174/0929867328666211117093401
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| 16 |
Michael Quagliata, Anna Maria Papini, Paolo Rovero. Therapeutic applications of thymosin peptides: a patent landscape 2018-present. Expert Opinion on Therapeutic Patents 2023; 33(12) doi: 10.1080/13543776.2023.2298833
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| 17 |
Adriana Marques, Carla Torre, Rui Pinto, Bruno Sepodes, João Rocha. Treatment Advances in Sepsis and Septic Shock: Modulating Pro- and Anti-Inflammatory Mechanisms. Journal of Clinical Medicine 2023; 12(8) doi: 10.3390/jcm12082892
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| 18 |
Rahaman Shaik, Sai Geethika Laddika, Madiha Unnisa, Anas Hamza, Shireen Begum, Syeda Fatima Sarwar. Drug Repurposing in Oncology: A Strategic Pathway to Unlocking New Therapeutic Potential. Therapeutic Innovation & Regulatory Science 2026; 60(2) doi: 10.1007/s43441-025-00895-8
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| 19 |
Christian Bode, Sebastian Weis, Andrea Sauer, Pedro Wendel-Garcia, Sascha David. Targeting the host response in sepsis: current approaches and future evidence. Critical Care 2023; 27(1) doi: 10.1186/s13054-023-04762-6
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| 20 |
Maria A. Simonova, Igor Ivanov, Natalia S. Shoshina, Alina M. Komyakova, Dmitry A. Makarov, Denis S. Baranovskii, Ilya D. Klabukov, Kristina P. Telepenina, Dmitrii A. Atiakshin, Peter V. Shegay, Andrey D. Kaprin, Vasiliy N. Stepanenko. Aging and Thymosin Alpha-1. International Journal of Molecular Sciences 2025; 26(23) doi: 10.3390/ijms262311470
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| 21 |
Mercedes Vitek, Alenka Zvonar Pobirk, Robert Roškar, Mirjam Gosenca Matjaž.
Exploiting the potential of
in situ
forming liquid crystals: development and
in vitro
performance of long-acting depots for peptide drug thymosin alpha 1 subcutaneous administration
. Drug Delivery 2025; 32(1) doi: 10.1080/10717544.2025.2460708
|
| 22 |
Wilson Savino, Ailin Lepletier. Thymus-derived hormonal and cellular control of cancer. Frontiers in Endocrinology 2023; 14 doi: 10.3389/fendo.2023.1168186
|
| 23 |
Viktor Wixler, Rafael Leite Dantas, Georg Varga, Yvonne Boergeling, Stephan Ludwig. Small Spleen Peptides (SSPs) Shape Dendritic Cell Differentiation through Modulation of Extracellular ATP Synthesis Profile. Biomolecules 2024; 14(4) doi: 10.3390/biom14040469
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| 24 |
Daniela Ricci, Marilena Paola Etna, Martina Severa, Stefano Fiore, Fabiana Rizzo, Marco Iannetta, Massimo Andreoni, Stefano Balducci, Paola Stefanelli, Anna Teresa Palamara, Eliana Marina Coccia. Novel evidence of Thymosin α1 immunomodulatory properties in SARS-CoV-2 infection: Effect on innate inflammatory response in a peripheral blood mononuclear cell-based in vitro model. International Immunopharmacology 2023; 117 doi: 10.1016/j.intimp.2023.109996
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| 25 |
María del Mar Pozo-Balado, Ángel Bulnes-Ramos, Israel Olivas-Martínez, Vanesa Garrido-Rodríguez, Carmen Lozano, Ana I. Álvarez-Ríos, Berta Sánchez-Sánchez, Encarnación Sánchez-Bejarano, Isabel Maldonado-Calzado, José Manuel Martín-Lara, Juan Antonio Santamaría, Rafael Bernal, María Francisca González-Escribano, Manuel Leal, Yolanda M. Pacheco. Higher plasma levels of thymosin-α1 are associated with a lower waning of humoral response after COVID-19 vaccination: an eight months follow-up study in a nursing home. Immunity & Ageing 2023; 20(1) doi: 10.1186/s12979-023-00334-y
|
| 26 |
ChenLu Huang, Ling Fei, Wei Xu, WeiXia Li, XuDong Xie, Qiang Li, Liang Chen. Efficacy Evaluation of Thymosin Alpha 1 in Non-severe Patients With COVID-19: A Retrospective Cohort Study Based on Propensity Score Matching. Frontiers in Medicine 2021; 8 doi: 10.3389/fmed.2021.664776
|
| 27 |
THYMOSINE, A T CELL MODULATOR IN COVID-19. International Journal of Current Pharmaceutical Research 2026; doi: 10.22159/ijcpr.2026v18i1.8039
|
| 28 |
Hong Wang, Lixia Wang, Heqing Zhong, Zhendong Li. Thymosin α1 Combined with PD-1/PD-L1 Inhibitor Plus Chemotherapy in Platinum-Resistant Recurrent Ovarian Cancer : A Retrospective Analysis. Cancer Management and Research 2025; doi: 10.2147/CMAR.S542744
|
| 29 |
Kai Hu, Linlin Liang, Jian Song. Development of a ROS-responsive, glutathione-functionalized injectable hydrogel system for controlled drug release. Journal of Biomaterials Applications 2025; 40(2) doi: 10.1177/08853282251334208
|
| 30 |
Tiffany Y.-C. Tang, Yupeng Li, Peter Chapman, Emad Tajkhorshid, Aditi Das. Elucidating the binding and metabolic interactions of sunitinib and sorafenib with Cytochrome P450s CYP2U1 and CYP2D6. Molecular Pharmacology 2026; 108(4) doi: 10.1016/j.molpha.2026.100114
|
| 31 |
Yafeng Liu, Jibin Lu. Mechanism and clinical application of thymosin in the treatment of lung cancer. Frontiers in Immunology 2023; 14 doi: 10.3389/fimmu.2023.1237978
|
| 32 |
Changpeng Cui, Qingji Huo, Xue Xiong, Sungsoo Na, Masaru Mitsuda, Kazumasa Minami, Baiyan Li, Hiroki Yokota. P18: Novel Anticancer Peptide from Induced Tumor-Suppressing Cells Targeting Breast Cancer and Bone Metastasis. Cancers 2024; 16(12) doi: 10.3390/cancers16122230
|
| 33 |
Andrea Öhlander, Carsten Lüdtke, Artur Sahakjan, Richard E. Johnsson. N‐Butylpyrrolidinone is an equally good solvent as N,N‐dimethylformamide for microwave assisted solid phase peptide synthesis. Journal of Peptide Science 2024; 30(10) doi: 10.1002/psc.3612
|
| 34 |
Laura Solmonese, Maria Fortunata Lofiego, Carolina Fazio, Francesco Marzani, Francesca Piazzini, Emma Bello, Fabrizio Celesti, Gianluca Giacobini, Xiaohui Wang, Michele Maio, Sandra Coral, Anna Maria Di Giacomo, Alessia Covre. The Immunomodulatory Activity of Thymosin Alpha 1 on Tumor Cell Lines and Distinct Immune Cell Subsets. OncoTargets and Therapy 2025; doi: 10.2147/OTT.S527785
|
| 35 |
Shuai Wang, Wei Wei, Hui Yong, Zhao Zhang, Xiping Zhang, Xuejun Zhang, Shue Wang. Synergistic anti-cancer and attenuation effects of thymosin on chemotherapeutic drug vinorelbine in tumor-bearing zebrafish. Biomedicine & Pharmacotherapy 2023; 162 doi: 10.1016/j.biopha.2023.114633
|
| 36 |
Anju Surendranath, Adna Mohammed Adan, Alanoud Abdulla, Fatima Hakeem, Warda Berair Mustafa Abdelgani, Ammira S. Al-Shabeeb Akil, Ajaz A. Bhat. Immunomodulators - Part A. Advances in Protein Chemistry and Structural Biology 2026; 151 doi: 10.1016/bs.apcsb.2026.02.002
|
| 37 |
Smriti Mishra, Gaurang Telang, Anurag Sureshbabu, Samruddhi Kulkarni, Senthil Thayagrajan, A.W Santhosh Kumar, Rajshri Singh. A multipronged Tα1 reset of CD8+ T cell cytotoxicity against breast cancer. Human Immunology 2026; 87(3) doi: 10.1016/j.humimm.2026.111678
|
| 38 |
Arto Yuwono Soeroto, Hendarsyah Suryadinata, Theo Audi Yanto, Timotius Ivan Hariyanto. The efficacy of thymosin alpha-1 therapy in moderate to critical COVID-19 patients: a systematic review, meta-analysis, and meta-regression. Inflammopharmacology 2023; 31(6) doi: 10.1007/s10787-023-01354-2
|
| 39 |
念 刘. Current Status of Prognostic Evaluation Model and Treatment of Acute-on-Chronic Liver Failure. Advances in Clinical Medicine 2024; 14(04) doi: 10.12677/acm.2024.1441320
|
| 40 |
Monika Besman, Aleksandra Zambrowicz, Magdalena Matwiejczyk. Review of Thymic Peptides and Hormones: From Their Properties to Clinical Application. International Journal of Peptide Research and Therapeutics 2024; 31(1) doi: 10.1007/s10989-024-10666-y
|
| 41 |
Hannah Kunstek, Janneke Kieviet, Caroline Lindemans, Coco de Koning, Stefan Nierkens. Thymic peptides in immune reconstitution and clinical outcome after allogeneic hematopoietic cell transplantation. Blood Neoplasia 2025; 2(2) doi: 10.1016/j.bneo.2025.100090
|
| 42 |
Expert Consensus on the Clinical Application of Thymosin Alpha 1 in Infectious Diseases and Critical Care Medicine. Infectious Microbes and Diseases 2025; 7(2) doi: 10.1097/IM9.0000000000000176
|
| 43 |
Ting Li, Bao‐Liang Wu, Cai‐Long Yu, Liang‐Yan Jin. A Case Report of a Multisystemic Immune‐Related Adverse Event Caused by Sintilimab in Combination With Thymosin Alpha‐1. Clinical Case Reports 2026; 14(2) doi: 10.1002/ccr3.72025
|
| 44 |
Yan Wu, Lingling He, Yongping Guo, Niansong Wang. Risk Factors and Drug Efficacy for Severe Illness in Hemodialysis Patients Infected with the Omicron Variant of COVID-19. Kidney and Blood Pressure Research 2023; 48(1) doi: 10.1159/000534192
|
| 45 |
Zirui Wang, Cong Wang, Xiaohua Fei, Haixing Wu, Peiqin Niu, Changxing Shen. Thymalfasin therapy accelerates COVID-19 pneumonia rehabilitation through anti-inflammatory mechanisms. Pneumonia 2023; 15(1) doi: 10.1186/s41479-023-00116-6
|
| 46 |
Tao Liu, Shengdong Liu, Tao Li, Jingjing Zhang. Thymosin a1 use is not associated with reduced COVID-19 mortality. The American Journal of Emergency Medicine 2022; 53 doi: 10.1016/j.ajem.2021.04.043
|
| 47 |
C. J. Reuß, M. Bernhard, C. Beynon, M. O. Fiedler-Kalenka, A. Hecker, C. Jungk, D. Michalski, F. C. F. Schmitt, M. A. Weigand, T. Brenner, M. Dietrich, C. Nusshag. Fokus Sepsis und allgemeine Intensivmedizin 2024/2025. Die Anaesthesiologie 2025; 74(10) doi: 10.1007/s00101-025-01589-4
|
| 48 |
Enrico Garaci, Maurizio Paci, Claudia Matteucci, Claudio Costantini, Paolo Puccetti, Luigina Romani. Phenotypic drug discovery: a case for thymosin alpha-1. Frontiers in Medicine 2024; 11 doi: 10.3389/fmed.2024.1388959
|
| 49 |
Snigdha Ranjan, Shagun Arya, Mugdha Pradhan. The Peptide Revolution in Autoimmune Disease: Mechanisms, Clinical Evidence, and Translational Potential. International Journal of Science and Healthcare Research 2026; doi: 10.52403/ijshr.20260110
|