Prediction of delayed graft function using different scoring algorithms: A single-center experience

Table 1 Comparison of variables used in different scoring systems

	DGF risk calculator (Irish et al[9])	DGFS scoring system (Chapal et al[11])	Jeldres scoring system (Jeldres et al[10])
Recipient variables
Recipient BMI	+	+	-
Recipient age	+	-	+
No. of HLA mismatches	+	-	+
Peak PRA (%)	+	-	+
Recipient race	+	-	-
Recipient gender	+	-	-
Duration of dialysis	+	-	-
History of diabetes mellitus	+	-	-
Previous transplantation or blood transfusion	+	-	-
Single or multiple organ transplant	+	-	-
Recipient weight	-	-	+
Donor variables
Donor age	+	+	+
Duration of CIT	+	+	+
Terminal serum creatinine	+	+	-
Donor weight	+	-	-
Primary cause of death	+	-	-
History of hypertension	+	-	-
Duration of WIT	+	-	-
Type of the donor (living, DCD)	+	-	-
Type of induction therapy	-	+	-

PRA: Panel-reactive antibody; WIT: Warm ischemia time; CIT: Cold ischemia time; DCD: Donation after cardiac death; DGF: Delayed graft function.

Table 2 Recipient characteristics at the time of transplantation

Age (yr)	50.2 ± 11.92
Origin (%)
Blacks	4.5
Caucasians	95.5
Gender (%)
Male	61.9
History of diabetes mellitus (%)
Yes	16.6
Body mass index (kg/m²)	25.1 ± 3.82
Pretransplant transfusions (%)
Yes	38.1
No	56.7
Unknown	5.3
Duration of the pre-transplant renal replacement therapy (mo)	26.7 (16.4-43.5)1
Peak panel-reactive antibodies (%)	88.5
≤ 5%	9.5
5%-80%	2
≥ 80%
Proportion of kidney re-graft (%)	12.6
Total HLA mismatches	3 (2-3)1

¹Median with P25-75;

²Mean ± standard deviation (SD).

Table 3 Donor characteristics at the time of transplantation

Age (yr)	45.1 ± 14.12
Weight (kg)	76.2 ± 16.42
History of hypertension (%)
Yes	23.1
No	74.5
Unknown	2.4
Terminal serum creatinine (mg/dL)	0.78 (0.61-1.00)1
Donor type (%)
Standard criteria donor	68.8
Extended criteria donor	17
Donation after cardiac death donor	14.2
Primary cause of death (%)
Cerebrovascular accident/stroke	27.1
Anoxia	8.1
Other	64.8
Cold ischemia time (h)	14 ± 4.72
Second warm ischemia time (min)	32.8 ± 7.92

¹Median with P25-75;

²Mean ± standard deviation (SD).

Table 4 Observed prevalence vs predicted probability of delayed graft function in the overall population and by risk group

Kidney graft according to donor type	Observed prevalence of DGF (%)	Probability of DGF predicted by the DGF risk calculator (%) (Irish et al[9])	Probability of DGF predicted by the DGF scoring system (%) (Chapal et al[11])	Probability of DGF predicted by the Jeldres scoring system (%) (Jeldres et al[10])
Overall population (n = 247)	15.3	161	19.71	251
		12-242	13.6-262	14-402
		0.693	0.513	0.543
Standard criteria donor (n = 170)	11.8	141	20.11	211
		10-202	14.5-26.42	13.7-34.22
		0.733	0.603	0.543
Extended criteria donor (n = 42)	19	19.51	21.21	41.51
		14-252	14.4-27.62	25.7-602
		0.393	0.343	0.383
Donation after cardiac death (n = 35)	28.6	301	11.81	211
		18-382	9.1-20.42	8-392
		0.653	0.583	0.643

¹Median;

²P25-P75;

³AUC of the ROC curve. DGF: Delayed graft function.