Geographical disparities for liver transplantation access in Mexico

Table 1 Assessment of overall access to liver transplantation according to the State of residence in Mexico between 2014 and 2023

Variable	LT states	Rest	P value
Population (millions)	39.7, 2.5	84.4, 4.6	< 0.001
Liver disease mortality rate per 10000	3.1, 0.3	3.2, 0.1	0.047
Listings per million	3.8, 1.5	1.2, 0.6	< 0.001
O:E listings	1.3, 0.4	0.4, 0.2	< 0.001
T:L ratio	70%	63.6%	< 0.001
Mortality	15.2%	19.4%	0.006

Liver transplantation states refers to Mexico City & State, Jalisco and Nuevo León. Values are expressed as median and interquartile range. LT: Liver transplantation.

Table 2 Assessment of access to liver transplantation over time according to the State of residence in Mexico between 2014 and 2023

Variable	LT states	Rest	P value
Waiting time (days)	74.3, 23.7	56.4, 33	0.42
Time until transplant (days)	51, 117	53, 132	0.56
Transplant rate at 90 days	45%	40.9%	0.046
Mortality rate at 90 days	9.1%	11.1%	0.10
Transplants per 100 person-years	151.7, 107.3	93.4, 105.1	0.11
Deaths per 100 person-years	38.2, 23.3	26.9, 28	0.8

Liver transplantation States refers to Mexico City & State, Jalisco and Nuevo León. Values are expressed as median and interquartile range. LT: Liver transplantation.

Table 3 Multivariate Cox regression analysis assessing the effect of being a resident of Mexico City & State, Jalisco or Nuevo Leon on the likelihood of being transplanted over time, controlled by age, gender, ABO group and healthcare affiliation

Variable	Hazard ratio	95%CI	P value
Age (adult vs pediatric)	1.57	1.36-1.8	< 0.001
Gender (male vs female)	1.1	0.99-1.21	0.06
ABO group (reference group 0)
Group A	1.24	1.12-1.39	< 0.001
Group B	1.08	0.91-1.27	0.38
Group AB	1.29	0.9-1.86	0.166
Healthcare Sector (public vs private)	0.98	0.89-1.11	0.977
Residence (LT state vs rest)	1.14	1.03-1.26	0.009