©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Transplant. Jun 24, 2016; 6(2): 314-320
Published online Jun 24, 2016. doi: 10.5500/wjt.v6.i2.314
Published online Jun 24, 2016. doi: 10.5500/wjt.v6.i2.314
Potential approaches to improve the outcomes of donation after cardiac death liver grafts
Paria Mahboub, Department of Surgery, Groningen Transplant Center, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands
Paria Mahboub, Adel Bozorgzadeh, Paulo N Martins, Department of Surgery, Division of Transplantation, University of Massachusetts, Worcester, MA 01655, United States
Author contributions: Mahboub P wrote the manuscript; Bozorgzadeh A and Martins PN contributed to writing the manuscript.
Supported by University of Massachusetts (FDSP grant to Paulo N Martins).
Conflict-of-interest statement: The authors declare no conflicts of interest.
Correspondence to: Paulo N Martins, MD, PhD, Department of Surgery, Division of Transplantation, University of Massachusetts, 55 Lake Avenue North, Worcester, MA 01655, United States. paulo.martins@umassmemorial.org
Telephone: +1-508-3342023
Received: July 18, 2015
Peer-review started: July 19, 2015
First decision: September 17, 2015
Revised: December 24, 2015
Accepted: March 24, 2016
Article in press: March 25, 2016
Published online: June 24, 2016
Processing time: 340 Days and 12.7 Hours
Peer-review started: July 19, 2015
First decision: September 17, 2015
Revised: December 24, 2015
Accepted: March 24, 2016
Article in press: March 25, 2016
Published online: June 24, 2016
Processing time: 340 Days and 12.7 Hours
Core Tip
Core tip: As the demand for more organs increases, the transplant community searches for new approaches to expand the pool of organs. Recently developed methods to improve the condition of donation after cardiac death (DCD) livers look promising. During the past decade, ex vivo machine perfusion method has demonstrated positive results and it is considered as a new potential preservation method for DCD organs. This paper provides an overview of the attempts to ameliorate the quality of DCD liver grafts and transplant outcomes by improving preservation techniques.