Copyright
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Association of vascular invasion and tumor differentiation on post-liver transplant outcomes in patients with hepatocellular carcinoma
Nazlı Begüm Öztürk, Merve M Gurakar, Ximena Parraga, Marwan Alsaqa, Leandro Sierra, Emily Currier, Butros Fakhoury, Alan Bonder, Ahmet Gurakar, Behnam Saberi
Nazlı Begüm Öztürk, Department of Gastroenterology and Hepatology, St. Louis University, St. Louis, MO 63104, United States
Merve M Gurakar, Department of Gastroenterology and Hepatology, Johns Hopkins School of Medicine, Baltimore, MD 21205, United States
Ximena Parraga, Marwan Alsaqa, Emily Currier, Alan Bonder, Behnam Saberi, Department of Gastroenterology and Hepatology, Beth Israel Deaconess Medical Center, Boston, MA 02215, United States
Leandro Sierra, Department of Internal Medicine, Cleveland Clinic Foundation, Cleveland, OH 44195, United States
Butros Fakhoury, Department of Internal Medicine, Virginia Commonwealth University, Richmond, VA 23220, United States
Ahmet Gurakar, Department of Gastroenterology and Hepatology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, United States
Author contributions: Gurakar A and Saberi B were responsible for supervision and conception and design; Öztürk NB, Gurakar MM, Parraga X, Alsaqa M, Sierra L, Currier E, Fakhoury B, Bonder A, Gurakar A, and Saberi B were responsible for writing and revisions; all of the authors read and approved the final version of the manuscript to be published.
Institutional review board statement: The data reported were supplied by the United Network for Organ Sharing (UNOS), as the contractor for the Organ Procurement Transplant Network (OPTN). Because UNOS is a publicly available, deidentified, patient-level database, informed consent and ethical approval were not required according to the policies of UNOS and the Institutional Review Board at Beth Israel Deaconess Medical Center.
Informed consent statement: The data reported were supplied by the United Network for Organ Sharing (UNOS), as the contractor for the Organ Procurement Transplant Network (OPTN). Because UNOS is a publicly available, deidentified, patient-level database, informed consent and ethical approval were not required according to the policies of UNOS and the Institutional Review Board at Beth Israel Deaconess Medical Center.
Conflict-of-interest statement: Authors report no conflict of interest.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Data sharing statement: United Network for Organ Sharing database is publicly available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
https://creativecommons.org/Licenses/by-nc/4.0/ Corresponding author: Ahmet Gurakar, MD, Department of Gastroenterology and Hepatology, Johns Hopkins University School of Medicine, 720 Rutland Avenue, Ross Research Building, Suite 918, Baltimore, MD 21205, United States.
aguraka1@jhmi.edu
Received: May 16, 2025
Revised: June 19, 2025
Accepted: September 22, 2025
Published online: December 18, 2025
Processing time: 187 Days and 11.5 Hours
