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Retrospective Study
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Transplant. Jun 18, 2025; 15(2): 99554
Published online Jun 18, 2025. doi: 10.5500/wjt.v15.i2.99554
Urinary tract infections in kidney transplant patients admitted to hospital: A real-life experience
Biagio Pinchera, Rosa Carrano, Elisa Schettino, Alessia D'Agostino, Emilia Trucillo, Federica Cuccurullo, Fabrizio Salemi, Amerigo Piccione, Ivan Gentile
Biagio Pinchera, Alessia D'Agostino, Emilia Trucillo, Federica Cuccurullo, Ivan Gentile, Section of Infectious Diseases, Department of Clinical Medicine and Surgery, University of Naples “Federico II”, Naples 80131, Italy
Rosa Carrano, Elisa Schettino, Fabrizio Salemi, Amerigo Piccione, Section of Nephrology, Department of Public Health, University of Naples “Federico II”, Naples 80131, Italy
Co-first authors: Biagio Pinchera and Rosa Carrano.
Author contributions: Pinchera B conceptualized the study; Schettino E, Salemi F, and Piccione A designed the methodology; Schettino E, D’Agostino A, Trucillo E, and Cuccurullo F provided critical software; Carrano R and Gentile I performed the validation of the data; Pinchera B performed the formal data analyses; Pinchera B, Schettino E, D’Agostino A, and Trucillo E performed the investigations; Carrano R, Schettino E, Salemi F, and Piccione A provided critical resources; Schettino E performed the data curation; Pinchera B and Gentile I performed the drafting, writing, review and editing of the manuscript; Pinchera B, Carrano R, and Gentile I provided the data visualization; Carrano R and Gentile I supervised the study; Pinchera B provided project administration; All authors have read and agreed to the published version of the manuscript. The designation of co-first authorship is merited by Pinchera B and Carrano R for their collaborative activities in design of the study and acquisition and analysis of the data.
Institutional review board statement: Ethical approval was obtained from the Ethics Committee of the Federico II University Hospital of Naples, on November 20, 2022 with the number 104/22.
Informed consent statement: The patients provided their written informed consent to participate in this study.
Conflict-of-interest statement: The authors declare no conflicts of interest.
Data sharing statement: Data requests may be made directly to the corresponding author via email.
Corresponding author: Biagio Pinchera, MD, Doctor, Section of Infectious Diseases, Department of Clinical Medicine and Surgery, University of Naples “Federico II”, Via Sergio Pansini, n.5, Naples 80131, Italy. biapin89@virgilio.it
Received: July 24, 2024
Revised: November 7, 2024
Accepted: November 28, 2024
Published online: June 18, 2025
Processing time: 211 Days and 11.8 Hours
Core Tip

Core Tip: From our real-life experience, infection with multidrug-resistant germs was confirmed as a risk factor for the severe evolution of the infection. At the same time, the re-evaluation of immunosuppressive therapy may be an important therapeutic strategy in the course of infection. Prompt initiation of empiric antibiotic therapy upon initiation of microbiological investigations may reduce the risk of severe infection progression.