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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Transplant. Mar 18, 2025; 15(1): 100413
Published online Mar 18, 2025. doi: 10.5500/wjt.v15.i1.100413
Published online Mar 18, 2025. doi: 10.5500/wjt.v15.i1.100413
King's College criteria and the Clichy-Villejuif criteria require adjustments for assessing acute liver failure due to yellow fever
Bruno da Silva Athanasio, Cristiano Xavier Lima, Department of Surgery, Federal University of Minas Gerais, Belo Horizonte 30130-100, Minas Gerais, Brazil
Antonio Marcio de Faria Andrade, Juliano Felix Castro, Silverio Leonardo Macedo Garcia, Liver Transplantation Unit, Felicio Rocho Hospital, Belo Horizonte 30110-934, Minas Gerais, Brazil
Vivian Vasconcelos Costa, Daniele da Gloria Souza, Department of Morphology, Federal University of Minas Gerais, Belo Horizonte 31270-901, Minas Gerais, Brazil
Mauro Martins Teixeira, Department of Biochemistry and Immunology, Federal University of Minas Gerais, Belo Horizonte 31270-901, Minas Gerais, Brazil
Paula Vieira Teixeira Vidigal, Department of Pathology, Federal University of Minas Gerais, Belo Horizonte 30130-100, Minas Gerais, Brazil
Co-first authors: Bruno da Silva Athanasio and Antonio Marcio de Faria Andrade.
Author contributions: Athanasio BDS and Andrade AMF conducted the study and wrote the paper; Costa VV, Teixeira MM, and Souza DDG provided clinical advice and help writing the actual manuscript; Castro JF and Garcia SLM conducted the study and collect data from clinical cases; Vidigal PVT and Lima CX supervised all phases of the study; all of the authors read and approved the final version of the manuscript to be published.
Supported by The INCT-CNPq Program, No. 465425/2014-3.
Institutional review board statement: This study was reviewed and approved by the Ethics Committee of the Felicio Rocho Hospital, No. 2.851.504.
Informed consent statement: All patients provided informed consent to participate in the study.
Conflict-of-interest statement: All the authors report no conflicts of interest for this article.
Data sharing statement: No additional data are available.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Cristiano Xavier Lima, MD, PhD, Associate Professor, Department of Surgery, Federal University of Minas Gerais, 190-Bairro Santa Efigênia, Belo Horizonte 30130-100, Minas Gerais, Brazil. cxlima@ufmg.br
Received: August 15, 2024
Revised: October 3, 2024
Accepted: November 1, 2024
Published online: March 18, 2025
Processing time: 103 Days and 21.1 Hours
Revised: October 3, 2024
Accepted: November 1, 2024
Published online: March 18, 2025
Processing time: 103 Days and 21.1 Hours
Core Tip
Core Tip: This study describes the application of current liver transplantation (LT) scoring systems, the King's College criteria and the Clichy-Villejuif criteria, for predicting outcomes in patients with acute liver failure (ALF) due to yellow fever (YF). We focused on 14 patients with confirmed ALF due to YF who were monitored by a liver transplant team during an epidemic in Brazil. Four patients underwent emergency LT following adaptations to the aforementioned scoring systems. The 5-year survival rate was 50%. These findings highlight the need to revise the criteria for transplantation for YF-associated ALF and demonstrate that LT can be a viable, life-saving option in specific cases.