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Retrospective Study
©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Transplant. Jun 18, 2024; 14(2): 92528
Published online Jun 18, 2024. doi: 10.5500/wjt.v14.i2.92528
Portal vein arterialization in 25 liver transplant recipients: A Latin American single-center experience
Nicolas Andres Cortes-Mejia, Diana Fernanda Bejarano-Ramirez, Juan Jose Guerra-Londono, Diego Rymel Trivino-Alvarez, Raquel Tabares-Mesa, Alonso Vera-Torres
Nicolas Andres Cortes-Mejia, Juan Jose Guerra-Londono, Division of Anesthesiology, Critical Care Medicine, and Pain Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, United States
Nicolas Andres Cortes-Mejia, Diana Fernanda Bejarano-Ramirez, Diego Rymel Trivino-Alvarez, Alonso Vera-Torres, Transplant and Hepatobiliary Surgery Department, Fundacion Santa Fe de Bogota, Bogota 110111, Colombia
Raquel Tabares-Mesa, General Surgery Department, Fundacion Santa Fe de Bogota, Bogota 110111, Colombia
Author contributions: Vera-Torres A is the Transplant Surgeon and director of the Transplantation program at Fundacion Santa Fe de Bogota, he proposed and performed the technique for these liver transplant recipients; Cortes-Mejia NA, Vera-Torres A, and Bejarano-Ramirez DF designed the research study; Cortes-Mejia NA and Trivino-Alvarez DR performed the primary literature review; Cortes-Mejia NA performed data extraction; Bejarano-Ramirez DF and Cortes-Mejia NA performed the statistical analysis; Vera-Torres A, Cortes-Mejia NA and Guerra-Londono JJ wrote the manuscript; Vera-Torres A, and Guerra-Londono JJ were responsible for revising the manuscript for important intellectual content; and all authors read and approved the final version. Tabares-Mesa R is a general surgeon, and she drew the pictures illustrating the surgical intervention analyzed during this manuscript.
Institutional review board statement: Data collection, analysis, and publication were approved by the Fundacion Santa Fe de Bogota Corporative Ethics Committee for Research (CCEI) (act CCEI-15197-2023) on March 28, 2023. The authors acted according to the Helsinki and Istanbul Declarations of ethical principles.
Informed consent statement: Because of its retrospective nature, the requirement for written consent was waived by the CCEI.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: For further supplementary, multimedia, statistical code, and dataset, please contact the corresponding author at email address rural.trasplantes@fsfb.org.co.
Corresponding author: Alonso Vera-Torres, FACS, FEBS, MD, Chief Doctor, Professor, Surgeon, Transplant and Hepatobiliary Surgery Department, Fundacion Santa Fe de Bogota, Cra. 7 #117-15. Fourth Floor, Transplantation Office, Bogota 110111, Colombia. alonso.vera@fsfb.org.co
Received: January 28, 2024
Revised: February 19, 2024
Accepted: April 28, 2024
Published online: June 18, 2024
Processing time: 137 Days and 9.9 Hours
Core Tip

Core Tip: Guaranteeing adequate graft perfusion is essential to obtain optimal outcomes after liver transplantation (LT). This retrospective single-center study analyzed 25 cases of portal vein arterialization (PVA) for portal flow optimization in LT. To account for the time-sensitive effect, cases were classified into two groups: prereperfusion (pre-PVA) if the arterioportal anastomosis was performed before graft revascularization and postreperfusion (post-PVA) if PVA was performed afterward. We found that pre-PVA yields better results than post-PVA and that hyperperfusion could play a protective role against graft dysfunction. Currently, this is the largest case series studying PVA during LT.