Observational Study
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Transplant. Jun 18, 2023; 13(4): 183-189
Published online Jun 18, 2023. doi: 10.5500/wjt.v13.i4.183
Haemodynamic management in brain death donors: Influence of aetiology of brain death
Chiara Lazzeri, Manuela Bonizzoli, Stefano Batacchi, Cristiana Guetti, Walter Vessella, Alessandra Valletta, Alessandra Ottaviano, Adriano Peris
Chiara Lazzeri, Manuela Bonizzoli, Stefano Batacchi, Cristiana Guetti, Walter Vessella, Alessandra Valletta, Alessandra Ottaviano, Adriano Peris, Department of Emergency, Intensive Care Unit and Extracorporeal Membrane Oxygenation Center, Florence 50134, Italy
Author contributions: Lazzeri C, Bonizzoli M, and Peris A designed the research study; Guetti C, Batacchi S, and Ottaviano A performed the research; Valletta A and Vessella W analyzed the data and wrote the manuscript; all authors have read and approved the final manuscript.
Institutional review board statement: The study protocol was approved by our Internal Editorial Board.
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data.
Conflict-of-interest statement: All the authors declare that they have no conflict of interest to disclose.
Data sharing statement: No additional data are available.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Chiara Lazzeri, MD, Chief Physician, Senior Researcher, Department of Emergency, Intensive Care Unit and Extracorporeal Membrane Oxygenation Center, Largo Brambilla 3, Florence 50134, Italy. lazzeri.ch@gmail.com
Received: December 20, 2022
Peer-review started: December 20, 2022
First decision: February 20, 2023
Revised: February 28, 2023
Accepted: April 21, 2023
Article in press: April 21, 2023
Published online: June 18, 2023
Processing time: 177 Days and 16.9 Hours
Core Tip

Core Tip: In our single centre observational study including 138 brain death donors (BDDs), haemodynamic management is affected by the aetiology of brain death. BDDs with postanoxic encephalopathy had higher requirements for norepinephrine and other vasoactive drugs.