©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Transplant. Nov 18, 2022; 12(11): 347-358
Published online Nov 18, 2022. doi: 10.5500/wjt.v12.i11.347
Published online Nov 18, 2022. doi: 10.5500/wjt.v12.i11.347
Challenges in liver transplantation in the context of a major pandemic
Eleni Theocharidou, 2nd Department of Internal Medicine, Aristotle University of Thessaloniki, Konstantinoupoleos 49, 54642, Thessaloniki, Greece
Danielle Adebayo, Department of Gastroenterology and Hepatology, Royal Berkshire NHS Foundation Trust, London Road, Reading, RG1 5AN, United Kingdom
Author contributions: Theocharidou E reviewed the literature, wrote the paper and approved the final draft. Adebayo D reviewed the literature, critically revised the paper and approved the final draft.
Conflict-of-interest statement: All authors declare that they have no conflict of interest.
Corresponding author: Eleni Theocharidou, PhD, 2nd Department of Internal Medicine, Aristotle University of Thessaloniki, Konstantinoupoleos 49, 54642, Thessaloniki, Greece.
Received: June 9, 2022
Peer-review started: June 9, 2022
First decision: July 13, 2022
Revised: August 27, 2022
Accepted: September 22, 2022
Article in press: September 22, 2022
Published online: November 18, 2022
Processing time: 160 Days and 10.1 Hours
Peer-review started: June 9, 2022
First decision: July 13, 2022
Revised: August 27, 2022
Accepted: September 22, 2022
Article in press: September 22, 2022
Published online: November 18, 2022
Processing time: 160 Days and 10.1 Hours
Core Tip
Core Tip: Coronavirus disease-2019 pandemic posed unprecedented challenges in terms of managing patients with advanced liver disease remotely, offering transplant for highly selected patients, managing immunosuppression, treating infected patients with chronic liver disease, transplanting infected patients, and utilizing grafts from infected donors. The transplant community responded rapidly to these challenges and many centers were able to resume activity soon after the first wave of the pandemic. Emerging data help shed light on areas of uncertainty and provide guidance for future challenges.