Clinical Trials Study
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Transplant. Apr 29, 2020; 10(4): 79-89
Published online Apr 29, 2020. doi: 10.5500/wjt.v10.i4.79
Listening to music during arteriovenous fistula surgery alleviates anxiety: A randomized single-blind clinical trial
Sanem Guler Cimen, Ebru Oğuz, Ayse Gokcen Gundogmus, Sertac Cimen, Fatih Sandikci, Mehmet Deniz Ayli
Sanem Guler Cimen, Department of General Surgery, Diskapi Research and Training Hospital, Health Sciences University, Ankara 06110, Turkey
Ebru Oğuz, Mehmet Deniz Ayli, Division of Nephrology, Department of Internal Medicine, Diskapi Research and Training Hospital, Health Sciences University, Ankara 06110, Turkey
Ayse Gokcen Gundogmus, Department of Psychiatry, Diskapi Research and Traning Hospital, Health Sciences University, Ankara 06110, Turkey
Sertac Cimen, Fatih Sandikci, Department of Urology, Diskapi Research and Traning Hospital, Health Sciences University, Ankara 06110, Turkey
Author contributions: Cimen SG and Cimen S designed the research; Cimen SG and Sandikci F performed research; Gundogmus AG contributed analytic tools; Oguz E and Cimen SG analyzed data; Ayli MD and Cimen SG wrote the paper.
Institutional review board statement: The study was reviewed and approved by the Diskapi Research and Training Hospital Ethics Committee.
Clinical trial registration statement: This study is registered at Diskapi Research and Training Hospital Clinical Trials Registry. The registration identification number is 41303261/iTK.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors of this manuscript having no conflicts of interest to disclose.
Data sharing statement: There is no additional data available.
CONSORT 2010 statement: The authors have read the CONSORT 2010 Statement, and the manuscript was prepared and revised according to the CONSORT 2010 Statement.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Sanem Guler Cimen, FEBS, MD, MSc, Associate Professor, Attending Doctor, Director, Doctor, Surgeon, Department of General Surgery, Diskapi Research and Training Hospital, Health Sciences University, Guvenlik Caddesi No. 87-6, Ankara 06110, Turkey. s.cimen@dal.ca
Received: December 3, 2019
Peer-review started: December 2, 2019
First decision: February 20, 2020
Revised: March 9, 2020
Accepted: March 26, 2020
Article in press: March 26, 2020
Published online: April 29, 2020
Processing time: 141 Days and 21.5 Hours
Abstract
BACKGROUND

Both end-stage renal disease and being wait-listed for a kidney transplant are anxiety-causing situations. Wait-listed patients usually require arteriovenous fistula surgery for dialysis access. This procedure is performed under local anesthesia. We investigated the effects of music on the anxiety, perceived pain and satisfaction levels of patients who underwent fistula surgery.

AIM

To investigate the effect of music therapy on anxiety levels and perceived pain of patients undergoing fistula surgery.

METHODS

Patients who were on a waiting list for kidney transplants and scheduled for fistula surgery were randomized to control and music groups. The music group patients listened to music throughout the fistula surgery. The State-Trait Anxiety Inventory was performed to assess anxiety, additionally visual analog scale was used to evaluate perceived pain, willingness to repeat the procedure and patient satisfaction. Demographic features, comorbidities, surgical history, basic surgical data (location of fistula creation, duration of surgery, incision length) and intra-operative hemodynamic parameters were recorded by an investigator blinded to the study group. An additional trait anxiety assessment was performed following the surgery.

RESULTS

There was a total of 55 patients included in the study. However, 14 patients did not fulfill the criteria due to requirement of sedation during surgery or uncompleted questionnaires. The remaining 41 patients were included in the analysis. There were 26 males and 15 females. The control and music groups consisted of 20 and 21 patients, respectively. With regard to basic surgical and demographic data, there was no difference between the groups. Overall patient satisfaction was significantly higher and intra-operative heart rate and blood pressure were significantly lower in the music group (P < 0.05). Postoperative state anxiety levels were significantly lower in the music group.

CONCLUSION

Music therapy can be a complimentary treatment for patients undergoing fistula surgery. It can reduce anxiety and perceived pain, improve intraoperative hemodynamic parameters and enhance treatment satisfaction, thus may contribute to better compliance of the patients.

Keywords: Music; Music therapy; Anxiety; Arteriovenous fistula; Kidney transplant; Waitlist; State-Trait Anxiety Inventory; Dialysis access; End-stage kidney disease

Core tip: Being successful in managing patients undergoing kidney transplantation goes beyond passing on best medical advice and performing operations with cutting edge technology. It requires building rapport and informing them about the procedures awaiting, like transplantation and arteriovenous fistula creation. However, having to go through these procedures may cause anxiety and feeling powerless. One of our important duty as a physician should be to keep our patients on task and help them manage their anxiety. This article conceptualizes music therapy as an effective tool to relieve patient anxiety during fistula creation surgery by providing randomized, single-blind clinical trial data.