Repeatability of two-dimensional chemical shift imaging multivoxel proton magnetic resonance spectroscopy for measuring human cerebral choline-containing compounds

Table 1 Wilcoxon related-samples signed-rank test results

Voxel	Median Cho/Cr at first scan	Median Cho/Cr at second scan	Wilcoxon related-samples signed-rank test (P value)
1	0.681	0.624	0.345
2	0.825	0.836	0.917
3	0.897	0.924	0.046
4	0.819	0.785	0.917
5	0.822	0.812	0.753
6	0.998	1.060	0.917
7	0.868	0.902	0.600
8	0.661	0.708	0.463
9	0.751	0.579	0.075
10	0.878	0.799	0.028
11	0.970	1.043	0.173
12	0.793	0.860	0.173
13	0.822	0.765	0.600
14	0.993	0.989	0.753
15	0.923	0.894	0.600
16	0.714	0.682	0.463
17	0.760	0.644	0.249
18	0.947	0.855	0.116
19	1.027	1.045	0.345
20	0.751	0.828	0.173
21	0.898	0.816	0.046
22	1.063	1.056	0.173
23	0.942	1.022	0.917
24	0.728	0.747	0.116
25	0.713	0.705	0.249
26	0.941	0.984	0.917
27	0.940	0.961	0.345
28	0.808	0.831	0.753
29	0.853	0.851	0.600
30	1.030	1.083	0.600
31	0.991	0.929	0.249
32	0.709	0.696	0.173
33	0.660	0.660	0.600
34	0.892	0.922	0.345
35	0.948	0.905	0.917
36	0.732	0.718	0.600
37	0.750	0.724	0.345
38	1.032	0.904	0.173
39	0.982	0.946	0.345
40	0.700	0.744	0.116
41	0.627	0.597	0.917
42	0.866	0.854	0.249
43	0.871	0.793	0.600
44	0.591	0.595	0.600
45	0.573	0.584	0.753
46	0.793	0.875	0.600
47	0.903	0.940	0.249
48	0.563	0.686	0.075
49	0.571	0.575	0.463
50	0.779	0.817	0.345
51	0.740	0.777	0.116
52	0.539	0.533	0.463
53	0.546	0.500	0.463
54	0.767	0.752	0.463
55	0.812	0.838	0.046
56	0.530	0.583	0.345
57	0.498	0.507	0.917
58	0.692	0.715	0.463
59	0.607	0.683	0.463
60	0.466	0.472	0.173
61	0.569	0.451	0.173
62	0.825	0.677	0.753
63	0.638	0.639	0.753
64	0.530	0.625	0.600

Table 2 Mean coefficient of variation, repeatability coefficient, and intraclass correlation coefficient for all voxels

Voxel	Mean coefficient of variation	Repeatability coefficient	Intraclass correlation coefficient (P value)
1	0.080	0.159	0.492 (0.236)
2	0.057	0.194	0.866 (0.032)
3	0.028	0.057	0.982 (< 0.0001)
4	0.115	0.386	-1.877 (0.822)
5	0.101	0.260	-0.066 (0.523)
6	0.117	0.446	0.372 (0.335)
7	0.053	0.171	0.829 (0.046)
8	0.076	0.206	0.158 (0.429)
9	0.191	0.607	-0.233 (0.612)
10	0.049	0.113	0.901 (0.003)
11	0.071	0.191	0.702 (0.081)
12	0.091	0.225	0.509 (0.197)
13	0.076	0.213	0.724 (0.100)
14	0.078	0.233	0.696 (0.124)
15	0.089	0.277	0.735 (0.105)
16	0.091	0.236	-0.024 (0.509)
17	0.290	1.287	-3.314 (0.949)
18	0.095	0.226	0.811 (0.029)
19	0.058	0.226	0.816 (0.052)
20	0.058	0.137	0.370 (0.273)
21	0.058	0.106	0.569 (0.071)
22	0.064	0.214	0.780 (0.048)
23	0.055	0.238	0.941 (0.005)
24	0.258	6.467	0.152 (0.43)
25	0.192	0.305	0.866 (0.028)
26	0.044	0.129	0.974 (0.001)
27	0.062	0.205	0.833 (0.033)
28	0.087	0.242	0.652 (0.159)
29	0.059	0.170	0.749 (0.088)
30	0.061	0.205	0.851 (0.034)
31	0.046	0.114	0.983 (< 0.001)
32	0.093	0.174	0.907 (0.007)
33	0.126	0.244	0.872 (0.024)
34	0.057	0.146	0.829 (0.033)
35	0.066	0.230	0.793 (0.071)
36	0.063	0.151	0.883 (0.024)
37	0.036	0.079	0.960 (0.002)
38	0.096	0.314	0.397 (0.284)
39	0.087	0.269	-0.162 (0.584)
40	0.122	0.222	0.643 (0.116)
41	0.185	0.225	0.917 (0.011)
42	0.055	0.138	0.950 (0.002)
43	0.083	0.235	0.691 (0.132)
44	0.106	0.217	0.553 (0.216)
45	0.106	0.369	0.229 (0.397)
46	0.182	0.547	-0.256 (0.588)
47	0.054	0.136	0.942 (0.003)
48	0.175	0.274	-0.074 (0.555)
49	0.102	0.134	0.961 (0.002)
50	0.053	0.121	0.970 (0.001)
51	0.039	0.081	0.946 (0.001)
52	0.056	0.116	0.870 (0.03)
53	0.068	0.134	0.795 (0.064)
54	0.071	0.171	0.928 (0.007)
55	0.083	0.117	0.945 (0.001)
56	0.148	0.277	0.108 (0.448)
57	0.195	0.296	0.887 (0.022)
58	0.340	0.547	0.582 (0.188)
59	0.177	0.384	0.143 (0.43)
60	0.135	0.177	0.883 (0.011)
61	0.143	0.230	0.620 (0.135)
62	0.200	0.691	0.512 (0.253)
63	0.180	0.432	0.833 (0.046)
64	0.273	0.714	-0.957 (0.73)