Fertility concerns in reproductive-aged breast cancer patients: Correlation with negative psychology and social relationship quality, and influencing factors

Table 1 Reproductive Concerns After Cancer Scale-based fertility concern assessment in reproductive-aged breast cancer patients

Indicators	Score
Personal health (points)	9.00 (7.00, 12.00)
Child’s health (points)	9.00 (6.00, 11.00)
Acceptance (points)	8.00 (6.00, 10.00)
Becoming pregnant (points)	8.00 (6.00, 10.00)
Fertility potential (points)	8.00 (6.00, 10.00)
Partner disclosure (points)	7.00 (5.00, 10.00)
RCAC (points)	49.56 ± 6.59

RCAC: Reproductive Concerns After Cancer.

Table 2 Negative psychology evaluation of reproductive-aged breast cancer patients by Self-Rating Anxiety Scale and Self-Rating Depression Scale, n (%)

Indicators	Score
SAS (points), mean ± SD	47.99 ± 6.59
No anxiety	95 (62.09)
Mild anxiety	50 (32.68)
Moderate anxiety	8 (5.23)
Anxiety rate	58 (37.91)
SDS (points)	50.32 ± 5.85
No depression	98 (64.05)
Mild depression	53 (34.64)
Moderate depression	2 (1.31)
Depression rate	55 (35.95)

SAS: Self-Rating Anxiety Scale; SDS: Self-Rating Depression Scale.

Table 3 Evaluation of social relationship quality of reproductive-aged breast cancer patients by Social Relational Quality Scale, mean ± SD

Indicators	Score
Friendship (points)	12.28 ± 3.25
Family intimacy (points), median (interquartile range)	19.00 (17.00, 23.00)
Family commitment (points)	13.33 ± 3.31
SRQS (points)	45.04 ± 7.04

SRQS: Social Relational Quality Scale.

Table 4 Univariate analysis, mean ± SD/median (interquartile range)

Indicators	n	RCAC (points)	t/Z	P value
Age (years)			0.027	0.979
< 30	105	49.57 ± 6.12
≥ 30	48	49.54 ± 7.59
Marital status			1.991	0.048
Married	107	50.25 ± 6.84
Single	46	47.96 ± 5.71
Employment status			-5.700	< 0.001
Unemployed	87	47.00 (43.00, 52.00)
Employed	66	53.00 (50.00, 56.00)
Educational level			5.431	< 0.001
Senior high school or above	83	52.00 ± 5.60
Below senior high school	70	46.67 ± 6.54
Residence			0.636	0.526
Rural	51	49.08 ± 6.75
Urban	102	49.80 ± 6.53
Annual income (in ten thousand yuan)			2.905	0.004
< 4	76	51.08 ± 6.50
≥ 4	77	48.06 ± 6.36
Number of children			2.631	0.009
0-1	62	51.23 ± 7.00
≥ 2	91	48.43 ± 6.07
Fertility desire			-3.488	0.002
Yes	46	53.00 (49.50, 55.50)
No	107	48.00 (44.00, 53.00)
Fertility preservation			0.383	0.702
Yes	15	48.07 ± 8.56
No	138	49.72 ± 6.36
SAS (points)			0.191	0.849
< 50	95	49.64 ± 6.21
≥ 50	58	49.43 ± 7.22
SDS (points)			-4.689	< 0.001
< 53	98	48.00 (43.00, 53.00)
≥ 53	55	53.00 (50.00, 57.00)
SRQS (points)			0.938	0.350
< 45	75	49.05 ± 5.91
≥ 45	78	50.05 ± 7.19

RCAC: Reproductive Concerns After Cancer; SAS: Self-Rating Anxiety Scale; SDS: Self-Rating Depression Scale; SRQS: Social Relational Quality Scale.

Table 5 Multivariate analysis

Indicators	Unstandardized coefficient		Standardized beta coefficient	t	P value	95%CI for B
	B	SE				Lower bound	Upper bound
Marital status	-2.219	0.972	-0.155	-2.283	0.024	-4.139	-0.298
Employment status	2.170	0.907	0.164	2.392	0.018	0.378	3.962
Educational level	-2.248	0.900	-0.171	-2.498	0.014	-4.027	-0.470
Annual income	-3.886	0.919	-0.296	-4.226	< 0.001	-5.703	-2.068
Number of children	-2.369	0.924	-0.177	-2.565	0.011	-4.195	-0.544
Fertility desire	0.650	0.970	0.045	0.670	0.504	-1.267	2.567
SDS	2.958	0.951	0.216	3.110	0.002	1.078	4.839

CI: Confidence interval; SDS, Self-Rating Depression Scale.