Correlation of postoperative anxiety and depression with fear of cancer recurrence and sleep disorders in oral cancer patients

Table 1 Correlation analysis results

Indicator	r	P value
HADS-A and FoP-Q-SF	0.359	< 0.001
HADS-A and PSQI	0.369	< 0.001
HADS-D and FoP-Q-SF	0.322	< 0.001
HADS-D and PSQI	0.484	< 0.001

FoP-Q-SF: Fear of Progression Questionnaire-Short Form; PSQI: Pittsburgh Sleep Quality Index; HADS-A: Hospital Anxiety and Depression Scale-Anxiety subscale; HADS-D: Hospital Anxiety and Depression Scale-Depression subscale.

Table 2 Univariate analysis of factors influencing anxiety or depression in oral cancer patients, n (%)

Indicator	Anxiety or depression group (n = 89)	Control group (n = 58)	χ2 value	P value
Age (years)			0.384	0.536
< 60 (n = 79)	46 (51.69)	33 (56.90)
≥ 60 (n = 68)	43 (48.31)	25 (43.10)
Gender			1.008	0.315
Male (n = 81)	52 (58.43)	29 (50.00)
Female (n = 66)	37 (41.57)	29 (50.00)
Married			0.566	0.452
No (n = 51)	33 (37.08)	18 (31.03)
Yes (n = 96)	56 (62.92)	40 (68.97)
Educational level			4.990	0.026
Below high school (n = 85)	58 (65.17)	27 (46.55)
High school or above (n = 62)	31 (34.83)	31 (53.45)
Monthly income (RMB)			1.804	0.179
< 4000 (n = 81)	53 (59.55)	28 (48.28)
≥ 4000 (n = 66)	36 (40.45)	30 (51.72)
Smoking			0.783	0.376
Absent (n = 77)	44 (49.44)	33 (56.90)
Present (n = 70)	45 (50.56)	25 (43.10)
Alcohol abuse			0.025	0.874
Absent (n = 85)	51 (57.30)	34 (58.62)
Present (n = 62)	38 (42.70)	24 (41.38)
Pathological stage			4.673	0.031
T1-2 (n = 88)	47 (52.81)	41 (70.69)
T3-4 (n = 59)	42 (47.19)	17 (29.31)
Recurrence			9.636	0.002
Absent (n = 73)	35 (39.33)	38 (65.52)
Present (n = 74)	54 (60.67)	20 (34.48)
FoP-Q-SF (points)			11.963	< 0.001
< 40 (n = 63)	28 (31.46)	35 (60.34)
≥ 40 (n = 84)	61 (68.54)	23 (39.66)
PSQI (points)			5.010	0.025
< 9 (n = 43)	20 (22.47)	23 (39.66)
≥ 9 (n = 104)	69 (77.53)	35 (60.34)

FoP-Q-SF: Fear of Progression Questionnaire-Short Form; PSQI: Pittsburgh Sleep Quality Index.

Table 3 Multivariate analysis of factors influencing anxiety or depression in oral cancer patients

Indicator	β	SE	Wald	P value	OR	95%CI
Educational level	-0.807	0.396	4.156	0.041	0.446	0.206-0.969
Pathological stage	0.705	0.409	2.971	0.085	2.023	0.908-4.508
Recurrence	1.185	0.398	8.873	0.003	3.272	1.500-7.137
FoP-Q-SF (points)	1.593	0.399	15.916	< 0.001	4.917	2.248-10.752
PSQI (points)	0.818	0.426	3.686	0.055	2.267	0.983-5.228

FoP-Q-SF: Fear of Progression Questionnaire-Short Form; PSQI: Pittsburgh Sleep Quality Index; OR: Odds ratio; CI: Confidence interval.