Risk factors for depression in patients in perimenopause with cervical cancer

Table 1 Risk level assignment table for related factors of depression in patients in perimenopause with cervical cancer

Variable	Serial number	Assignment
Age (years)	1	0 ≤ 50, 1 ≥ 50
BMI (kg/m²)	2	0 ≤ 24, 1 ≥ 24
Household registration	3	0 = urban, 1 = rural
Occupational status	4	0 = employed, 1 = retired or unemployed
Education	5	0 = junior high school and below, 1 = high school and above
Monthly household income	6	0 ≤ 4000, 1 ≥ 4000
Medical payment method	7	0 = medical insurance, 1 = self-funded
Marital status	8	0 = single, divorced, or widowed, 1 = married
Fertility status	9	0 = no children, 1 = children
Social support	10	0 = low, 1 = high
Self-management effectiveness	11	0 = low, 1 = high
Smoking history	12	0 = yes, 1 = no
Drinking history	13	0 = yes, 1 = no
Basic medical history	14	0 = yes, 1 = no
Family history of cervical cancer	15	0 = yes, 1 = no
Disease	16	0 = first onset, 1 = recurrence
Pathological classification	17	0 = squamous cell carcinoma, 1 = non-squamous cell carcinoma
Pathological staging	18	0 = Stage I, Stage II, 1 = Stage III, Stage IV
Pain level	19	0 = low, 1 = high
Sleep quality	20	0 = low, 1 = high

BMI: Body mass index.

Table 2 Comparison of baseline data between the two groups of patients

Variable	Total (n = 254)	No depression group (n = 152)	Depression group (n = 102)	t/χ2	P value
Age (years)				0.011	0.918
< 50	128	77 (50.66)	51 (50.00)
≥ 50	126	75 (49.34)	51 (50.00)
BMI (kg/m²)				3.107	0.078
< 26	37	27 (17.76)	10 (9.80)
≥ 26	217	125 (82.24)	92 (90.20)
Household registration				0.010	0.920
City	123	74 (48.68)	49 (48.04)
Rural	131	78 (51.32)	53 (51.96)
Occupational status				2.380	0.123
Working	76	51 (33.55)	25 (24.51)
Retired or unemployed	178	101 (66.45)	77 (75.49)
Education				0.016	0.900
Junior high school and below	168	101 (66.45)	67 (65.69)
High school and above	86	51 (33.55)	35 (34.31)
Monthly household income, CNY				103.572	0.000
< 4000	78	10 (6.58)	68 (66.67)
≥ 4000	176	142 (93.42)	34 (33.33)
Medical payment method				0.005	0.942
Health insurance	170	102 (67.11)	68 (66.67)
Self-funded	84	50 (32.89)	34 (33.33)
Marital status				3.235	0.072
Single, divorced, or widowed	112	74 (48.68)	38 (37.25)
Married	142	78 (51.32)	64 (62.75)
Fertility status				0.006	0.940
No children	22	13 (8.55)	9 (8.82)
Children	232	139 (91.45)	93 (91.18)
Social support				6.050	0.014
Low	156	84 (55.26)	72 (70.59)
High	98	68 (44.74)	30 (29.41)
Self-management effectiveness				0.000	0.992
Low	152	91 (59.87)	61 (59.80)
High	102	61 (40.13)	41 (40.20)
Smoking history				0.097	0.756
Have	135	82 (53.95)	53 (51.96)
None	119	70 (46.05)	49 (48.04)
Drinking history				0.071	0.789
Have	147	89 (58.55)	58 (56.86)
None	107	63 (41.45)	44 (43.14)
Basic medical history				0.165	0.684
Have	138	81 (53.29)	57 (55.88)
None	116	71 (46.71)	45 (44.12)
Family history of cervical cancer				0.319	0.572
Have	154	90 (59.21)	64 (62.75)
None	100	62 (40.79)	38 (37.25)
Disease				4.647	0.031
Initial	159	87 (57.24)	72 (70.59)
Relapse	95	65 (42.76)	30 (29.41)
Pathological classification				0.021	0.885
Squamous cell carcinoma	188	113 (74.34)	75 (73.53)
Non-squamous cell carcinoma	66	39 (25.66)	27 (26.47)
Pathological staging				20.816	0.000
Phase I, Phase II	119	89 (58.55)	30 (29.41)
Stage III, Stage IV	135	63 (41.45)	72 (70.59)
Pain level				24.286	0.000
Low	135	100 (65.79)	35 (34.31)
High	119	52 (34.21)	67 (65.69)
Sleep quality				30.769	0.000
Low	118	49 (32.24)	69 (67.65)
high	136	103 (67.76)	33 (32.35)

Data are presented as mean ± SD or n (%). BMI: Body mass index; CNY: China yuan.

Table 3 Results of multivariate logistic regression analysis of depression in perimenopausal patients with cervical cancer

Variable	Multifactorial
	Beta	OR	95%CI	P value
Monthly household income	3.484	32.606	12.742-83.436	3.63e-13
Disease	1.454	4.282	1.760-10.420	0.0013
Social support	0.525	1.691	0.763-3.745	0.1955
Pathological staging	1.454	4.123	1.849-9.193	0.0005
Pain level	0.166	1.181	0.080-1.411	4.34e-05
Sleep quality	1.129	3.094	1.431-6.689	0.0041

OR: Odds ratio; CI: Confidence interval.